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Estrogen Effects on the Skeleton

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Metabolic Effects of Gonadal Hormones and Contraceptive Steroids

Abstract

Although estrogens have been widely used in the treatment of postmenopausal osteoporosis for the last quarter century, surprisingly little is known of the effects of these hormones on adult skeletal metabolism. Furthermore, as has been usual in endocrine research, more is known of lower animals than of man. I will review the better known (and probably less relevant) skeletal effects of estrogens In birds, mice, and rats, will summarize what is known of estrogen effects in higher mammals and in menopausal women, will review with you our own results using calcium balance and calcium kinetic studies in women, and will conclude with a tentative effort at an explanation of estrogen effects on the adult skeleton.

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Author information

Authors and Affiliations

  1. Creighton University School of Medicine, Omaha, Nebraska, USA

    Robert P. Heaney M.D

Authors
  1. Robert P. Heaney M.D
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Editor information

Editors and Affiliations

  1. Harvard Medical School, USA

    Hilton A. Salhanick (Professor of Obstetrics and Gynecology, Member) (Professor of Obstetrics and Gynecology, Member)

  2. Center for Population Studies, Harvard School of Public Health, USA

    Hilton A. Salhanick (Professor of Obstetrics and Gynecology, Member) (Professor of Obstetrics and Gynecology, Member)

  3. Washington University School of Medicine, USA

    David M. Kipnis (Professor of Medicine) (Professor of Medicine)

  4. College of Physicians and Surgeons, Columbia University, USA

    Raymond L. Vande Wiele (Professor of Obstetrics and Gynecology) (Professor of Obstetrics and Gynecology)

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© 1969 Plenum Press, New York

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Heaney, R.P. (1969). Estrogen Effects on the Skeleton. In: Salhanick, H.A., Kipnis, D.M., Wiele, R.L.V. (eds) Metabolic Effects of Gonadal Hormones and Contraceptive Steroids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1782-1_37

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  • DOI: https://doi.org/10.1007/978-1-4684-1782-1_37

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1784-5

  • Online ISBN: 978-1-4684-1782-1

  • eBook Packages: Springer Book Archive

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