Skip to main content
SpringerLink
Log in

Cell Interactions in Neuroblastoma

  • Chapter
Intercellular Communication

Abstract

Orderly and specific patterns of interconnections among nerve cells appear to be of primary significance in determining nervous system function. Accordingly, the question of how such interconnections develop and become stabilized is prominent in much present-day neurobiological research. This question has many experimentally separable aspects: for example, a developing neuron must extend neurites which make contact with other cells; these contacts must mature functionally until they can communicate, chemically or electrically; the contacts must be validated as being appropriate to the developmental plan of the organism; appropriate contacts must be stabilized; the cells making them may be inhibited from forming further connections with other cells; and inappropriate contacts should be made nonfunctional by deletion, by pre- or postsynaptic cell death, or by losing their ability to transmit.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Akeson, K., and Herschman, H. R., 1974, Modulation of cell-surface antigens of a murine neuroblastoma, Proc. Nat. Acad. Sci. U.S.A. 71:187.

    Article  CAS  Google Scholar 

  • Altman, J., 1971, Coated vesicles and synaptogenesis. A developmental study in the cerebellar cortex of the rat, Brain Res. 30:311.

    Article  PubMed  CAS  Google Scholar 

  • Amano, T. Richelson, E., and Nirenberg, M., 1972, Neurotransmitter synthesis by neuroblastoma clones, Proc. Nat. Acad. Sci. U.S.A. 69:258.

    Article  CAS  Google Scholar 

  • Amano, T., Hamprecht, B., and Kemper, W., 1974, High activity of choline acetyltransferase inducted in neuroblastoma x glia hybrid cells, Expt. Cell Res. 85:399.

    Article  CAS  Google Scholar 

  • Augusti-Tocco, G., and Sato, G., 1969, Establishment of functional clonal lines of neurons from mouse neuroblastoma, Proc. Nat. Acad. Sci. U.S.A. 64:311.

    Article  CAS  Google Scholar 

  • Batkin, S., Piette, L. H., and Wildman, E., 1970, Effect of muscle denervation on growth of transplanted tumor in mice, Proc. Nat. Acad. Sci. U.S.A. 67:1521.

    Article  CAS  Google Scholar 

  • Beckwith, J. B., and Perrin, E. V., 1963, In situ neuroblastomas: A contribution to the natural history of the neural crest tumors, Am. J. Pathol. 43:1089.

    PubMed  CAS  Google Scholar 

  • Bennett, M. R., McLachlan, E. M., and Taylor, R. S., 1973, The formation of synapses in mammalian striated muscle reinnervated with autonomic preganglionic nerves, J. Physiol. (London) 233:501.

    CAS  Google Scholar 

  • Black, I. B., Hendry, I. A., and Iverson, L. L., 1972, The role of post-synaptic neurones in the biochemical maturation of presynaptic cholinergic nerve terminals in a mouse sympathetic ganglion, J. Physiol. (London) 221:149.

    CAS  Google Scholar 

  • Blume, A., Gilbert, F., Wilson, S., Färber, J., Rosenberg, R., and Nirenberg, M., 1970, Regulation of acetylcholinesterase in neuroblastoma cells, Proc. Nat. Acad. Sci. U.S.A. 67:786.

    Article  CAS  Google Scholar 

  • Bray, D., 1973, Branching patterns of individual sympathetic neurons in culture, J. Cell Biol. 56:702.

    Article  PubMed  CAS  Google Scholar 

  • Bray, J. J., and Harris, A. J., 1975, Dissociation between nerve-muscle transmission and nerve trophic effects on rat diaphragm using type D botulinum toxin, J. Physiol. (London) 253:53.

    CAS  Google Scholar 

  • Brown, J. C., 1971, Surface glycoprotein characteristic of the differentiated state of neuroolastoma C-1300 cells, Expt. Cell Res., 69:440.

    Article  CAS  Google Scholar 

  • Burgen, A. S. V., Dickens, J., and Zatman, L. J., 1949, The action of botulinum toxin on the neuro-muscular junction, J. Physiol. (London) 109:10.

    CAS  Google Scholar 

  • Chalazonitis, A., and Green, L. A., 1974, Enhancement in excitability properties of mouse neuroblastoma cells cultured in the presence of dibutyryl cyclic AMP, Brain Res. 72:340.

    Article  PubMed  CAS  Google Scholar 

  • Cicero, T. J., Cowan, W. M., Moore, B. W., and Suntzeff, V. 1970, Cellular localization of the two brain specific proteins, S-100 and 14–3–2, Brain Res. 18:25.

    Article  PubMed  CAS  Google Scholar 

  • Cushing, H., and Wolbach, S. B., 1927, The transformation of a malignant paravertebral sympathicoblastoma into a benign ganglioneuroma, Am. J. Pathol. 3:203.

    PubMed  CAS  Google Scholar 

  • Diamond, J., and Miledi, R., 1962, A study of foetal and new-born rat muscle fibres, J. Physiol. (London) 162:393.

    CAS  Google Scholar 

  • Donohue, J. P., Garrett, R. A., Baehner, R. L., and Thomas, M. H., 1974, The multiple manifestations of neuroblastoma, J. Urol. 111:260.

    PubMed  CAS  Google Scholar 

  • Everson, T. C., and Cole, W. H., 1966, Spontaneous Regression of Cancer, Saunders, Philadelphia, Pennsylvania.

    Google Scholar 

  • Fields, K. L., Gosling, C., Megson, M., and Stem, P. L., 1975, New cell surface antigens in rat defined by tumors of the nervous system, Proc. Nat. Acad. Sci. U.S.A. 72:1296.

    Article  CAS  Google Scholar 

  • Gilman, A. G., and Nirenberg, M., 1971, Regulation of adenosine 3′,5′-cyclic monophosphate metabolism in cultured neuroblastoma cells, Nature (London) 23:356.

    Article  Google Scholar 

  • Glick, M. C., Kimhi, Y., and Littauer, U. Z., 1973, Glycopeptides from surface membranes of neuroblastoma cells, Proc. Nat. Acad. Sci. U.S.A. 70:1682.

    Article  CAS  Google Scholar 

  • Goldstein, M. N., 1967, Incorporation and release of 3H-catecholamines by cultured fetal human sympathetic nerve cells and neuroblastoma cells, Proc. Soc. Exp. Biol. Med. 125:993.

    PubMed  CAS  Google Scholar 

  • Goldstein, M. N., Burdman, J. A., and Journey, L. H., 1964, Long-term tissue culture of neuroblastomas. II. Morphological evidence for differentiation and maturation, J. Nat. Cancer Inst. 32:165.

    PubMed  CAS  Google Scholar 

  • Goldstein, M. N., Brodeur, G. M., and Ross, D., 1973, The effect of nerve growth factor and dibutyryl cyclic AMP on acetylcholinesterase in human and mouse neuroblastomas, Anat. Rec. 175:330.

    Google Scholar 

  • Gonzalez-Angulo, A., Keyes, H. A., and Reyna, A. N., 1965, The ultrastructure of ganglioneuroblastoma; observations on neoplastic ganglion cells, Neurology 15:242.

    PubMed  CAS  Google Scholar 

  • Greenberg, R., Rosenthal, I., and Falk, G. S., 1969, Electron microscopy of human tumors secreting catecholamines: Correlation with biochemical data, J. Neuropathol. Exp. Neurol. 28:475.

    Article  PubMed  CAS  Google Scholar 

  • Hafke, S. G., and Seeds, N. W., 1975, Neuroblastoma: The E. coli of neurobiology? Life Sci. 16:1649.

    Article  Google Scholar 

  • Hamprecht, B., Jaffe, B. M., and Philpott, G. W., 1973, Prostaglandin production by neuroblastoma, glioma and fibroblast cell lines; stimulation by N°, O2′-dibutyryl adenosine 3′,5′-cyclic monophosphate, FEBS Lett. 36:193.

    Article  PubMed  CAS  Google Scholar 

  • Harkins, J., Arsenault, M., Schlesinger, K., and Kates, T., 1972, Induction of neuronal functions: Acetylcholine-induced acetylcholinesterase activity in mouse neuroblastoma cells, Proc. Nat. Acad. Sci. U.S.A. 69:3161.

    Article  CAS  Google Scholar 

  • Harris, A. J., 1974, Role of acetylcholine receptors in synapse formation, in: Synaptic Transmission and Neuronal Interaction (M. V. L. Bennet, ed.), pp. 315–337, Raven Press, New York.

    Google Scholar 

  • Harris, A. J., and Dennis, M. J., 1970, Acetylcholine sensitivity and its distribution on mouse neuroblastoma cells. Science 167:1253.

    Article  PubMed  CAS  Google Scholar 

  • Harris, A. J., and Hopkins, W. G., 1974, Interaction between neuroblastoma and skeletal muscle cell lines in tissue culture, Eighth International Congress on Electron Microscopy, Canberra, Vol. 2, pp. 290–291.

    Google Scholar 

  • Harris, A. J., and Miledi, R., 1971, The effect of type D botulinum toxin on frog neuromuscular junctions, J. Physiol. (London) 217:497.

    CAS  Google Scholar 

  • Harris, A. J., Heinemann, S., Schubert, D., and Tarakis, H., 1971, Trophic interaction between cloned tissue culture lines of nerve and muscle, Nature (London) 231:296.

    Article  CAS  Google Scholar 

  • James, D. W., and Tresman, R. L., 1969, An electron-microscopic study of the de novo formation of neuromuscular junctions in tissue culture, Z. Zeilforsch. 100:126.

    Article  CAS  Google Scholar 

  • Kelly, A. M., and Zacks, S. I., 1969, The fine structure of motor endplate morphogenesis, J. Cell Biol. 42:154.

    Article  PubMed  CAS  Google Scholar 

  • Kidokoro, Y., and Heinemann, S., 1974, Synapse formation between clonal muscle cells and rat spinal cord expiants, Nature (London) 252:593.

    Article  CAS  Google Scholar 

  • Kidokoro, Y., Heinemann, S., Schubert, D., Brandt, B. L., and Klier, F. G., 1975, Synapse formation and neurotrophic effects on muscle cell lines, Cold Spring Harbor Symp. Quant. Biol. 40:373.

    Article  Google Scholar 

  • Klebe, R. J., and Ruddle, F. H., 1969, Neuroblastoma: Cell culture analysis of a differentiating stem cell system, J. Cell Biol. 43:69a.

    Google Scholar 

  • Kolber, A. R., Goldstein, M. H., and Moore, B. W., 1974, Effect of nerve growth factor on the expression of colchicine-binding activity and 14–3–2 protein in an established line of human neuroblastoma, Proc. Nat. Acad. Sci. U.S.A. 71:4203.

    Article  CAS  Google Scholar 

  • Littlefield, J. W., 1964, Selection of hybrids from mating of fibrolasts in vitro and their presumed recombinants, Science 145:709.

    Article  PubMed  CAS  Google Scholar 

  • Lopresti, V., Macagno, E. R., and Levinthal, C., 1974, Structure and development of neuronal connections in isogenic organisms: Transient gap junctions between growing optic axons and lamina neuroblasts, Proc. Nat. Acad. Sci. U.S.A. 71:1098.

    Article  CAS  Google Scholar 

  • Luse, S. A., 1964, Synaptic structures occurring in a neuroblastoma, Arch. Neurol. 11:185.

    Article  PubMed  CAS  Google Scholar 

  • McMorris, F. A., and Ruddle, F. H., 1974, Expression of neuronal phenotypes in neuroblastoma cell hybrids, Dev. Biol. 39:226.

    PubMed  CAS  Google Scholar 

  • Minna, J., Nelson, P., Peacock, J., Glazer, D., and Nirenberg, M., 1971, Genes for neuronal properties expressed in neuroblastoma x L cell hybrids, Proc. Nat. Acad. Sci. U.S.A. 68:234.

    Article  CAS  Google Scholar 

  • Misugi, K., Misubi, N., and Newton, W. A., 1968, Fine structural study of neuroblastoma, ganglioneuroblastoma and pheochromocytoma, Arch. Pathol. 86:160.

    PubMed  CAS  Google Scholar 

  • Monard, D., Solomon, F., Rentsh, M., and Gysin, R., 1973, Glia-induced morphological differentiation in neuroblastoma cells, Proc. Nat. Acad. Sci. U.S.A. 70:1894.

    Article  CAS  Google Scholar 

  • Murphy, R. A. Pantazis, N. J., Arnason, B. G. W., and Young, M., 1975, Secretion of a nerve growth factor by mouse neuroblastoma cells in culture, Proc. Nat. Acad. Sci. U.S.A. 72:1895.

    Article  CAS  Google Scholar 

  • Murray, M. R., and Stout, A. P., 1947, Distinctive characteristics of the sympathicoblastoma cultivated in vitro, Am. J. Pathol. 23:429.

    PubMed  CAS  Google Scholar 

  • Nelson, B., Ruffner, W., and Nirenberg, M., 1969, Neuronal tumor cells with excitable membranes grown in vitro, Proc. Nat. Acad. Sci. U.S.A. 64:1004.

    Article  CAS  Google Scholar 

  • Nelson, P., Christian, C., and Nirenberg, M., 1976, Synapse formation between clonal neuroblastoma × glioma hybrid cells and striated muscle cells, Proc. Nat. Acad. Sci. U.S.A. 73:123.

    Article  CAS  Google Scholar 

  • Nelson, P. G., 1973, Electrophysiological studies of normal and neoplastic cells in tissue culture, in: Tissue Culture of the Nervous System (G. Sato, ed.), pp. 135–160, Plenum Press, New York.

    Google Scholar 

  • Nelson, P. G., 1975, Nerve and muscle cells in culture, Physiol. Rev. 55:1.

    Article  PubMed  CAS  Google Scholar 

  • Nelson, P. G., Peacock, J. H., and Amano, T., 1971a, Responses of neuroblastoma cells to iontophoretically applied acetylcholine, J. Cell. Physiol. 77:353.

    Article  CAS  Google Scholar 

  • Nelson, P. G., Peacock, J. H., Amano, T., and Minna, J., 1971b, Electrogenesis in mouse neuroblastoma cells in vitro, J. Cell. Physiol. 77:337.

    Article  CAS  Google Scholar 

  • Nurse, C. A., and O’Lague, P. H., 1975, Formation of cholinergic synapses between dissociated sympathetic neurons and skeletal myotubes of the rat in cell culture, Proc. Nat. Acad. Sci. U.S.A. 72:1955.

    Article  CAS  Google Scholar 

  • O’Lague, P. H., Obata, K., Claude, P., Furshpan, E. J., and Potter, D. D., 1974, Evidence for cholinergic synapses between dissociated rat sympathetic neurones in cell culture, Proc. Nat. Acad. Sci. U.S.A. 71:3602.

    Article  Google Scholar 

  • Olmstead, J., Carlson, K., Klebe, R., Ruddle, F., and Rosenbaum, J., 1970, Isolation of microtubule protein from cultured mouse neuroblastoma cells, Proc. Nat. Acad. Sci. U.S.A. 65:129.

    Article  Google Scholar 

  • Papaioannou, V. E., McBurney, M. W., Gardner, R. L., and Evans, M. L., 1975, Fate of teratocarcinoma cells injected into early mouse embryos, Nature (London) 258:70.

    Article  CAS  Google Scholar 

  • Patterson, P. H., and Chun, L. L. Y., 1974, The influence of non-neuronal cells on catecholamine and acetylcholine synthesis and accumulation in cultures of dissociated sympathetic neurons, Proc. Nat. Acad. Sci. U.S.A. 71:3607.

    Article  CAS  Google Scholar 

  • Peacock, J. H., and Nelson, P. G., 1973, Chemosensitivity of mouse neuroblastoma cells invitro, J. Neurobiol. 4:363.

    Article  PubMed  CAS  Google Scholar 

  • Peacock, J. H., Minna, J., Nelson, P. G., and Nirenberg, M., 1972, Use of aminopterin in selecting electrically active neuroblastoma cells, Expt. Cell Res. 73:367.

    Article  CAS  Google Scholar 

  • Peacock, J. H., McMorris, F. A., and Nelson, P. G., 1973, Electrical excitability and chemosensitivity of mouse neuroblastoma x mouse or human fibrolast hybrids, Expt. Cell Res. 79:199.

    Article  Google Scholar 

  • Perez, V. J., Olney, J. W., Cicero, T. J., Moore, B. W., and Bahn, B. A., 1970, Wallerian degeneration in rabbit optic nerve: Cellular localization in the central nervous system of the S-100 and 14–3–2 proteins, J. Neurochem. 17:511.

    Article  PubMed  CAS  Google Scholar 

  • Peterson, E. R., and Crain, S. M., 1970, Innervation in cultures of fetal rodent skeletal muscle by organotypic expiants of spinal cord from different animals, Z. Zellforsch. Mikrosk. Anat. 106:1.

    Article  PubMed  CAS  Google Scholar 

  • Prasad, K. N., and Gilmer, K. N., 1974, Demonstration of dopamine-sensitive adenylate cyclase in malignant neuroblastoma cells and change in sensitivity of adenylate cyclase to catecholamines in “differentiated” cells, Proc. Nat. Acad. Sci. U.S.A. 71:2525.

    Article  CAS  Google Scholar 

  • Prasad, K, N., and Hsie, A. W., 1971, Morphologic differentiation of mouse neuroblastoma cells induced in vitro by dibutryl adenosine 3′,5′-cyclic monophosphate, Nature NewBiol 233:141.

    CAS  Google Scholar 

  • Prasad, K. N., Gilmer, K. N., and Sahu, S. K., 1974, Demonstration of acetylcholine sensitive adenyl cyclase in malignant neuroblastoma cells in culture, Nature (London) 249:765.

    Article  CAS  Google Scholar 

  • Rees, R. P., Bunge, M. B., and Bunge, R. P., 1976, Morphological changes in the neuritic growth cone and target neuron during synaptic junction development in culture, J. CellBiol 68:240.

    Article  CAS  Google Scholar 

  • Revoltella, R., Bertolini, L., Pediconi, M., and Vigneti, E., 1974, Specific binding of nerve growth factor (NGF) by murine CI300 neuroblastoma cells, J. Expt. Med. 140:437.

    Article  CAS  Google Scholar 

  • Rosenbaum, L., 1973, Differentiation of neuroblastoma cells in hypertonic medium: Formation of cell junctions and synaptic vesicles, Neurosa. Res. Prog. Bull. 11:448.

    Google Scholar 

  • Rosenberg, R. N., Vandeventer, L., deFrancesco, L., and Friedkin, M. E., 1971, Regulation of the synthesis of choline-o-acetyltransferase and thymidylate synthetase in mouse neuroblastoma in cell culture, Proc. Nat. Acad. Sci. U.S.A. 68:1436.

    Article  CAS  Google Scholar 

  • Ruffner, B. W., and Smith, M., 1974, Biochemical differentiation of a murine ganglioneuroblastoma in tissue culture, Expt. Cell Res. 89:442.

    Article  CAS  Google Scholar 

  • Sahu, S. K., and Prasad, K. N., 1975, Effect of neurotransmitters and prostaglandin E1 on cyclic AMP levels in various clones of neuroblastoma cells in culture, J. Neurochem. 24:1267.

    Article  PubMed  CAS  Google Scholar 

  • Sato, G., 1973, Tissue Culture of the Nervous System, Plenum Press, New York.

    Google Scholar 

  • Schubert, D. Humphreys, S., Baroni, C., and Cohn, M., 1969, In vitro differentiation of a mouse neuroblastoma, Proc. Nat. Acad. Sci. U.S.A. 64:316.

    Article  CAS  Google Scholar 

  • Schubert, D., Humphreys, S., de Vitry, F., and Jacob, F., 1971, Induced differentiation of a neuroblastoma, Dev. Biol. 25:514.

    Article  PubMed  CAS  Google Scholar 

  • Shubert, D., Harris, A. J., Heinemann, S., Kidokoro, Y., Patrick, J., and Steinbach, H. J., 1973, Differentiation and interaction of clonal cell lines of nerve and muscle, in: Tissue Cultureof the Nervous System (G. Sato, ed.), pp. 55–86, Plenum Press, New York.

    Google Scholar 

  • Schubert, D., Heinemann, S., Carlisle, W., Tarikas, H., Kimes, B., Patrick, J., Steinbach, J. H., Culp, W., and Brandt, B. L., 1974, Clonal cell lines from the rat central nervous system,Nature (London) 249:224.

    Article  CAS  Google Scholar 

  • Seeds, N. W., Gilman, A. G., Amano, T., and Nirenberg, M. W., 1970, Regulation of axon formation by clonal lines of a neural tumor, Proc. Nat. Acad. Sci. U.S.A. 66:160.

    Article  CAS  Google Scholar 

  • Simantov, R., and Sachs, L., 1973, Regulation of acetylcholine receptors in relation to acetylcholinesterase in neuroblastoma cells, Proc. Nat. Acad. Sci. U.S.A. 70:2902.

    Article  CAS  Google Scholar 

  • Steinbach, J. H., 1975, Acetylcholine responses on clonal myogenic cells in vitro, J. Physiol. (London) 247:393.

    CAS  Google Scholar 

  • Steinbach, J. H., Harris, A. J., Patrick, J., Schubert, D., and Heinemann, S., 1973, Nerve-muscle interaction in vitro. Role of acetylcholine, J. Gen. Physiol. 62:255.

    Article  PubMed  CAS  Google Scholar 

  • Stelzner, D. J., Martin, A. H., and Scott, G. L., 1973, Early stages of synaptogenesis in the cervical spinal cord of the chick embryo, Z. Zellforsch. 138:475.

    Article  PubMed  CAS  Google Scholar 

  • Thesleff, S., 1960, Supersensitivity of skeletal muscle produced by botulinum toxin, J. Physiol. (London) 151:598.

    CAS  Google Scholar 

  • Tresman, R. L., and Evans, M. J., 1975, A light and electron microscopical study of the nervous tissue of mouse teratomas, J. Neurocytol 4:301.

    Article  Google Scholar 

  • Truding, R., Shelanski, M. L., Daniels, M. P., and Morell, P., 1974, Comparison of surface membranes isolated from cultured murine neuroblastoma cells in the differentiated or undifferentiated state, J. Biol. Chem. 249:3973.

    PubMed  CAS  Google Scholar 

  • Ts’o, M. O. M., Fine, B. S., and Zimmerman, L. E., 1970a, The nature of retinoblastoma. II. Photoreceptor differentiation: An electron microscopic study, Am. J. Ophthalmol. 69:350.

    Google Scholar 

  • Ts’o, M. O. M., Zimmerman, L. E., and Fine, B. S., 1970b, The nature of retinoblastoma. I. Photoreceptor differentiation: A clinical and histopathological study, Am. J. Ophthalmol. 69:339.

    Google Scholar 

  • Voorhess, M. L., 1974, Neuroblastoma-pheochromocytoma: Products and pathogenesis, Ann. N.Y. Acad. Sci. 230:187.

    Article  PubMed  CAS  Google Scholar 

  • Wilkerson, J. A., Van de Water, J. M., and Goepfert, H., 1967, Role of embryonic induction in benign transformation of neuroblastomas, Cancer 20:1335.

    Article  PubMed  CAS  Google Scholar 

  • Yaffe, D., 1968, Retention of differentiation potentialities during prolonged cultivation of myogenic cells, Proc. Nat. Acad. Sci. U.S.A. 61:477.

    Article  CAS  Google Scholar 

  • Yokoyama, M., Okada, K., Tokue, A., and Takayasu, H., 1973, Ultrastructural and biochemical study of benign ganglioneuroma, Virchows Arch. Pathol. Anat. 361:195.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology, University of Otago Medical School, P.O. Box 913, Dunedin, New Zealand

    A. J. Harris & W. G. Hopkins

Authors
  1. A. J. Harris
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. W. G. Hopkins
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Puerto Rico, San Juan, Puerto Rico

    Walmor C. De Mello

Rights and permissions

Reprints and permissions

Copyright information

© 1977 Plenum Press, New York

About this chapter

Cite this chapter

Harris, A.J., Hopkins, W.G. (1977). Cell Interactions in Neuroblastoma. In: De Mello, W.C. (eds) Intercellular Communication. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2283-2_7

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-2283-2_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2285-6

  • Online ISBN: 978-1-4684-2283-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation