Skip to main content

Studies on the Correlation Between the Quantity of LDL-Binding Sites of Platelets and the Serum Cholesterol Levels

  • Chapter
Lipoproteins and Atherosclerosis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 210))

  • 135 Accesses

Abstract

It was demonstrated by several authors that LDL in vitro and in vivo increase the in vitro platelet aggregation1,2 and other platelet functions.3,4 This hypersensitivity of platelets may contribute in vivo to an accerelated atherogenesis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. R. Farbiszewski, A. Skryzydlewski, and K. Worowski, The effect of lipoprotein fractions on adhesiveness and aggregation of blood platelets, Thromb. Diath. Haemorrh. 21: 89 /1969/

    PubMed  CAS  Google Scholar 

  2. D. G. Hassal, L.A. Forrest, K.R. Bruckdorfer, C. B. Marenah, P. Turner, C. Cortese, N. E. Miller, and B. Lewis, Influence of plasma lipoproteins on platelet aggregation in a normal male population, Arteriosclerosis 3: 332 /1983/

    Article  Google Scholar 

  3. P. Gautheron and J. Renaud, Hyperlipemia induced hypercoagulable state in rat. Role of an increased activity of platelet phosphatidyl serine in response to certain dietary fatty acids, Thromb. Res. 1: 353 /1972/

    Article  CAS  Google Scholar 

  4. R. Abbate, P. A., Modesti, A. Fortini, A. Lombardi, M. Matucci, G. F. Gensini, G. G. Neri Serneri, R. Fellin, G. Yalero, and G. Crepaldi, Decreased number of PGD2 binding sites on platelets from patients with type II/a hyperlipoproteinemia, Atherosclerosis 54: 167 /1985/

    Article  PubMed  CAS  Google Scholar 

  5. J. Siedel, H. Schlumberger, S. Klose, J. Ziegen-horn, and A. W. Wahlefeld, Improved reagent for the enzymatic determination of serum cholesterol, J. Clin. Chem. Clin. Biochem. 19: 838 /1981/

    Google Scholar 

  6. J. R. Baumgartner, and C., Haudenschild, Adhesion of platelets to subendothelium, Ann. NY. Acad. Sci, 201: 22 /1972/

    Article  PubMed  CAS  Google Scholar 

  7. R. L. Czervionke, C. J. Hoak, and G. L. Fry, Effect of aspirin on thrombin induced adherence of platelets to cultured cells from the blood vessel wall, J. Glin. Invest. 62: 847 /1978/

    Article  CAS  Google Scholar 

  8. C. A. Carvalho, R. W. Colman, and R. S. Lees, Platelet function in hyperlipoproteinemia, If. Engl. J. Med. 290: 434 /1974/

    Article  CAS  Google Scholar 

  9. M. Aviram, and J. G. Brook, Platelet interaction with high and low density lipoproteins, Atherosclerosis 46: 259 /1983/

    Article  PubMed  CAS  Google Scholar 

  10. E. Koller, P. Koller, and W. Dolesehel, Specific binding sites on human platelets for plasma lipoproteins, Hoppe-Seyler’g Physiol. Ghem. 363: 395 /1982/

    Article  CAS  Google Scholar 

  11. M. Aviram, and J. G. Brook, Lipid metabolism and cell function, Israel J. Med. Sci. 17: 482 /1981/

    Google Scholar 

  12. A. V. Mazurov, S.N. Preobrazhensky, V. L. Leytin, V. S. Repin, and V. N. Sinirnov, Study of low density lipoprotein interaction with platelets by flow cytofluorimetry, EBBS Letters 137: 319 /1982/

    CAS  Google Scholar 

  13. S. J. Shattil, R. Anaya-Galindo, and J. Bennett, Platelet hypersensitivity induced by cholesterol incorporation, J. Clin. Invest. 55 636 /1975/

    Article  PubMed  CAS  Google Scholar 

  14. B. P. Schick, and P. K. Schick, Cholesterol exchange in platelets, erythrocytes, and megakaryocytes, Biochem. Biophys. Acta 833: 281 /1985/

    PubMed  CAS  Google Scholar 

  15. R. M. Kramer, J. A. Jakubowski, R. Vaillancourt, and D. Deykin, Effect of membrane cholesterol on phospholipid metabolism in thrombin-stimulated platelets, J. Biol. Chem. 257: 6844 /1982/

    PubMed  CAS  Google Scholar 

  16. J. Beitz, M. Panse, and W. Förster, Low density lipoprotein from male volunteers stimulated the thromboxane formation by human platelets, Prostagland, Leukotr. Med. 10: 443 /1983/

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Plenum Press, New York

About this chapter

Cite this chapter

Geró, S., Szody, É., Lengyel, É., Simon, G. (1987). Studies on the Correlation Between the Quantity of LDL-Binding Sites of Platelets and the Serum Cholesterol Levels. In: Malmendier, C.L., Alaupovic, P. (eds) Lipoproteins and Atherosclerosis. Advances in Experimental Medicine and Biology, vol 210. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1268-0_35

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-1268-0_35

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1270-3

  • Online ISBN: 978-1-4684-1268-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics