Skip to main content

Nematode Infections of Man: Intestinal Infections

  • Chapter
Chemotherapy of Parasitic Diseases

Abstract

In most underdeveloped regions of the world, especially the tropical areas, intestinal helminthiases present high prevalence rates, similar to those found a half-century ago (Botero, 1981). The varied and sometimes important symptomatology caused by these worms, the lowering of work efficiency, and the deterioration of nutritional status are deleterious consequences requiring efficient confrontation not only by traditional measures such as installation of latrines, potable water, wearing of shoes, instruction, and personal hygiene, but also by medical treatment to individuals or to affected populations.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Amato Neto, V., Sinto, T., Pedro, R.J., Levi, G.C., Tsukumo, M.K.K., de Moraes, V.M.C., and Correa, L. de L., 1978, Nossas observacoes iniciais sobre a eficacia do cambendazole no tratamento da estrongiloidiase, Rev. Inst. Med. Trop. 20:161–163.

    CAS  Google Scholar 

  • Amato-Neto, V., Moreira, A.A.B., Campos, R., Lazzaro, E.S.M., Chiaramelli, M.C.G., Pinto, P.L.S., Da Silva, G.R., Nishioka, S., and de A. e Leite, R.M., 1983, Tratamento da ancilostomiase, ascaridiase e tricocefaliase por mejo do albendazol ou do mebendazol, Rev. Inst. Med. Trop. 25:294–299.

    CAS  Google Scholar 

  • Baransky, M.C., Silva, A.F., Kotaka, P.I., Gomez, N.R., Giovannoni, M., and Telles, J.E.Q., 1978, Tratamento da estrongiloidiase humana com novo antihelmintico, o cambendazole. Estudo duplo cego, Rev. Inst. Med. Trop. Sao Paulo 20:213–218.

    Google Scholar 

  • Beck, J.W., Saavedra, D., Anteil, G.J., and Tejeiros, B., 1959, The treatment of pinworm infections in humans (enterobiasis) with pyrvinium chloride and pyrvinium pamoate, Am.J. Trop. Med. Hyg. 8:349–352.

    PubMed  CAS  Google Scholar 

  • Botero, C.A., Calad, G.A., Cardona, E.A., Correa, D.H., and Gonzalez, C.M., 1984, Epidemiologia de las helmintiasis intestinales en una zona rural de Antioquia, Colombia (Control por tratamiento comunitario), Medicina Universidad Pontificia Bolivariana 3:65–76.

    Google Scholar 

  • Botero, D., 1976, Clinical trial methodology in intestinal parasitic disease, Clin. Pharmacol. Ther. 19:630–637.

    PubMed  CAS  Google Scholar 

  • Botero, D., 1979, Posibilidades de control de las geohelmintiasis mediante tratamientos en masa, Bol. Chile. Parasitol. 34:39–43.

    CAS  Google Scholar 

  • Botero, D., 1981, Persistence of the endemic intestinal parasitoses in Latin America, Bull. Pan. Am. Health Org. 15:241–248.

    CAS  Google Scholar 

  • Botero, D., and Castano, A., 1973, Comparative study of pyrantel pamoate, bephenium hydroxinaphthoate and tetrachloroethylene in the treatment of Necator americanus infections, Am.J. Trop. Med. Hyg. 22:45–52.

    PubMed  CAS  Google Scholar 

  • Brugmans, J.P., Thienpont, D.C., Van Wijngaarden, I., Vanparijs, O.F., Schermans, V.L., and Lauwers, H.L., 1971, Mebendazole in enterobiasis. Radio-chemical and pilot clinical study in 1,278 subjects, J.A.M.A. 217:313–316.

    Article  PubMed  CAS  Google Scholar 

  • Campbell, W.C., and Cuckler, A.C., 1969, Thiabendazole in the treatment and control in parasitic infections in man, Tex. Rep. Biol. Med. (Suppl. 2) 27:665–692.

    Google Scholar 

  • Calvalho Filho, E., 1978, Strongyloidiasis. Clin. Gastroenterol. 7:179–200.

    Google Scholar 

  • Chitchang, S., Leelayoova, S., and Piamjinda, T., 1983, Albendazole in the treatment of hookworm infestation in Thailand, J. Med. Assoc. Thailand 66:45–48.

    CAS  Google Scholar 

  • Coulaud, J.P., Deluol, A.M., Cenac, J., and Rossignol, J.F., 1982, L’albendazole dans le traitement de la strongyloidose: à propos de 66 observations, Bull. Soc. Pathol. Exot. Fil. 75:530–533.

    CAS  Google Scholar 

  • Davis, A., 1973, Drug Treatment of Intestinal Helminthiases, 125 pp., World Health Organization, Geneva.

    Google Scholar 

  • Firth, M. (ed.), 1983, Albendazole in helminthiasis, in: International Congress Symposium Series, No. 57, Royal Society of Medicine, London.

    Google Scholar 

  • Goodwin, L.G., 1980, New drugs for old diseases, Trans. R. Soc. Trop. Med. Hyg. 74:1–7.

    Article  PubMed  CAS  Google Scholar 

  • Grove, D.I., 1982, Strongyloides ratti and S. stercoralis: The effects of thiabendazole, mebendazole and cambendazole in infected mice, Am. J. Trop. Med. Hyg. 31:469–476.

    PubMed  CAS  Google Scholar 

  • Grove, D.I., 1983, The effects of 22,23-dihydroavermectin B1 on Strongyloides ratti and S. stercoralis infections in mice, Ann. Trop. Med. Parasitol. 77:405–410.

    PubMed  CAS  Google Scholar 

  • Kan, S.P., 1983, The anthelmintic effects of flubendazole on Trichuris trichiura and Ascaris lumbricoides, Trans. R. Soc. Trop. Med. Hyg. 77:668–670.

    Article  PubMed  CAS  Google Scholar 

  • Lee, E.L., Kyngkaran, N., Grieve, A.W., Robinson, M.J., and Dissanaike, A.S., 1976, Therapeutic evaluation of oxantel pamoate (l,4,5,6-tetrahydro-l-methyl-2-(trans-3-hydroxystyryl)pyrimidine pamoate) in severe Trichuris trichiura infection, Am. J. Trop. Med. Hyg. 25:563–567.

    PubMed  CAS  Google Scholar 

  • Moens, M., Dom, J., Burke, W.E., Schlossberg, S., and Schermans, V., 1978, Levamisole in ascariasis. A multicenter controlled evaluation, Am. J. Trop. Med. Hyg. 27:897–904.

    PubMed  CAS  Google Scholar 

  • Pawlowski, Z.S., 1983, Clinical aspects in man, in: Trichinella and Trichinosis (W. C. Campbell, ed.), pp. 367–401, Plenum Press, New York.

    Chapter  Google Scholar 

  • Peña-Chavarria, A., Swatzwelder, J.C., Villarejos, V.M., and Zeledon, R., 1973, Mebendazole an effective broad spectrum anthelmintic, Am. J. Trop. Med. Hyg. 22:592–595.

    Google Scholar 

  • Pene, P., Mojon, M., Garin, J.P., Coulaud, J.P., and Rossignol, J.F., 1982, Albendazole: a new broad spectrum anthelmintic. Double blind multicenter clinical trial, Am. J. Trop. Med. Hyg. 31:263–266.

    PubMed  CAS  Google Scholar 

  • Renoux, G., Renoux, M., Teller, M.N., McMahon, S., and Gyillaumin, J.M., 1976, Potentiation of Tcell mediated immunity by levamisole, Clin. Exp. Immunol. 25:288–296.

    PubMed  CAS  Google Scholar 

  • Rossignol, J.F., and Coulaud, J.P., 1983, Summary of clinical trials worldwide (evaluation of albendazole in Europe, West Africa and Asia as a single-dose anthelmintic: report on 1455 patients), in: Albendazole in Helminthiasis (M. Firth, ed.), International Congress Symposium Series, No. 57, Royal Society of Medicine, London, pp. 19–27.

    Google Scholar 

  • Rossignol, J.F., and Maisonneuve, H., 1983, Albendazole: Placebo-controlled study in 870 patients with intestinal helminthiasis, Trans. R. Soc. Trop. Med. Hyg. 17:707–711.

    Article  Google Scholar 

  • Sanati, A., and Ghadirian, E.G., 1971, Treatment of enterobiasis with pyrantel pamoate in Iran, J. Trop. Med. Hyg. 74:160–161.

    PubMed  CAS  Google Scholar 

  • Sargent, R.G., Savory, A.M., Mina, A., and Lee, P.R., 1974, A clinical evaluation of mebendazole in the treatment of trichuriasis, Am. J. Trop. Med. Hyg. 23:375–377.

    PubMed  CAS  Google Scholar 

  • Schenone, H., Galdames, M., Insunza, E., Jimenez, M., Romero, E., and Bloomfield, R., 1977, Flubendazol en el tratamiento de infecciones por nematodes intestinales en niños, Bol. Chil. Parasitol. 32:85–86.

    PubMed  CAS  Google Scholar 

  • Stephenson, L.S., Cromptom, E.W.T., Latham, M.C., Arnold, S.E., and Jansen, A.A.J., 1983, Evaluation of a four year project to control Ascaris infection in children in two Kenyan villages, J. Trop. Pediatr. 29:175–184.

    PubMed  CAS  Google Scholar 

  • Sturchler, D., 1982, Chemotherapy of human intestinal helminthiases: A review, with particular reference to community treatment, Adv. Pharmacol. Chemother. 19:129–154.

    Article  PubMed  CAS  Google Scholar 

  • Thienpont, D., Brugmans, J., Abadi, K., and Tanamal, S., 1969, Tetramisole in the treatment of nematode infections of man, Am. J. Trop. Med. Hyg. 18:520–525.

    PubMed  CAS  Google Scholar 

  • Van den Bossche, H., 1981, Peculiar targets in anthelmintic chemotherapy, Biochem. Pharmacol. 29:1981–1990.

    Article  Google Scholar 

  • Van den Bossche, H., Rochette, F., and Horig, C., 1982, Mebendazole and related anthelmintics, Adv. Pharmacol, and Chemother. 19:67–128.

    Article  Google Scholar 

  • Wilson, K.H., and Kauffman, C.A., 1983, Persistent Strongyloides stercoralis in a blind loop of the bowel: successful treatment with mebendazole, Arch. Intern. Med. 143:357–358.

    Article  PubMed  CAS  Google Scholar 

  • World Health Organization, 1981, Intestinal Protozoan and Helminthic Infections, Technical Report Series 666, World Health Organization, Geneva.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Plenum Press, New York

About this chapter

Cite this chapter

Botero, D. (1986). Nematode Infections of Man: Intestinal Infections. In: Campbell, W.C., Rew, R.S. (eds) Chemotherapy of Parasitic Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1233-8_12

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-1233-8_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1235-2

  • Online ISBN: 978-1-4684-1233-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics