Abstract
Wilms’ tumor was virtually incurable before pediatric surgeons, notably Ladd1, perfected their surgical techniques. Steady improvements thereafter added radiation therapy2 and chemotherapy. The routine postoperative use of actinomycin-D, as reported by Farber3, produced a two-year survival rate of 81% in patients managed from the outset by an experienced team using combination therapy. Wolff and his colleagues4 demonstrated the value of cyclic actinomycin-D given over a prolonged period after operation, and otherss 5,6 showed that vincristine sulfate was effective in the management of these children.
Supported in part by U.S.P.H.S. Grant No. R1O CA 11722.
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References
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D’ANGIO, G. J., BECKWITH, J. B., BISHOP, H. C., BRESLOW, N., EVANS, A. E., GOODWIN, W., KING, L. R., PICKETT, L. K., SINKS, L., SUTOW, W. W. and WOLFF, J. A.: The National Wilms’ Tumor Study: A Progress Report. Cancer. (In press)
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© 1973 Ontario Cancer Treatment and Research Foundation
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D’angio, G.J. et al. (1973). The National Wilms’ Tumor Study: A Progress Report. In: Godden, J.O. (eds) Cancer in Childhood. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2070-8_7
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DOI: https://doi.org/10.1007/978-1-4684-2070-8_7
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