Skip to main content

Trematode Infections of Man

  • Chapter
Chemotherapy of Parasitic Diseases

Abstract

A consideration of the chemotherapy of trematode infections of man will invariably be unevenly distributed with respect to the parasites involved. The great preponderance of attention must be devoted to the blood flukes or schistosomes, because of their great medical importance and because so much is known about their treatment. The remaining flukes, having various degrees of medical importance and having a lesser body of therapeutic lore, can be covered more briefly.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ambroise-Thomas P. Goullier A. and Peyron F. 1984 Therapeutic results in opisthorchiasis with praziquantel in a reinfection-free environment in France Arzneimittelforsch. 34 II): 1177–117

    PubMed  CAS  Google Scholar 

  • Abaza, H. H., Hammouda, N., Abd Rabbo, H., and Shafei, A. Z., 1978, Chemotherapy of schistosomal colonic polyposis with oxamniquine, Trans. R. Soc. Trop. Med. Hyg. 72:602–604.

    Article  PubMed  CAS  Google Scholar 

  • Bennett, J. K., and Depenbusch, J. W., 1984, The chemotherapy of schistosomiasis, in: Parasitic Diseases, Vol. 2: The Chemotherapy (J. M. Mansfield, ed.), pp. 73–131, Dekker, New York.

    Google Scholar 

  • Bunnag, D., Pungpark, S., Harinasuta, T., Viravan, C., Vanijanonta, S., Suntharasamai, P., Migasena, S., Charoenlarp, P., Riganti, M., and LooAreesuwan, S., 1984, Opisthorchis viverrini: Clinical experience with praziquantel in hospital for tropical diseases, Arzneimittelforsch. 34(11): 1173–1174.

    PubMed  CAS  Google Scholar 

  • Campbell, W. C., and Cuckler, A. C., 1961, The prophylactic effect of topically applied cedarwood oil on infection with Schistosoma mansoni in mice, Am. J. Trop. Med. Hyg. 10:712–715.

    PubMed  CAS  Google Scholar 

  • Campbell, W. C., and Cuckler, A. C., 1967, Inhibition of egg production of Schistosoma mansoni in mice treated with nicarbazin, J. Parasitol. 53:977–980.

    Article  PubMed  CAS  Google Scholar 

  • Campbell, W. C., and Rogers, E. F., 1971, Effect of nitrocarbanilides on Schistosoma mansoni, J. Parasitol. 57:1372–1373.

    Article  PubMed  CAS  Google Scholar 

  • Campbell, W. C, Bartels, E., and Cuckler, A. C, 1978, A method for detecting chemotherapeutic activity against Schistosoma mansoni in mice, J. Parasitol. 64:69–77.

    Article  PubMed  CAS  Google Scholar 

  • Cao, W. J., He, L. Y., Zhong, H. L. Chung, H. L., Xu, Z. S., Bi, Y. C., Yu, G. T., Zhang, Q. C., Li, K. C., Yang, E. V., She, G., and Li, H. J., 1984, Paragonimiasis: Treatment with praziquantel in 40 human cases and in 1 cat, Arzneimittelforsch. 34(II): 1203–1204.

    PubMed  CAS  Google Scholar 

  • Chen, C. Y., and Hsieh, W. C., 1984, Clonorchis sinensis: Epidemiology in Taiwan and clinical experience with praziquantel, Arzneimittelforsch. 34(II): 1160–1162.

    PubMed  CAS  Google Scholar 

  • Chen, M. G., Hua, X. J., Wan, Z. R., Weng, Y. Q., Wang, M. J., Zhu, P. J., He, B. Z., and Xu, M. Y., 1983, Praziquantel in 237 cases of clonorchiasis sinensis, Chin. Med. J. 96:935–940 (English transi.).

    PubMed  CAS  Google Scholar 

  • Cho, S. Y., Kang, S. Y., and Lee, J. B., 1984, Metagonimiasis in Korea, Arzneimittelforsch. 34(II): 1211–1213.

    PubMed  CAS  Google Scholar 

  • Davis, A., 1982, Manage of the patient in schistosomiasis, in: Schistosomiasis (P. Jordan and G. Webbe, eds.), pp. 184–226, Heineman Medical Books, London.

    Google Scholar 

  • Davis, A., and Bailey, D. R., 1969, Metrifonate in urinary schistosomiasis, Bull. WHO 41:209–224.

    PubMed  CAS  Google Scholar 

  • Davis, A., and Wegner, D. H. G., 1979, Multicenter trials of praziquantel in the treatment of human schistosomiasis: Designs and techniques, Bull. WHO 51:767–772.

    Google Scholar 

  • Davis, A., Biles, J. E., and Wrich, A. M., 1979, Initial experience with praziquantel in the treatment of human infection due to Schistosoma haematobium, Bull. WHO 57:773–780.

    PubMed  CAS  Google Scholar 

  • Delolme, H., Cot, M., Cavallo, A., Kouka-Bemba, D., and Sentilhes, L., 1983, Réflexions sur le traitement de masse des bilharzioses à Schistosoma haematobium dans les états membres de l’Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC), Bull. Soc. Pathol. Exot Fil. 76:534–541.

    CAS  Google Scholar 

  • de Souza Dias, L. C. S., Pedro, R. V., and Deberaldini, E. R., 1982, Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/or hycanthone: Resistance of Schistosoma mansoni to schistosomicidal agents, Trans. R. Soc. Trop. Med. Hyg. 76:652–659.

    Article  PubMed  Google Scholar 

  • Dhiensiri, T., Eua-Ananta, Y., Bunnag, D., Harinasuta, T., and Schelp, P. F., 1984, Roentgenographically controlled healing of gallbladder lesions in opisthorchiasis after praziquantel treatment, Arzneimittelforsch. 34(II):1175–1177.

    PubMed  CAS  Google Scholar 

  • Doehring, E., Feldmeier, H., Dafalla, A. A., Ehrich, J. H., Vester, U., and Poggensee, U., 1984, Intermittent chemotherapy with trichlorfon (metrifonate) reverses proteinuria, hematuria, and leukocyturia in urinary schistosomiasis: Results of a three–year field study, J. Infect. Dis. 149:615–620.

    Article  PubMed  CAS  Google Scholar 

  • Feldmeier, H., Doehring, E., Daffala, A. A., Omer, A. H. S., and Dietrich, M., 1981, Efficacy of metrifonate in urinary schistosomiasis in light and heavy infections, Tropenmed. Parasitol. 33:102–106.

    Google Scholar 

  • Feldmeier, H., Doehring, E., Daffala, A. A., Omer, A. H. S., and Dietrich, M., 1982, Efficacy of metrifonate in urinary schistosomiasis: Comparison of reduction of Schistosoma haematobium and S. mansoni eggs, Am.J. Trop. Med. Hyg. 31:1188–1194.

    PubMed  CAS  Google Scholar 

  • Foster, R., and Cheetham, B. L., 1973, Studies with the schistosomicide oxamniquine (UK4271) I, Trans. R. Soc. Trop. Med. Hyg. 67:674–684.

    Article  PubMed  CAS  Google Scholar 

  • Friedheim, E. A. H., 1973, Chemotherapy of schistosomiasis, in: Chemotherapy of Helminthiasis (R. Cavier and F. Hawking, eds.), pp. 29–144, Pergamon Press, Oxford.

    Google Scholar 

  • Frohberg, H., 1984, Results of toxicological studies on praziquantel, Arzneimittelforsch. 34(11): 1137–1144.

    PubMed  CAS  Google Scholar 

  • Fu, S., Zhou, X. Z., and Fan, Y., 1983, Comparative study on different dose schedules of praziquantel in the treatment of schistosomiasis japonica, J. Parasitol. Parasitic Dis. 1:32–36.

    CAS  Google Scholar 

  • Gilbert, B., DeSouza, J. P., Fortes, C. C, DosSantos, F., DoPrado Seabra, A., Kitagawa, M., and Pellegrino, J., 1970, Chemoprophylactic agents in schistosomiasis: Active and inactive terpenes, J. Parasitol. 56:397–398.

    Article  PubMed  CAS  Google Scholar 

  • Gonnert, R., and Andrews, P., 1977, Praziquantel, a new broad-spectrum antischistosomal agent, Z. Parasitenk. 52:129–150.

    Article  PubMed  CAS  Google Scholar 

  • Greene, L. K., Grenan, M. M., Davidson, D. E., Jr., Jones, D. H., and Shedd, T. R., 1983, Amoscanateas a topically applied chemical for prophylaxis against Schistosoma mansoni infections in mice, Am. J. Trop. Med. Hyg. 32:1356–1363.

    PubMed  CAS  Google Scholar 

  • Harinasuta, T., Bunnag, D., and Radomyos, P., 1984, Efficacy of praziquantel on fasciolopsiasis, Arzneimittelforsch. 34(II):1214–1215.

    Google Scholar 

  • Horstmann, R. D., Feldheim, W., Feldmeier, H., and Dietrich, M., 1981, High efficacy of praziquantel in the treatment of 22 patients with Clonorchis/Opisthorchis infections, Tropenmed. Parasitol. 32:157–160.

    PubMed  CAS  Google Scholar 

  • Ishizaki, T., Kamo, E., and Boelone, E., 1979, Double-blind studies of tolerance to praziquantel in Japanese patients with Schistosoma japonicum infection, Bull. WHO 57:787–792.

    PubMed  CAS  Google Scholar 

  • Islip, P. J., 1973, Progress in the experimental chemotherapy of helminth infections, Fortschr. Arzneimittelforsch. 17:241–319.

    CAS  Google Scholar 

  • Jackson, H., Davies, P., and Bock, M., 1968, Chemosterilization of Schistosoma mansoni, Nature (Lond.) 218:977.

    Article  CAS  Google Scholar 

  • James, C., Webbe, G., and Nelson, G. S., 1977, The susceptibility to praziquantel of Schistosoma haematobium in the baboon (Papio anubis) and of S. japonicum in the vervet monkey (Cercopithecus aethiops), Z. Parasitenk. 52:1179–1194.

    Article  Google Scholar 

  • Johnson, R. J., Dunning, S. B., Minshew, B. H., and Jong, E. C., 1983, Successful praziquantel treatment of paragonimiasis following bithionol failure, Am.J. Trop. Med. Hyg. 32:1309–1311.

    PubMed  CAS  Google Scholar 

  • Katz, N., and Pellegrino, J., 1974, Experimental chemotherapy of schistosomiasis mansoni, Adv. Parasitol. 12:369–390.

    Article  PubMed  CAS  Google Scholar 

  • Katz, N., Zicker, F., and Pereira, J. P., 1977, Field trials with oxaminiquine in schistosomiasis mansoniendemic area, Am. J. Trop. Med. Hyg. 26:234–237.

    PubMed  CAS  Google Scholar 

  • Katz, N., Rocha, R. S., and Chaves, A., 1979, Preliminary trials with praziquantel in human infections due to Schistosoma mansoni, Bull. WHO 57:781–786.

    PubMed  CAS  Google Scholar 

  • Katz, N., Rocha, R. S., and Chaves, A., 1981, Clinical trials with praziquantel in Schistosoma mansoni, Rev. Inst. Med. Trop. Sao Paulo 23:72–78.

    PubMed  CAS  Google Scholar 

  • Kern, P., Burchard, G. D., and Deitrich, M., 1984, Comparative study of oltipraz versus praziquantel for treatment of schistosomiasis with intestinal manifestation in the Gabon (Schistosoma intercalatum and S. haematobium), Tropenmed. Parasitol. 35:95–99.

    PubMed  CAS  Google Scholar 

  • Kilpatrick, M. E., El Masry, N. A., Bassily, S., and Farid, Z., 1982, Oxamniquine versus niridazole for treatment of uncomplicated Schistosoma mansoni infection, Am. J. Trop. Med. Hyg. 31:1164–1167.

    PubMed  CAS  Google Scholar 

  • Krajden, S., Keystone, J. S., and Glenn, C., 1983, Safety and toxicity of oxamniquine in the treatment of Schistosoma mansoni infections, with particular reference to electroencephalographic abnormalities, Am.J. Trop. Med. Hyg. 32:1344–1346.

    PubMed  CAS  Google Scholar 

  • Kuang, Q. H., Zhou, Y. T., Lei, S. Z., Cao, W. J., and Zhong, H. L. Chung, H. L., 1984, Clonorchiasis: Treatment with Praziquantel in 50 cases, Arzneimittelforsch. 34:(II): 1162–1163.

    PubMed  CAS  Google Scholar 

  • Lambertucci, J. R., Greco, D. B., Pedroso, E. R. P., Rocha, M. O. D., Salazar, H-M, and DeLima, D. P., 1982, A double blind trial with oxamniquine in chronic schistosomiasis mansoni, Trans. R. Soc. Trop. Med. Hyg. 76:751–755.

    Article  PubMed  CAS  Google Scholar 

  • Lammler, G., 1968, Chemotherapy of trematode infections, in: Advances in Chemotherapy (A. Goldin, F. Hawking, and R. J. Schnitzer, eds.), pp. 153–251, Academic Press, New York.

    Google Scholar 

  • Lapierre, J., Keita, A., Faurant, C., Heyer, F., Tourte-Schaefer, C., Ancelle, T., and Dupouy-Camet, J., 1983, Treatment of 700 cases of bilharziasis with the new drugs oxamniquine, oltipraz, praziquantel, Bull. Soc. Pathol. Exot. Fil. 76:526–533.

    CAS  Google Scholar 

  • Le, W. J., You, J. Q., and Mei, J. Y., 1983, Chemotherapeutic effect of artesunate in experimental schistosomiasis, Yao Hsueh Hsueh Pao 18:619–621.

    PubMed  CAS  Google Scholar 

  • Lee, S. H., 1984, Large scale treatment of Clonorchis sinensis infections with praziquantel under field conditions, Arzneimittelforsch. 34(11): 1227–1230.

    PubMed  CAS  Google Scholar 

  • Legator, M. S., Connor, T. H., and Stoeckel, M., 1975, Detection of mutagenic activity of metronidazole and niridazole in body fluids of humans and mice, Science 188:1118–1119.

    Article  PubMed  CAS  Google Scholar 

  • Mahmoud, A. A. F., Siongok, T. K. A., Ouma, J., Houser, H. B., and Warren, K. S., 1983, Effect of targeted mass treatment on intensity of infection and morbidity in schistosomiasis mansoni, Lancet 1:849–851.

    Article  PubMed  CAS  Google Scholar 

  • Mason, P. R., and Tswana, S. A., 1984, Single-dose metrifonate for the treatment of Schistosoma haematobium infection in an endemic area of Zimbabwe, Am. J. Trop. Med. Hyg. 33:599–601.

    PubMed  CAS  Google Scholar 

  • McMahon, J. E., 1976, Oxamniquine (UK4271) in Schistosoma haematobium infections, Ann. Trop. Med. Parasitol. 70:121–122.

    PubMed  CAS  Google Scholar 

  • McMahon, J. E., 1983, A comparative trial of praziquantel, metrifonate and niridazole against Schistosoma haematobium, Am. Trop. Med. Parasitol. 77:139–142.

    CAS  Google Scholar 

  • Minggang, C., Sui, F., Xiangjin, H., and Huimin, W., 1984, A retrospective survey on side effects of praziquantel among 25693 cases of schistosomiasis japonica, Southeast Asian J. Trop. Med. Publ. Health 14:495–500.

    Google Scholar 

  • Monson, M. H., Koenig, J. W., and Sachs, R., 1983, Successful treatment with praziquantel of six patients infected with the African lung fluke, Paragonimus uterobilateralis, Am.J. Trop. Med. Hyg. 32:371–375.

    PubMed  CAS  Google Scholar 

  • Muftic, M., 1970, New methods for testing schistosomicidal drugs, J. Trop. Med. Hyg. 73:232–234.

    PubMed  CAS  Google Scholar 

  • Nash, T. E., Hofstetter, M., Cheeves, A. W., and Ottesen, E. A., 1982, Treatment of Schistosoma mekongi with praziquantel: A double-blind study, Am. J. Trop. Med. Hyg. 31:977–982.

    PubMed  CAS  Google Scholar 

  • Omer, A. H. S., and Teesdale, C. H., 1978, Metrifonate trial in the treatment of various presentations of Schistosoma haematobium and Schistosoma mansoni infections in the Sudan, Ann. Trop. Med. Parasitol. 12:145–150.

    Google Scholar 

  • Pellegrino, J., and Katz, N., 1968, Experimental chemotherapy of schistosomiasis mansoni, Adv. Parasitol. 6:233–290.

    Article  PubMed  CAS  Google Scholar 

  • Pellegrino, J., and Katz, N., 1969, Experimental chemotherapy of schistosomiasis, part 4: oogram studies with nicarbazin, ang suppressive agent, Rev. Inst. Med. Trop. Sao Paulo 11:215–221.

    PubMed  CAS  Google Scholar 

  • Pellegrino, J., Lima-Costa, F. F., Carlos, M. A., and Mello, R. T., 1977, Experimental chemotherapy of schistosomiasis mansoni XIII, Z. Parasitenk. 52:151–168.

    Article  PubMed  CAS  Google Scholar 

  • Pieron, R., Mafart, Y., Lesobre, B., Grivaux, M., and Lancastre, F., 1984, L’oltipraz en traitement bref de la schistosomose à S. haematobium. Trois prises en un jour ou une seule prise, Therapie 39:167–176.

    PubMed  CAS  Google Scholar 

  • Pitchford, R. J., and Lewis, A. M., 1978, Oxamniquine in the treatment of various schistosome infections in South Africa, South Afr. Med. J. 53:677–680.

    CAS  Google Scholar 

  • Plestina, R., Davis, A., and Bailey, D. R., 1972, Effect of metrifonate on blood cholinesterases in children during the treatment of schistosomiasis, Bull. WHO 46:747–759

    Google Scholar 

  • Pugh, R. N., and Teesdale, C. H., 1984, Long-term efficacy of single-dose oral treatment in schistosomiasis haematobium, Trans. R. Soc. Trop. Med. Hyg. 78:55–59.

    Article  PubMed  CAS  Google Scholar 

  • Radomyos, P., Bunnag, D., and Harinasuta, T., 1982, Echinostoma ilocanum infection in man in Thailand, Southeast Asian J. Trop. Med. Publ. Health 13:265–269.

    CAS  Google Scholar 

  • Rim, H. J., 1973, Chemotherapy of trematode infection excluding schistosomiasis, in: Proceedings of the Tenth SEAMEO-TROPMED Seminar: Symposium on Chemotherapy in Tropical Medicine of Southeast Asia and the Far East, October 26–30, 1972, Bangkok.

    Google Scholar 

  • Rim, H. J., and Chang, Y. S., 1980, Chemotherapeutic effect of niclofolan and praziquantel in the treatment of paragonimiasis, Korea Univ. Med. J. 17:113–126.

    Google Scholar 

  • Rim, H. J., Lyu, K. S., Lee, J. S., and Koo, K. H., 1981, Clinical evaluation of therapeutic effect of praziquantel (Embay 8440) against Clonorchis sinensis infection, Ann. Trop. Med. Parasitol. 15:27.

    Google Scholar 

  • Rim, H. J., 1984, Paragonimiasis: Experimental and clinical experience with praziquantel in Korea, Arzneimittelforsch. 34(11): 1197–1203.

    PubMed  CAS  Google Scholar 

  • Ruenwongsa, P., and Thamavit, W., 1983, Increased efficacy of liposomes-Encapsulated praziquantel in treatment of opisthorchiasis in hamsters, Southeast Asian J. Trop. Med. Publ. Health 14:501–504.

    CAS  Google Scholar 

  • Saif, M., Koura, M., and Abdel-Fattah, F., 1973, The oral treatment of 5. haematobium infection with metrifonate, J. Egypt. Med. Assoc. 56:527–531.

    Google Scholar 

  • Santos, A. T., Blas, B. L., Nosenas, J. S., Portillo, G. P., Ortega, D. M., Hayashi, M., and Boehme, K., 1979, Preliminary clinical trials with praziquantel in Schistosoma japonicum infections in the Philippines, Bull. WHO 57:593–900.

    Google Scholar 

  • Santos, A. T., Blas, B. L., Portillo, G. P., Nosenas, J. S., Poliquit, O., and Papasin, M., 1984, Phase III clinical trials with praziquantel in S. japonicum infections in the Philippines, Arzneimittelforsch. 34(II):1221–1223.

    PubMed  CAS  Google Scholar 

  • Sleigh, A. C., Mott, K. E., and Franca Silva, J. T., 1981, A three–year follow-up of chemotherapy with oxamniquine in a Brazilian community with endemic schistosomiasis, Trans. R. Soc. Trop. Hyg. 75:234–238.

    Article  CAS  Google Scholar 

  • Soh, C. T., 1984, Clonorchis sinensis: Experimental and clinical studies with praziquantel in Korea, Arzneimittelforsch. 34(II): 1156–1159.

    PubMed  CAS  Google Scholar 

  • Sornmani, S., Schelp, F. P., Vivatanasesth, P., Patihatakorn, W., Impand, P., Sitabutra, P., Worasan, P., and Preuksaraj, S., 1984, A pilot project for controlling O. viverrini infection in Nong Wai, Northeast Thailand, by applying praziquantel and other measures, Arzneimittelforsch. 34(11): 1231–1234.

    PubMed  CAS  Google Scholar 

  • Spitalny, K. C., Senft, A. W., Meglio, F. D., Morgan, J., and Peter, G., 1982, Treatment of pulmonary paragonimiasis with a new broad-spectrum anthelmintic, praziquantel, J. Pediatr. 101:144–146.

    Article  PubMed  CAS  Google Scholar 

  • Standen, O. D., 1963, Chemotherapy of helminthic infections, in: Experimental Chemotherapy (R. J. Schnitzer and F. Hawking, eds.), Vol. 1, pp. 701–892, Academic Press, New York and London.

    Google Scholar 

  • Supanvanich, S., Supavonich, K., and Pawabut, P., 1981, Field trial of praziquantel in human opisthorchiasis in Thailand, Southeast Asian J. Trop. Med. Publ. Health 12:598–602.

    CAS  Google Scholar 

  • Vanijanonta, S., Bunnag, D., and Harinasuta, T., 1984, Paragonimus heterotremus and other Paragonimus spp. in Thailand: Pathogenesis, clinic and treatment, Arzneimittelforsch. 34(11): 1186–1188.

    PubMed  CAS  Google Scholar 

  • Warren, K. S., 1970, Suppression of hepatosplenic schistosomiasis mansoni in mice by nicarbazin, a drug that inhibits egg production by schistosomes, J. Infect. Dis. 121:514–521.

    Article  PubMed  CAS  Google Scholar 

  • Warren, K. S., and Mahmoud, A. A. F., 1976, Targeted mass treatment. A new approach to the control of schistosomiasis, Trans. Assoc. Am. Physicians 89:195–204.

    PubMed  CAS  Google Scholar 

  • Webbe, G., and James, C., 1977, A comparison of the susceptibility of praziquantel of Schistosomahaematobium, S. japonicum, S. mansoni, S. intercalatum and S. mattheei in hamsters, Z. Parasitenk. 52:169–177.

    Article  PubMed  CAS  Google Scholar 

  • Webbe, G., and Jordan, P., 1982, Control, in: Schistosomiasis (P. Jordan and G. Webbe, eds.), pp. 293–349, Heinemann Medical Books, London.

    Google Scholar 

  • Wegner, D. H. G., 1984, The profile of the trematodicidal compound praziquantel, Arzneimittelforsch. 34(11): 1132–1136.

    PubMed  CAS  Google Scholar 

  • Wykoff, D. E., 1958, Studies on Clonorchis sinensis. III, J. Parasitol. 44:461–466.

    Article  PubMed  CAS  Google Scholar 

  • Yokogawa, M., 1984, Experimental chemotherapy of paragonimiasis, Arzneimittelforsch. 34(11): 1193–1196.

    PubMed  CAS  Google Scholar 

  • Yoshida, Y., Miyaké, T., Nakaniski, Y., Nishido, K., Yamanashi, Y., Ishikawa, T., Fujisoka, K., Tanaka, A., and Embara, S., 1962, Cases of human infection with Fasciola sp. and treatment with Bithionol, Jpn.J. Parasitol. 11:41–43.

    Google Scholar 

  • Zhou, G. X., 1983, Clinical observation on schistosomiasis japonica treated with amoscanate and phenithionate in a hyperendemic area, Chung Hua Nei Ko Tsa Chih 22:634–645

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Plenum Press, New York

About this chapter

Cite this chapter

Campbell, W.C., Garcia, E.G. (1986). Trematode Infections of Man. In: Campbell, W.C., Rew, R.S. (eds) Chemotherapy of Parasitic Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1233-8_19

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-1233-8_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1235-2

  • Online ISBN: 978-1-4684-1233-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics