Burkitt’s Lymphoma

Abstract

Before the indentification of the tumor syndrome which subsequently became known as Burkitt’s lymphoma, workers in different parts of tropical Africa had recognized an undue prevalence of a number of apparently unconnected tumors in children. These included retinoblastoma, neuroblastoma, sarcomas of the upper and lower jaws and granulosa-cell tumors of the ovary, all of which were composed of small round cells with similar histological appearances. A flaccid paraplegia of rapid onset without evidence of vertebral collapse and tumors of the long bones of the limbs were seen more frequently than might be expected.