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Charcoal Hemoperfusion: Georgetown University Hospital Experience

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Artificial Kidney, Artificial Liver, and Artificial Cells

Abstract

At Georgetown University Hospital, interest in charcoal hemoperfusion as a means of facilitating toxin removal from blood has shown a doubled peaked history. After the pioneering work of Yatzidis, et al (1) in 1965 in the treatment of barbiturate poisoning, DeMyttenaere, Maher, and Schreiner in 1967 demonstrated the effectiveness of charcoal hemoperfusion in the treatment of glutethimide overdosage in dogs (2). Unfortunately, because of the significant and potentially life threatening dangers of thrombocytopenia and charcoal embolization, charcoal hemoperfusion was not pursued as an attractive therapeutic modality for toxin removal in clinical practice.

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References

  1. Yatzidis, H., Oreopoulos, D., and Triantaphyllidis, D. Treatment of seven barbiturate poisonings. Lancet 1:216–217, 1965.

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© 1978 Plenum Press, New York

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Gelfand, M.C. (1978). Charcoal Hemoperfusion: Georgetown University Hospital Experience. In: Chang, T.M.S. (eds) Artificial Kidney, Artificial Liver, and Artificial Cells. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2478-2_13

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  • DOI: https://doi.org/10.1007/978-1-4684-2478-2_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2480-5

  • Online ISBN: 978-1-4684-2478-2

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