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Heat Production and Temperature Regulation

  • Chapter
Perinatal Physiology

Abstract

Heat production is a side product of metabolic processes, the continuous occurrence of which provides the energy basis of life. This heat production necessarily increases the temperature of an organism above that of the environment. In the majority of the members of the animal kingdom, the metabolic rate does not allow an increase in body temperature of more than some 1/10 of a degree (bradymetabolism). In all these animals, body temperature shows wide fluctuations that depend on changes in the environmental temperature; they are therefore called Poikilothermic animals.

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References

  1. Abrams, R., Caton, D., Clapp, J., and Barron, D. H., 1970, Thermal and metabolic features of life in utero, Clin. Obstet. Gynecol. 13:549–564.

    Article  CAS  Google Scholar 

  2. Adamsons, K., Jr., Gandy, G. M., and James, L. S., 1965, The influence of thermal factors upon oxygen consumption of the newborn human infant, J. Pediatr. 66:495–508.

    Article  Google Scholar 

  3. Adolph, E. F., 1951, Responses to hypothermia in several species of infant mammals, Amer. J. Physiol. 166:75–91.

    PubMed  CAS  Google Scholar 

  4. Adolph, E. F., 1956, General and specific characteristics of physiological adaptations, Amer. J. Physiol. 184:18–28.

    PubMed  CAS  Google Scholar 

  5. Adolph, E. F., 1964, Perspectives of adaptation: Some general properties, in: Handbook of Physiology (D. B. Dill, ed.), Sect. 4, pp. 27–35, American Physiological Society, Washington, D. C.

    Google Scholar 

  6. Adolph, E. F., 1968, Origins of Physiological Regulations, Academic Press, New York and London.

    Google Scholar 

  7. Adolph, E. F., and Molnar, G. W., 1946, Exchanges of heat and tolerances to cold in men exposed to outdoor weather, Amer. J. Physiol. 146:507–537.

    PubMed  CAS  Google Scholar 

  8. Agate, F. J., and Silverman, W. A., 1963, The control of body temperature in the small newborn infant by low energy infrared radiation, Pediatrics 31:725–733.

    PubMed  Google Scholar 

  9. Aherne, W., and Hull, D., 1964, The site of heat production in the newborn infant, Proc. R. Soc. Med. 57:1172, 1173.

    Google Scholar 

  10. Alexander, G., 1961, Temperature regulation in the newborn lamb. III. Effect of environmental temperature on metabolic rate, body temperatures and respiratory quotient, Aust. J. Agric. Res. 12: 1152–1174.

    Article  Google Scholar 

  11. Alexander, G., 1962, Temperature regulation in the newborn lamb. V. Summit metabolism, Aust. J. Agric. Res. 13(1): 100–121.

    Article  Google Scholar 

  12. Alexander, G., 1975, Body temperature control in mammalian young, Br. Med. Bull. 31:62–68.

    PubMed  CAS  Google Scholar 

  13. Andjus, R.K., and Smith, A. U., 1955, Reanimation of adult rats from body temperatures between 0 and + 2°C, J. Physiol. 128:446–472.

    PubMed  CAS  Google Scholar 

  14. Andrews, J. F., Mercer, J. B., Ryan, E. M., and Székely, M., 1973, Metabolic changes in the lamb during the first 36 hr of life related to body weight and to environmental temperature, J. Physiol. 236:35, 36.

    Google Scholar 

  15. Andrews, J. F., Mercer, J. B., Ryan, E. M., and Székely, M., 1975, The post-natal increase in minimum metabolic rate in the lamb, in: Depressed Metabolism and Cold Thermogenesis (L. Jansky, ed.), Charles University, Prague.

    Google Scholar 

  16. Aschoff, J., and Kramer, 1971, Temperature-regulation, in: Physiologie des Menschen, Vol. 2, Energiehaushalt und Temperaturregulation (Gauer, Kramer, and Jung, eds.), Urban and Schwarzenberg, Munich.

    Google Scholar 

  17. Bargmann, W., von Hehn, G., and Lindner, E., 1968, Über die Zellen des braunen Fettgewebes und ihre Innervation, Z. Zellforsch. 85:601–613.

    Article  PubMed  CAS  Google Scholar 

  18. Behmann, F. W., and Bontke, E., 1958, Die Regelung der Wärmebildung bei künstlicher Hypothermie. I. Experimentelle Untersuchungen über den Einfluss der Narkosetiefe, Pflügers. Arch. ges. Physiol. 266:408–421.

    Article  CAS  Google Scholar 

  19. Behnke, A. R., and Yaglou, C. P., 1951, Physiological responses of men to chilling in ice water and to slow and fast rewarming, J. Appl. Physiol. 3:591–602.

    PubMed  CAS  Google Scholar 

  20. Benedict, F. G., and Talbot, F. B., 1915, The Physiology of the Newborn Infant: Character and Amount of the Catabolism, Carnegie Institution of Washington Publication No. 233, Washington D.C.

    Google Scholar 

  21. Benzinger, T. H., 1964, The thermal homeostasis of man, Symp. Soc. Exp. Biol. 18:49–80.

    PubMed  CAS  Google Scholar 

  22. Benzinger, T. H., and Kitzing, C., 1963, Gradient layer calorimetry and human calorimetry, in: Temperature—Its Measurement and Control in Science and Industry, Vol. 3, Part 3, pp. 87–109, Reinhold Publishing Corp., New York.

    Google Scholar 

  23. Bianca, W., 1970, Animal response to meteorological stress as a function of age, Int. J. Biometeorol. Suppl. 14:119–131.

    Google Scholar 

  24. Bianca, W., and Hales, J. R. S., 1970, Sweating, panting and body temperatures of newborn and one-year-old calves at high environmental temperatures, Br. Vet. J. 126:45–52.

    PubMed  CAS  Google Scholar 

  25. Blatteis, C. M., 1971, Shivering and nonshivering thermogenesis during hypoxia, in: Proceedings of the International Symposium on Environmental Physiology, Dublin, 1971, pp. 151–160, Federation of American Societies for Experimental Biology.

    Google Scholar 

  26. Blatteis, C. M., 1975, Postnatal development of pyrogenic sensitivity in guinea pigs, J. Appl. Physiol. 39:251–257.

    PubMed  CAS  Google Scholar 

  27. Blatteis, C. M., 1976, Effect of propranolol on endotoxin-induced pyrogenesis in newborn and adult guinea pigs, J. Appl. Physiol. 40:35–39.

    PubMed  CAS  Google Scholar 

  28. Blatteis, C. M., 1976, A possible cause of the pyrogenic insensitivity of neonates to endotoxin, Fed. Proc. Fed. Amer. Soc. Exp. Biol. 35:(3):482, abstract of a paper presented at the 60th Physiological congress, Anaheim, California, April 11–16, 1976. (Full-length article: Comparison of endotoxin and leukocyte pyrogenicity in newborn guinea pigs, J. Appl. Physiol. 42:355–361, 1977.)

    Google Scholar 

  29. Bligh, J., 1973, Temperature Regulation in Mammals and Other Vertebrates, North-Holland Publishing Co., Amsterdam and London; American Elsevier Publishing Co., New York.

    Google Scholar 

  30. Bligh, J., and Johnson, K. G., 1973, Glossary of terms for thermal physiology, J. Appl. Physiol. 35:941–961.

    PubMed  CAS  Google Scholar 

  31. Brown, A. C., and Brengelmann, G. L., 1970, The temperature regulation control system, in: Physiological and Behavioral Temperature Regulation (J. D. Hardy, A. P. Gagge, and J. A. J. Stolwijk, eds.), Charles C. Thomas, Springfield, Illinois.

    Google Scholar 

  32. Brück, K., 1961, Temperature regulation in the newborn infant, Biol. Neonate 3:65–119.

    Article  Google Scholar 

  33. Brück, K., 1964, General aspects of temperature regulation of small subjects, in: The Adaptation of the Newborn Infant to Extra-uterine Life (J. H. P. Jonxis, H. D. A. Visser, and J. A. Troelstra, eds.), pp. 229–247, H. E. Stenfert Kroese, Leiden, South Holland.

    Google Scholar 

  34. Brück, K., 1968, Which environmental temperature does the premature infant prefer?, Pediatrics 41: 1027–1030.

    PubMed  Google Scholar 

  35. Brück, K., 1970, Non-shivering thermogenesis and brown adipose tissue in relation to age, and their integration in the thermoregulatory system, in: Brown Adipose Tissue (O. Lindberg, ed.), American Elsevier Publishing Co., New York.

    Google Scholar 

  36. Brück, K., 1970, Heat production and temperature regulation, in: Physiology of the Perinatal Period, Vol. I (U. Stave, ed.), Appleton-Century-Crofts, New York.

    Google Scholar 

  37. Brück, K., 1976, Cold adaptation in man, in: Regulation of Depressed Metabolism and Thermogenesis (L. Jansky and X. J. Mussacchia, eds.), Charles C. Thomas, Springfield, Illinois.

    Google Scholar 

  38. Brück, K., 1976, Temperature regulation and catecholamines, Isr. J. Med. Sci. 12(9):924–933.

    PubMed  Google Scholar 

  39. Brück, K., and Brück, M., 1960, Der Energieumsatz hypothermer Frühgeborener, Klin. Wochenschr. 38: 1125–1130.

    Article  Google Scholar 

  40. Brück, K., and Schwennicke, H. P., 1971, Interaction of superficial and hypothalamic thermosensitive structures in the control of nonshivering thermogenesis, Int. J. Biometeorol. 15:156.

    Article  PubMed  Google Scholar 

  41. Brück, K., and Wünnenberg, B., 1965, Über die Modi der Thermogenese beim neugeborenen Warmblüter. Untersuchungen am Meerschweinchen, Pflügers. Arch. ges. Physiol. 282:362–375.

    Article  Google Scholar 

  42. Brück, K., and Wünnenberg, B., 1965, Blockade der chemischen Thermogenese und Auslösung von Muskelzittern durch Adrenolytica und Ganglienblockade beim neugeborenen Meerschweinchen, Pflügers.. Arch. ges. Physiol. 282:376–389.

    Article  Google Scholar 

  43. Brück, K., and Wünnenberg, B., 1965, Untersuchungen über die Bedeutung des multiloculären Fettgewebes für die Thermogenese des neugeborenen Meerschweinchens, Pflügers.. Arch. ges. Physiol. 283: 1–16.

    Article  Google Scholar 

  44. Brück, K., and Wünnenberg, B., 1966, The influence of ambient temperature in the process of replacement of non-shivering by shivering thermogenesis during postnatal development, Fed. Proc. Fed. Amer. Soc. Exp. Biol. 25:1332–1336.

    Google Scholar 

  45. Brück, K., and Wünnenberg, W., 1966, Beziehung zwischen Thermogeneses im “braunen” Fettgewebe, Temperatur im cervicalen Anteil des Vertebralkanals und Kältezittern, Pflügers.. Arch. ges. Physiol. 290: 167–183.

    Article  Google Scholar 

  46. Brück, K., and Wünnenberg, W., 1967, Eine kälteadaptative Modifikation: Senkung der Schwellentemperaturen für Kältezittern, Pflügers.. Arch. ges. Physiol. 293:226–235.

    Article  Google Scholar 

  47. Brück, K., and Wünnenberg, W., 1970, Meshed control of two effector systems: Non-shivering and shivering thermogenesis, in: Physiological and Behavioral Temperature Regulation (J. D. Hardy, A. P. Gagge, and J. A. J. Stolwijk, eds.), Charles C. Thomas, Springfield, Illinois.

    Google Scholar 

  48. Brück, K., Baum, E., and Schwennicke, H. P., 1976, Cold adaptive modifications in man induced by repeated short-term cold-exposures and during a 10-day and -night cold-exposure, Pflügers.. Arch. ges. Physiol. 363:125–133.

    Article  Google Scholar 

  49. Brück, K., Brück, M., and Lemtis, H., 1957, Hautdurchblutung und Thermoregulation bei neugeborenen Kindern, Pflügers.. Arch. ges. Physiol. 265:55–65.

    Article  Google Scholar 

  50. Brück, Type="SmallCaps">K., Brück,M., and Lemtis,H., 1958,Thermoregulatorische Veränderungen des Energies-toffwechsels bei reifen Neugeborenen, Pflügers. Arch. ges. Physiol. 267:382–391.

    Article  Google Scholar 

  51. Brück, K., Brück, M., and Lemtis, H., 1960, Die Temperaturregelung Neugeborener und Frühgeborener nach spontaner und pathologischer Geburt, Geburtshilfe Frauenheilkd. 20:461–472.

    Google Scholar 

  52. Brück, K., Parmelee, A. H., and Brück, M., 1962, Neutral temperature range and range of “thermal comfort” in premature infants, Biol. Neonate 4:32–51.

    Article  Google Scholar 

  53. Brück, K., Wünnenberg, W., Gallmeier, H., and Ziehm, B., 1970, Shift of threshold temperature for shivering and heat polypnea as a mode of thermal adaptation, Pflügers. Arch. ges. Physiol. 321:159–172.

    Article  Google Scholar 

  54. Brück, K., Wünnenberg, W., and Zeisberger, E., 1969, Comparison of cold-adaptive metabolic modifications in different species with special reference to the miniature pig, Fed. Proc. Fed. Amer. Soc. Exp. Biol. 28:1035–1041.

    Google Scholar 

  55. Burton, A. C., and Edholm, O. G., 1969,Type="Italic">Man in a Cold Environment, Hafner Publishing Co., New York and London.

    Google Scholar 

  56. Buetow, K. C., and Klein, S. W., 1964, Effect of maintenance of “normal” skin temperature on survival of infants of low body weights, Pediatrics 34:163–170.

    PubMed  CAS  Google Scholar 

  57. Celander, O., 1960, Blood flow in the foot and calf of the newborn, Acta Paediatr. Scand. 49:488–496.

    Article  CAS  Google Scholar 

  58. Clapp, J. F., and Abrams, R. M., 1976, The post-partum chill, Isr. J. Med. Sci. 12:1131–1133.

    PubMed  Google Scholar 

  59. Cooper, K. E., 1970, Studies of the human central warm receptor, in: Physiological and Behavioral Temperature Regulation (J. D. Hardy, A. P. Gagge, and J. A. J. Stolwijk, eds.), Charles C. Thomas, Springfield, Illinois.

    Google Scholar 

  60. Cooper, K. E., Pittman, Q. J., and Veale, W. L., 1975, Observations on the development of the “fever” mechanism in the fetus and newborn. Temperature regulation and drug action, in: Proceedingsof a Symposium, Paris 1974, pp. 43–50, S. Karger, Basel.

    Google Scholar 

  61. Cort, J. H., and McCance, R. A., 1953, The neural control of shivering in the pig, J. Physiol. (London) 120:115–121.

    CAS  Google Scholar 

  62. Crenshaw, C., Huckabee, W. E., Curet, L. B., Mann, L., Barron, D. H., 1968, A method for the estimation of the umbilical blood flow in unstressed sheep and goats with some results on its application, J. Exp. Physiol. 53:65–75.

    CAS  Google Scholar 

  63. Dawes, G. S., 1968, Foetal and Neonatal Physiology, Year Book Medical Publishers, Chicago.

    Google Scholar 

  64. Dawes, G. S., and Mott, J. C., 1959, The increase in oxygen consumption of the lamb after birth, J. Physiol. (London) 146:295–315.

    CAS  Google Scholar 

  65. Dawes, G. S., Jacobson, H. N., Mott, C., and Shelley, H. J., 1960, Some observations of foetal and newborn rhesus monkeys, J. Physiol. (London) 152:271–298.

    CAS  Google Scholar 

  66. Dawkins, M. J. R., and Hull, D., 1964, Brown adipose tissue and the response of the newborn rabbit to cold, J. Physiol. (London) 172:216–238.

    CAS  Google Scholar 

  67. Dawkins, M. J. R., and Scopes, J. W., 1965, Non-shivering thermogenesis and brown adipose tissue in the human newborn infant, Nature (London) 206:201, 202.

    Google Scholar 

  68. Day, R. L., Caliguiri, L., Kamenski, C., and Ehrlich, F., 1964, Body temperature and survival of premature infants, Pediatrics 34:171–181.

    PubMed  CAS  Google Scholar 

  69. Day, R. L., Curtis, J., and Kelley, M., 1943, Respiratory metabolism in infancy and in childhood. XXVII. Regulation of body temperature of premature infants, Amer. J. Dis. Child. 65:376–398.

    Google Scholar 

  70. Documenta Geigy, 1960, Wissenschaftliche Tabellen (J. R. Geigy, ed.), J. R. Geigy, Basel.

    Google Scholar 

  71. Doerr, F. F., and Heite, H. J., 1957, Farbe und Wärmeabgabe der Haut nach Einwirkung von Nikotinsäurebenzylester insbesondere bei Neuroder-mitikern, Arch. Klin. Exp. Dermatol. 204:543–553.

    Article  PubMed  CAS  Google Scholar 

  72. Donhoffer, S., 1966, The regulation of energy metabolism and van’t Hoff’s rule in the homeotherm animal, Helgol. Wiss. Meeresunters. 14:541–558.

    Article  Google Scholar 

  73. Ebbecke, U., 1917, Die lokale vasomotorische Reaktion (L.V.R.) der Haut und der inneren Organe, Pflügers. Arch. ges. Physiol. 169:1–81.

    Article  Google Scholar 

  74. Eckert, E., 1959, Wärme- und Stoffaustausch, 2d Ed., Springer-Verlag, Berlin.

    Google Scholar 

  75. Fanger, P. O., 1972, Thermal Comfort. Analysis and Applications in Environmental Engineering, McGraw-Hill Book Co., New York.

    Google Scholar 

  76. Fisher, D. A., and Dussault, J. H., 1974, Development of the mammalian thyroid gland, in: Handbook of Physiology (R. O. Greep and E. B. Astwood, eds.), Sect. 7, pp. 21–38, American Physiological Society, Washington, D.C.

    Google Scholar 

  77. Foster, K. G., Hey, E. N., and Katz, G., 1969, The response of the sweat glands of the new-born baby to thermal stimuli and to intradermal acetylcholine, J. Physiol. (London) 203:13–29.

    CAS  Google Scholar 

  78. Freund, H., and Jansen, S., 1923, Über den Sauerstoffverbrauch der Skelettmuskulatur und seine Abhängigkeit von der Wärmeregulation, Pflügers. Arch. ges. Physiol. 200:96–118.

    Article  CAS  Google Scholar 

  79. Friis-Hansen, B., 1959, Changes in body water compartments during growth, in: Die physiologische Entwicklung des Kindes (F. Linneweh, ed.), pp. 196–203, Springer-Verlag, Berlin.

    Google Scholar 

  80. Gagge, A. P., Hardy, J. D., and Rapp, G. M., 1969, Proposed standard system of symbols for thermal physiology, J. Appl. Physiol. 27:439–446.

    Google Scholar 

  81. Gandy, G. M., Adamsons, K., Jr., Cunningham, N., Silverman, W. A., and James, L. S., 1964, Thermal environments and acid-base homeostatis in human infants during the first few hours of life, J. Clin. Invest. 43:751–758.

    Article  PubMed  CAS  Google Scholar 

  82. Gelineo, S., 1957, Développement ontogénétique de la thermorégulation chez le chien, Bull. Acad. Serbe Sci. 18:97–102.

    Google Scholar 

  83. Gelineo, S., and Sokic, P., 1953, La naissance et le développement de la thermorégulation chimique chez lespermophile (Citellus citellus), Bull. Acad. Serbe Sci. 12:1–11.

    Google Scholar 

  84. Glass, L., Silverman, W. A., and Sinclair, J. C., 1968, Effect of the thermal environment on cold resistance and growth of small infants after the first week of life, Pediatrics 41:1033–1046.

    PubMed  CAS  Google Scholar 

  85. Golenhofen, K., Hensel, H., and Hildebrandt, G., 1963, Durchblutungsmessung mit Wärmeleitelementen, Verlag Georg Thieme, Stuttgart.

    Google Scholar 

  86. Grad, B., 1953, Changes in oxygen consumption and heart rates of rats during growth and ageing: Role of the thyroid gland, Amer. J. Physiol. 174:481–486.

    PubMed  CAS  Google Scholar 

  87. Haddad, H. M., 1960, Studies on thyroid hormone metabolism in children, Pediatrics 57:391–398.

    Article  CAS  Google Scholar 

  88. Hahn, P., and Novak, M., 1975, Development of brown and white adipose tissue, J. Lipid Res. 16:79–91.

    PubMed  CAS  Google Scholar 

  89. Hardy, J. D., 1961, Physiology of temperature regulation, Physiol. Rev. 41:521–606.

    PubMed  CAS  Google Scholar 

  90. Hardy, J. D., Gagge, P. A., and Stolwijk, J. A. J. (eds.), 1970, Physiological and BehavioralTemperature Regulation, Charles C. Thomas, Springfield, Illinois.

    Google Scholar 

  91. Hart, J. S., Héroux, O., and Dépocas, F., 1956, Cold acclimation and the electromyogram of unanesthetized rats, J. Appl. Physiol. 9:404–408.

    PubMed  CAS  Google Scholar 

  92. Heim, T., and Hull, D., 1966, The blood flow and oxygen consumption of brown adipose tissue in the newborn rabbit, J. Physiol. (London) 186:42–55.

    CAS  Google Scholar 

  93. Heim, T., and Hull, D., 1966, The effect of propranolol on the calorigenic response in brown adipose tissue of newborn rabbits to catecholamines, glucagon, corticotrophin and cold exposure, J. Physiol. (London) 187:271–283.

    CAS  Google Scholar 

  94. Heldmaier, G., 1971, Zitterfreie Wärmebildung und Körpergrösse bei Säugetieren, Z, Vgl. Physiol. 73:222–248.

    Article  Google Scholar 

  95. Hellbrügge, T., 1960, The development of circadian rhythms in infants, Cold Spring Harbor Symp. Quant. Biol. 25:311.

    Article  Google Scholar 

  96. Hellon, R. F., 1970, Hypothalamic neurons responding to changes in hypothalamic and ambient temperatures, in: Physiological and Behavioral Temperature Regulation, (J. D. Hardy, A. P. Gagge, and J. A. J. Stolwijk, eds.), Charles C. Thomas, Springfield, Illinois.

    Google Scholar 

  97. Hemingway, A., 1963, Shivering, Physiol. Rev. 43:397–422.

    PubMed  CAS  Google Scholar 

  98. Hensel, H., Brück, K., and Raths, P., 1973, Homeothermic organisms, in: Temperature and Life (H. Precht, J. Christophersen, H. Hensel, and W. Larcher, eds.), Springer-Verlag, Berlin-Heidelberg-New York.

    Google Scholar 

  99. Héroux, O., 1955, Acclimination of adrenalec-tomized rats to low environmental temperature, Amer. J. Physiol. 181:75–78.

    PubMed  Google Scholar 

  100. Hey, E. N., 1968, Small globe thermometers, J. Sci. Instrum. Ser. 2 1:955–957, 1260.

    Google Scholar 

  101. Hey, E. N., 1969, The relation between environmental temperature and oxygen consumption in the new-born baby, J. Physiol. (London) 200:589–603.

    CAS  Google Scholar 

  102. Hey, E. N., 1972, Thermal regulation in the newborn, Br. J. Hosp. Med., July, pp. 51–64.

    Google Scholar 

  103. Hey, E. N., 1974, Physiological control over body temperature, in: Heat Loss from Animals and Man (J. L. Monteith and L. E. Mount, eds.), Butterworths, London.

    Google Scholar 

  104. Hey, E. N., 1975, Thermal neutrality, Br. Med. Bull. 31:69–74.

    PubMed  CAS  Google Scholar 

  105. Hey, E. N., and Katz, G., 1969, Temporary loss of a metabolic response to cold stress in infants of low birth weight, Arch. Dis. Child. 44:323.

    Article  PubMed  CAS  Google Scholar 

  106. Hey, E. N., and Katz, G., 1969, Evaporative water loss in the new-born baby, J. Physiol. (London) 200:605–619.

    CAS  Google Scholar 

  107. Hey, E. N., and Katz, G., 1970, The range of thermal insulation in the tissues of the newborn baby, J. Physiol. (London) 207:667–681.

    CAS  Google Scholar 

  108. Hey, E. N., and Katz, G., 1970, The optimum thermal environment for naked babies, Arch. Dis. Child. 45:328–334.

    Article  PubMed  CAS  Google Scholar 

  109. Hey, E. N., and Mount, L. E., 1967, Heat losses from babies in incubators, Arch. Dis. Child. 42:75–84.

    Article  PubMed  CAS  Google Scholar 

  110. Hey, E. N., Katz, G., and O’Connell, B., 1970, The total thermal insulation of the newborn baby, J. Physiol. (London) 207:683–698.

    CAS  Google Scholar 

  111. Hill, J. R., 1959, The oxygen consumption of newborn and adult mammals: Its dependence on the oxygen tension in the inspired air and on the environmental temperature, J. Physiol. (London) 149:346.

    CAS  Google Scholar 

  112. Hill, J. R., and Rahimtulla, K. A., 1965, Heat balance and the metabolic rate of newborn babies in relation to environmental temperature, and the effect of age and of weight on basal metabolic rate, J. Physiol. (London) 180:239–265.

    CAS  Google Scholar 

  113. Hill, J. R., and Robinson, D. C., 1968, Oxygen consumption in normally grown, small-for-dates and large-for-dates new-born infants, J. Physiol. (London) 199:685–703.

    CAS  Google Scholar 

  114. Himms-Hagen, J., 1967, Sympathetic regulation of metabolism, Pharmacol. Rev. 19:367–461.

    PubMed  CAS  Google Scholar 

  115. Hissa, R., 1968, Postnatal development of thermoregulation in the Norwegian lemming and the golden hamster, Ann. Zool. 5:345–383.

    Google Scholar 

  116. Horwitz, B. A., 1975, Pathways underlying nonshivering thermogenesis in peripheral tissues, in: Proceedings of an International Symposium on Depressed Metabolism and Cold Thermogenesis, Prague (L. Jansky, ed.), pp. 127–132, Charles University, Prague.

    Google Scholar 

  117. Hsieh, A. C. L., Carlson, L. D., and Gray, G., 1957, Role of the sympathetic nervous system in the control of chemical regulation of heat production, Amer. J. Physiol. 190:247–251.

    PubMed  CAS  Google Scholar 

  118. Hull, D., 1965, Oxygen consumption and body temperature of newborn rabbits and kittens exposed to cold, J. Physiol. (London) 177:192–202.

    CAS  Google Scholar 

  119. Hull, D., 1966, The structure and function of brown adipose tissue, Br. Med. Bull. 22:92–96.

    PubMed  CAS  Google Scholar 

  120. Hull, D., and Hardman, M. J., 1970, Brown adipose tissue in newborn mammals, in: Brown Adipose Tissue (O. Lindberg, ed.), American Elsevier Publishing Co., New York.

    Google Scholar 

  121. Hull, D., and Segall, M. M., 1965, The contribution of brown adipose tissue to heat production in the newborn rabbit, J. Physiol. (London) 181:449–457.

    CAS  Google Scholar 

  122. Hull, D., and Segall, M. M., 1965, Sympathetic nervous control of brown adipose tissue and heat production in the newborn rabbit, J. Physiol. (London) 181:458–467.

    CAS  Google Scholar 

  123. Jansky, L., 1973, Non-shivering thermogenesis and its thermoregulatory significance, Biol. Rev. 48: 85–132.

    PubMed  CAS  Google Scholar 

  124. Jansky, L., and Hart, J. S., 1963, Participation of skeletal muscle and kidney during non-shivering thermogenesis in cold-acclimated rats, Can. J. Biochem. 41:953–964.

    Article  CAS  Google Scholar 

  125. Jenkinson, D. M., Noble, R. C., and Thompson, G. E., 1968, Adipose tissue and heat production in the newborn ox (Bos taurus), J. Physiol. (London) 195:639–646.

    CAS  Google Scholar 

  126. Joel, C. D., 1965, The physiological role of brown adipose tissue, in: Handbook of Physiology (A. E. Renold and G. F. Cahill, Jr., eds.), Sect. 5, pp. 59–85, American Physiological Society, Washington, D.C.

    Google Scholar 

  127. Joel, C. D., Treble, D. H., and Ball, E. G., 1964, On a major role for brown adipose tissue in heat production during arousal from hibernation, Fed. Proc. Fed. Amer. Soc. Exp. Biol. 23:271.

    Google Scholar 

  128. Johannson, B., 1959, Brown fat: A review, Metabolism 8:221–240.

    Google Scholar 

  129. Joppich, G., and Schäfer, H., 1955, Unterkühlung bei Frühgeborenen, Dtsch. Med. Wochenschr. 80: 73–75.

    Article  PubMed  CAS  Google Scholar 

  130. Karlberg, P., 1952, Determination of standard energy metabolism (basal metabolism) in normal infants, Acta Paediatr. (Uppsala) 41 (Suppl. 89):3–151.

    Google Scholar 

  131. Karlberg, P., Moore, R. E., and Oliver, T. K., 1962, The thermogenic response of the newborn infant to noradrenaline, Acta Paediatr. (Uppsala) 51:284–292.

    Article  CAS  Google Scholar 

  132. Karlberg, P., Moore, R. E., and Oliver, T. K., 1965, Thermogenic and cardiovascular response of the newborn baby to noradrenaline, Acta Paediatr. (Uppsala) 54:225–238.

    Article  CAS  Google Scholar 

  133. Kintzel, H. W., 1957, Zur Frage der Warm- oder Kalthaltung der Frühgeborenen, Arch. Kinderheilkd. 154:238–247.

    PubMed  CAS  Google Scholar 

  134. Kintzel, H. W., 1968, Untersuchungen über die Auswirkungen langanhaltender Hypothermie auf das Frühgeborene, Dtsche. Gesundheitswes. 15:710.

    Google Scholar 

  135. Kleiber, M., 1961, The Fire of Life: An Introduction to Animal Energetics, John Wiley & Sons, New York.

    Google Scholar 

  136. Kleiber, M., Cole, H. H., and Smith, A. H., 1943, Metabolic rate of rat foetuses in vitro, J. Cell. Comp. Physiol. 22:167–176.

    Article  Google Scholar 

  137. LeBlanc, J., and Mount, L. E., 1968, Effects of noradrenaline and adrenaline on oxygen rate and arterial blood pressure in the newborn pig, Nature (London) 217:77, 78.

    Google Scholar 

  138. Leduc, J., 1961, Catecholamine production and release in exposure and acclimation to cold, Acta Physiol. Scand. 53: (Suppl. 183):1–101.

    Google Scholar 

  139. Lee, V. A.,and Iliff, A., 1956, The energy metabolism of infants and young children during postprandial sleep, Pediatrics 18:739–749.

    PubMed  Google Scholar 

  140. Lehmann, G., 1956, Das Gesetz der Stoffwechsel-reduktion (Oberflächengesetz), in: Handbuch der Zoologie (J. G. Helmcke and H. von Lengerken, eds.), Vol. 8, Part 4, Chapt. 4, pp. 1–32, Walter de Gruyter & Co., Berlin.

    Google Scholar 

  141. Levison, H., and Swyer, P. R., 1964, Oxygen consumption and the thermal environment in newly born infants, Biol. Neonate New Ser. 7:305–312.

    Article  CAS  Google Scholar 

  142. Lewis, R. C., Duval, A. M., and Iliff, A., 1943, Standards for the basal metabolism of children from 2 to 15 years of age, inclusive, J. Pediatr. 23:1.

    Article  Google Scholar 

  143. Lindberg, O. (ed.), 1970, Brown Adipose Tissue, American Elsevier Publishing Co., New York.

    Google Scholar 

  144. Mann, T. P., and Elliot, R. J. K., 1957, Neonatal cold injury due to accidental exposure to cold, Lancet 1:229–234.

    Article  Google Scholar 

  145. McCance, R. A., and Strangeways, W. M. B., 1954, Protein catabolism and oxygen consumption during starvation in infants, young adults and old men, Br. J. Nutr. 8:21–31.

    Article  PubMed  CAS  Google Scholar 

  146. McCance, R. A., and Widdowson, E. M., 1959, The effect of lowering the ambient temperature on the metabolism of the newborn pig, J. Physiol. (London) 147:124–134.

    CAS  Google Scholar 

  147. Mendler, N., Reulen, H. J., and Brendel, W., 1972, Cold swelling and energy metabolism in the hypothermic brain of rats and dogs, in: Hibernation and Hypothermia, Perspectives and Challenges (F. E. South, J. P. Hannon, J. R. Willis, E. T. Pengelley, and N. R. Alpert, eds.), Elsevier Publishing Co., Amsterdam-London-New York.

    Google Scholar 

  148. Merklin, R. J., 1974, Growth and distribution of human fetal brown fat, Anat. Rec. 178:637–646.

    Article  PubMed  CAS  Google Scholar 

  149. Meschia, G., Cotter, J. R., Makowski, E. L., and Barron, D. H., 1967, Simultaneous measurement of uterine and umbilical blood flows and oxygen uptakes, Q.J. Exp. Physiol. 52:1–18.

    Google Scholar 

  150. Mestyán, J., Járai, I., Bata, G., and Fekete, M., 1964, The basal metabolic rate of premature infants, Biol. Neonate 7:11–25.

    Article  Google Scholar 

  151. Mestyán, J., Járai, I., Bata, G., and Fekete, M., 1964, The significance of facial skin temperature in the chemical heat regulation of premature infants, Biol. Neonate 7:243–254.

    Article  Google Scholar 

  152. Mestyán, J., Járai, I., Kekete, M., and Soltész, G., 1969, Specific dynamic action in premature infants kept at and below the neutral temperature, Pediatr. Res. 3:41–50.

    Article  PubMed  Google Scholar 

  153. Mestyán, J., Varga, F., Fohl, E., and Heim, T., 1962, Oxygen consumption of hyper- and hypothermic premature infants, Arch. Dis. Child. 37: 466–469.

    Article  PubMed  Google Scholar 

  154. Moll, W., and Bartels, H., 1960, Eine kritische Prüfung der offenen und der geschlossenen Methode zur Bestimmung des O2- Verbrauches nach Veränderung der inspiratorischen Sauerstoffkonzentration, Pflügers. Arch. ges. Physiol. 271:583–594.

    Article  CAS  Google Scholar 

  155. Montieth, J. L., and Mount, L. E. (eds.), 1974, Heat Loss front Animals and Man, Butterworths, London.

    Google Scholar 

  156. Moore, R. E., and Underwood, M. C., 1960, Possible role of noradrenaline in control of heat production in the newborn mammal, Lancet 1:1277, 1278.

    Google Scholar 

  157. Moore, R. E., and Underwood, M. C., 1962, Hexamethonium, hypoxia and heat production in newborn and infant kittens and puppies, J. Physiol. (London) 161:30–53.

    CAS  Google Scholar 

  158. Moore, R. E., and Underwood, M. C., 1963, The thermogenic effects of noradrenaline in newborn and infant kittens and other small mammals. A possible hormonal mechanism in the control of heat production, J. Physiol. (London) 168:290–317.

    CAS  Google Scholar 

  159. Mordhorst, H., 1933, Über die chemische Wärmeregulation frühgeborener Säuglinge, Monatsschr. Kinderheilkd. 55:174–191.

    CAS  Google Scholar 

  160. Mount, L. E., 1959, The metabolic rate of the newborn pig in relation to environmental temperature and to age, J. Physiol. (London) 147:333–345.

    CAS  Google Scholar 

  161. Mount, L. E., 1964, Radiant and convective heat loss from the newborn pig, J. Physiol. (London) 173:96–113.

    CAS  Google Scholar 

  162. Mount, L. E., 1966, Basis of heat regulation in homeotherms, Br. Med. Bull. 22:84–87.

    PubMed  CAS  Google Scholar 

  163. Mount, L. E., 1968, The Climatic Physiology of the Pig, Edward Arnold, London.

    Google Scholar 

  164. Mount, L. E., 1974, The concept of thermal neutrality, in: Heat Loss from Animals and Man (J. L. Monteith and L. E. Mount, eds.), pp. 425–439, Butterworths, London.

    Google Scholar 

  165. Nadel, E.R., Bullard, R.W., and Stolwijk, J.A.J., 1971, Importance of skin temperature in the regulation of sweating, J. Appl. Physiol. 31:80–87.

    PubMed  CAS  Google Scholar 

  166. Nakayama, T., Hammel, H. T., Hardy, J. D., and J. D.,and Eisenman,J. S., 1963, Thermal stimulation of electrical activity of single units of the preoptic region, Amer. J. Physiol. 204:1122–1126.

    Google Scholar 

  167. Napolitano, L., 1965, The fine structure of adipose tissues, in: Handbook of Physiology (A. E. Renold and G. F. Cahill, Jr., eds.), Sect. 5, pp. 109–123, American Physiological Society, Washington D.C.

    Google Scholar 

  168. Nishi, Y., and Gagge, A. P., 1971, Humid temperature. A biophysical index of thermal sensation and discomfort, J. Physiol. (Paris) 3:365–368.

    Google Scholar 

  169. Novak, M., and Hahn, P., 1975, Early development of fat metabolism, in: Childhood Obesity (P.J. Collipp, ed.), Publishing Sciences Group, Acton, Massachusetts.

    Google Scholar 

  170. Novak, M., Hahn, P., Pardo, V., Monkus, E., and Alzamora, D., 1975, The effect of carnitine on respiration of mitochondria obtained from newborn and adult human subcutaneous white adipose tissue, Int. J. Biochem. 5:223–234.

    Article  Google Scholar 

  171. Novak, M., Penn-Walker, D., and Monkus, E. F., 1975, Oxydation of fatty acids by mitochondria obtained from newborn subcutaneous (white) adipose tissue, Biol. Neonate 25:95–107.

    CAS  Google Scholar 

  172. Ogawa, T., 1970, Local effect of skin temperature on threshold concentration of sudorific agents, J. Appl. Physiol. 28:18–22.

    PubMed  CAS  Google Scholar 

  173. Oliver, T. K., 1965, Temperature regulation and heat production in the newborn, Pediatr. Clin. North Amer. 12:765–779.

    Google Scholar 

  174. Parmelee, A. H., Jr., Brück, K., and Brück, M., 1962, Activity and inactivity cycles during the sleep of premature infants exposed to neutral temperature, Biol. Neonate 4:317–339.

    Article  Google Scholar 

  175. Pichotka, J., 1958, Behaglichkeitstemperaturen und Minimalumsätze bei Meerschweinchen, Pflügers. Arch. ges. Physiol. 268:9, 10.

    Google Scholar 

  176. Popovic, V., 1960, Survival time of hypothermic white rats (15°C) and ground squirrels (10°C), Amer. J. Physiol. 199:463–466.

    PubMed  CAS  Google Scholar 

  177. Pouliot, M., 1966, Catecholamine excretion in adrenodemedullated rats exposed to cold after chronic guanethidine treatment, Acta Physiol. Scand. 68: 164–168.

    Article  CAS  Google Scholar 

  178. Precht, H., Laudien, H., and Havsteen, B., 1973, The normal temperature range, in: Temperature and Life (H. Precht, J. Christopherson, H. Hensel, and W. Larcher, eds.), Springer-Verlag, Berlin-Heidelberg-New York.

    Google Scholar 

  179. Pribilowá;, H., 1968, The importance of thermo-receptive regions for the chemical thermoregulation of the newborn, Biol. Neonate 12:13–22.

    Article  Google Scholar 

  180. Prokopeva, E. M., 1960, The limits of overcooling and survival in puppies, in: The Problem of Acute Hypothermia (P. M. Starkov, ed.), pp. 226–236, Pergamon Press, New York.

    Google Scholar 

  181. Prusiner, S., Cannon, B., and Lindberg, O., 1970, Mechanisms controlling oxydative metabolism in brown adipose tissue. in: Brown Adipose Tissue (O. Lindberg, ed.), American Elsevier Publishing Co., New York-London-Amsterdam.

    Google Scholar 

  182. Rafael, J., Klaas, D., and Hohorst, H. J., 1968, Mitochondrien aus braunem Fettgewebe: Enzyme und Atmungskettenphosphorylierung während der prä- und postnatalen Entwicklung des interscapularen Fettkörpers des Meerschweinchens, Hoppe-Seyler’s Z. Physiol. Chem. 349:1711–1724.

    Article  PubMed  CAS  Google Scholar 

  183. Rubecz, I., and Mestyan, J., 1975, The partition of maintenance energy expenditure and the pattern of substrate utilization in intrauterine malnourished newborn infants before and during recovery, 1975, Acta Paediatr. Acad. Sci. Hung. 16:335–350.

    PubMed  CAS  Google Scholar 

  184. Ryser, G., and Jéquier, E., 1972, Study by direct calorimetry of thermal balance on the first day of life, Eur. J. Clin. Invest. 2:176–187.

    Article  PubMed  CAS  Google Scholar 

  185. Schaefer, K. E., and Wünnenberg, W., 1976, Threshold temperatures for shivering in acute and chronic hypercapnia, J. Appl. Physiol. 41:67–70.

    PubMed  CAS  Google Scholar 

  186. Schiff, D., Stern, L., and Leduc, J., 1966, Chemical thermogenesis in newborn infants: Catecholamine excretion and the plasma non-esterified fatty acid response to cold exposure, Pediatrics 37:577–582.

    PubMed  CAS  Google Scholar 

  187. Scopes, J. W., and Ahmed, I., 1966, Minimal rates of oxygen consumption in sick and premature newborn infants, Arch. Dis. Child. 41:407–415.

    Article  PubMed  CAS  Google Scholar 

  188. Scopes, J. W., and Ahmed, I., 1966, Range of critical temperatures in sick and premature newborn babies, Arch. Dis. Child. 41:417–419.

    Article  PubMed  CAS  Google Scholar 

  189. Silverman, W. A., 1959, The physical environment and the premature infant, Pediatrics 23:166–171.

    PubMed  CAS  Google Scholar 

  190. Silverman, W. A., Zamelis, A., Sinclair, J. C., and Agate, F. J., Jr., 1964, Warm nape of the newborn, Pediatrics 33:984–986.

    PubMed  CAS  Google Scholar 

  191. Simon, E., 1974, Temperature regulation: The spinal cord as a site of extrahypothalamic thermoregulatory functions, Rev. Physiol. Biochem. Pharmacol. 71:1–76.

    Article  PubMed  Google Scholar 

  192. Sinclair, J. C., Scopes, J. W., and Silverman, W. A., 1967, Metabolic reference standards for the neonate, Pediatrics 39:724–732.

    PubMed  CAS  Google Scholar 

  193. Smalley, R. L., and Dryer, R. L., 1963, Brown fat: Thermogenic effect during arousal from hibernation in the bat, Science 140:1333, 1334.

    Article  Google Scholar 

  194. Smith, R. E., and Hock, R. J., 1962, Brown fat: Thermogenic effector of arousal in hibernators, Science 140:190, 200.

    Google Scholar 

  195. Smith, R. E., and Horwitz, B. A., 1969, Brown fat and thermogenesis, Physiol. Rev. 49:330–425.

    PubMed  CAS  Google Scholar 

  196. Smith, R. E., and Roberts, J. C., 1964, Thermogenesis of brown adipose tissue in cold-acclimated rats, Amer. J. Physiol. 206:143–148.

    PubMed  CAS  Google Scholar 

  197. Stern, L., Lees, M. H., and Leduc, J., 1965, Environmental temperature, oxygen consumption and catecholamine excretion in newborn infants, Pediatrics 36:367–373.

    PubMed  CAS  Google Scholar 

  198. Stolwijk, J. A. J., and Hardy, J. D., 1966, Temperature regulation in man—A theoretical study, Pflügers. Arch. ges. Physiol. 291:129–162.

    Article  CAS  Google Scholar 

  199. Sulyok, E., Jéquier, E., and Prod’hom, L. S., 1973, Respiratory contribution to the thermal balance of the newborn infant under various ambient conditions, Pediatrics 51:641–650.

    PubMed  CAS  Google Scholar 

  200. Sulyok, E., Jéquier, E., and Prod’hom, L. S., 1973, Thermal balance of the newborn infant in a heat-gaining environment, Pediatr. Res. 7:888–900.

    Article  PubMed  CAS  Google Scholar 

  201. Sulyok, E., Jéquier, E., and Ryser, G., 1972, Effect of relative humidity on thermal balance of the newborn infant, Biol. Neonate 21:210–218.

    Article  PubMed  CAS  Google Scholar 

  202. Szegvári, G., Várnai, J., and Donhoffer, S., 1963, The effect of environmental temperature, hypoxia and hypercapnia on total heat production and the electrical activity of muscle in the rat: Shivering and non-shivering thermogenesis and the site of non-shivering thermogenesis, Acta Physiol. Acad. Sci. Hung. 23:49–62.

    Google Scholar 

  203. Szélenyi, Z., Zeisberger, E., and Brück, K., 1976, Effects of electrical stimulation in the lower brainstem on temperature regulation in the unanesthetized guinea-pig, Pflügers. Arch. ges. Physiol. 364:123–127.

    Article  Google Scholar 

  204. Taylor, P. M., 1960, Oxygen consumption in newborn rats, J. Physiol. (London) 154:153–168.

    CAS  Google Scholar 

  205. Thauer, R., and Brendel, W., 1962, Hypothermie, Prog. Surg. 2:73–271.

    Google Scholar 

  206. Wenger, C. B., Roberts, M. F., Nadel, E. R., and Stolwijk, J. A. J., 1975, Thermoregulatory control of finger blood flow, J. Appl. Physiol. 38:1078–1082.

    PubMed  CAS  Google Scholar 

  207. Wolf, H., and Melichar, V., 1968, Determinations of turnover of triglycerides, FFA and free glycerol following triglyceride infusion in preterm and full-term newborns, Z. Klin. Chem. 7:205, 206.

    Google Scholar 

  208. Wolf, H., Stave, U., Novak, M., and Monkus, F., 1974, Recent investigations on neonatal fat metabolism, J. Perinat. Med. 2:75.

    Article  PubMed  CAS  Google Scholar 

  209. Wünnenberg, W., 1976, Thermointegrative activity of hypothalamic structures, Isr. J. Med. Sci. 12(9): 1050–1051.

    PubMed  Google Scholar 

  210. Wünnenberg, W., and Brück, K., 1968, Single unit activity evoked by thermal stimulation of the cervical spinal cord in the guinea pig, Nature (London) 218:1268–1269.

    Article  Google Scholar 

  211. Wünnenberg, W., and Hardy, J.D., 1972, Response of single units of the posterior hypothalamus to thermal stimulation, J. Appl. Physiol. 33(5):547–552.

    PubMed  Google Scholar 

  212. Young, I. M., 1962, Vasomotor tone in the skin blood vessels of the newborn infant, Clin. Sci. 22:325–332.

    PubMed  CAS  Google Scholar 

  213. Zeisberger, E., 1966, Liver oxygen consumption of cold- and warm-acclimated rats and factors regulating liver oxidative metabolism, Helgol. Wiss. Meeresunters. 14:528–540.

    Article  Google Scholar 

  214. Zeisberger, E., and Brück, K., 1972, Effects of intrahypothalamically injected noradrenergic and cholinergic agents on thermoregulatory responses, in: The Pharmacology of Thermoregulation (E. Schönbaum and P. Lomax, eds,), pp. 232–243, S. Karger, Basel.

    Google Scholar 

  215. Zeisberger, E., and Brück, K., 1976, Alteration of shivering threshold in cold- and warm-adapted guinea pigs following intrahypothalamic injections of noradrenaline and of an adrenergic alpha receptor blocking agent, Pflügers. Arch. ges. Physiol. 362: 113–119.

    Article  CAS  Google Scholar 

  216. Zeisberger, E., Brück, K., Wünnenberg, W., and Wietasch, C., 1967, Das Ausmass der zitterfreien Thermogenese des Meerschweinchens in Abhängigkeit vom Lebensalter, Pflügers. Arch. ges. Physiol. 296:276–288.

    Article  CAS  Google Scholar 

  217. Znamenáćek, K., and Přibylowá, H., 1964, Some parameters of respiratory metabolism in the first three days after birth, Acta Paediatr. Scand. 53: 241–246.

    Article  Google Scholar 

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  1. Institute of Physiology, Justus Liebig University, D63, Giessen, West Germany

    Kurt Brück

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  1. Mailman Center for Child Development, University of Miami Medical School, USA

    Uwe Stave

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Brück, K. (1978). Heat Production and Temperature Regulation. In: Stave, U. (eds) Perinatal Physiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2316-7_21

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