Abstract
The discovery of a causal association between a deficiency of one of the enzymes of the purine degradative pathway and a selective cellular immunodeficiency has initiated studies on the relation of the purine/pyrimidine metabolism and lymphocyte function.
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Scharenberg, J.G.M., Spaapen, L.J.M., Rijkers, G.T., Wadman, S.K., Staal, G.E.J., Zegers, B.J.M. (1986). Mechanisms of Deoxyguanosine Toxicity for Human T and B Lymphocytes. In: Nyhan, W.L., Thompson, L.F., Watts, R.W.E. (eds) Purine and Pyrimidine Metabolism in Man V. Advances in Experimental Medicine and Biology, vol 195B. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-1248-2_29
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DOI: https://doi.org/10.1007/978-1-4684-1248-2_29
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