Abstract
The toxic action of an insecticide is dependent on its reactivity to the biochemical target (e.g., reactivity of paraoxon toward acetylcholinesterase). Toxicity in vivo, however, is considerably modulated by rates of absorption, metabolism, and elimination of the insecticide; thus, metabolic fate plays a pivotal role in the toxicity and persistence of insecticides. Species variance in toxicity is often due to differential rates or routes of biotransformation of the parent compound or one of the metabolites.
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© 1989 Plenum Press, New York
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Levi, P.E., Hodgson, E. (1989). Monooxygenations: Interactions and Expression of Toxicity. In: Narahashi, T., Chambers, J.E. (eds) Insecticide Action. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1324-3_13
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DOI: https://doi.org/10.1007/978-1-4684-1324-3_13
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