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Intercellular Communication and Cancer

  • Chapter
Intercellular Communication

Abstract

Among the several different forms of cell interactions known to exist in multicellular organisms intercellular communication provides the most direct form of communication by allowing free exchange of ions and small molecules between neighboring cells via permeable membrane junctions. This type of communication has been implicated in various biological functions such as cell differentiation, embryonic development, and tissue growth regulation. In this chapter we will review highlights of functional and structural evidence of junctional communication in normal and cancerous tissues and discuss the existing hypotheses concerning the possible significance of cell junctions in cancer.

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Authors and Affiliations

  1. Department of Physiology and Biophysics, University of Miami, School of Medicine, Miami, Florida, 33152, USA

    Roobik Azarnia

  2. Department of Anatomy, The University of Iowa, College of Medicine, Iowa City, Iowa, 52242, USA

    William J. Larsen

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  1. Roobik Azarnia
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  2. William J. Larsen
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  1. University of Puerto Rico, San Juan, Puerto Rico

    Walmor C. De Mello

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© 1977 Plenum Press, New York

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Azarnia, R., Larsen, W.J. (1977). Intercellular Communication and Cancer. In: De Mello, W.C. (eds) Intercellular Communication. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2283-2_6

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  • DOI: https://doi.org/10.1007/978-1-4684-2283-2_6

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