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Isolation of Pure Antibodies

  • Chapter
Biochemistry of Antibodies

Abstract

The possibility of isolating pure antibodies is of interest in several respects. Pure preparations are, first of all, necessary for a detailed study of the properties and structure of these highly specific serum proteins. The availability of pure antibodies considerably facilitates immunological investigations, for example, the study of antibody—antigen interaction. Finally, it should be recalled that antibodies are widely used as highly specific reagents, for example, to detect antigen in tissues, and also as effective therapeutic agents against many infectious diseases. In any case, pure antibody preparations are obviously more convenient to use than the presently employed immune serums or their fractions, which contain considerable quantities of nonspecific proteins in addition to antibody.

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  1. Institute of Molecular Biology, Academy of Sciences of the USSR, Moscow, Russia

    Roal’d S. Nezlin

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© 1970 Plenum Press, New York

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Nezlin, R.S. (1970). Isolation of Pure Antibodies. In: Biochemistry of Antibodies. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1791-3_2

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