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Biochemical Responses to Environmental Stress pp 119–131Cite as

The Effects of Chlorinated Hydrocarbons on the Hepatic Monooxygenase System

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Abstract

Monooxygenases, also referred to as mixed function oxidases, are enzymes which in the presence of an electron donor and molecular oxygen catalyze the incorporation of oxygen into aliphatic and aromatic substrates. The stoichiometry of this reaction can be described as follows:

$$AH + {O_2} + BH + {H^ + } \to AOH + B + {H_2}O$$

where AH is the substrate and BH is the electron donor.

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Authors and Affiliations

  1. Lederle Laboratories, Division of American Cyanamid Company, Pearl River, New York, 10965, USA

    David Kupfer

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  1. David Kupfer
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Editors and Affiliations

  1. Departments of Environmental and Industrial Health and Biological Chemistry, The University of Michigan Medical Center, 48104, Ann Arbor, Michigan, USA

    I. A. Bernstein (Professor of Environmental and Industrial Health and of Biological Chemistry) (Professor of Environmental and Industrial Health and of Biological Chemistry)

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© 1971 Plenum Press, New York

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Kupfer, D. (1971). The Effects of Chlorinated Hydrocarbons on the Hepatic Monooxygenase System. In: Bernstein, I.A. (eds) Biochemical Responses to Environmental Stress. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1917-7_8

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  • DOI: https://doi.org/10.1007/978-1-4684-1917-7_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1919-1

  • Online ISBN: 978-1-4684-1917-7

  • eBook Packages: Springer Book Archive

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