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Type III Hyperlipoproteinemia

  • Chapter
Low Density Lipoproteins

Abstract

Several synonyms for familial type III hyperlipoproteinemia are often used. These include familial “broad-β” disease, “floating-β” disorder, dysbetalipoproteinemia, xanthoma tuberosum, and idiopathic hypercholesterolemic xanthomatosis with hyperlipemia. Type III hyperlipoproteinemia is a genetically determined lipoprotein disorder manifested by an increased concentration of both cholesterol and triglyceride in the plasma. It is characterized by the presence of a lipoprotein that floats between density 1.006–1.019 in the postabsorptive state. Moreover, the concentration of VLDL (d < 1.006) is increased, and, frequently, chylomicrons are present in the fasting plasma. Often, the plasma lipoprotein electrophoresis pattern is characterized by a “broad-β” band.

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  1. Josef R. Patsch

    Present address: Division of Atherosclerosis and Lipoprotein Research, Baylor College of Medicine—The Methodist Hospital, Houston, Texas, 77030, USA

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  1. Medical Department, University of Innsbruck, A-6020, Innsbruck, Austria

    Josef R. Patsch

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  1. Josef R. Patsch
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  1. The Upjohn Company, Kalamazoo, Michigan, USA

    Charles E. Day

  2. Department of Biochemistry, University of Louisville School of Medicine, Louisville, Kentucky, USA

    Robert S. Levy

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© 1976 Plenum Press, New York

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Patsch, J.R. (1976). Type III Hyperlipoproteinemia. In: Day, C.E., Levy, R.S. (eds) Low Density Lipoproteins. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2250-4_8

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  • DOI: https://doi.org/10.1007/978-1-4684-2250-4_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2252-8

  • Online ISBN: 978-1-4684-2250-4

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