Abstract
In contrast to heteroploid cell lines, human diploid cell lines have a finite lifetime in vitro; the ultimate fate of human diploid cells growing in vitro has been studied by Hay flick and Moorhead [1] and by Hayflick [2]. However, biochemical and cytophysiological characterization of young and old diploid cells, as compared to cells that can be cultivated indefinitely, has been limited to only a few studies.
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References
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© 1970 Plenum Press, New York
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Michl, J., Svobodová, J. (1970). RNA and DNA Metabolism in Aging Cultured Cells. In: Holečková, E., Cristofalo, V.J. (eds) Aging in Cell and Tissue Culture. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1821-7_8
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DOI: https://doi.org/10.1007/978-1-4684-1821-7_8
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