Abstract
An approach to the problem of mitochondrial energy transduction is outlined. The approach is based on the fundamental assumption that there is an intimate relation between the mechanisms of enzyme catalysis and energy transduction. The implications of this assumption for the coupling of two chemical reactions and the coupling of a chemical reaction to an ion flux are discussed.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
D. E. Green, Proc. Nat. Acad. Sci. U.S., 67 (1970) 544.
D. E. Green and J. H. Young, Amer. Sci., 59 (1971) 92.
R. Lumry, in: A Treatise on Electron and Coupled Energy Transfer in Biological Systems, T. King and M. Klingenberg (eds.), Dekker, New York, 1969.
P. D. Boyer, in: Biological Oxidations, T. P. Singer (ed.), Interscience, New York, 1968, p. 193.
R. Lumry and R. Biltonen, in: Structure and Stability of Biological Macromolecules, S. N. Timasheff, G. D. Fasman, (eds.), Dekker, New York, 1969, p. 65.
W. Jencks, in: Current Aspects of Biochemical Energetics: Fritz Lipman Dedicatory Volume, N. Kaplan and E. Kennedy (eds.), Academic Press, New York, 1966, p. 272.
D. Koshland, Jr., Proc. Nat. Acad. Sci. U.S., 44 (1958) 98;
D. Koshland, Jr., Cold Spring Harbor Symp. Quat. Biol. 28 (1963) 473.
I. Prigogine, Introduction to Thermodynamics of Irreversible Processes, 3rd Ed., Interscience, New York, 1967, p. 25.
H. Rottenberg, S. R. Caplan and A. Essig, in: Membranes and Ion Transport, Vol, 1, E. Bittar (ed.), Interscience, New York, 1970, p. 165.
M. Klingenberg and P. Schollmeyer, Proc, 5th Intern. Congr. Biochem., Moscow 1961, Vol. 5, Pergamon, London, 1963, p. 46.
S. Muraoka and E. C. Slater, Biochim. Biophys. Acta, 180 (1969) 221.
G. F. Azzone and S. Massari, Eur. J. Biochem., 19 (1971) 97.
E. Rossi and G. F. Azzone, Eur. J. Biochem., 12 (1970) 319.
R. S. Cockrell, E. J. Harris and R. Pressman, Nature, 215 (1967) 1487.
R. A. Reid, J. Moyle and P. Mitchell, Nature, 212 (1966) 257.
L. Danielson and L. Ernster, in: Energy-Linked Functions of Mitochondria, B. Chance (ed.), Academic Press, New York, 1963, p. 157.
R. J. van de Stadt, F. J. R. M. Nienwenhuis and K. van Dam, Biochim. Biophys. Acta, 234 (1971) 173.
L. L. Grinius, A. A. Jasaitis, Y. P. Kadziauskas, E. A. Liberman, V. P. Skulachev, V.P. Topali, L. M. Tsofina and M. A. Vladimirova, Biochim. Biophys. Acta, 216 (1970) 1.
L. Ernster and C. P. Lee, Ann. Rev. Biochem., 33 (1964) 729.
M. Klingenberg, Essays Biochem., 6 (1970) 119.
J. H. Young (manuscript in preparation).
P. D. Boyer, in: Current Topics in Bioenergetics, Vol. II, D. R. Sanadi (ed.), Academic Press, New York, 1967, p. 99.
P. Mitchell, Biol. Rev. Cambridge Phil. Soc., 41 (1966) 445.
J. H. Young, G. A. Blondin and D. E. Green, in: Physical Principles of Neuronal and Organismic Behavior, Gordon and Breach, New York, in press.
J. H. Young, G. A. Blondin and D. E. Green, Proc. Nat. Acad. Sci. USA, 68 (1971) 1364.
E. A. Liberman and V. P. Skulachev, Biochim. Biophys. Acta, 216 (1970) 30.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1972 Plenum Publishing Company Limited
About this chapter
Cite this chapter
Young, J.H. (1972). An Enzymological Approach to Mitochondrial Energy Transduction. In: Avery, J. (eds) Membrane Structure and Mechanisms of Biological Energy Transduction. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2016-6_13
Download citation
DOI: https://doi.org/10.1007/978-1-4684-2016-6_13
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-2018-0
Online ISBN: 978-1-4684-2016-6
eBook Packages: Springer Book Archive