Abstract
Born and raised in Vermont, I graduated from Middlebury College in 1937 with an A.B. in biology and an interest in enzymes and hormones. Actually I had gone to college to major in music but had switched majors after a month in Longwell’s course in general biology. The interest in enzymes and hormones had been stimulated by Barney, the other member of Middlebury’s two-man biology department. On graduation I was lucky enough to win Middlebury’s Dutton Traveling Fellowship, which provided for a year’s study abroad, and I registered in physiology and biochemistry at Cambridge University. Two years before the start of World War II, British physiology was very excited about acetylcholine, Cholinesterase, and neurohumoral transmission, and Dale and Loewi had just received the Nobel Prize for their research on humoral mediation of the nerve impulse. In England Dale, Feldberg, Gaddum, and Vogt were advancing neurohumoral concepts, and Adrian in his first year as professor of physiology at Cambridge was transmitting them sympathetically, although he was himself a Nobel Laureate in electrophysiology. Marshall (of Physiology of Reproduction fame) lectured to us about sex behavior in cats, and steroid hormones were stressed in biochemistry. By further good fortune I met two Americans in Cambridge who were influential in my career plans: Donald Barron and Edgar Boell.
Research in the author’s laboratory has been supported largely by grants from the National Institutes of Health and The Ford Foundation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Beach, F. A. (1948). Hormones and Behavior. Hoeber, New York.
Beyer, C., and C. H. Sawyer (1969). Hypothalamic unit activity related to control of the pituitary gland. Pages 255–287 in L. Martini and W. F. Ganong, eds. Frontiers in Neuroendoerinology 1969. Oxford University Press, Oxford, England.
Everett, J. W. (1960). The mammalian female reproductive cycle and its controlling mechanisms. Pages 495 555 in W. C. Young, ed. Sex and Internal Secretions. Williams and Wilkins, Baltimore.
Harris, G. W. (1955). Neural Control of the Pituitary Gland. Edward Arnold, London.
Hilliard, J., H. G. Spies, and C. H. Sawyer (1969). Hormonal factors regulating ovarian cholesterol mobilization and progestin secretion in intact and hypophysectomized rabbits. Pages 55–92 in K. W. McKerns, ed. The Gonads. Appleton, Century-Crofts, New York.
Kawakami, M. and C. H. Sawyer (1967). Effects of sex hormones and antifertility steroids on brain thresholds in the rabbit. Endocrinology 80: 857.
Markee, J. E., J. W. Everett, and C. H. Sawyer (1952). The relationship of the nervous system to the release of gonadotrophin and the regulation of the sex cycle. Pages 139 - 163 in G. Pincus, ed. Recent Progress in Hormone Research, Vol. 7. Academic Press, New York.
Markee, J. E., C. H. Sawyer, and W. H. Hollinshead (1946). Activation of the anterior hypophysis by electrical stimulation in the rabbit. Endocrinology 38: 345.
Sawyer, C. H. (1947). Cholinergic stimulation of the release of melanophore hormone by the hypophysis in salamander larvae. J. Exp. Zool. 106: 145.
Sawyer, C. H. (1959). Nervous control of ovulation. Pages 1–20 in C. W. Lloyd, ed. Recent Progress in the Endocrinology of Reproduction. Academic Press, New York.
Sawyer, C. H. (1962). Mechanisms by which drugs and hormones activate and block release of pituitary gonadotropins. Pages 27–46 in R. Guillemin, ed. Proceedings of the First International Pharmacological Meeting, vol. 1. Pergamon Press, New York.
Sawyer, C. H. (1963). Neuroendocrine blocking agents and gonadotropin release. Pages 444–459 in A. V. Nalbandov, ed. Advances in Neuroendoerinology. University of Illinois Press, Urbana.
Sawyer, C. H. (1967). Effects of hormonal steroids on certain mechanisms in the adult brain. Proceedings of the Second International Symposium on Hormonal Steroids. Excerpta Medica, Int. Congr. Series No. 132, p. 763.
Sawyer, C. H. (1969a). Regulatory mechanisms of secretion of gonadotrophic hormones. Pages 389–422 in W. Anderson, W. Haymaker, and W. J. H. Nauta, eds. The Hypothalamus. Charles C Thomas, Fort Lauderdale, Florida.
Sawyer, C. H. (1969b). Some effects of hormones on sleep. Exp. Med. Surg. 27: 177.
Sawyer, C. H. (1970). Some endocrine applications of electrophysiology. Pages 389 430 in L. Martini, M. Motta, and F. Fraschini, eds. The Hypothalamus. Academic Press, New York.
Sawyer, C. H., J. W. Everett, and J. D. Green (1954). The rabbit diencephalon in stereotaxic coordinates. J. Comp. Neurol. 101: 801.
Sawyer, C. H., J. W. Everett, and J. E. Markee (1949). A neural factor in the mechanism by which estrogen induces the release of luteinizing hormone in the rat. Endocrinology 41: 218.
Sawyer, C. H., and R. A. Gorski, eds. (1971). Steroid Hormones and Brain Function. UCLA Forum Medical Sciences No. 15, University of California Press, Los Angeles.
Sawyer, C. H., J. Hilliard, S. Kanematsu, R. Scaramuzzi, and C. A. Blake (1974). Effects of intraventricular infusions of norepinephrine and dopamine on LH release and ovulation in the rabbit. Neuroendocrinology 15: 328.
Sawyer, C. H., and M. Kawakami (1961). Interactions between the central nervous system and hormones influencing ovulation. Pages 79–100 in C. A. Villee, ed. Control of Ovulation. Pergamon Press, New York.
Sawyer, C. H., M. Kawakami, and S. Kanematsu (1966). Neuroendocrine aspects of reproduction. Pages 43, 59 85 in Endocrines and the Central Nervous System. Res. Publ. Assoc. Res. Nerv. Ment. Dis. Chap. 4.
Sawyer, C. H., M. Kawakami, J. E. Markee, and J. W. Everett (1959). Physiological studies on some interactions between the brain and the pituitary-gonad axis in the rabbit. Endocrinology 65: 614 688 (five papers).
Sawyer, C. H., J. E. Markee, and B. F. Townsend (1949). Cholinergic and adrenergic components in the neurohumoral control of the release of LH in the rabbit. Endocrinology 44: 18.
Weiner, R. I., R. A. Gorski, and C. H. Sawyer (1972). Hypothalamic catecholamines and pituitary gonadotrophic function. Pages 236 244 in K. M. Knigge, D. E. Scott, and A. Weindl, eds. Brain-Endocrine Interaction, Median Eminence: Structure and Function. S. Karger, AG, Basel.
Wolstenholme, G. E. W., ed. (1952). Anterior Pituitary Secretion. Ciba Foundation Colloquia on Endocrinology, vol. 4. J & A Churchill, London.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1975 Plenum Press, New York
About this chapter
Cite this chapter
Sawyer, C.H. (1975). Twenty-Five Years in Neuroendocrinology of Reproduction (1945–1970). In: Meites, J., Donovan, B.T., McCann, S.M. (eds) Pioneers in Neuroendocrinology. Perspectives in Neuroendocrine Research, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2652-6_16
Download citation
DOI: https://doi.org/10.1007/978-1-4684-2652-6_16
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-2654-0
Online ISBN: 978-1-4684-2652-6
eBook Packages: Springer Book Archive