Proteolytic Activity in CSF

  • P. T. Richards
  • M. Louise Cuzner
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 100)


Proteolytic enzyme activity, present at both acid and neutral pH values, in cerebrospinal fluid canbe measured by a sensitive assay, which monitors the rate of125 I-basic protein breakdown on polyacrylamide gel electrophoresis. CSF cellular neutral proteinase and supernatant acid proteinase are increased in acute multiple sclerosis and in CNS infections.


Multiple Sclerosis Multiple Sclerosis Patient Basic Protein Optic Neuritis Multiple Sclerosis Lesion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • P. T. Richards
    • 1
  • M. Louise Cuzner
    • 1
  1. 1.Department of Neurochemistry, Institute of NeurologyThe National HospitalUK

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