Abstract
The interstitial fluid bathing the cells must be constantly replenished and readjusted in its composition, since it functions as a source of nutrition for the cells. The circulating blood supplies the means for this adjustment by supporting continuous exchange of fluid and solutes between blood and interstitial fluid in the capillary bed.(1–3) The mechanisms for this action will now be examined.
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Selected Reading—Steady State Between Plasma and Interstitial Fluid; Lymph, Edema
Rusznyak, I., Földi, M., and Szabó, G., Lymphatics and Lymph Circulation. Physiology and Pathology, 2nd Ed., Pergamon, New York (1968).
Mayerson, H. S., Ed., Lymph and the Lymphatic System (Proc. Conf. on Lymph and the Lymphatic System), C. C. Thomas, Springfield, Illinois (1968).
McMaster, P. D., Ed., Lymph, Ann. N.Y. Acad. Sci. 46 (8):679–882 (1946)
Yoffey, J. M. and Courtice, F. C., Lymphatics, Lymph and Lymphoid Tissue, Harvard Univ. Press, Cambridge, Massachusetts (1956).
Moyer, J. H. and Fuchs, M., Ed., Edema, Mechanisms and Management, Saunders, Philadelphia, Pennsylvania (1960).
Battezzati, M. and Donini, I., Lymphatic System (translated from Italian), Halsted Press, Wiley, New York (1973).
References
Zweifach, B. W. and Intaglietta, M., Fluid exchange across the blood capillary interface, Fed. Proc. 25: 17841788 (1966).
Burton, A. C., Role of geometry, of size and shape, in the microcirculation, Fed. Proc. 25: 1753–1760 (1966).
Renkin, E. M., Capillary blood flow and transcapillary exchange, Physiologist 9: 361–366 (1966).
Arturson, G., Areskog, N. H., and Arfors, K., The transport of macromolecules across the blood lymph barrier. Influence of capillary pressure on macro-molecular composition of lymph. Bibl. Anat. 10: 228–233 (1969).
Rhodin, J. A. G., The ultrastructure of mammalian arterioles and precapillary sphincters, J. Ultrastruct. Res. 18: 181–223 (1967).
Mellander, S., The regulation of blood flow, Proc. Roy. Soc. Med. 61: 55–61 (1968).
Johnson, P. C. and Wayland, H., Regulation of blood flow in single capillaries, Am. J. Physiol. 212: 1405–1415 (1967).
Starling, E. H., On absorption of fluids from the connective tissue spaces, J. Physiol. 19: 312–326 (1896).
Hyman, C., Physiologic function of the lymphatic system, Cancer Chemotherap. Rep. 58: 25–30 (1969).
Langgard, H., The subcutaneous absorption of albumin in edematous states, Acta Med. Scand. 174: 645–650 (1963).
Threefoot, S. A., Gross and microscopic anatomy of the lymphatic vessels and lymphaticovenous communications, Cancer Chemotherap. Rep. 58:1–20 (1968). 10a.
Lauweryns, J. M., The blood and lymphatic microcirculation of the lung.Pathology Annual 6:365–415 (1971).
Mayerson, H. S., Lymph and Lymphatics, Circulation 28: 839–842 (1963).
Courtice, F. C., Harding, J., and Steinbeck, A. W., The removal of free red blood cells from the peritoneal cavity of animals, Aust. J. Exp. Biol. Med. Sci. 31: 215–225 (1953).
McMaster, P. D., Conditions in the skin influencing interstitial fluid movement, lymph formation and lymph flow, Ann. N.Y. Acad. Sci. 46: 743–787 (1946).
Ludwig, J., Linhart, P., and Baggenstoss, A. H., Hepatic lymph drainage in cirrhosis and congestive heart failure, Arch. Pathol. 86: 551–562 (1968).
Bloom, B., Chaikoff, I. L., and Reinhardt, W. O., Intestinal lymph as pathway for transport of absorbed fatty acids of different chain lengths, Am. J. Physiol. 166: 451–455 (1951).
Hellman, L., Frazell, E. L., and Rosenfeld, R. S., Direct measurement of cholesterol absorption via the thoracic duct in man, J. Clin. Invest. 39: 12881294 (1960).
Daniel, P. M., Gale, M., and Pratt, O. E., Hormones and related substances in the lymph leaving four endocrine glands-The testis, ovary, adrenal and thyroid, Lancet 1: 1223–1234 (1963).
Lever, A. F. and Peart, W. S., Renin and angiotensin-like activity in renal lymph, J. Physiol. 160: 548–563 (1962).
Doemling, D. B. and Steggerda, F. R., Stimulation of thoracic duct lymph flow by epinephrine and norepinephrine, Proc. Soc. Exp. Biol. Med. 110: 811–813 (1962).
Werner, B., The biochemical composition of the human thoracic duct lymph, Acta Clin. Scand. 132: 63–76 (1966).
Ianlez, L. E., Guimaraes, F. R., and Sabbaga, E., Biochemical composition of thoracic duct lymph fluid in chronic renal patients, Rev. Hosp. Clin. Fac. Med. S. Paulo 28: 141–146 (1973).
Szabó, G., Gergely, J., and Magyar, Z., Immunoelectrophoretic analysis of the lymph, Experientia 19: 98–99 (1963).
Blomstrand, R., Nilsson, I. M., and Dahlback, O., Coagulation studies on human thoracic duct lymph, Scand. J. Clin. Lab. Invest. 15: 248–254 (1963).
Bartlett, R. H., Falor, W. H., and Zarafonetis, C. J. D., Lipid studies on human lymph and chyle, J. Am. Med. Assoc. 187: 126–127 (1964).
Gersh, I. and Catchpole, H. R., The nature of ground substance of connective tissue, Perspect. Biol. Med. 3: 282–319 (1960).
Seki, K., Yamane, Y., Shinoura, A., Koide, K., Uechi, M., Mori, K., Nagasaki, M., and Yoshitoshi, Y., Experimental and clinical studies on the lymph circulation, Am. Heart. J. 75: 620–629 (1968).
Losowsky, M. S., Alltree, E. M., and Atkinson, M., Plasma colloid osmotic pressure and its relation to protein fractions, Clin. Sci. 22: 249–257 (1962).
Hollander, W., Reilly, P., and Burrows, B. A., Lymphatic flow in human subjects as indicated by the disappearance of 1131 labeled albumin from the subcutaneous tissues, J. Clin. Invest. 35: 713 (1956).
Castell, D. O., Ascites in cirrhosis. Relative importance of portal hypertension and hypoalbuminemia, Am. J. Dig. Dis. 12: 916–922 (1967).
Wolff, H. P., Blaise, B. H., and Düsterdieck, G., Role of aldosterone in edema formation, Ann. N.Y. Acad. Sci. 139: 285–294 (1962).
Van Tongeren, J. H. and Reichert, W. J., Demonstration of protein-losing gastroenteropathy. The quantitative estimation of gastrointestinal protein loss using 61Cr-labeled plasma proteins, Clin. Chim. Acta 14: 42–48 (1966).
Kerr, R. M., Du Bois, J. J., and Holt, P. R., Use of 1251 and 61Cr labeled albumin for the measurement of gastrointestinal and total albumin catabolism, J. Clin. Invest. 46: 2064–2082 (1967).
Dobbins, W. O., Diseases associated with protein losing enteropathy: Electromicroscopic studies of the intestinal mucosa, South. Med. J. 60: 1077–1081 (1967).
Kocen, R. S. and Atkinson, M., Ascites in hypothyroidism, Lancet 1: 527–531 (1963).
Thorn, G. W., Approach to the patient with “idiopathic edema” of “periodic swelling, ” J. Am. Med. Assoc. 206: 333–338 (1968).
Vorburger, C., Pathogenesis of edema, Angiology 19: 362–371 (1968).
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© 1975 Plenum Press, New York
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Natelson, S., Natelson, E.A. (1975). Mechanisms for Maintenance of a Steady State Between Plasma and Interstitial Fluid. In: Principles of Applied Clinical Chemistry Chemical Background and Medical Applications. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2745-5_9
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DOI: https://doi.org/10.1007/978-1-4684-2745-5_9
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