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Thyroxine Binding to Anterior Pituitary Proteins in Vitro: Correlation with Anterior Pituitary Growth

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Hormones and Brain Function

Abstract

The main role in the regulation of anterior pituitary function is played by the hypothalamic hypophysiotrophic factors or hormones (Guillemin 1964, 1967, Schally et al. 1968, McCann et al. 1968, McCann and Porter 1969, Harris and George 1969, Schreiber 1969, Campbell 1970, Meites 1970). Most of the available evidence shows that the primary effect of these factors is the release of anterior pituitary hormones into the blood, i.e., their secretion, and not their increased synthesis. The whole question is still awaiting a final answer and it will probably not be long before it is demonstrated that the hypothalamic hypophysiotrophic hormones directly influence biosynthesis of the anterior pituitary hormones, as preliminary evidence already exists (Geschwind 1970).

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Authors and Affiliations

  1. Laboratory for Endocrinology and Metabolism IIIrd Medical Clinic Faculty of General Medicine, Charles University, Prague, Czechoslovakia

    V. Schreiber

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  1. V. Schreiber
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  1. University Medical School, Pécs, Hungary

    K. Lissák (Member of the Hungarian Academy of Sciences, Professor of Physiology) (Member of the Hungarian Academy of Sciences, Professor of Physiology)

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© 1973 Akadémiai Kiadó, Budapest, Hungary

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Schreiber, V. (1973). Thyroxine Binding to Anterior Pituitary Proteins in Vitro: Correlation with Anterior Pituitary Growth. In: Lissák, K. (eds) Hormones and Brain Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2007-4_14

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  • DOI: https://doi.org/10.1007/978-1-4684-2007-4_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2009-8

  • Online ISBN: 978-1-4684-2007-4

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