Skip to main content

Viral Diabetes

  • Chapter
The Diabetic Pancreas

Abstract

A viral etiology for diabetes mellitus was first proposed some 50 years ago by Gunderson,1 who documented an association between community outbreaks of mumps and the occurrence of the juvenile form of the disease (JODY).2 Since that time, epidemiologic observations and annotations in the literature have repeatedly emphasized the role of mumps virus in the causation of diabetes.3–8 More recently, other common human viruses have been implicated in its pathogenesis.9–13

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. E.: J. Infect. Dis., 41: 197, 1927.

    Article  Google Scholar 

  2. Tattersall, R. B., and Fajans, S.S.: Diabetes, 24: 44, 1974.

    Article  Google Scholar 

  3. Harris, H. F.: Boston Med. Surg. J., 140: 465, 1899.

    Article  Google Scholar 

  4. Patrick, A.: Brit. Med. J., 2: 802, 1924.

    Article  CAS  PubMed  Google Scholar 

  5. Kremer, H. U.: Amer. J. Med., 3: 257, 1947.

    Article  CAS  PubMed  Google Scholar 

  6. Hinden, E.: Lancet, 1: 1381, 1962.

    Article  CAS  PubMed  Google Scholar 

  7. Kahana, D., and Berant, M.: Clin. Pediat., 6: 124, 1967.

    Article  CAS  PubMed  Google Scholar 

  8. Suitt, H. A., Hart, B. A., Zielezny, M., and Schlesinger, E. R.: J. Ped., 86: 654, 1975.

    Article  Google Scholar 

  9. Plotkin, S. A., and Kaye, R.: Pediatrics, 46: 650, 1970.

    CAS  PubMed  Google Scholar 

  10. Johnson, G. M., and Tudor, R. B.: Amer. J. Dis. Child., 120: 453, 1970.

    CAS  PubMed  Google Scholar 

  11. Forrest, J. M., Menser, M. A., and Burgess, J. A.: Lancet, 2: 332, 1971.

    Article  CAS  PubMed  Google Scholar 

  12. Adi, F. C.: Brit. Med. J., 1: 183, 1974.

    Article  CAS  PubMed  Google Scholar 

  13. Gamble, D. R., Kinsley, M. L., Fitzgerald, M. G., Bolton, R., and Taylor, K. W.: Brit. Med. J., 3: 627, 1969.

    Article  CAS  PubMed  Google Scholar 

  14. John, H. S.: J. Pediat., 35: 723, 1949.

    Article  CAS  PubMed  Google Scholar 

  15. Adams, S. F.: Arch. Int. Med., 37: 861, 1926.

    Article  Google Scholar 

  16. Danowski, T. S.: Diabetes Mellitus With Emphasis on Children and Young Adults. Williams & Wilkins, Baltimore, 1957, p. 129.

    Google Scholar 

  17. Gamble, D. R.: Postgrad. Med. J., (Suppl. 3) 50: 538, 1974.

    Google Scholar 

  18. Gleason, R., Funk, I., and Craighead, J. E.: Unpublished data.

    Google Scholar 

  19. Bloom, A., Hayes, T. M., and Gamble, D. R.: Brit. Med. J., 2: 580, 1975.

    Article  Google Scholar 

  20. Huff, J. C., Hierholzer, J. C., and Farris, W. A.: Amer. J. Epidemiol., 100: 277, 1974.

    CAS  Google Scholar 

  21. Tattersall, R. B., and Pyke, D. A.: Lancet, 2: 1120, 1972.

    Article  CAS  PubMed  Google Scholar 

  22. Gottlieb, M. S., and Root, H. F.: Diabetes, 17: 693, 1968.

    CAS  PubMed  Google Scholar 

  23. Singal, D. P., and Blajchman, M. A.: Diabetes, 22: 429, 1973.

    CAS  PubMed  Google Scholar 

  24. Nerup, J., Platz, P., Andersen, O. O., Christy, M., Lyngsoe, J., Poulsen, J. E., Ryder, L. P., Thomsen, M., Neilson, L. S., and Svejgaard, A.: Lancet, 2: 864, 1974.

    Article  CAS  PubMed  Google Scholar 

  25. Nelson, P. G., Pyke, D. A., Cudworth, A. G., Woodrow, J. C., and Batchelor, J. R.: Lancet, 2: 193, 1975.

    Article  CAS  PubMed  Google Scholar 

  26. Garovoy, M. R., Carpenter, C. B., Myrberg, S. M., Gleason, R. E., Funk, I. B., and Craighead, J. E.: Transplant. Proc., 9 (1): 177, 1977.

    CAS  PubMed  Google Scholar 

  27. Lendrum R., Walker, G., and Gamble, D. R.: Lancet, 1: 880, 1975.

    Article  CAS  PubMed  Google Scholar 

  28. Maclaren, N. K., Huang, S. E., and Fogh, J.: Lancet, 1: 997, 1975.

    Article  CAS  PubMed  Google Scholar 

  29. MacCuish, A. C., Jordan, J., Campbell, C. J., Cuncan, L. J. P., and Irvine, W. J.: Diabetes, 24: 36, 1975.

    Article  CAS  PubMed  Google Scholar 

  30. Maclaren, N. K., and Huang, S. W.: Science, 192: 64, 1976.

    Article  PubMed  Google Scholar 

  31. Stansfield, O. H., and Warren, S.: N. Engl. J. Med., 198: 686, 1928.

    Article  Google Scholar 

  32. von Meyenburg, H.: Schweiz. Med. Wochenschr., 70: 554, 1940.

    Google Scholar 

  33. LeCompte, P. M.: Arch. Pathol. 66: 450, 1958.

    CAS  Google Scholar 

  34. Steiner, H.: Klin. Wochenschr., 46: 417, 1968.

    Article  CAS  PubMed  Google Scholar 

  35. Gepts, W.: Diabetes, 14: 619, 1965.

    CAS  PubMed  Google Scholar 

  36. Andrews, C., and Pereira, H. G.: Viruses of Vertebrates. Barlliere, Tindall, & Cassell, London, 1967.

    Google Scholar 

  37. Kissling, R. E., Vanella, J. M., and Schaeffer, M.: Proc. Soc. Exp. Biol. Med., 91: 148, 1956.

    CAS  PubMed  Google Scholar 

  38. Warren, J., Russ, S. B., and Jeffries, H.: Proc. Soc. Exp. Biol. Med., 71: 376, 1949.

    CAS  PubMed  Google Scholar 

  39. Gainer, J. H., and Murchison, T. E.: Vet. Med., 56: 173, 1961.

    Google Scholar 

  40. Craighead, J. E., Peralta, P. H., and Shelokov, A.: Proc. Soc. Exp. Biol. Med., 114: 500, 1963.

    CAS  PubMed  Google Scholar 

  41. Zonkers, A. H.: Amer. J. Trop. Med. Hyg., 10: 593, 1961.

    Google Scholar 

  42. Craighead, J. E.: Nature (London) 207: 1268, 1965.

    Article  CAS  Google Scholar 

  43. Pappenheimer, A. M., Kunz, L. J., and Richardson, S.: J. Exp. Med., 94: 45, 1951.

    Article  CAS  PubMed  Google Scholar 

  44. Godman, G. C., Bunting, H., and Melnick, J. L.: Amer. J. Pathol., 28: 223, 1952.

    CAS  Google Scholar 

  45. Platt, H.: Virology, 9: 484, 1959.

    Article  CAS  PubMed  Google Scholar 

  46. Platt, H.: J. Pathol. Bacteriol., 75: 119, 1958.

    Article  Google Scholar 

  47. Murnane, T. G., Craighead, J. E., Mondragon, H., and Shelokov, A.: Science, 131: 498, 1960.

    Article  CAS  PubMed  Google Scholar 

  48. Craighead, J. E.: Amer. J. Pathol. 48: 333, 1966.

    CAS  Google Scholar 

  49. Craighead, J. E., Kanich, R. E., and Kessler, J. B.: Amer. J. Pathol., 74: 287, 1974.

    CAS  Google Scholar 

  50. Craighead, J. E., and Steinke, J.: Amer. J. Pathol., 63: 119, 1971.

    CAS  Google Scholar 

  51. Hayashi, K., Boucher, D. W., and Notkins, A. L.: Amer. J. Pathol., 75: 91, 1974.

    CAS  Google Scholar 

  52. Boucher, D. W. and Notkins, A. L.: J. Exp. Med., 137: 1226, 1973.

    Article  CAS  PubMed  Google Scholar 

  53. Wellmann, K. F., Amsterdam, D., Brancato, P., and Volk, B. W.: Diabetologia, 8: 349, 1972.

    Article  Google Scholar 

  54. Müntefering, H., Schmidt, W. A. K., and Körber, W.: Dtsch. Med. Wochenschr., 96: 693, 1971.

    Article  PubMed  Google Scholar 

  55. Craighead, J. E.: In: Immunity and Autoimmunity in Diabetes Mellitus. Proceedings of the Francqui Foundation Colloquia. Edited by P. A. Bastenie Elsevier, Excerpta Medica, Amsterdam, 1974, p. 227.

    Google Scholar 

  56. Müntefering, H.: Virchow’s Arch. Pathol. Anat., 356: 207, 1972.

    Article  Google Scholar 

  57. Hayashi, K., Boucher, D. W., and Notkins, A. L.: Amer. J. Pathol. 75: 91, 1974.

    CAS  Google Scholar 

  58. Wellmann, K. F., Amsterdam, D., Brooks, S. E., and Volk, B. W.: Proc. Soc. Exp. Biol. Med., 148: 261, 1975.

    CAS  PubMed  Google Scholar 

  59. Boucher, D. W., Hayashi, K., Rosenthal, J., and Notkins, A. L.: J. Infect. Dis., 131: 462, 1975.

    Article  CAS  PubMed  Google Scholar 

  60. Morrow, P., Freedman, A., and Craighead, J. E.: Testosterone affect on diabetes in mice induced with EMC virus. In Preparation.

    Google Scholar 

  61. Craighead, J. E.: Amer. J. Pathol., 48: 375, 1966.

    CAS  Google Scholar 

  62. Debons, A. F., Krimsky, I., Likuski, H. J., From, A., and Cloutier, R. J.: Amer. J. Physiol., 214: 652, 1968.

    CAS  PubMed  Google Scholar 

  63. Ross, M. E., Ondera, T., Brown, K. S., and Notkins, A. L.: Diabetes, 25: 190, 1976.

    Article  CAS  PubMed  Google Scholar 

  64. Craighead, J. E., and Higgins, D.: J. Exp. Med., 139: 414, 1974.

    Article  CAS  PubMed  Google Scholar 

  65. Kromann, I., Vestergaard, B. F., and Nerup, J.: Acta Endocrinol., 76: 670, 1974.

    CAS  Google Scholar 

  66. Yoon, Y. W., and Notkins, A. L.: J. Exp. Med., 143: 1170, 1976.

    Article  CAS  PubMed  Google Scholar 

  67. Kibrick, S., and Benirschke, K.: A’. Engl. J. Med., 255: 883, 1956.

    Article  Google Scholar 

  68. Sussman, M. L., Strauss, L., and Hodes, H. L.: Amer. J. Dis. Child., 97: 183, 1959.

    Google Scholar 

  69. Craighead, J. E.: In: Handbook of Physiology. Sect. 7, Endocrinology. Vol. 1, Endocrine Pancreas. Edited by R. O. Greep, E. B. Astwood, D. F., Steiner, N. Freinkel, and S. R. Geiger. Amer. Physiol. Soc., Washington, Chapt. 19, 1972, p. 315.

    Google Scholar 

  70. Harrison, A. K., Bauer, S. P., and Murphy, F. A.: Exp. Mol. Pathol., 17: 206, 1972.

    Article  CAS  PubMed  Google Scholar 

  71. Burch, G. E., Tsui, C. Y., Harb, J. M., and Colcolough, H. L.: Arch. Int. Med., 128: 40, 1971.

    Article  CAS  Google Scholar 

  72. Burch, G. E., Tsui, C. Y., and Harb, J. M.: Experientia, 28: 310, 1972.

    Article  CAS  PubMed  Google Scholar 

  73. Webb, S. R., Loria, R. M., Madge, G. E., and Kibrick, S.: J. Exp. Med., 143: 1239, 1976.

    Article  CAS  PubMed  Google Scholar 

  74. Coleman, T. J., Taylor, K. W., and Gamble, D. R.: Diabetologia, 10: 755, 1974.

    Article  CAS  PubMed  Google Scholar 

  75. Ross, M. E., and Notkins, A. L.: Brit. Med. J., 2: 226, 1974.

    Article  CAS  PubMed  Google Scholar 

  76. Personal communications from R. Louria.

    Google Scholar 

  77. Kundin, W. D., Liu, C., and Rodina, P.: J. Immunol., 96: 39, 1966.

    CAS  PubMed  Google Scholar 

  78. Jahrling, P. B., and Scherer, W. F.: Amer. J. Pathol. 72: 25, 1973.

    CAS  Google Scholar 

  79. Gorelkin, L. and Jahrling, P. B.: Amer. J. Pathol., 75: 349, 1974.

    CAS  Google Scholar 

  80. Rodriguez, G.: Patologia, 13: 297, 1975.

    Google Scholar 

  81. Rayfield, E. J., Jahrling, P. B., Gorelkin, I.., and Curnow, R. T.: Diabetes, 23: 345, 1974.

    Google Scholar 

  82. Rayfield, E. J., Gorelkin, I.., Curnow, R. T., and Jahrling, P. B.: Diabetes, 1977 (in press).

    Google Scholar 

  83. Smith, M. G., and Vellios, F.: Arch. Pathol., 50: 862, 1950.

    CAS  Google Scholar 

  84. Worth, W. A., and Howard, H. I..: Amer. J. Pathol. 26: 17, 1950.

    Google Scholar 

  85. Wyatt, J. P., Saxton, J., Lee, R. S., and Pinkerton, H.: J. Pediat., 36: 271, 1950.

    Article  CAS  PubMed  Google Scholar 

  86. Kissane, J. M., and Smith, M. G.: Pathology of Infancy and Childhood. C. V. Mosby, St. Louis, 1967, p. 92.

    Google Scholar 

  87. Craighead, J. E.: Prog. Med. Virol., 19: 161, 1975.

    CAS  PubMed  Google Scholar 

  88. Hultquist, G., Nordvall, S., and Sundstrom, C.: Upsal. J. Med. Sci., 78: 139, 1973.

    Article  CAS  Google Scholar 

  89. Gepts, W.: Personal communication.

    Google Scholar 

  90. Brody, A. R., and Craighead, J. E.: J. Infect. Dis., 129: 677, 1971.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1977 Plenum Press, New York

About this chapter

Cite this chapter

Craighead, J.E. (1977). Viral Diabetes. In: Volk, B.W., Wellmann, K.F. (eds) The Diabetic Pancreas. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2325-9_19

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-2325-9_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2327-3

  • Online ISBN: 978-1-4684-2325-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics