Abstract
Ferrari (1957) was the first to report a decrease of glutamate levels in the whole brain of thiamine-deficient rats. Glutamate levels were also reduced in the brains of pyrithiamine-treated mice (Holowach et al., 1968). Subsequently, decreases in threonine, γ-aminobutyrate (GABA), aspartate, and serine and increases in glycine were also seen in the brains of thiamine-deprived animals and/or of those treated with pyrithiamine (Gaitonde and Nixey, 1974; Gabler et al., 1974; Gaitonde and Fayein, 1975).
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© 1985 Plenum Press, New York
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Thurston, J.H., Hauhart, R.E., Dirgo, J.A., McDougal, D.B. (1985). Thiamine Deficiency. In: McCandless, D.W. (eds) Cerebral Energy Metabolism and Metabolic Encephalopathy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1209-3_15
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DOI: https://doi.org/10.1007/978-1-4684-1209-3_15
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