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Prostaglandins in Cellular Biology pp 269–291Cite as

Formation of Prostaglandins in the Skin Following a Burn Injury

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Part of the book series: Alza Conference Series ((ALZA,volume 1))

Abstract

Two phases are discerned in the vascular response to a burn injury, one immediate, lasting 5–10 min, and one delayed starting after about 30 min and lasting several hours to days. Histamine has been suggested as a mediator of the first phase of the inflammatory response, and vasoactive polypeptides have been implied in the delayed phase (Spector and Willoughby, 1968). In the following we shall describe results showing that prostaglandin E(2) is formed in the skin following a burn injury, and may thus be an additional mediator in the delayed phase of the tissue response to a burn injury.

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Author information

Authors and Affiliations

  1. Dept. of Pharmacology, Karolinska Inst., Stockholm, Sweden

    E. Anggard & C.-E. Jonsson

  2. The Burn Centre, Dept. of Plastic Surgery, University Hospital, Uppsala, Sweden

    E. Anggard & C.-E. Jonsson

Authors
  1. E. Anggard
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  2. C.-E. Jonsson
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Editor information

Editors and Affiliations

  1. ALZA Corporation, Palo Alto, California, USA

    Peter W. Ramwell  & Bruce B. Pharriss  & 

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© 1972 Plenum Press, New York

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Anggard, E., Jonsson, CE. (1972). Formation of Prostaglandins in the Skin Following a Burn Injury. In: Ramwell, P.W., Pharriss, B.B. (eds) Prostaglandins in Cellular Biology. Alza Conference Series, vol 1. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-2844-5_13

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  • DOI: https://doi.org/10.1007/978-1-4684-2844-5_13

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4684-2846-9

  • Online ISBN: 978-1-4684-2844-5

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