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Clinical Syndrome and Lipid Metabolism in Hereditary Deficiency of Apolipoproteins A-I and C-III, Variant 1

  • Robert A. Norum
  • Trudy M. Forte
  • Petar Alaupovic
  • Henry N. Ginsberg
Part of the Advances in Experimetal Medicine and Biology book series (AEMB, volume 201)

Abstract

The DNA alteration in hereditary deficiency of apoA-I and C-III, variant 1, is one of the best characterized of all the dyslipoproteinemias. Since that discovery lipid metabolism has been examined in some detail in the two patients with this disorder. This report will review the clinical findings in the two patients and present results of studies on the physico-chemical properties and metabolism of their lipoproteins.

Keywords

Extensive Atherosclerosis Fractional Catabolic Rate Tangier Disease Corneal Clouding VLDL Triglyceride 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Robert A. Norum
    • 1
  • Trudy M. Forte
    • 2
  • Petar Alaupovic
    • 3
  • Henry N. Ginsberg
    • 4
  1. 1.Department of Internal MedicineHenry Ford HospitalDetroitUSA
  2. 2.Donner LaboratoryUniversity of CaliforniaBerkeley, BerkeleyUSA
  3. 3.Laboratory of Lipid and Lipoprotein StudiesOklahoma Medical Research FoundationOklahoma CityUSA
  4. 4.Department of MedicineMt. Sinai School of MedicineNew YorkUSA

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