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Cancer and Diabetes

  • Chapter
The Diabetic Pancreas

Abstract

The relationship of cancer and diabetes has been discussed for many years. Despite the large number of studies which have been carried out over the years, no unanimity of opinion has been expressed. Some investigators believed that cancer occurs more frequently in diabetics than in nondiabetic persons, with an incidence ranging from 3 to 10%.1–4 Others,5–7 using different figures, arrived at the conclusion that no association between these diseases exists. In 1934, Marble5 studied the records of 10,000 patients with proven diabetes. Among these 256 (2.56%) had malignant disease. He also investigated the figures of insurance companies and felt that although certain evidence suggested that cancer was more common among diabetic individuals, it was not possible to draw any definite conclusions. In a study of associated causes of death of persons dying of cancer, in Massachusetts, during a 10-year period, Wilson and Maher1 noted that diabetes and cancer occur together much more frequently than would be expected if the two diseases were independently studied. Ellinger and Landsman,2 in a survey of 1280 diabetic patients seen at the Montefiore Hospital in New York City from 1933 to 1941, found 39 (3.04%) afflicted with malignant disease. This incidence of cancer was 6.5 times greater than that in the general population (0.46%) in the State of New York in 1941. Jacobson,3 using data from certificates and matched hospital case histories in New York, concluded that cancer is more common among diabetics than nondiabetics.

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References

  1. Wilson, E. B., and Maher, H. C.: Amer. J. Cancer, 16:227, 1932.

    Google Scholar 

  2. Ellinger, F., and Landsman, H.: N.Y. J. Med., 44:259, 1944.

    Google Scholar 

  3. Jacobson, P. H.: Millbank Mem. Fund. Quart., 26:90, 1948.

    Article  CAS  Google Scholar 

  4. Warren, S., and LeCompte, P. M.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1952, p. 268.

    Google Scholar 

  5. Marble, A.: N. Engl. J. Med., 211:339, 1934.

    Article  Google Scholar 

  6. Seifert, G., and Eichler, R.: Ztschr. Krebsforsch., 60:200, 1954.

    Article  CAS  Google Scholar 

  7. Ferner, W.: Ztschr. Krebsforsch., 60:399, 1955.

    Article  Google Scholar 

  8. Herdan, G.: Brit. J. Cancer, 14:449, 1960.

    Article  PubMed  CAS  Google Scholar 

  9. Aronson, S. M., Aronson, B. E., Okasaki, H., and Browder, E. J.: Tr. Amer. Neurol. Assoc., 84:155, 1959.

    CAS  Google Scholar 

  10. Joslin, E. P., Lombard, H. L., Burrows, R. E., and Manning, M. D.: N. Engl. J. Med., 260:486, 1959.

    Article  PubMed  CAS  Google Scholar 

  11. Steele, J. M., and Sperling, W. L.: Guthrie Clin. Bull., 30:63, 1961.

    Google Scholar 

  12. Warren, S., LeCompte, P. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1966, p. 435.

    Google Scholar 

  13. Marble, A., and Ramos, E.: In: Joslin’s Diabetes Mellitus. Edited by A. Marble, P. White, R. Bradley, and L. P. Krall. Lea & Febiger, Philadelphia, 1971, p. 696.

    Google Scholar 

  14. Freund, E.: Wien. Med. Bull., 8:268, 1885.

    Google Scholar 

  15. Marks, P. A., and Bishop, J.: Proc. Amer. Assoc. Cancer Res., 2:131, 1956.

    Google Scholar 

  16. Lisker, S. A., Brody, J. I., and Beizer, L. H.: Amer. J. Med. Sci., 252:282, 1966.

    Article  PubMed  CAS  Google Scholar 

  17. Edmonson, J. H.: Cancer, 19:277, 1966.

    Article  PubMed  CAS  Google Scholar 

  18. Glicksman, A. S., and Rawson, R. W.: Cancer, 9:1127, 1956.

    Article  PubMed  CAS  Google Scholar 

  19. Glicksman, A. S., Myers, W. P. L., and Rawson, R. W.: Med. Clin. N. Amer., 40:887, 1956.

    PubMed  CAS  Google Scholar 

  20. Benjamin, F., and Romney, S.: Cancer, 17:386, 1964.

    Article  PubMed  CAS  Google Scholar 

  21. Benjamin, F., and Casper, D. J.: Amer. J. Obstet. Gynecol., 94:991, 1966.

    CAS  Google Scholar 

  22. Lynch, H. T., Krush, A. J., Larsen, A. L., and Magnuson, C. W.: Amer. J. Med. Sci., 252:381, 1966.

    Article  PubMed  CAS  Google Scholar 

  23. Streeten, D. H. P., Berstein, M. M., Marmor, B. M., and Doisy, R. J.: Diabetes, 14:579, 1965.

    PubMed  CAS  Google Scholar 

  24. Crockford, P. M., Harbeck, R. J., and Williams, R. H.: Lancet, 1:465, 1966.

    Article  PubMed  CAS  Google Scholar 

  25. Balodimos, M. C., Balodimos, P. M., Davis, C. B., Belleau, R., Joshi, P. C., and Kusakcioglu, O.: Geriatrics, 22:159, 1967.

    PubMed  CAS  Google Scholar 

  26. Weisenfeld, S., Hecht, A., and Goldner, M. G.: Cancer, 15:18, 1962.

    Article  PubMed  CAS  Google Scholar 

  27. Mirallié, C.: Gaz. Hôp., 66:889, 1893.

    Google Scholar 

  28. Eusterman, G. B.: Tr. Amer. Gastroenterol. Assoc., 25:126, 1922.

    Google Scholar 

  29. Friedenwald, J., and Cullen, T. S.: Amer. J. Med. Sci., 176:31, 1928.

    Article  Google Scholar 

  30. Ranson, H. K.: Amer. J. Surg., 40:264, 1938.

    Article  Google Scholar 

  31. Franco, S. C.: Amer. J. Digest. Dis., 8:65, 1941.

    Article  Google Scholar 

  32. Kiefer, E. D., and Moravec, M.: S. Clin. North. Amer., 23:738, 1943.

    Google Scholar 

  33. Arkin, A., and Weisberg, S. W.: Gastroenterology, 13:118, 1949.

    PubMed  CAS  Google Scholar 

  34. Elman, R., and Butcher, H. R.: Gastroenterology, 13:285, 1949.

    PubMed  CAS  Google Scholar 

  35. Broadbent, T. R., and Kerman, H. D.: Gastroenterology, 17:163, 1951.

    PubMed  CAS  Google Scholar 

  36. Brown, R. K., Moseley, V., Pratt, T. D., and Pratt, J. H.: Amer. J. Med. Sci., 223:349, 1952.

    Article  PubMed  CAS  Google Scholar 

  37. Smith, B. K., and Albright, E. C.: Ann. Int. Med., 36:90, 1952.

    Google Scholar 

  38. Country, J. C., and Foulk, R.: U.S. Armed Forces Med. J., 4:831, 1953.

    PubMed  CAS  Google Scholar 

  39. McKittrick, L. S., and Root, H. F.: Diabetic Surgery. Lea & Febiger, Philadelphia, 1928, p. 250.

    Google Scholar 

  40. Dashiell, G. F., and Palmer, W. L.: Arch. Int. Med., 81:173, 1948.

    Article  CAS  Google Scholar 

  41. levy, H., and Lichtman, S. S.: Arch. Int. Med., 65:607, 1940.

    Article  Google Scholar 

  42. Arry, M., Pallard, P., and Vadron, A.: Rev. Lyon Méd., 12:859, 1963.

    Google Scholar 

  43. Bell, E. T.: Amer. J. Pathol., 33:499, 1957.

    CAS  Google Scholar 

  44. Clark, C. G., and Mitchell, P. E. G.: Brit. Med. J., 2:1259, 1961.

    Article  PubMed  CAS  Google Scholar 

  45. Murphy, R., and Smith, F. H.: Med. Clin. North Amer., 47:397, 1963.

    CAS  Google Scholar 

  46. Salmon, P. A.: Surgery, 60:554, 1966.

    PubMed  CAS  Google Scholar 

  47. Schlesinger, F. G., Schwarz, F., and Wagenvoort, C. A.: Acta Med. Scand., 166:337, 1960.

    Article  PubMed  CAS  Google Scholar 

  48. Green, R. C., Jr., Baggenstoss, A. H., and Sprague, R. G.: Diabetes, 7:308, 1960.

    Google Scholar 

  49. Silver, G. B., and Lubliner, R. K.: Surg., Gynecol. Obstet., 86:703, 1948.

    CAS  Google Scholar 

  50. Gullick, H. D.: Medicine, 38:47, 1959.

    PubMed  CAS  Google Scholar 

  51. Berk, J. E.: Arch. Int. Med., 68:525, 1941.

    Article  Google Scholar 

  52. Marble, A.: In: The Treatment of Diabetes Mellitus. Edited by E. P. Joslin, H. F. Root, P. White, and A. Marble. Lea & Febiger, Philadelphia, 1959, p. 328.

    Google Scholar 

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Author information

Author notes

  1. Bruno W. Volk

    Present address: University of California, Irvine, California, USA

  2. Klaus F. Wellmann

    Present address: Beekman Downtown Hospital, New York, New York, USA

Authors and Affiliations

  1. Isaac Albert Research Institute of the Kingsbrook Jewish Medical Center and, Downstate Medical Center, State University of New York, Brooklyn, New York, USA

    Bruno W. Volk & Klaus F. Wellmann

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  1. Bruno W. Volk
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  2. Klaus F. Wellmann
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Editor information

Editors and Affiliations

  1. Isaac Albert Research Institute, Brooklyn, New York, USA

    Bruno W. Volk  & Klaus F. Wellmann  & 

  2. University of California, Irvine, California, USA

    Bruno W. Volk

  3. Beekman Downtown Hospital, New York, USA

    Klaus F. Wellmann

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© 1977 Plenum Press, New York

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Volk, B.W., Wellmann, K.F. (1977). Cancer and Diabetes. In: Volk, B.W., Wellmann, K.F. (eds) The Diabetic Pancreas. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2325-9_13

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  • DOI: https://doi.org/10.1007/978-1-4684-2325-9_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2327-3

  • Online ISBN: 978-1-4684-2325-9

  • eBook Packages: Springer Book Archive

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