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The Electromechanochemical Model of Mitochondrial Structure and Function

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Book cover Membrane Structure and Mechanisms of Biological Energy Transduction

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Abstract

The gross configurational changes which mitochondria undergo during energization and deenergization were the experimental foundation stones for the conformational model which we first proposed in 1967.1–3 Out of these studies emerged the notion of the energized state of the transducing unit and the notion of coupling the relaxation of the energized unit either to the synthesis of ATP or to active transport.4 Implicit in the conformational model is the conservation of energy in a metastable state4,5 of the transducing unit rather than in a high-energy covalent intermediate.

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Authors and Affiliations

  1. Institute for Enzyme Research, University of Wisconsin, Madison, Wisconsin, 53706, USA

    David E. Green & Sungchul Ji

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  1. David E. Green
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  2. Sungchul Ji
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  1. Department of Chemistry, Imperial College of Science and Technology, London S.W.7, England

    J. Avery

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Green, D.E., Ji, S. (1972). The Electromechanochemical Model of Mitochondrial Structure and Function. In: Avery, J. (eds) Membrane Structure and Mechanisms of Biological Energy Transduction. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2016-6_15

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  • DOI: https://doi.org/10.1007/978-1-4684-2016-6_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2018-0

  • Online ISBN: 978-1-4684-2016-6

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