Skip to main content
SpringerLink
Log in

The Biological Basis of Aging

  • Chapter
Frontiers of Medicine

  • 56 Accesses

Abstract

It is indeed a privilege to participate in the celebration of the 50th anniversary of the University of Rochester Medical Center. I am even more gratified by the recognition of the importance of aging and the impact it will have on health and, especially, the quality of human life in the future. I would not, however, have identified the later years of life in the human with the stereotype of senility described by Shakespeare in “As You Like It” as the Seventh Age of Man.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. U. S. Atomic Energy Commission, Brookhaven National Laboratory. (BLN 854) (T340), 34: 1–11, 1964.

    Google Scholar 

  2. Sacher, G. A. In: P. J. Lindop and G. A. Sacher (eds.) , Radiation and Ageing, Taylor &Francis, London, 1966, pp, 411–441.

    Google Scholar 

  3. U. S. Vital Statistics. Abridged Life Tables, United States, 1974.

    Google Scholar 

  4. Rockstein, M., and H. M. Lieberman, Gerontologia 3:23–26, 1959.

    Article  Google Scholar 

  5. Liu, R. K., and R. L. Walford, Nature (Lond.) 212:1277–1278, 1966.

    Article  Google Scholar 

  6. McCay, C., L. S. Sperling, and L. L. Barnes, Arch. Biochem. 2:469–479, 1943.

    Google Scholar 

  7. Kohn, R. R. In: P. J. Lindop and G. A. Sacher (eds.), Radiation and Ageing, Taylor &Francis, London, 1966, pp. 373–392.

    Google Scholar 

  8. Verzar, F. In: D. A. Hall (ed.), International Review of Connective Tissue Research, Vol. 2, Academic Press, New York &London, 1964, pp. 243–300.

    Google Scholar 

  9. Brandfonbrener, M., M. Landowne, and N. W. Shock, Circulation, 12:557–566, 1955.

    Article  Google Scholar 

  10. Shock, N. W. In: F. C. Jeffers (ed.), Proceedings of Seminars 1959–1961, Council on Gerontology, Duke University, Durham, N. C., 1962, pp. 123–140.

    Google Scholar 

  11. Andrew, W., N. W. Shock, C. H. Barrows, and M. J. Yiengst, J. Geront. 14:405–414, 1959.

    Article  Google Scholar 

  12. Shock, N. W. In: J. H. Powers (ed.), Surgery of the Aged and Debilitated Patient, W. B. Saunders Co., Philadelphia, 1968, pp. 10–43.

    Google Scholar 

  13. Comfort, A., Ageing: The Biology of Senescence, Holt, Rinehart and Winston, New York, 1964, 365 pp.

    Google Scholar 

  14. Medvedev, Zh. A. In: N. W. Shock (ed.), Perspectives in Experimental Gerontology, Charles C Thomas, Springfield, I11., 1966, pp. 336–350.

    Google Scholar 

  15. Hart, R. W., and R. B. Setlow, Mech. Aging &Develop. 5:67–77, 1976.

    Article  Google Scholar 

  16. Samorajski, T. In: H. Brody, D. Harman, and J. M. Ordy (eds.), Aging, Vol. 1, Raven Press, New York, 1975, pp. 199–214.

    Google Scholar 

  17. Gershon, H., and D. Gershon. Proc. Nat. Acad. Sci., Wash., 70:909–913, 1973.

    Article  Google Scholar 

  18. Bjorksten, J. In: M. Rockstein (ed.), Theoretical Aspects of Aging, Academic Press, New York, 1974, pp. 43–59.

    Google Scholar 

  19. Chvapil, M. In: N. W. Shock (ed.), Perspectives in Experimental Gerontology, Charles C Thomas, Springfield, I11., 1966, pp. 134–155.

    Google Scholar 

  20. Harman, D., J. Geront. 23:476–482, 1968.

    Article  Google Scholar 

  21. Bjorksten, J., E. R. Weyer, and S. M. Ashman, Finska Kemists. Medd. 80:70–87, 1971.

    Google Scholar 

  22. Walford, R. L., The Immunologic Theory of Aging, Williams &Wilkins, Baltimore, 1969, 248 pp.

    Google Scholar 

  23. Roitt, I. M., Essential Immunology, J. B. Lippincott Co., Philadelphia, 1971, 260 pp.

    Google Scholar 

  24. Makinodan, T., and W. J. Peterson, J. Immunol. 93:886–896, 1964.

    Google Scholar 

  25. Makinodan, T., J. Amer. Geriatrics Soc. 24:249–252, 1976.

    Google Scholar 

  26. Sacher, G. A. In: N. W. Shock (ed.), Perspectives in Experimental Gerontology, Charles C Thomas, Springfield, I11., 1966, pp. 326–335.

    Google Scholar 

  27. Meadow, N. D., and C. H. Barrows, J. Geront. 26:302–309, 1971.

    Article  Google Scholar 

  28. Loeb, J., and J. H. Northrop, J. Biol. Chem. 32:103–121, 1917.

    Google Scholar 

  29. Johnson, H. D., L. D. Kintner, and H. H. Kibler, J. Geront. 18:29–36, 1963.

    Article  Google Scholar 

  30. Selye, H., and P. Prioreschi. In: N. W. Shock (ed.), Aging: Some Social and Biological Aspects, AAAS, Washington, D. C., Publ. No. 65, 1960, pp. 261–272.

    Google Scholar 

  31. Curtis, H. J., and K. L. Gebhard. In: Biological Effects of Radiation (Proceedings of 2nd UN International Conference on Peaceful Uses of Atomic Energy, Vol. 22), United Nations, New York, 1959, pp. 53–57.

    Google Scholar 

  32. Curtis, H. J., Biological Mechanisms of Aging, Charles C Thomas, Springfield, I11., 1966, 133 pp.

    Google Scholar 

  33. Shock, N. W. In: M. Rockstein (ed.), Theoretical Aspects of Aging, Academic Press, New York, 1974, pp. 119–136.

    Google Scholar 

  34. Shock, N. W., and A. H. Norris. In: D. Brunner and E. Jokl (eds.), Physical Activity and Aging, S. Karger, Basel, 1970, pp. 92–99.

    Google Scholar 

  35. Hugin, F., A. H. Norris, and N. W. Shock, J. Geront. 15:388–391, 1960.

    Article  Google Scholar 

  36. Suci, G. J., M. D. Davidoff, and W. W. Surwillo, J. Exp. Psychol. 60:242–244, 1960.

    Article  Google Scholar 

  37. Krag, C. L., and W. B. Kountz, J. Geront. 5:227–235, 1950.

    Article  Google Scholar 

  38. Krag, C. L., and W. B. Kountz, J. Geront. 7:61–70, 1952.

    Article  Google Scholar 

  39. Shattuck, G. C., and M. M. Hilferty, Amer. J. Trop. Med. 12:223–245, 1932.

    Google Scholar 

  40. Pickering, G. W., Clin. Sci. 2:209–235, 1936.

    Google Scholar 

  41. Burch, G. E., A. E. Cohn, and C. Neuman, Amer. Heart J. 23:185–196, 1942.

    Article  Google Scholar 

  42. Shock, N. W., Chapt. 25 in J. E. Birren and L. Hayflick (eds.), Handbook of the Biology of Aging, Van Nostrand Reinhold Co., New York, 1976, in press.

    Google Scholar 

  43. Miller, J. H., and N. W. Shock, J. Geront. 8:446–450, 1953.

    Article  Google Scholar 

  44. Andres, R., R. Swerdloff, T. Pozefsky, and D. Coleman. In: L. T. Skeggs, Jr. (ed.), Chemical Pharmacology, Mediaid Inc., New York, 1965, pp. 486–491.

    Google Scholar 

  45. Shock, N. W., and R. Andres. In: D. F. Chebotarev (ed.), Adaptive Capacities of the Aging Organism, Acad. Sci. USSR, Kiev, 1968, pp. 235–254.

    Google Scholar 

  46. Baker, S. P., G. W. Gaffney, N. W. Shock, and M. Landowne, J. Geront. 14:34–47, 1959.

    Article  Google Scholar 

  47. Solomon, D. H., and N. W. Shock, J. Geront. 5, 302–313, 1950.

    Article  Google Scholar 

  48. Roth, G. S. In: V. J. Cristofalo, J. Roberts, and R. C. Adelman (eds.), Explorations in Aging, Plenum Publishing Co., New York, 1975, pp. 195–208.

    Chapter  Google Scholar 

  49. Shock, N. W., Sci. Amer. 206:100–110, 1962.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Gerontology Research Center, National Institute on Aging, National Institues of Health, Bethesda, Maryland, USA

    N. W. Shock Ph.D.

  2. Baltimore City Hospitals, Baltimore, Maryland, USA

    N. W. Shock Ph.D.

Authors
  1. N. W. Shock Ph.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Rochester School of Medicine and Dentistry, Rochester, New York, USA

    Gordon M. Meade M. D. (Coordinator) (Coordinator)

Rights and permissions

Reprints and permissions

Copyright information

© 1977 Springer Science+Business Media New York

About this chapter

Cite this chapter

Shock, N.W. (1977). The Biological Basis of Aging. In: Meade, G.M. (eds) Frontiers of Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2385-3_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-2385-3_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2387-7

  • Online ISBN: 978-1-4684-2385-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation