Abstract
Nearly half a century after his first publications on the anatomy of the eighth nerve, Lorente de No (1981) portrayed “the primary acoustic nuclei” as “a miniature brain that has a cerebellum of its own, the tuberculum acousticum”. Here, selected aspects of this “brain” are discussed on the basis of recent literature. Included are also some preliminary immunocytochemical data from our institute (Osen et al., 1987), obtained by postembedding staining of 0.5 Aim resin sections of glutaraldehydefixed tissue, using locally produced antisera against conjugated glycine and GABA (Storm-Mathisen et al., 1983; Somogyi et al., 1984; Ottersen and Storm-Mathisen, 1984; Ottersen et al., 1987). As specificity tests are used preabsorption with amino acid glutaraldehyde complexes and coincubation with test sections containing six spatially separate amino acid conjugates (Ottersen, 1987).
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References
Adams, J. C., 1979, Ascending projections to the inferior colliculus, J. Comp. Neurol., 183: 519–538.
Adams, J. C., 1983, Multipolar cells in the ventral cochlear nucleus project to the dorsal cochlear nucleus and the inferior colliculus, Neurosci. Lett., 37:205–208.
Arnesen, A. R. and Osen, K. K., 1978, The cochlear nerve in the cat: topography, cochleotopy, and fiber spectrum, J. Comp. Neurol., 178: 661–678.
Blackstad, T. W., Osen, K. K. and Mugnaini, E., 1984, Pyramidal neurones of the dorsal cochlear nucleus: a Golgi and computer reconstruction study in cat, Neuroscience, 13:827–854.
Bourk, T. R., Mielcarz, J. P. and Norris, B. E., 1981, Tonotopic organization of the anteroventral cochlear nucleus of the cat, Hearing Res., 4:215–241.
Brawer, J. R., Morest, D. K. and Kane, E. C., 1974, The neuronal architecture of the cochlear nucleus of the cat, J. Comp. Neurol., 155: 251–300.
Brown, M. C., 1987, Morphology of labeled afferent fibers in the guinea pig cochlea, J. Comp. Neurol., 260:591–604.
Cant, N. B. and Casseday, J. H., 1986, Projections from the anteroventral cochlear nucleus to the lateral and medial superior olivary nuclei, J. Comp. Neuro1., 247:457–476.
Cant, N. B. and Gaston, K. C., 1982, Pathways connecting the right and left cochlear nuclei, J. Comp. Neurol., 212:313–326.
Cant, N. B. and Morest, D. K., 1978, Axons from non-cochlear sources in the anteroventral cochlear nucleus of the cat. A study with the rapid Golgi method, Neuroscience, 3:1003–1029.
Cant, N. B. and Morest, D. K., 1979, Organization of the neurons in the anterior division of the anteroventral cochlear nucleus of the cat. Light-microscopic observations, Neuroscience, 4:1909–1923.
Caspary, D. M., Rybak, L. P. and Faingold, C. L., 1985, The effects of inhibitory and excitatory amino-acid neurotransmitters on the response properties of brainstem auditory neurons, in: “Auditory biochemistry”, D. G. Drescher, ed., Charles C. Thomas Publ., Springfield Ill.
Faye-Lund, H. and Osen, K. K., 1985, Anatomy of the inferior colliculus in rat, Anat. Embryo1., 171:1–20.
Hackney, C. M. and Pick, G. F., 1986, The distribution of spherical cells in the anteroventral cochlear nucleus of the guinea pig. Brit. J. Audiol., 20:215–220.
Harrison, J. M. and Feldman, M. L., 1970, Anatomical aspects of the cochlear nucleus and superior olivary complex, in: “Contributions to sensory physiology”, W. D. Neff, ed., Academic Press, New York and London.
Harrison, J. M. and Irving, R., 1964, Nucleus of the trapezoid body: dual afferent innervation, Science, 143:473–474.
Harrison, J. M. and Irving, R., 1965, The anterior ventral cochlear nucleus, J. Comp. Neurol., 124:15–21.
Harrison, J. M. and Irving, R., 1966, The organization of the posterior ventral cochlear nucleus in the rat, J. Comp. Neurol., 126:391–402.
Itoh, K., Nomura, S., Konishi, A., Yasui, Y., Sugimoto, T. and Muzino, N., 1986, A morphological evidence of direct connections from the cochlear nuclei to tensor tympani motoneurons in the cat: a possible afferent limb of the acoustic middle ear reflex pathways, Brain. Res., 375:214–219.
Itoh, K., Kamiya, H., Mitani, A., Yasui, Y., Takada, M. and Mizuno, N., 1987, Direct projections from the dorsal column nuclei and the spinal trigeminal nuclei to the cochlear nuclei in the cat, Brain Res., 400:145–150.
Liberman, M. C. and Simmons, D. D., 1985, Applications of neuronal labeling techniques to the study of the peripheral auditory system, J. Acoust. Soc. Am., 78:312–319.
Lorente de Nó, R., 1933, Anatomy of the eighth nerve. III. General plan of structure of the primary cochlear nuclei, Laryngoscope, 43:327–350.
Lorente de Nó, R., 1981, “The primary acoustic nuclei”, Raven Press, New York.
Moore, J. K., 1980, The primate cochlear nuclei: loss of lamination as a phylogenetic process, J. Comp. Neurol., 193:609–629.
Mugnaini, E., 1985, GABA neurons in the superficial layers of the rat dorsal cochlear nucleus: light and electron microscopic immunocy- tochemistry, J. Comp. Neurol., 235:61–81.
Mugnaini, E., Osen, K. K., Dahl, A.-L., Friedrich, V. L., jr., and Korte, G., 1980, Fine structure of granule cells and related interneurons (termed Golgi cells) in the cochlear nuclear complex of cat, rat and mouse, J. Neurocytol., 9:537–570.
Osen, K. K., 1969a, Cytoarchitecture of the cochlear nuclei in the cat, J. Comp. Neurol., 136:453–484.
Osen, K. K., 1969b, The intrinsic organization of the cochlear nuclei in the cat, Acta Otolaryngol., 67:352–359.
Osen, K. K., 1970, Course and termination of the primary afferents in the cochlear nuclei of the cat. An experimental anatomical study, Arch. Ital. Biol., 108:21–51.
Osen, K. K., 1983, Orientation of dendritic arbors studied in Golgi sections of the cat dorsal cochlear nucleus, in: “Mechanisms of hearing”, W. R. Webster and L. M. Aitkin, eds., Monash University Press, Clayton.
Osen, K. K., Ottersen, O. P. and Storm-Mathisen, J., 1987, Glycine-like immunoreactivity in the rat dorsal cochlear nucleus (DCN), Neuroscience, Suppl. 22:S788.
Ottersen, O. P., 1987, Postembedding light- and electron microscopic immunocytochemistry of amino acids: description of a new model system allowing identical conditions for specificity testing and tissue processing, Exp. Brain Res., (in press).
Ottersen, O. P., Davanger, S. and Storm-Mathisen, J., 1987, Glycine-like immunoreactivity in the cerebellum of rat and Senegalese baboon, Papio papio: a compari3son with the distribution of GABA-like immunoreactivity and with H glycine and H GABA uptake, Exp. Brain Res., 66:211–221.
Ottersen, O. P. and Storm-Mathisen, J., 1984, Glutamate- and GABA- containing neurons in the mouse and rat brain, as demonstrated with a new immunocytochemical technique, J. Comp. Neurol., 229:374–392.
Rouiller, E. M., Cronin-Schreiber, R., Fekete, D. M. and Ryugo, D. K., 1986, The central projections of intracellularly labeled auditory nerve fibers in cats: an analysis of terminal morphology. J. Comp. Neurol., 249:261–278.
Smith, P. H. and Rhode, W. S., 1985, Electron microscopic features of physiologically characterized, HRP-labeled fusiform cells in the cat dorsal cochlear nucleus, J. Comp. Neurol., 237:127–143.
Somogyi, P., Hodgson, A. J., Smith, A. D., Nunzi, M. G., Gorio, A. and Wu, J.-Y., 1984, Different populations of GABA ergic neurons in the visual cortex and hippocampus of cat contains somatostatin- or cholecystokinin-immunoreactive material, J. Neurosci., 4:2590–2603.
Storm-Mathisen, J., Leknes, A. K., Bore, A. T., Vaaland, J. L., Edminson, P., Haug, F.-M. S. and Ottersen, O. P., 1983, First visualization of glutamate and GABA in neurones by immunocytoche- mistry, Nature, London, 301:517–520.
Wenthold, R. J., 1987, Evidence for a glycinergic pathway connecting the two cochlear nuclei; an immunocytochemical and retrograde transport study, Brain Res., 415:183–187.
Wouterlood, F. G., and Mugnaini, E., 1984, Cartwheel neurons of the dorsal cochlear nucleus: A Golgi-electron microscopic study in rat, J. Comp. Neurol., 227:136–157.
Wouterlood, F. G., Mugnaini, E., Osen, K. K. and Dahl, A.-L., 1984, Stellate neurons in rat dorsal cochlear nucleus studied with combined Golgi impregnation and electron microscopy: synaptic connections and mutual coupling by gap junctions, J. Neurocytol., 13: 639–664.
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© 1988 Plenum Press, New York
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Osen, K.K. (1988). Anatomy of the Mammalian Cochlear Nuclei; a Review. In: Syka, J., Masterton, R.B. (eds) Auditory Pathway. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1300-7_11
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DOI: https://doi.org/10.1007/978-1-4684-1300-7_11
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