Abstract
The medical aspects of the science of photobiology are among the most important parts of this discipline, since they are concerned primarily with direct effects of nonionizing radiation on humans. Two organ systems are directly affected by sunlight: the eye and the skin. The eye is discussed in Chapter 10; this chapter will examine primarily cutaneous reactions to the sun.(1–4)
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
B. E. Johnson, F. Daniels, Jr., and I. A. Magnus, Response of human skin to ultraviolet light, Photophysiology 4, 139–202 (1968).
M. A. Pathak and J. H. Epstein, Normal and abnormal reactions of man to light, in: Dermatology in General Medicine (T. B. Fitzpatrick, K. A. Arndt, W. H. Clark, A. Z. Eisen, E. J. Van Scott, and J. H. Vaughan, eds.) pp. 977–1036, McGraw-Hill, New York (1971).
F. Urbach (ed.), The Biologic Effects of Ultraviolet Radiation ,Pergamon, New York (1969).
T. B. Fitzpatrick, M. A. Pathak, L. C. Harber, M. Seiji, and A. Kukita (eds.), Sunlight and Man ,University of Tokyo Press, Tokyo (1974).
I. Willis, A. Kligman, and J. H. Epstein, Effects of long ultraviolet rays on human skin: Photoprotective or photoaugmentative?, J. Invest. Dermatol. 59, 416–420 (1972).
J. H. Epstein, K. Fukuyama, and K. Fye, Effects of ultraviolet radiation on the mitotic cycle and 1. DNA, RNA and protein synthesis in mammalian epidermis in vivo, Photochem. Photobiol. 12, 57–65(1970).
J. H. Epstein, Adverse cutaneous reactions to the sun, in: Yearbook of Dermatology (F. D. Malkinson and R. W. Pearson, eds.), pp. 5–43, Yearbook Medical Publ., Chicago, III. (1971).
D. S. Snyder and W. H. Eaglstein, Intradermal antiprostaglandin agents and sunburn, J. Invest. Dermatol. 62,47–50(1974).
G. F. Wilgram, R. L. Kidd, W. S. Krawczyk, and P. L. Cole, Sunburn effect on keratinosomes, Arch. Dermatol. 101, 505–519(1970).
K. Wier, K. Fukuyama, and W. L. Epstein, Nuclear changes during light-induced depression of ribonucleic acid and protein synthesis in human epidermis, Lab. Invest. 25, 451–456 (1971).
K. Fukuyama, W. L. Epstein, and J. H. Epstein, The effect of ultraviolet light on RNA and protein synthesis in differentiated epidermal cells, Nature 216, 1031–1032 (1967).
G. A. Soffen and H. F. Blum, Quantitative measurements in changes in mouse skin following a single dose of ultraviolet light, J. Cell Comp. Physiol. 58, 81–96 (1961).
W. S. Bullough and E. B. Laurence, Tissue homeostasis in adult mammals, in: Advances in Biology of Skin ,Vol. 7, Carcinogenesis (W. Montagna and R. L. Dobson, eds.), pp. 1–36, Pergamon, Oxford (1966).
J. J. Voorhees, E. A. Duell, and W. H. Kelsey, Dibutyryl cyclic AMP inhibition of epidermal cell division, Arch. Dermatol. 105, 384–386(1972).
J. E. Cleaver, Repair of damaged DNA in human and other eukaryotic cells, in: Nucleic Acid-Protein Interactions-Nucleic Acid Synthesis in Viral Infection (D. W. Ribbons, J. F. Woessner, and J. Schultz, eds.), pp. 87–112, North-Holland, Amsterdam (1971).
J. E. Cleaver, Repair processes for photochemical damage in mammalian cells, Adv. Radiat. Biol. 4, 1–75(1974).
J. E. Cleaver and D. Bootsma, Xeroderma pigmentosum: Biochemical and genetic characteristics, Annu. Rev. Genet. 9, 19–38 (1975).
A. R. Lehman, S. Kirk-Bell, C. F. Arlett, M. C. Paterson, P. H. M. Lohman, E. A. de Weerd-Kastelein, and D. Bootsma, Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation, Proc. Natl. Acad. Sci. USA 72, 219–223 (1975).
R. L. Olson, J. Nordquist, and M. A. Everett, The role of epidermal lysosomes in melanin pigmentation, Br. J. Dermatol. 83, 189–199(1970).
J. H. Epstein, K. Fukuyama, and R. L. Dobson, Ultraviolet light carcinogenesis, in: The Biologic Effects of Ultraviolet Radiation (F. Urbach, ed.), pp. 551–568, Pergamon, New York (1969).
W. L. Epstein, K. Fukuyama, and J. H. Epstein, Early effects of ultraviolet light on DNA synthesis in human skin in vivo, Arch. Dermatol. 100, 84–89 (1969).
H. F. Blum, Carcinogenesis By Ultraviolet Light ,Princeton University Press, Princeton, N.J. (1959).
J. H. Epstein, Ultraviolet carcinogenesis, Photophysiology 5, 235–273 (1970).
V. M. Maher, L. M. Oullette, R. D. Curren, and J. J. McCormick, Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cells, Nature 261, 593–595 (1976).
J. H. Epstein, Photoallergy: A review, Arch. Dermatol. 106, 741–748 (1972).
H. F. DeLuca, Vitamin D: The vitamin and the hormone, Fed. Proc. 33, 2211–2219 (1974).
W. F. Loomis, Skin-pigmentation regulation of vitamin D biosynthesis in man, Science 157, 501–506(1967).
K. H. Kaidbey and A. M. Kligman, Photopigmentation with trioxsalan, Arch. Dermatol. 109, 674–677(1974).
J. A. Parrish, T. B. Fitzpatrick, L. Tanenbaum, and M. A. Pathak, Photochemotherapy of psoriasis with oral methoxsalen and long-wave ultraviolet light, N. Engl. J. Med. 291, 1207–1211 (1974).
L. E. Bockstahler, C. D. Lytle, and K. B. Hellman, A Review of Photodynamic Therapy for Herpes Simplex: Benefits and Potential Risks ,DHEW Publication No. (FDA) 75–8013. (Available from the Bureau of Radiological Health, Rockville, MD 20852.) (1974).
Phototherapy in the Newborn ,Final report of the Committee, Division of Medical Sciences, National Research Council (2101 Constitution Ave.) Washington D.C., 20418 (1974).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1977 Plenum Press, New York
About this chapter
Cite this chapter
Epstein, J.H. (1977). Photomedicine. In: Smith, K.C. (eds) The Science of Photobiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1713-5_7
Download citation
DOI: https://doi.org/10.1007/978-1-4684-1713-5_7
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-1715-9
Online ISBN: 978-1-4684-1713-5
eBook Packages: Springer Book Archive