Clinical Syndrome and Lipid Metabolism in Hereditary Deficiency of Apolipoproteins A-I and C-III, Variant 1
The DNA alteration in hereditary deficiency of apoA-I and C-III, variant 1, is one of the best characterized of all the dyslipoproteinemias. Since that discovery lipid metabolism has been examined in some detail in the two patients with this disorder. This report will review the clinical findings in the two patients and present results of studies on the physico-chemical properties and metabolism of their lipoproteins.
KeywordsExtensive Atherosclerosis Fractional Catabolic Rate Tangier Disease Corneal Clouding VLDL Triglyceride
Unable to display preview. Download preview PDF.