Abstract
The sialic acids are widely distributed in nature, either free or as components of homo- and heterosaccharides, glycoproteins, and glycolipids (Tuppy and Gottschalk, 1972). Although a considerable literature has accumulated on sialic acids and the sialo compounds, a unified concept about the biological roles of sialic acids has not yet developed due to both their heterogeneous occurrence and their possible involvement in diverse cellular functions (Faillard and Schauer, 1972; Gottschalk, 1972; Marshall, 1972; Mehrishi, 1972; Curtis, 1973; Hughes, 1973; Schauer, 1973; Weiss, 1973). This chapter will approach a better understanding of the biological roles of sialic acids by examining their occurrence in nature. A possible correlation between the evolution and biological roles of sialic acids is considered.
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Ng, SS., Dain, J.A. (1976). The Natural Occurrence of Sialic Acids. In: Rosenberg, A., Schengrund, CL. (eds) Biological Roles of Sialic Acid. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2226-9_2
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