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Stress and Secondary Metabolism in Cultured Plant Cells

  • Chapter
Phytochemical Adaptations to Stress

Part of the book series: Recent Advances in Phytochemistry ((RAPT,volume 18))

Abstract

Grime1 defines “stress” in plants as the external constraints which limit the rate of dry matter production of all or part of the vegetation, e.g. shortages of water, light, mineral nutrients and suboptimal temperatures. These shortages may be an inherent characteristic of the environment, or they may be induced or intensified by the vegetation itself. The use of the word “stress” to describe an external constraint on dry matter production differs from that of many plant physiologists however, who have used the word to describe the physiological state of the plant. Grime’s definition could be applied to cultured plant cells; stress in this case would be any type of constraint which reduces the dry matter of the cultures. This otherwise excellent and precise definition is not very useful, however, to phytochemists who are generally not interested in dry matter production. We will define stress as the external constraints on cultured cells which limit the normal production of secondary metabolites. Let us call this phytochemical stress to be absolutely specific.

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References

  1. Grime JP 1981 Plant Strategies In Shade. In Plants And The Daylight Spectrum (H Smith, ed) Academic Press New York pp. 159–186

    Google Scholar 

  2. Dixon RA, KW Fuller 1976 Effects Of Synthetic Auxin Levels On Phaseollin Production And Phenylalanine Ammonia Lyase ( PAL) activity in tissue cultures of Phaseolus vulgaris L. Physiol Plant Pathol 9: 299–312

    Article  Google Scholar 

  3. Gustine DL 1981 Evidence For Sulfydryl Involvement In Regulation Of Phytoalexin Accumulation In Trifolium Repens Callus Tissue Cultures. Plant Physiol 68: 1323–1326

    Article  Google Scholar 

  4. Reilley JJ, WL Klarman 1980 Thymine Dimer And Glyceollin Accumulation In U. V. -Irradiated Soybean Suspension Cultures. Environ Exp Bot 20: 131–134

    Article  Google Scholar 

  5. Gafni Y, I Shechter 1981 Diethylene Glycol Disulfide From Castor Bean Cell Suspension Cultures. Phytochemistry 20: 2477–2479

    Article  Google Scholar 

  6. Doller G, AW Alferman, E Reinhard 1976 Production Of Indole Alkaloids In Tissue Cultures Of Catharanthus Roseus. Planta Med 30: 14–20

    Article  Google Scholar 

  7. Tabata M, N Hiraoka 1976 Variation Of Alkaloid Production In Nicotiana Rustica Callus Cultures. Physiol Plant 38: 19–23

    Article  Google Scholar 

  8. Tanaka H, Y Machida, H Tanaka, N Mukai, M Misawa 1974 Accumulation Of Glutamine By Suspension Cultures Of Symphytum Officinale. Agric Biol Chem 38: 987–992

    Article  Google Scholar 

  9. Watanabe K, S-I Yano, Y Yamada 1982 The Selection Of Cultured Plant Cell Lines Producing High Levels Of Biotin. Phytochemistry 21: 513–516

    Article  Google Scholar 

  10. Zenk MH, H El-Shagi, U Sghulte 1975 Anthraquinone Production By Cell Suspension Cultures Of Morinda Citrifolia. Planta Med Suppl 79: 79–101

    Article  Google Scholar 

  11. Zenk MH, H El-Shagi, H Arens, H Stockigt, EW Weiler, B Deus 1977 Formation Of The Indole Alkaloids Serpentine And Ajmalicine In Cell Suspension Cultures Of Catharanthus Roseus. In Plant Tissue Culture And Its Bio-Technological Application ( W. Barz, W. Reinhard, M. H. Zenk, eds) Springer-Verlag, Berlin, New York, pp. 27–43

    Chapter  Google Scholar 

  12. Ellis BE 1980 Accumulation Of Hydroxyphenylethanol Glucosides In Cultured Cells Of Syringa Vulgaris. Hoppe Seyler1 S Z. Physiol. Chem. 361: 242

    Google Scholar 

  13. Berlin J, KH Knobloch 1980 Biochemical Characterization Of A Variant Tobacco Cell Line Accumulating High Levels Of Cinnamoyl Putrescine Derivatives. Hoppe Seylerfs Z Physiol Chem 361: 219–220

    Google Scholar 

  14. Bergman L, H Rennenberg 1978 Efflux Und Production Von Glutathion In Suspensiokulturen Von Nicotiana Tabacum. Z Pflanzenphysiol 88: 175–185

    Google Scholar 

  15. Radwan SS, CK Kokate 1980 Production Of Higher Levels Of Trigonelline By Cell Cultures Of Trigonella Foenum Graecum Than By The Differentiated Plant. Planta 147: 340–344

    Article  Google Scholar 

  16. Staba EJ, B Kaul 1971 Production Of Diosgenin By Plant Tissue Culture Technique. Us Patent 3,628, 287

    Google Scholar 

  17. Furuya T, T Yoshikawa, H Kiyohara 1983 Alkaloid Production In Cultured Cells Of Dioscoreophyllum Cumminsii. Phytochemistry 22: 1671–1673

    Article  Google Scholar 

  18. Fujita Y, Y Maeda, C Suga, T Morimoto 1983 Production Of Shikonin Derivatives By Cell Suspension Cultures Of Lithospermum Erythrorhizon. Ill Comparison Of Shikonin Derivatives Of Cultured Cells And Ko-Shikon. Plant Cell Reports 2: 192–193

    Article  Google Scholar 

  19. Akasu M, H Itokawa, M Fujita 1976 Biscolaurine Alkaloids In Callus Tissues Of Stephania Cepharantha. Phytochemistry 15: 471–473

    Article  Google Scholar 

  20. Butcher DN, JD Connolly 1971 An Investigation Of Factors Which Influence The Production Of Abnormal Terpenoids By Callus Cultures Of Andrographis Paniculata Nees. J Exp Bot 22: 314–322

    Article  Google Scholar 

  21. Delfel NE, JA Rothfus 1977 Antitumor Alkaloids In Callus Cultures Of Cephalotaxus Harringtonia. Phytochemistry 16: 1595–1598

    Article  Google Scholar 

  22. Stockigt J, J Treimer, MH Zenk 1976 Synthesis Of Ajmalicine And Related Indole Alkaloids By Cell Free Extracts Of Catharanthus Roseus Cell Suspensions. Febs Lett 70: 267–270

    Article  Google Scholar 

  23. Neumann D, E Muller 1971 Beiträge Zur Physiologie Der Alkaloide. V. Alkaloidbildung In Kallus-Und Suspensionskulturen Von Nicotiana Tabacum L. Biochem Physiol Pflanzen 162: 503–513

    Google Scholar 

  24. Tabata M, M Tsukuda, H Fukui 1982 Antimicrobial Activity Of Quinone Derivatives From Echium Lycopsis Callus Cultures. Planta Med 44: 234–236

    Article  Google Scholar 

  25. Arens H, HO Borbe, B Ulbrich, J Stockigt 1982 Detection Of Pericine, A New Cns-Active Indole Alkaloid From Picralima Nitida Cell Suspension Culture By Opiate Receptor Binding Studies. Planta Med 46: 210–214

    Google Scholar 

  26. Barz W, E Reinhard, MH Zenk (eds) 1977 Plant Tissue Culture and its Bio-technological Application. Springer-Verlag, Berlin, New York, 419 pp

    Google Scholar 

  27. Carew DP, RJ Krueger 1977 Catharanthus Roseus Tissue Culture: The Effects Of Medium Modifications On Growth And Alkaloid Production. J Nat Prod 4: 326–336

    Google Scholar 

  28. Dicosmo F, RA Norton, GHN Towers 1982 Fungal Culture-Filtrate Elicits Aromatic Polyacetylenes In Plant Tissue Culture. Naturwissenschaften 69: 550–551

    Article  ADS  Google Scholar 

  29. Fleck J, A Durr, MC Lett, L Hirth 1979 Changes In Protein Synthesis During The Initial Stage Of Life Of Tobacco Protoplasts. Planta 145: 279–285

    Article  Google Scholar 

  30. Fleck J, A Durr, C Fritsch, MC Lett, L Hirth 1980 Comparison Of Proteins Synthesized In Vivo And In Vitro By Mrna From Isolated Protoplasts. Planta 148: 453–454

    Google Scholar 

  31. Kurz WGW, F Constabel 1979 Plant Cell Cultures, A Potential Source Of Pharmaceuticals. Adv Appl Microbiol 25: 209–240

    Article  Google Scholar 

  32. Radwan, SS, F Spener, HK Mangold, F Staba 1975 Lipids In Plant Tissue Cultures. Iv. The Characteristic Patterns Of Lipid Classes In Callus Cultures And Suspension Cultures. Chem Phys Lipids 14: 72–80

    Google Scholar 

  33. Reinert J, YPS Bajaj (eds) 1977 Applied and Fundamental Aspects of Plant Cell, Tissue and Organ Culture. Springer-Verlag, Berlin, New York, 716 pp

    Google Scholar 

  34. Steck W, BK Bailey, JP Shyluk, OL Gamborg 1971 Coumarins And Alkaloids From Cell Cultures Of Ruta Graveolens. Phytochemistry 10: 191–194

    Article  Google Scholar 

  35. Halder T, VN Gadgil 1983 Fatty Acids Of Callus Tissues Of Six Species Of Curcurbitaceae. Phytochemistry 22: 1965–1967

    Article  Google Scholar 

  36. Hirotani M, T Furuya 1977 Restoration Of Cardenolide Synthesis In Redifferentiated Shoots From Callus Cultures Of Digitalis Purpurea. Phytochemistry 16: 610–611

    Article  Google Scholar 

  37. Ebel J, AR Ayers, P Albersheim 1971 Host-Pathogen Interactions Xii. Response Of Suspension-Cultured Soybean Cells To The Elicitor Isolated From Phytophthora Megasperma Var. Sojae, A Fungal Pathogen Of Soybeans. Plant Physiol 57: 775–779

    Google Scholar 

  38. Ebel J, K Hahlbrock 1977 Enzymes Of Flavone And Flavonol-Glycoside Biosynthesis. Coordinated And Selective Induction In Cell-Suspension Cultures Of Petroselinum Hortense. Eur J Biochem 75: 201–209

    Google Scholar 

  39. Hargreaves JA, C Selby 1978 Phytoalexin Formation In Cell Suspensions Of Phaseolus Vulgaris In Response To An Extract Of Bean Hypocotyls. Phytochemistry 17: 1099–1102

    Article  Google Scholar 

  40. Doke N, K Tomiya 1980 Effect Of Hyphal Wall Components From Phytophthora Infestans On Protoplasts Of Potato Tuber Tissues. Physiol Plant Pathol 16: 169–176

    Article  Google Scholar 

  41. Dixon RA, PM Dey, DL Murphy, IM Whitehead 1981 Dose Responses For Colletotrichum 1Indemuthianum Elicitor-Mediated Enzyme Induction In French Bean Cell Suspension Cultures. Planta 151: 272–280

    Article  Google Scholar 

  42. Hahlbrock K, CJ Lamb, C Purwin, J Ebel, E Fautz, E Schäfer 1981 Rapid Responses Of Suspension-Cultured Parsley Cells To The Elicitor From Phytophthora Megasperma Var. Sojae. Plant Physiol 67: 768 773

    Google Scholar 

  43. Kurz WGW, F Constabel 1979 Plant Cell Suspension Cultures And Their Biosynthetic Potential. In Microbial Technology Vol 1 (H. J. Peppier, D. Perlman, eds), Academic Press, New York, San Francisco, London, pp 389–416

    Google Scholar 

  44. Butcher DN 1977 Secondary Products In Tissue Cultures. In Plant Cell, Tissue, And Organ Culture ( J. Reinert, YPS Bajaj eds), Springer-Verlag, Berlin, pp. 668–693

    Google Scholar 

  45. Zaprometov MN 1978 Enzymology And Regulation Of The Synthesis Of Polyphenols In Cultured Cells. In Frontiers Of Plant Tissue Culture 1978 ( TA Thorpe ed), International Association for Plant Tissue Culture, Calgary pp 335–343

    Google Scholar 

  46. Alfermann AW, E Reinhard Eds 1978 Production Of Natural Compounds By Cell Culture Methods. Gesellschaft Fur Strahlen Und Umweltforschung Mbh, Munich. 361 Pp

    Google Scholar 

  47. Staba EJ Ed 1980 Plant Tissue Culture As A Source Of Biochemicals. Crc Press, Boca Raton, Florida, 285 Pp

    Google Scholar 

  48. Schüler ML 1981 Production Of Secondary Metabolites From Plant Tissue-Culture-Problems And Prospects. Ann Ny Acad Sci 369: 65–79

    Article  ADS  Google Scholar 

  49. Barz W, BE Ellis 1981 Potential Of Plant Cell Cultures For Pharmaceutical Production. In Natural Products As Medicinal Agents. ( JL Beal, E Reinhard eds) Hippokrates-Verlag, Stuttgart, pp 471–507

    Google Scholar 

  50. Bohm H 1980 The Formation Of Secondary Metabolites In Plant Tissue And Cell Cultures. Int Rev Cytol Suppl 11B: 183–208

    Article  Google Scholar 

  51. Ellis BE Selection Of Chemically-Variant Plant Cell Lines For Use In Industry In Applications Of Plant Cell And Tissue Culture To Agriculture And Industry (D Tomes, B Ellis, P Harney, K Kasha, RL Peterson eds) University of Guelph, Guelph, pp 63–80

    Google Scholar 

  52. Knobloch KH, G Bast, J Berlin 1982 Medium-And Light-Induced Formation Of Serpentine And Anthocyanins In Cell Suspension Cultures Of Catharanthus Roseus. Phytochemistry 21: 591–594

    Article  Google Scholar 

  53. Tal B, J Gressel, I Goldberg 1982 The Effect Of Medium Constituents On Growth And Diosgenin Production By Dioscorea Deltoidea Cells Grown In Batch Cultures. Planta Med 44: 111–115

    Article  Google Scholar 

  54. Davies ME 1972 Polyphenol Synthesis In Cell Suspension Cultures Of Paul’s Scarlet Rose. Planta 104: 50–65

    Article  Google Scholar 

  55. Westcott RJ, GG Henshaw 1976 Phenolic Synthesis And Phenylalanine Ammonia-Lyase Activity In Suspension Cultures Of Acer Pseudoplatanus L. Planta 131: 67–73

    Article  Google Scholar 

  56. Constabel F 1968 Gerbstoffproduktion Der Calluskulturen Von Juniperus Communis L. Planta 79: 58–64

    Article  Google Scholar 

  57. Mizukami H, M Konashima, M Tabata 1977 Effect Of Nutritional Factors On Shikonin Derivative Formation In Lithospermum Callus Cultures. Phytochemistry 16: 1183–1186

    Article  Google Scholar 

  58. Matsumoto T, K Nishida, M Noguchi, E Tamaki 1973 Some Factors Affecting The Anthocyanin Formation By Populus Cells In Suspension Culture. Agric Biol Chem 37: 561–567

    Article  Google Scholar 

  59. Amorin HB, DK Dougall, WR Sharp 1977 The Effect Of Carbohydrate And Nitrogen Concentration On Phenol Synthesis In Paul’s Scarlet Rose Cells Grown In Tissue Culture. Physiol Plant 39: 91–95

    Article  Google Scholar 

  60. Ikeda T, T Matsumoto, M Noguchi 1976 Effects Of Nutritional Factors On The Formation Of Ubiquinone By Tobacco Plant Cells In Suspension Culture. Agric Biol Chem 40: 1765–1770

    Article  Google Scholar 

  61. Gras M, J Creche, JC Chenieux, M Rideau 1982 Etude Comparee Des Effects De Al Selection Et Des Facteurs De L’environnement Sur L’accumulation Alcoloidique Des Souches De Choisya Ternata. Planta Med 46: 231–235

    Article  Google Scholar 

  62. Abe S, Y Ohta 1983 Lunularic Acid In Cell Suspension Cultures Of Marchantia Polymorpha. Phytochemistry 22: 1917–1920

    Article  Google Scholar 

  63. Nag Tn, P Khanna 1973 Effect Of Phenylalanine And Glucose On Growth And Phyllemblin Production In Emblica Officinalis Gaertn Tissue Cultures. Indian J Pharm 35: 154–155

    Google Scholar 

  64. Kadkade PG 1982 Growth And Podophyllotoxin Production In Callus Tissue Of Podophyllum Peltatum. Plant Sci Lett 25: 107–115

    Article  Google Scholar 

  65. Hess D, G Leipoldt, RD Illg 1979 Investigations On The Lactose Induction Of B-Galactosidase Activity In Callus Tissue Cultures Of Nemesia Strumosa And Petunia Hybrida. Pflanzenphysiol 94: 45–53

    Google Scholar 

  66. Nettleship L, M Slaytor 1974 Adaption Of Peganum Harmala Callus To Alkaloid Production. J Exp Bot 25: 114–123

    Article  Google Scholar 

  67. Takayama S, M Misawa, K Ko, T Misato 1977 Effect Of Cultural Conditions On The Growth Of Agrostemma Githago Cells In Suspension Culture And The Concomitant Production Of An Anti-Plant Virus Substance. Physiol Plant 41: 313–320

    Article  Google Scholar 

  68. Doller G 1978 Influence Of The Medium On The Production Of Serpentine By Suspension Cultures Of Catharanthus Roseus (L) G Don. In Production of Natural Compounds by Cell Culture Methods ( AW Alfermann, E Reinhard, eds). Gesellschaft für Strahlen-und Umweltforschung mbH, Munich pp 109–116

    Google Scholar 

  69. Knobloch K-H, J Berlin 1980 Influence Of Medium Composition On The Formation Of Secondary Compounds In Cell Suspension Cultures Of Catharanthus Roseus (L) G. Don. Z. Naturforsch 35 (c): 551–556

    Google Scholar 

  70. Carew Dp, RJ Kreuger 1976 Anthocyanidins Of Catharanthus Roseus Callus Cultures. Phytochemistry 15: 442

    Article  Google Scholar 

  71. Zenk MH, H El-Shagi, B Ulbrich 1977 Production Of Rosmarinic Acid By Cell-Suspension Cultures Of Coleus Blumei. Naturwissenschaften 64: 585–586

    Article  ADS  Google Scholar 

  72. Bauch H-J, E Leistner 1978 Aromatic Metabolism In Cell Suspension Cultures Of Galium Mullugo. Planta Med 33: 105–123

    Article  Google Scholar 

  73. Knobloch K-H, G Beutnagel, J Berlin 1981 Influence Of Accumulated Phosphate On Culture Growth And Formation Of Ciimamoyl Putrescines In Medium-Induced Cell Suspension Cultures Of Nicotiana Tabacum. Planta 153: 582–585

    Article  Google Scholar 

  74. Chandler SF, JH Dodds 1983 The Effect Of Phosphate, Nitrogen And Sucrose On The Production Of Phenolics And Solasodine In Callus Cultures Of Splanum Laciniatum. Plant Cell Reports 2: 205–208

    Google Scholar 

  75. Ravishankar GA, AR Mehta 1979 Control Of Ecdysterone Biogenesis In Tissue Cultures Of Trianthema Portulacustrum. J Nat Prod 42: 152–158

    Article  Google Scholar 

  76. Okazaki M, F Hino, K Nagasawa, Y Miura 1982 Effects Of Nutritional Factors On Formation Of Scopoletin And Scopolin In Tobacco Tissue Cultures. Agric Biol Chem 46: 601–607

    Article  Google Scholar 

  77. Edleman J, AD Hanson 1971 Sucrose Suppression Of Chlorophyll Synthesis In Carrot Callus Cultures. Planta 98: 150–156

    Article  Google Scholar 

  78. Jaspars EM, H Verdstra 1965 An A-Amylase From Tobacco Crown-Gall Tissue Cultures Ii. Measurement Of The Activity In Media And Tissues. Physiol Plant 18: 626–634

    Google Scholar 

  79. Karstens WHK, V De Meester-Manger Cats 1960 The Cultivation Of Plant Tissues In Vitro With Starch As A Source Of Carbon. Acta Bot Neer 9: 263–274

    Google Scholar 

  80. Matsumoto T, K 0Kunishi, K Nishida, M Noguchi, E Tamaki 1971 Studies On The Culture Conditions Of Higher Plant Cells In Suspension Culture. Part Ii. Effect Of Nutritional Factors On The Growth. Agric Biol Chem 35: 543–551

    Google Scholar 

  81. Mitchell ED, BB Johnston, T Whittle 1980 8-Galactosidase Activity In Cultured Cotton Cells: A Comparison Between Cells Grown On Sucrose And Lactose. In Vitro 16: 907–912

    Google Scholar 

  82. Chaubet N, V Eliard, A Pareilleux 1981 8-Galactosidases Of Suspension Cultured Medicago Sativa Cells Growing On Lactose. Plant Sci Lett 22: 369–378

    Google Scholar 

  83. Chaubet N, A Pareilleux 1982 Characterization Of B-Galactosidases Of Medicago Sativa Suspension-Cultured Cells Growing Octose. Effect Of The Growth Substrates On The Activities. Z Pflanzenphysiol 106: 401–407

    Google Scholar 

  84. Sacher JA, KT Glasziou 1962 Regulation Of Invertase Levels In Sugar Cane By Auxin-Carbohydrate Mediated Control System. Biochem Biophys Res Commun 8: 280–282

    Article  Google Scholar 

  85. Demain AL 1968 Regulatory Mechanisms And The Industrial Production Of Microbial Metabolites. Lloydia 31: 395–418

    Google Scholar 

  86. Drew SW, AL Demain 1977 Effect Of Primary Metabolites On Secondary Metabolism. Ann Rev Microbiol 31: 343–356

    Article  Google Scholar 

  87. Jindal HK, VS Bansal, C Kasinathan, S Larroya, GK Khuller 1983 Effect Of Carbon Sources On The Polar Lipid Fatty Acids Of Microsporum Gypseum Grown At Different Temperatures. Experientia 39: 151–153

    Article  Google Scholar 

  88. Behmer CJ, AL Demain 1983 Further Studies On Carbon Catabolite Regulation Of $-Lactam Antibiotic Synthesis In Cephalosporium Acremonium. Curr Microbiol 8: 107–114

    Article  Google Scholar 

  89. AP Rees T 1980 Integration Of Pathways Of Synthesis And Degradation Of Hexose Phosphates. In The Biochemistry Of Plants, Vol 3 ( J Preiss, ed), Academic Press, New York pp 1–42

    Google Scholar 

  90. Davies DD 1979 The Central Role Of Phosphoenolpyruvate In Plant Metabolism. Ann Rev Plant Physiol 30: 131–158

    Article  Google Scholar 

  91. Preiss J, T Kosuge 1976 Regulation Of Enzyme Activity In Metabolic Pathways. In Plant Biochemistry ( J Bonner, JE Varner eds), Academic Press, New York pp 277–336

    Google Scholar 

  92. Pryke JA, T AP Rees 1976 Activity Of The Pentose Phosphate Pathway During Lignification. Planta 132: 279–284

    Article  Google Scholar 

  93. Pryke Ja, T AP Rees 1977 The Pentose Phosphate Pathway As A Source Of Nadph For Lignin Biosynthesis. Phytochemistry 16: 557–560

    Article  Google Scholar 

  94. Miflin BH 1973 Amino Acid Biosynthesis And Its Control In Plants. In Biosynthesis And Its Control In Plants ( BV Milborrow, ed) Academic Press, New York, pp 49–68

    Google Scholar 

  95. Miflin BJ 1976 Modification Controls In Time And Space. In Regulation Of Enzyme Synthesis And Activity In Higher Plants ( H. Smith ed), Academic Press, New York pp 23–40

    Google Scholar 

  96. Jessup W, MW Fowler 1976 Interrelationships Between Carbohydrate Metabolism And Nitrogen Assimilation In Cultured Plant Cells. Ii. The Effect Of The Nitrogen Source And Concentration On Nutrient Uptake And Respiratory Activity In Cultured Sycamore Cells. Planta 132: 125–129

    Google Scholar 

  97. Jessup W, M Fowler 1976 Interrelationships Between Carbohydrate Metabolism And Nitrogen Assimilation In Cultured Plant Cells. I. Effects Of Glutamate And Nitrate As Alternative Nitrogen Sources In Cell Growth. Planta 132: 119–123

    Google Scholar 

  98. Seeni S, A Gnanam 1982 Carbon Assimilation In Photoheterotrophic Cells Of Peanut ( Arachis hypogaea L.) grown in still nutrient medium. Plant Physiol 70: 823–826

    Article  Google Scholar 

  99. Dougall DK 1977 Current Problems In The Regulatin Of Nitrogen Metabolism In Plant Cell Cultures. In Plant Cell Culture And Its Bio-Technological Application ( W. Barz, W Reinhard, MH Zenk, eds), Springer-Verlag, Berlin, New York pp 76–94

    Chapter  Google Scholar 

  100. Bradford JA, JS Fletcher 1982 Influence Of Protein On No3 Reduction Nhi* Accumulation, And Amide Synthesis In Suspension Cultures Of Paul’s Scarlet Rose. Plant Physiol 69: 63–66

    Google Scholar 

  101. Jones LH, JN Barrett, PPS Gopal 1973 Growth And Nutrition Of A Suspension Culture Of Pogostemon Cab1In Benth. J Exp Bot 24: 145–158

    Article  MATH  Google Scholar 

  102. Rose D, SM Martin 1974 Parameters For Growth Measurement In Suspension Cultures Of Plants Cells. Can J Bot 52: 903–912

    Article  Google Scholar 

  103. Rose D, SM Martin 1975 Effect Of Ammonium On Growth Of Plant Cells ( Ipomoea sp.) in suspension cultures. Can J Bot 53: 1942–1949

    Google Scholar 

  104. Miflin BJ, PJ Lea 1976 The Pathway Of Nitrogen Assimilation In Plants. Phytochemistry 15: 873–885

    Article  Google Scholar 

  105. Miflin BJ, PJ Lea 1982 Ammonia Assimilation And Amino Acid Metabolism. In Nucleic Acids And Proteins In Plants Encyclopedia Of Plant Physiology New Series, Vol. 14A ( D Boulter, B Parthier eds). Springer-Verlag, Britain pp 5–64

    Chapter  Google Scholar 

  106. Zielke HK, P Filner 1971 Synthesis And Turnover Of Nitrate Reductase Induced By Nitrate In Cultured Tobacco Cells. J Biol Chem 246: 1772–1779

    Google Scholar 

  107. Chroboczek-Kelker H, P Filner 1971 Regulation Of Nitrate And Reductase And Its Relationship To The Regulation Of Nitrate Reductase In Cultured Tobacco Cells. Biochim Biophys Acta 252: 69–82

    Article  Google Scholar 

  108. Filner P 1966 Regulation Of Nitrate Reductase In Cultured Tobacco Cells. Biochim Biophys Acta 118: 299–310

    Article  Google Scholar 

  109. Heimer YM, E Riklis 1979 On The Mechanism Of Development Of Nitrate Reductase Activity In Tobacco Cells. Plant Sci Lett 16: 135–138

    Article  Google Scholar 

  110. Behrend J, RI Mateles 1975 Nitrogen Metabolism In Plant Cell Suspension Cultures. Plant Physiol 56: 584–589

    Article  Google Scholar 

  111. Dougall RK 1977 Current Problems In The Regulation Of Nitrogen Metabolism In Plant Cell Cultures. In Plant Tissue Culture And Its Bio-Technological Application, Springer-Verlag, Berlin, Pp 76–84

    Book  Google Scholar 

  112. Gaines CG, GS Byng, RJ Witaker, RA Jensen 1982 L-Tyrosine Regulation And Biosynthesis Via Arogenate Dehydrogenase In Suspension-Cultured Cells Of Nicotiana Silvestris Speg. Et Comes. Planta 156: 233–240

    Google Scholar 

  113. Jordan DB, JS Fletcher 1979 The Relationship Between No2 Accumulation, Nitrate Reductase And Nitrite Reductase In Suspension Cultures Of Paul’s Scarlet Rose. Plant Sci Lett 17: 95–99

    Google Scholar 

  114. Hahlbrock K 1974 Correlation Between Nitrate Uptake, Growth And Changes In Metabolic Activities Of Cultured Plant Cells. In Tissue Culture And Plant Science (HE Street, ed) Academic Press London pp 363–378

    Google Scholar 

  115. Pahlich E, C Gerlitz 1980 Deviations From Michaelis-Menten Behaviour Of Plant Glutamate Dehydrogenase With Ammonium As Variable Substrate. Phytochemistry 19: 11–13

    Article  Google Scholar 

  116. Ohta S, O Matsui, M Yatazawa 1978 Culture Conditions For Nicotine Production In Tobacco Tissue Culture. Agric Biol Chem 42: 1245–1251

    Article  Google Scholar 

  117. Mehta AT, R Shailaja 1978 Front Plant Tissue Cult, Iaptc Congr 4Th, Calgary Alberta, Poster #1406

    Google Scholar 

  118. Misawa M, K Sakato, H Tanaka, M Hayashi, M Same J Ima 1974 Production Of Physiologically Active Substances By Plant Cell Suspension Cultures. In Tissue Culture And Plant Science ( HE Street, ed), Academic Press, London pp 405–432

    Google Scholar 

  119. Misawa M, H Tanaka, O Chiyo, N Mukai 1975 Production Of A Plasmin Inhibitory Substance By Scopalia Japonica Suspension Cultures. Biotechnol Bioeng 17: 305–334

    Article  Google Scholar 

  120. Rennenberg HL, L Bergman 1979 Einfluss Von Ammonium Und Sulfat Auf Die Glutathion-Produktion In Suspensionkulturen Von Nicotiana Tabacum. Z Pflanzenphysiol 92: 133–142

    Google Scholar 

  121. Sasse F, U Heckenberg, J Berlin 1982 Accumulation Of 3-Carboline Alkaloids And Serotonin By Cell Cultures Of Peganum Harmala L. Plant Physiol. 69: 400–404

    Article  Google Scholar 

  122. Wink M, T Hartman, L Witte 1980 Biotransformation Of Cadaverine And Potential Biogenetic Intermediates Of Lupanine Biosynthesis By Plant Cell Suspension Cultures. Planta Med 40: 31–39

    Article  Google Scholar 

  123. Steck W, OL Gamborg, BK Bailey 1973 Increased Yields Of Alkaloids Through Precursor Biotransformation In Cell Suspension Ruga Graveolens. Lloydia 36: 93–95

    Google Scholar 

  124. Tabata M, H Yamamoto, N Hiraoka, M Konoshima 1972 Organization And Alkaloid Production In Tissue Cultures Of Scopolia Parviflora. Phytochemistry 11: 949–955

    Article  Google Scholar 

  125. Hiraoka N, M Tabata, M Konoshima 1973 Formation Of Acetyltropine In Datura Callus Cultures. Phytochemistry 12: 795–799

    Article  Google Scholar 

  126. Razzaque A, BE Ellis 1977 Rosmarinic Acid Production In Coleus Cell Cultures. Planta 137: 287–291

    Article  Google Scholar 

  127. Sairam TV, P Khanna 1971 Effect Of Tyrosine Production Of Alkaloids In Datura Tatula Tissue Cultures. Lloydia 34: 170–174

    Google Scholar 

  128. Kamimura S, M Akutsu, M Nishikawa 1976 Formation Of Thebaine In Suspension Cultures Papaver Bracteatum. Agric Biol Chem 40: 913–919

    Article  Google Scholar 

  129. Kuang-Chich C, L Cheng 1981 Callus Cultures Of The Three Well-Known Chinese Herbs And Their Medicinal Contents. In Plant Tissue Culture. ( H Hu ed) Pitman Publishing Ltd London pp 469–479

    Google Scholar 

  130. See Reference 124.

    Google Scholar 

  131. Krueger RJ, DP Carew 1978 Catharanthus Roseus Tissue Culture: The Effects Of Precursors On Growth And Alkaloid Production. Lloydia 41: 327–331

    Google Scholar 

  132. Deus B 1978 Zellkulturen Von Catharanthus Roseus. In Production Of Natural Compounds By Cell Culture Methods ( AW Alfermann, E Reinhard, eds). Gesellschaft für Strahlen-und Umweltforschung mbH, Munich, pp 118–123

    Google Scholar 

  133. Berlin J, L Witte 1982 Metabolism Of Phenylalanine And Cinnamic Acid In Tobacco Cell Lines With High And Low Yields Of Cinnamoyl Putrescines. J Nat Prod 45: 88–93

    Article  Google Scholar 

  134. Veliky IA 1972 Synthesis Of Carboline Alkaloids By Plant Cell Cultures. Phytochemistry 11: 1405–1406

    Article  Google Scholar 

  135. Veliky IA, KM Barber 1975 Biotransformation Of Tryptophan By Phaseolus Vulgaris Suspension Culture. Lloydia 38: 125–130

    Google Scholar 

  136. Khanna P, R Khanna, M Sharma 1978 Production Of Free Ascorbic Acid And Effect Of Exogenous Ascorbic Acid And Tyrosine On Production Of Major Opium Alkaloids From In Vitro Tissue Cultures Of Papaver Somniferum Linn. Indian J Exp Biol 16: 110–112

    Google Scholar 

  137. Hus A-F 1981 Effect Of Protein Synthesis Inhibitors On Cell Cultures Of Papaver Somniferum. J Nat Prod 44: 408–414

    Article  Google Scholar 

  138. Nettleship L, S Slaytor 1974 Limitations Of Feeding Experiments In Studying Alkaloid Biosynthesis In Peganum Harmala Callus Cultures. Phytochemistry 13: 735–742

    Article  Google Scholar 

  139. Kaul B, SJ Stohs, EJ Staba 1969 Dioscorea Tissue Cultures. Iii. Influence Of Various Factors On Diosgenin Production By Dioscorea Deltoidea Callus And Suspension Cultures. Lloydia 32: 347–359

    Google Scholar 

  140. Margna U 1977 Control At The Level Of Substrate Supply-An Alternative In The Regulation Of Phenylpropanoid Accumulation In Plant Cells. Phytochemistry 16: 419–426

    Article  Google Scholar 

  141. Widholm JM 1972 Tryptophan Biosynthesis In Nicotiana Tabacum And Daucus Carota Cell Cultures: Site Of Action Of Inhibitory Tryptophan Analogs. Biochim Biophys Acta 261: 44–51

    Article  Google Scholar 

  142. Belser WL, Jb Murphy, Dp Delmer, Se Mills End Product Control Of Tryptophan Biosynthesis In Extracts And Intact Cells Of Higher Plant Nicotiana Tabacum Var. Wisconsin 38. Biochim Biophys Acta 237: 1–10

    Google Scholar 

  143. Floss HG, JE Robbers, PF Heinstein 1974 Regulatory Control Mechanisms In Alkaloid Biosynthesis. Recent Adv Phytochem 8: 141–178

    Google Scholar 

  144. Bucholz D, B Reupke, H Bickel, G Schultz 1979 Reconstitution Of Amino Acid Synthesis By Combining Spinach Chloroplasts With Other Leaf Organelles. Phytochemistry 18: 1109–1111

    Article  Google Scholar 

  145. Bickel H, L Palme, G Schultz 1978 Incorporation Of Shikimate And Other Precursors Into Aromatic Amino Acids And Prenylquinones Of Isolated Spinach Chloroplasts. Phytochemistry 17: 119–124

    Article  Google Scholar 

  146. Aharonowitz Y 1980 Nitrogen Metabolite Regulation Of Antibiotic Biosynthesis. Ann Rev Microbiol 34: 209–233

    Article  Google Scholar 

  147. Swutzer RK 1977 The Inactivation Of Microbial Enzymes In Vivo. Ann Rev Microbiol 31: 135–157

    Article  Google Scholar 

  148. Lorimer GH, Hs Gewitz, W Voelker, Lp Solomonson, B Vennesland 1974 The Presence Of Bound Cyanide In The Naturally Inactivated Form Of Nitrate Reductase Of Chlorella Vulgaris. J Biol Chem 249: 6074–6079

    Google Scholar 

  149. Edwards GE, Sc Huber 1981 The Ci+ Pathway. In The Biochemistry Of Plants, A Comprehensive Treatise, Vol 8 ( MD Hatch, NK boardman, eds), Academic Press, New York pp 237–281

    Google Scholar 

  150. Wiskich JT 1980 Control Of The Krebs Cycle. In The Biochemistry Of Plants, A Comprehensive Treatise, Vol 2 ( DD Davies, ed) Academic Press, New York pp 243–278

    Google Scholar 

  151. Turner JF, DH Turner 1980 The Regulation Of Glycolysis And The Pentose Phosphate Pathway. In The Biochemistry Of Plants, A Comprehensive Treatise, Vol 2 ( DD Davies, ed) Academic Press, New York pp 279–316

    Google Scholar 

  152. Ross CE 1981 Biosynthesis Of Nucleotides. In The Biochemistry Of Plants, A Comprehensive Treatise, Vol 6 ( A Marcus, ed) Academic Press, New York pp 169–205

    Google Scholar 

  153. Mudd JB 1980 Phospholipid Biosynthesis. In The Biochemistry Of Plants, A Comprehensive Treatise, Vol 4 ( PK Stumpf, ed) Academic Press, New York pp 249–282

    Google Scholar 

  154. Knobloch K-H, J Berlin 1981 Phosphate Mediated Regulation Of Cinnamoyl Putrescine Biosynthesis In Cell Suspension Cultures Of Nicotiana Tabacum. Planta Med 42: 167–172

    Article  Google Scholar 

  155. Hinz H, MH Zenk 1981 Production Of Protoberine Alkaloids By Cell Suspension Cultures Of Berberis Species. Naturwissenschaften 68: 620–621

    Article  ADS  Google Scholar 

  156. Dobberstein RH, EJ Staba 1969 Ipomoea, Rivea And Argyreia Tissue Cultures: Influence Of Various Chemical Factors On Indole Alkaloid Production And Growth. Lloydia 32: 141–152

    Google Scholar 

  157. Kurpinski VM, JE Robbers, HG Floss 1976 Physiological Study Of Ergot: Induction Of Alkaloid Synthesis By Tryptophan At The Enzymatic Level. J Bacteriol 125: 158–165

    Google Scholar 

  158. Erge D, M Maier, D Groeger 1973 Untersuchungen Über Enzymatische Umwandlung Von Chanoclavin-I. Biochem Physiol Pflanzen 164: 234–247

    Google Scholar 

  159. Weinberg ED 1974 Secondary Metabolism: Control By Temperature And Inorganic Phosphate. Dev Ind Microbiol 15: 70–81

    Google Scholar 

  160. Tal B, JS Rokem, I Goldberg 1983 Factors Affecting Growth And Product Formation In Plant Cells Grown In Continuous Culture. Plant Cell Reports 2: 219–222

    Article  Google Scholar 

  161. Benjamin BD, MR Heble, MS Chadha 1978 Alkaloid Synthesis In Tissue Cultures And Regenerated Plants By Tylophora Indica Merr. (Asclepidaceae). Z Pflanzenphysio1 92: 77–84

    Google Scholar 

  162. Beevers L 1982 Post-Transitional Modifications. In Nucleic Acids And Proteins In Plants. Encyclopaedia Of Plant Physiology New Series Vol 14 A, (D Boulter, B Parthier, eds). Springer-Verlag, Berlin, pp 136–168

    Google Scholar 

  163. Devlin DM 1975 Plant Physiology. D Van Nostrand Co. New York 600 Pp

    Google Scholar 

  164. Rains DW 1976 Mineral Metabolism. In Plant Biochemistry ( J Bonner, JE Varner, eds). Academic Press, New York, pp 561–597

    Google Scholar 

  165. Webster GC 1953 Enzymatic Synthesis Of Gamma-Glutamyl-Cysteine In Higher Plants. Plant Physiol 28: 728–730

    Article  Google Scholar 

  166. Croteau R, F Karp 1976 Enzymatic Synthesis Of Camphor From Neryl Pyrophosphate By A Soluble Preparation From Sage ( Salvia officinalis ). Biochem Biophys Res Commun 72: 440–447

    Google Scholar 

  167. Frost RG, CA West 1977 Properties Of Kaurene Synthetase From Marah Macrocarpa. Plant Physiol 59: 22–29

    Article  Google Scholar 

  168. Rappaport L, D Adams 1978 Gibberellins: A Synthesis, Compartmentation And Physiological Process. Phil Trans R Soc London B 284: 521–539

    Google Scholar 

  169. Schiff JA, RC Hodson 1973 The Metabolism Of Sulfate. Ann Rev Plant Physiol 24: 381–414

    Article  Google Scholar 

  170. Anderson JW 1980 Assimilation Of Inorganic Sulphate In Cysteine. In The Biochemistry Of Plants, Vol. 5 ( BJ Miflin, ed) Academic Press, New York pp 203–223

    Google Scholar 

  171. Giovanelli J, SH Mudd, AH Datko 1980 Sulfur Amino Acids In Plants. In The Biochemistry Of Plants, Vol. 5 ( BJ Miflin, ed) Academic Press, New York, pp 453–505

    Google Scholar 

  172. Schwenn JD, U Schriek, H Kiltz 1983 Dissimilation Of Methionine In Cell Suspension Cultures From Catharanthus Roseus. Planta 158: 540–549

    Article  Google Scholar 

  173. Cantoni GL 1977 S-Adenosylmethionine: Present Status And Future Perspectives. In The Biochemistry Of Adenosymethionine, ( F. Salvatore, E Borek, V Zappia, HG Williams-Ashman, F Schlenk, eds), Columbia Univ Press, New York pp 557–577

    Google Scholar 

  174. Castle M, G Blondin, WR Nes 1963 Evidence For The Origin Of The Ethyl Group Of B-Sitosterol. J Am Chem Soc 85: 3306–3308

    Article  Google Scholar 

  175. Chen Y, E Zahavi, P Barak, N Umiel 1980 Effects Of Salinity Stresses On Tobacco I. The Growth Of Nicotiana Tabacum Callus Cultures Under Seawater, Nacl, And Mannitol Stresses. Z Pflanzenphysiol 98: 141–153

    Google Scholar 

  176. Lipetz J 1962 Calcium And The Control Of Lignification In Tissue Cultures. Amer J Bot 49: 460–464

    Article  Google Scholar 

  177. Klapheck S, W Grosse, L Bergmann 1982 Effect Of Sulfur Deficiency On Protein Synthesis And Amino Acid Accumulation In Cell Suspension Cultures Of Nicotiana Tabacum. Z Pflanzenphysiol 108: 235–245

    Google Scholar 

  178. Dix PH, RS Pearce 1981 Proline Accumulation In Nacl Resistant And Sensitive Cell Lines Of Nicotiana Sylvestris. Z Pflanzenphysiol 102: 243–248

    Google Scholar 

  179. Heyser JW, MW Nabors 1981 Osmotic Adjustment Of Cultured Tobacco Cells (Nicotiana tabacum var. Samsum) grown on sodium chloride. Plant Physiol 67: 720–727

    Google Scholar 

  180. Garcia FG, JW Einset 1983 Ethylene And Ethane Production In 2,4-D Treated And Salt Treated Tobacco Tissue Cultures. Ann Bot 51: 287–295

    Google Scholar 

  181. Mackenzie IA, HE Street 1970 Studies Of The Growth In Culture Of Plant Cells. Viii. Production Of Ethylene By Suspension Cultures Of Acer Pseudoplatanus L. J Exp Bot 21: 824–834

    Google Scholar 

  182. Shah Rr, Kv Subbaiah, AR Mehta 1976 Hormonal Effect On Polyphenol Accumulation In Cassia Tissues Cultured In Vitro. Can J Bot 54: 1240–1245

    Article  Google Scholar 

  183. Mckenzie E, L Nettleship, M Slaytor 1975 New Natural Products From Peganum Harmala. Phytochemistry 14: 273–275

    Article  Google Scholar 

  184. Lam TH, HE Street 1977 The Effects Of Selected Aryloxyalkanecarboxylic Acids On The Growth And Levels Of Soluble Phenols In Cultured Cells Of Rosa Damascena. Z Pflanzenphysiol 84: 121–128

    Google Scholar 

  185. See Reference 180

    Google Scholar 

  186. Kurkdjian A, Y Mathieu, J Guern 1982 Evidence For An Action Of 2,4-Dichlorophenoxyacetic Acid On The Vacuolar Ph Of Acer Pseudoplatanus Cells In Suspension Culture. Plant Sci Lett 27: 77–86

    Article  Google Scholar 

  187. Tabata M, N Hiraoka, M Ikenoue, Y Sano, M Konoshima 1975 The Production Of Anthaquinones In Callus Cultures Of Cassia Tora. Lloydia 38: 131–134

    Google Scholar 

  188. Mulder-Krieger T, R Verpoorte, YP De Graaf, M Vander Kreek, A Baerheim-Svendsen 1982 The Effects Of Plant Growth Regulators And Culture Conditions On The Growth And The Alkaloid Content Of Cultures Of Cinchona Pubsecens. Planta Med 46: 15–18

    Article  Google Scholar 

  189. Ikuta A, K Syono, T Furuya 1975 Alkaloids In Plants Regenerated From Coptis Callus Cultures. Phytochemistry 14: 1209–1210

    Article  Google Scholar 

  190. Ozeki Y, A Komamine 1981 Induction Of Anthocyanin Synthesis In Relation To Embryogenesis In A Carrot Suspension Culture: Correlation Of Metabolic Differentiation With Morphological Differentiation. Physiol Plant 53: 570–577

    Google Scholar 

  191. Romeike A 1975 Versuche Zur Veresterung Von Tropin Und Tropasaure An Pflanzenzellkulturen. Biochem Physiol Pflanzen 168: 87–92

    Google Scholar 

  192. Hiraoka N, M Tabata 1983 Acetylation Of Tropane Derivatives By Datura Innoxia Cell Cultures. Phytochemistry 22: 409–412

    Article  Google Scholar 

  193. Harborne JB, J Arditti, E Ball 1970 (Abstract) The anthocyanins of callus culture from the stem of Dimorphotheca auriculata ( Cape marigold, Compositae). Am J Bot 57: 763

    Google Scholar 

  194. Marshall JG, EJ Staba 1976 Hormonal Effects Of Diosgenin Biosynthesis And Growth In Dioscorea Deltoidea Tissue Cultures. Phytochemistry 15: 53–55

    Article  Google Scholar 

  195. Heinstein P, H El-Shagi 1981 Formation Of Gossypol By Gossypium Hirsutum L. Cell Suspension Cultures. J Nat Prod 44: 1–6

    Google Scholar 

  196. Fukui H, M Tsukada, H Mizukami, M Tabata 1983 Formation Of Stereoisomeric Mixtures Of Naphthoquinones Derivatives In Echium Lycopsis Callus Cultures. Phytochemistry 22: 453–456

    Article  Google Scholar 

  197. Strickland Rg, N Sunderland 1972 Production Of Anthocynins, Flavonols, And Chlorogenic Acids By Cultured Callus Tissues Of Haplopappus Gracilis. Ann Bot 36: 443–457

    Google Scholar 

  198. Constabel F, JP Shyluk, OL Gamborg 1971 The Effect Of Hormones On Anthocyanin Accumulation In Cell Cultures Of Haplopappus Gracilis. Planta 96: 306–316

    Article  Google Scholar 

  199. Ibrahim RK, ML Thakur, B Permanand 1971 Formation Of Anthocyanins In Callus Tissue Cultures. Lloydia 34: 175–182

    Google Scholar 

  200. Furuya T, H Kojima, K Syono 1971 Regulation Of Nicotine Biosynthesis By Auxins In Tobacco Callus Tissues. Phytochemistry 10: 1529–1532

    Article  Google Scholar 

  201. Shiio I, S Ohta 1973 Nicotine Production By Tobacco Callus Tissues And Effect Of Plant Growth Regulators. Agric Biol Chem 37: 1857–1964,201. Okazaki M, F Hino, K Kominami, Y Miura 1982 Effects Of Plant Hormones On Formation Of Scopoletin And Scopolin In Tobacco Tissue Cultures. Agric Biol Chem 46: 609–614

    Google Scholar 

  202. Zito SW, EJ Staba 1982 Thebaine From Root Cultures Papaver Bracteatum. Planta Med 45: 53–54

    Article  Google Scholar 

  203. Hodges CC, H Rapoport 1982 Morphinan Alkaloids In Callus Cultures Of Papaver Somniferum. J Nat Prod 45: 482–485

    Article  Google Scholar 

  204. Smith SL, GW Slywka, J Krueger 1981 Anthocyanins Of Strobilanthes Dyeriana And Their Production In Callus Culture. J Nat Prod 44: 609–610

    Article  Google Scholar 

  205. Van Den Berg AJJ, RP Labadie 1981 The Production Of Acetate Derived Hydroxyanthraquinones,-Dianthrones,-Naphthalenes And L-Benzenes In Tissue Cultures From Rumex Alpinus. Planta Med 41: 169–173

    Article  Google Scholar 

  206. Phillips R, GG Henshaw 1977 The Regulation Of Synthesis Of Phenolics In Stationary Phase Cell Cultures Of Acer Pseudoplatanus L. J Exp Bot 28: 785–794

    Article  Google Scholar 

  207. King PJ 1976 Studies On The Growth Culture Of Plant Cells. Xx. Utilization Of 2,4-Dichlorophen-Oxyacetic Acid By Steady-State Cell Cultures Of Acer Pseudoplatanus. J Exp Bot 27: 1053–1072

    Article  Google Scholar 

  208. Al-Abta S, IJ Galpin, HA Colin 1979 Flavour Compounds In Tissue Cultures Of Celery. Plant Sci Lett 16: 129–134

    Article  Google Scholar 

  209. Kaul B, EJ Staba 1968 Dioscorea Tissue Cultures. I. Biosynthesis And Isolation Of Diosgenin From Dioscorea Deltoidea Callus Suspension Cells. Lloydia 31: 171–179

    Google Scholar 

  210. Nishi A, I Tsuritani 1983 Effect Of Auxin On The Metabolism Of Mevalonic Acid In Suspension-Cultured Carrot Cells. Phytochemistry 22: 399–401

    Article  Google Scholar 

  211. Shimizu K, T Kikuchi, N Sugano, A Nishi 1979 Carotenoid And Steroid Synthesis By Carrot Cells In Suspension. Physiol Plant 46: 127–132

    Article  Google Scholar 

  212. Barz W, H Herzbeck, W Husemann, G Schneiders, HK Mangold 1980 Alkaloids And Lipids Of Heterotrophic, Photomixotrophic And Photoautotrophic Cell Suspension Cultures Of Peganum Harmala. Planta Med 40: 137–148

    Google Scholar 

  213. Rucker W, K Jentzsch, W Wichtl 1981 Organdifferenzierung Und Glykosidbildung Bei In Vitro Kultivierten Blattexplantaten Von Digitalis Purpurea L.; Einfluss Verschiedener Wuchsstoffe, Nährlösungen Und Lichtverhältnisse. Z Pflanzenphysiol 102: 207–220

    Google Scholar 

  214. Biesboer DD, PG Mahlberg 1979 The Effect Of Medium Modification On Selected Precursors On Sterol Production By Short-Term Callus Cultures Of Euphorbia Tirucalli. J Nat Prod 42: 648–657

    Article  Google Scholar 

  215. Tabata M, H Mizukami, N Hiraoka, M Konoshima 1974 Pigment Formation In Callus Cultures Of Lithospermum Erythrorhizon. Phytochemistry 13: 927–932

    Article  Google Scholar 

  216. Saleh MM 1982 (Abstract). Effect of environment on the growth and glycosides of callus tissue. of Digitalis lanata. Planta Med 45: 135

    Google Scholar 

  217. Stearns EM, WT Morton 1975 Effects Of Growth Regulators On Fatty Acids Of Soybean Suspension Cultures. Phytochemistry 14: 619–622

    Article  Google Scholar 

  218. Misawa M 1977 Production Of Natural Substances By Plant Cell Cultures Described In Japanese Patents. In Plant Tissue Culture And Its Bio-Technological Application ( W. Barz, E. Reinhard, MH Zenk eds.). Springer-Verlag, Berlin, pp 17–26

    Chapter  Google Scholar 

  219. Miller CO 1969 Control Of Deoxyisoflavone Synthesis In Soybean Tissue. Planta 87: 26–35

    Article  Google Scholar 

  220. Muller W-U, E Leistner 1978 Aglycones And Glucosides Of Oxygenated Naphthalenes And Glycosyl Transferase From Juglans. Phytochemistry 17: 1739–1742

    Article  Google Scholar 

  221. Ibrahim RK, D Edgar 1976 Phenolic Synthesis In Perilla Cell Suspension Cultures. Phytochemistry 15: 129–131

    Article  Google Scholar 

  222. See Reference 205

    Google Scholar 

  223. Schmitz M, U Scitz 1972 Hemmung Der Anthocyansynthese Durch Gibberellinsäure A3 Bei Kallusculturen Von Daucus Carota. Z Pflanzenphysiol 68: 259–265

    Google Scholar 

  224. Braun G, Ü Scitz 1975 Verlauf Der Akkumulation Von Kaffe-, Ferula-Und Chlorogensäure In Beziehung Zur Cyanodinakkumulation Bei 2 Zellinien Von Daucus Carota. Biochem Physiol Pflanzen 168: 93–100

    Google Scholar 

  225. Lui Jhc, EJ Staba 1981 Effects Of Age And Growth Regulators On Serially Propogated Digitalis Lanata Leaf And Root Cultures. Plant Med 41: 90–95

    Article  Google Scholar 

  226. Yamada Y, T Kuboi 1976 Significance Of Caffeic Acid-O-Methyltransferase In Lignification Of Cultured Tobacco Cells. Phytochemistry 15: 395–396

    Article  Google Scholar 

  227. Kuboi T, Y Yamada 1976 Caffeic Acid-O-Methyltransferase In A Suspension Cell Aggregates Of Tobacco. Phytochemistry 15: 397–400

    Article  Google Scholar 

  228. Cottle W, PE Kolattukudy 1982 Abscissic Acid Stimulation Of Suberization. Inducation Of Enzymes And Deposition Of Polymeric Components And Associated Waxes In Tissue Cultures Of Potato Tuber. Plant Physiol 70: 775–780

    Google Scholar 

  229. Soliday CL, BB Dean, PE Kolattukudy 1978 Suberization: Inhibition By Washing And Stimulation Of Abscissic Acid In Potato Disks And Tissue Culture. Plant Physiol 61: 170–174

    Article  Google Scholar 

  230. Stohs SJ, CS Tamg, H Rosenberg 1977 Influence Of Cyclic Amp On Growth And Steroid Formation In Corchorus Olitorius L. Suspension Cultures. Lloydia 40: 370–373

    Google Scholar 

  231. Mathew T, IC Dave, BK Gaur 1978 Effect Of Gibberellic Acid, Indole-3-Acetic Acid And L-Ascorbic Acid On The Regulation Of Rna Metabolism In De-Etoliated Barley Shoot. Z Pflanzenphysiol 90: 391–396

    Google Scholar 

  232. Nettleship L, M Slaytor 1971 Ruine: A Glycosidic ß-Carboline From Peganum Harmala. Phytochemistry 10: 231–234

    Google Scholar 

  233. Allen JRF, BR Holmstedt 1980 The Simple ß-Carboline Alkaloids. Phytochemistry 19: 1573–1582

    Article  Google Scholar 

  234. Ikuta A, H Itokawa 1982 Berberine And Other Protoberine Alkaloids In Callus Tissue Of Thalictrum Minus. Phytochemistry 21: 1419–1421

    Article  Google Scholar 

  235. Gregor HD 1974 Einfluss Von Gibberellinsäure A3 Auf Die Pal-Aktivität Und Die Synthese Von Phenylpropanderivaten In Zellkulturen Von Haplopappus Gracilis. Protoplasma 80: 273–277

    Article  Google Scholar 

  236. Sugano N, K Hayashi 1967 Dynamic Interrelation Of Cellular Ingredients Relevant To The Biosynthesis Of Anthocyanin During Tissue Culture Of Carrot Aggregen. Bot Mag (Tokyo) 80: 440–449

    Google Scholar 

  237. Davies ME 1972 Effects Of Auxin On Polyphenol Accumulation And The Development Of Phenylalanine Ammonia Lyase Activity In Dark Suspension Cultures Of Paul’s Scarlet Rose. Planta 104: 66–77

    Article  Google Scholar 

  238. Waller GR, S Mangiafico, RC Foster, RH Lawrence 1981 Sterols Of Delphinium Ajacis Production And Metabolic Relationships In Whole Plants And Callus Tissue. Planta Med 42: 344–355

    Article  Google Scholar 

  239. Rucker W, K Jentzsch, M Wichtl 1981 Organdifferenzierung Und Glykosidbildung Bei In Vitro Kultivierten Blattexplantaten Von Digitalis Purpurea L.; Enfluss Verschiedener Wuchsstoffe, Nährlösungen Und Lichtverhältnisse. Z Pflanzenphysiol 102: 207–220

    Google Scholar 

  240. Balague C, A Latche, J Fallot, J-C Pech 1983 Some Physiological Changes Occurring During The Senescence Of Auxin-Deprived Pear Cells In Culture. Plant Physiol 69: 1339–1343

    Article  Google Scholar 

  241. Entsch B, CW Parker, DS Letham 1983 An Enzyme From Lupin Seeds Forming Alanine Derivatives Of Cytokinins. Phytochemistry 22: 373–381

    Article  Google Scholar 

  242. Scibert M, PG Kadkade 1980 Environmental Factors: A. Light. In Plant Tissue Culture As A Source Of Biochemicals ( E. J. Staba ed.). CRC Press, Florida, pp 123–141

    Google Scholar 

  243. Senger H 1982 The Effect Of Blue Light On Plants And Microorganisms. Phytochemistry 35: 911–920

    Google Scholar 

  244. Grisebach H, K Hahlbrock 1974 Enzymology And Regulation Of Flavonoid And Lignin Biosynthesis In Plants And Cell Suspension Cultures. Recent Adv Phytochem 8: 21–52

    Google Scholar 

  245. Lackman I 1971 Wirkungsspektren Der Anthocyansynthese In Gewebekulturen Und Keimlingen Von Haplopappus Gracilis. Planta 98: 258–269

    Article  Google Scholar 

  246. Strickland RG, N Sunderland 1972 Photocontrol Of Growth, And Of Anthocyanin And Chlorogenic Acid Production In Cultured Callus Tissues Of Haplopappus Gracilis. Ann Bot 36: 671–685

    Google Scholar 

  247. Gregor HD, J Reinert Induktion Der Phenylalanin Ammoniumlyase In Gewebekulturen Von Haplopappus Gracilis. Protoplasma 74: 307–319

    Google Scholar 

  248. Ibrahim RK, ML Thakur, B Permanand 1971 Formation Of Anthocyanins In Callus Tissue Cultures. Lloydia 34: 175–182

    Google Scholar 

  249. Takeda R, K Katoh 1981 Growth And Sesquiterpenoid Production By Calypogeia Granulata Inoue Cells In Suspension Culture. Planta 151: 525–530

    Article  Google Scholar 

  250. Wellman E 1971 Phytochrome-Mediated Flavone Glycoside Synthesis In Cell Suspension Cultures Of Petroselinum Hortense After Preirradation With Ultraviolet Light. Planta 101: 283–286

    Article  Google Scholar 

  251. Duell-Pfaff N, E Wellmann 1982 Involvement Of Phytochrome And A Blue Light Photoreceptor In Uv-B Induced Flavonoid Synthesis In Parsley ( Petroselinum hortense Hoffm) cell suspension cultures. Planta 156: 213–217

    Google Scholar 

  252. Hahlbrock K, J Ebel, R Ortman, A Sutter, E Wellman, H Grisebach 1971 Regulation Of Enzyme Activities Related To The Biosynthesis Of Flavone Glycosides In Cell Suspension Cultures Of Parsley ( Petroselinum hortense ). Biochem Biophys Acta 244: 7–15

    Google Scholar 

  253. Hahlbrock K, K-H Knobloch, F Kreuzaler, JRM Potts, E Wellmann 1976 Coordinated Induction And Subsequent Activity Changes Of Two Groups Of Metabolically Interrelated Enzymes. Light-Induced Synthesis Of Flavonoid Glycosides In Cell Suspension Cultures Of Petroselinum Hortense. Eur J Biochem 61: 199–216

    Article  Google Scholar 

  254. Ebel J, K Hahlbrock 1977 Enzymes Of Flavone And Flavonol-Glycoside Biosynthesis. Coordinated And Selective Induction In Cell-Suspension Cultures Of Petroselinum Hortense. Eur J Biochem 75: 201–209

    Google Scholar 

  255. Murphy TM, GB Matson, SL Morrison 1983 Ultraviolet-Stimulated Khco3 Efflux From Rose Cells. Regulation Of Cytoplasmic Ph. Plant Physiol 73: 20–24

    Google Scholar 

  256. Corduan G, E Reinhard 1972 Synthesis Of Volatile Oils In Tissue Cultures Of Ruta Graveolens. Phytochemistry 11: 917–922

    Article  Google Scholar 

  257. Jente R 1971 Polyacetylenverbindungen In Gewebekulturen Von Centaurea Ruthenica Lam. Tetrahedron 27: 4077–4083

    Article  Google Scholar 

  258. Ichihara K, M Noda 1977 Distribution And Metabolism Of Polyacetylenes In Safflower. Biochim Biophys Acta 487: 249–260

    Article  Google Scholar 

  259. Radin DN, HM Behl, P Proksch, E Rodriguez 1982 Rubber And Other Hydrocarbons Produced In Tissue Cultures Of Guayule ( Parthenium argentatum ). Plant Sci Lett 26: 301–310

    Google Scholar 

  260. Roller U 1978 Selection Of Plants And Plant Tissue Cultures Of Catharanthus Roseus With High Content Of Serpentine And Ajmalicine. In Production Of Natural Compound By Cell Culture Methods ( AW Alfermann, E Reinhard, eds.). Gesellschaft fur Strahlen-und Umweltforschung mbH. Munich, pp 95–104

    Google Scholar 

  261. Ohta S, M Yatazawa 1978 Effect Of Light On Nicotine Production In Tobacco Tissue Culture. Agric Biol Chem 42: 873–877

    Article  Google Scholar 

  262. Hahlbrock K 1972 Isolation Of Apigenin From Illuminated Cell Suspension Cultures Of Soybean, Glycine Max. Phytochemistry 11: 165–167

    Article  Google Scholar 

  263. Brunet G, RK Ibrahim 1973 Tissue Culture Of Citrus Peel And Its Potential For Flavonoid Synthesis. Z P Flanz Enphy S Io1 69: 152–162

    Google Scholar 

  264. Gregor HD, J Reinert 1972 Induktion Der Phenylalanine Ammonia-Lyase In Gewebekulturen Von Haplopappus Gracilis. Protoplasma 74: 307–319

    Article  Google Scholar 

  265. Fritsch H, K Hahlbrock, H Grisebach 1971 Biosynthese Von Cyanidin In Zellsuspension-Kulturen Von Haplopappus Gracilis. Z Naturforsch 266: 581–585

    Google Scholar 

  266. Jones RW, RW Sheard 1977 Effects Of Blue And Red Light On Nitrate Reductase Level In Leaves Of Maize And Pea Seedlings. Plant Sci Lett 8: 305–311

    Article  Google Scholar 

  267. Aparicio PJ, JM Roldan, F Calero 1976 Blue Light Photoreaction Of Nitrate Reductase From Green Algae And Higher Plants. Biochem Biophys Res Comm 70: 1071–1077

    Article  Google Scholar 

  268. Roldan JM, F Calero, PJ Aparicio 1978 Photoreactivation Of Spinach Nitrate Reductase: Role Of Flavins. Z Pflanzenphysiol 90: 467–474

    Google Scholar 

  269. See Reference 168.

    Google Scholar 

  270. Madyastha KM, JE Ridgway, JG Dwyer, CJ Cocia 1977 Subcellular Localization Of A Cytochrome P450-Dependent Monooxygenase In Vescicles Of The Higher Plant Catharanthus Roseus. J Cell Biol 72: 302–313

    Article  Google Scholar 

  271. Grunwald C 1978 Function Of Sterols. Phil Trans R Soc Lond B 284: 541–558

    Article  ADS  Google Scholar 

  272. Wellburn AR 1982 Bioenergetic And Ultrastructural Changes Associated With Chloroplast Development. Int Rev Cytol 80: 133–191

    Article  Google Scholar 

  273. Harding RW, W Shropshire 1980 Photocontrol Of Carotenoid Biosynthesis. Ann Rev Plant Physiol 31: 217–238

    Article  Google Scholar 

  274. Thomas RL, JJ Jen 1975 Phytochrome-Mediated Carotenoids, Biosynthesis In Ripening Tomatoes. Plant Physiol 56: 452–453

    Google Scholar 

  275. Schopfer P 1977 Phytochrome Control Of Enzymes. Ann Rev Plant Physiol 28: 233–252

    Article  Google Scholar 

  276. Anderson LE, TCL Ng, KEY Park 1974 Interaction Of Pea Leaf Chloroplastic And Cytoplasmic Glucose-6-Phosphate Dehydrogenase By Light And Dithiothreitol. Plant Physiol 53: 835–839

    Article  Google Scholar 

  277. Reed AJ, DT Canvin, JH Sherrard, RH Hageman 1983 Assimilation Of [15N] Nitrate And [15N] Nitrate In Leaves Of Five Plant Species Under Light And Dark Conditions. Plant Physiol 71: 291–294

    Article  Google Scholar 

  278. Buchanan BB 1980 Role Of Light In The Regulation Of Chloroplast Enzymes. Ann Rev Physiol 31: 341–374

    Article  Google Scholar 

  279. Smith H, EE Billet, AB Giles 1977 The Photocontrol Of Gene Expression In Higher Plants. In Regulation Of Enzyme Synthesis And Activity In Higher Plants ( H. Smith ed.). Academic Press, New York, pp 93–127

    Google Scholar 

  280. Harel E 1978 Chlorophyll Biosynthesis And Its Control. In Progress In Phytochemistry, Vol. 5 ( L Reinhold, JB Harborne, T Swain eds.). Pergamon Press Toronto, pp 127–180

    Google Scholar 

  281. Hahlbrock K, H Grisebach 1979 Enzymic Controls In The Biosynthesis Of Lignin And Flavonoids. Ann Rev Plant Physiol 30: 105–130

    Article  Google Scholar 

  282. Forrest GE 1969 Studies Of Polyphenol Metabolism Of Tissue Cultures Derived From The Tea Plant (Camellia sinensis L.). Biochem J 113: 765–772

    Google Scholar 

  283. Radwan SS, HK Mangold, H Husemann, W Barz 1979 Lipids In Plant Tissue Cultures. Vii. Heterotrophic And Mixotrophic Cell Cultures Of Chenopodium Rubrum. Chem Phys Lipids 24: 79–84

    Google Scholar 

  284. Thomas DR, AK Stobart 1970 Lipids Of Tissue Cultures Of Kalanchoe Crenata. J Exp Bot 21: 274–285

    Article  Google Scholar 

  285. Radwan SS, S Grosse-Oetringhaus, Hk Mangold 1978 Lipids In Plant Tissue Cultures. Vi. Effect Of Temperature On The Lipids Of Brassica Napus And Tropaeolum Majus Cultures. Chem Phys Lipids 22: 177–184

    Google Scholar 

  286. Mangold HK 1977 The Common And Unusual Lipids Of Plant Cell Cultures. In Plant Tissue Culture And Its Biotechnological Application ( W. Barz, E. Reinhard, MH Zenk eds.). Springer-Verlag, Berlin, pp 55–65

    Chapter  Google Scholar 

  287. Gower M, A Sansonetti, P Mazliak 1983 Lipid Composition Of Tobacco Cells Cultivated At Various Temperatures. Phytochemistry 22: 855–859

    Article  Google Scholar 

  288. Courtois D, J Guern 1980 Temperature Response Of Catharanthus Roseus Cells Cultivated In Liquid Medium. Plant Sci Lett 17: 473–482

    Article  Google Scholar 

  289. Baqar MR, TH Lee 1978 The Interaction Of Cpta And High Temperature On Carotenoid Synthesis In Tomato Fruit. Z Pflanzenphysiol 88: 431–435

    Google Scholar 

  290. Chen HH, PH Li 1980 Biochemical Changes In Tuber Bearing Solanum Species In Relation To Frost Hardiness During Cold Acclimation. Plant Physiol 66: 414–421

    Article  Google Scholar 

  291. Li PH, CJ Weiser 1966 The Relation Of Cold Resistance To The Status Of Phosphorus And Certain Metabolites In Redosier Dogwood ( Cornus stolonifera Michx. ). Plant Cell Physiol 7: 475–484

    Google Scholar 

  292. Pomeroy MK, D Siminovitch, F Wightman 1970 Seasonal Biochemical Changes In The Living Bark And Needles Of Red Pine ( Pinus resinosa) in relation to adaptation to freezing. Can J Bot 48: 953–967

    Google Scholar 

  293. Hwei-Hwang C, PH Li, ML Brenner 1983 Involvement Of Abscissic Acid In Potato Cold Acclimation. Plant Physiol 71: 362–365

    Article  Google Scholar 

  294. Kacperska-Palacz A 1978 Mechanism Of Cold Acclimation In Herbaceous Plants. In Plant Cold Hardiness And Freezing Stress ( PH Li, A Sakai, eds.). Academic Press, New York, pp 139–152

    Chapter  Google Scholar 

  295. Rikin A, M Walkman, AE Richmond, A Dovrat 1975 Hormonal Regulation Of Morphogenesis And Cold-Resistance: I. Modifications By Abscissic Acid And By Gibberllic Acid In Alfalfa Medicago Sativa L. Seedlings. J Exp Bot 26: 175–183

    Google Scholar 

  296. Waldman M, A Rikin, A Dovrat, AE Richmond 1975 Hormonal Morphogenesis And Cold Resistance. II. Effect Of Cold Acclimation And Exogenous Abscissic Acid On Gibberellic Acid And Abscissic Acid Activities In Alfalfa ( Medicago sativa L.) seedlings. J Exp Bot 26: 853–859

    Article  Google Scholar 

  297. Dale J, WF Campbell 1981 Response Of Tomato Plants To Stress Temperatures: Increase In Abscissic Acid Concentrations. Plant Physiol 67: 26–29

    Google Scholar 

  298. Nakamoto H, GE Edwards 1983 Influence Of Oxygen And Temperature On The Dark Inactivation Of Pyruvate, Orthophosphate Dikinase And Nadp-Malate Dehydrogenase In Maize. Plant Physiol 71: 568–573

    Article  Google Scholar 

  299. Key JL, CY Lin, YM Chen 1981 Heat Shock Proteins Of Higher Plants. Proc Natl Acad Sci Usa 78: 3526–3530

    Article  ADS  Google Scholar 

  300. Dougall DK, S Labrake, GH Whitten 1983 Growth And Anthocyanin Accumulation Rates Of Carrot Suspension Cultures Grown With Excess Nutrients After Semicontinuous Culture With Different Limiting Nutrients At Several Dilution Rates, Phs, And Temperatures. Biotechnol Bioeng 25: 581–594

    Google Scholar 

  301. Dougall DK, S Labrake, GH Whitten 1983 The Effects Of Limiting Nutrients, Dilution Rate, Culture, And Temperature On The Yield Constant And Anthocyanin Accumulation Of Carrot Cells Grown In Semicontinuous Chemostat Cultures. Biotechnol Bioeng 25: 569–579

    Google Scholar 

  302. Dobberstein RH, EJ Staba 1966 Chlorophyll Production In Japanese Mint Suspension Cultures. Lloydia 29: 50–57

    Google Scholar 

  303. Yamada Y, Y Hara, H Katagi, M Senda 1980 Protoplast Fusion. Effect Of Low Temperature On The Membrane Fluidity Of Cultured Cells. Plant Physiol 65: 1099–1102

    Google Scholar 

  304. Wagner F, H Vogelmann 1977 Cultivation Of Plant Tissue Cultures In Bioreactors And Formation Of Secondary Metabolites. In Plant Tissue Culture And Its Biotechnological Application ( W. Barz, E. Reinhard, MH Zenk eds.). Springer-Verlag, Berlin pp 245–252

    Chapter  Google Scholar 

  305. Veliky IA 1977 Effect Of Ph On Tryptophol Formation By Cultured Ipomoea Sp. Plant Cells. Lloydia 40: 482–486

    Google Scholar 

  306. Koul S, A Ahuja, S Grewal 1983 Growth And Alkaloid Production In Suspension Cultures Of Hyoscyamus Muticus As Influenced By Various Cultural Parameters. Planta Med 47: 11–16

    Article  Google Scholar 

  307. Radwan SS, HK Mangold 1975 Lipids In Plant Tissue Cultures. V. Effect Of Environmental Conditions On The Lipids Of Glycine Soja And Brassica Napus Cultures. Chem Phys Lipids 14: 87–91

    Article  Google Scholar 

  308. Hook DD, RMM Crawford (eds.) 1978 Plant Life in Anaerobic Environments, Ann Arbor Sci Publ, Ann Arbor, MI 564 pp

    Google Scholar 

  309. App AA, AN Meiss 1958 Effect Of Aeration On Rice Alcohol Dehydrogenase. Arch Biochem Biophys 77: 181–190

    Article  Google Scholar 

  310. Hageman RH, D Fleher 1960 The Effect Of Anaerobic Environment On The Activity Of Alcohol Dehydrogenase And Other Enzymes Of Corn Seedlings. Arch Biochem Biophys 87: 203–209

    Article  Google Scholar 

  311. Crawford RMM, M Mcmanmon 1968 Inductive Response Of Alcohol And Malic Dehydrogenase In Relation To Flooding Tolerance In Roots. J Exp Bot 19: 435–441

    Article  Google Scholar 

  312. Weber N, HK Mangold 1982 Metabolism Of Long-Chain Alcohols In Suspension Cultures Of Soya And Rape. Planta 155: 225–230

    Article  Google Scholar 

  313. Radwan SS, HK Mangold, F Spener 1974 Lipids In Plant Tissue Cultures. Iii. Very Long-Chain Fatty Acids In The Lipids Of Callus Cultures And Suspension Cultures. Chem Phys Lipids 13: 103–107

    Google Scholar 

  314. Wickremasinghe RL, T Swain, JL Goldstein 1963 Accumulation Of Amino Acids In Plant Cell Tissue Cultures. Nature (London) 199: 1302–1303

    Article  ADS  Google Scholar 

  315. Staba EJ 1980 Secondary Metabolism And Biotransformation. In Plant Tissue Culture As A Source Of Biochemicals ( EJ Staba ed.). CRC Press, Boca Raton, FL pp 59–97

    Google Scholar 

  316. Crawford RMM 1978 Metabolic Adaptations To Anoxia. In Plant Life In Anaerobic Environments ( DD Hook, RMM Crawford, eds.). Ann Arbor Sci Publ, Ann Arbor, MI pp 119–136

    Google Scholar 

  317. Chirkova TV 1978 Some Regulatory Mechanisms Of Plant Adaptation To Temporal Anaerobiosis. In Plant Life In Anaerobic Environments ( DD Hook, RMM Crawford eds.). Ann Arbor Sci Publ, Ann Arbor, MI pp 137–154

    Google Scholar 

  318. Leblova S 1978 Pyruvate Conversions In Higher Plants During Anaerobiosis. In Plant Life In Anaerobic Environments ( DD Hook, RMM Crawford eds.). Ann Arbor Sci Publ, Ann Arbor, MI pp 119–136

    Google Scholar 

  319. Cossins EA 1978 Ethanol Metabolism In Plants. In Plant Life In Anaerobic Environments ( DD Hook, RMM Crawford eds.). Ann Arbor Sci Publ, Ann Arbor, MI pp 169–202

    Google Scholar 

  320. Cameron DS, EA Cossins 1967 Studies Of Intermediary Metabolism In Germinating Pea Cotyledons. The Pathway Of Ethanol Metabolism And The Role Of The Tricarboxylic Acid Cycle. Biochem J 105: 323–331

    Google Scholar 

  321. Wager HG 1983 The Labelling Of Glueose-6-Phosphate In Pea Slices Supplied With Llfc Glucose, And The Assessment Of The Respiratory Pathways In Air, In 10% C02 And In 2% 02 In N. J Exp Bot 34: 211–220

    Google Scholar 

  322. Malmstrom BG 1982 Enzymology Of Oxygen. Ann Rev Biochem 51: 21–59

    Article  Google Scholar 

  323. Bonnet R 1981 Oxygen Activation And Tetrapyroles. In Essays In Biochemistry, ( PN Campbell, RD Marshall eds.). Academic Press, New York, pp 1–51

    Google Scholar 

  324. Miller CO 1972 Modification Of The Cytokinin Promotion Of Deoxyisoflavone Synthesis In Soybean Tissue. Plant Physiol 49: 310–313

    Article  Google Scholar 

  325. See Reference 9

    Google Scholar 

  326. Hahlbrock K, H Ragg 1975 Light-Induced Changes Of Enzyme Activities In Parsley Cell Suspension Cultures. Arch Biochem Biophys 166: 41–46

    Article  Google Scholar 

  327. De Klerk-Kiebert YM, TJA Kneppers, LHW Van Der Plas 1982 Influence Of Chloramphenicol On Growth And Respiration Of Soybean ( Glycine max L.) suspension cultures. Physiol Plant 55: 98–102

    Google Scholar 

  328. Noe W, C Langebartels, HU Scitz 1980 Anthocyanin Accumulation And Pal Activity In Suspension Culture Of Daucus Carota. Planta 149: 283–287

    Article  Google Scholar 

  329. Noe W, HU Scitz 1982 Induction Of De Novo Synthesis Of Phenylalanine Ammonialyase By L-A-Aminooxy-8-Phenylpropionic Acid In Suspension Cultures Of Daucus Carota. Planta 154: 454–458

    Article  Google Scholar 

  330. Berlin J, KG Kokoschke, K-H Knobloch 1981 Selection Of Tobacco Cell Lines With High Yields Of Cinnamoyl Putrescines. Plant Med 42: 173–180

    Article  Google Scholar 

  331. Berlin J, L Wittle, J Hammer, Kg Kukoschke, A Zimmer, D Pape 1982 Metabolism Of P-Fluorophenylalanine In P-Fluorophenylalanine Sensitive And Resistant Tobacco Cell Cultures. Planta 155: 244–250

    Article  Google Scholar 

  332. Berlin J, K-H Knobloch, G Hogle, L Witte 1982 Biochemical Characterization Of Two Tobacco Cell Lines With Diffeent Levels Of Cinnamoyl Putrescines. J Nat Prod 45: 83–87

    Article  Google Scholar 

  333. Lea PJ, RD Norris 1976 The Use Of Amino Acid Analogues In Studies On Plant Metabolism. Phytochemistry 15: 585–595

    Article  Google Scholar 

  334. Widholm JM 1980 Selection Of Plant Cell Lines Which Accumulate Certain Compounds. In Plant Tissue Culture As A Source Of Biochemicals ( EJ Staba ed.). CRC Press, Boca Raton, FL pp 99–112

    Google Scholar 

  335. Berlin J 1980 P-Fluorophenylalanine Resistant Cell Lines Of Tobacco. Z Pflanzenphysiol 97: 317–324

    Google Scholar 

  336. Palmer JE, JM Widholm 1975 Characterization Of Carrot And Tobacco Cell Cultures Resistant To P-Fluorophenylalanine. Plant Physiol 56: 233–238

    Article  Google Scholar 

  337. Gathercole RWE, HE Street 1976 Isolation, Stability And Biochemistry Of P-Fluorophenylalanine Resistant Cell Line Of Acer Pseudoplatanus L. New Phytol 77: 29–41

    Google Scholar 

  338. Gathercole RWO, HE Street 1978 A P-Fluorophenylalanine Resistant Cell Line Of Sycamore With Increased Contents Of Phanylalanine, Tyrosine And Phenolics. Z Pflanzenphysiol 89: 283–287

    Google Scholar 

  339. Berlin J, JM Widholm 1977 Correlation Between Phenylalanine Ammonia Lyase Activity And Phenolic Biosynthesis In P-Fluorophenylalanine-Sensitive And Resistant Tobacco And Carrot Tissue Cultures. Plant Physiol 59: 550–553

    Article  Google Scholar 

  340. Berlin J, JM Widholm 1978 Metabolism Of Phenylalanine And Tyrosine In Tobacco Cell Lines Resistant And Sensitive To P-Fluorophenylalanine. Phytochemistry 17: 65–68

    Article  Google Scholar 

  341. See Reference 334

    Google Scholar 

  342. Widholm JM 1972 Anthranilate Synthetase From 5-Methytryptophan-Susceptible And Resistant Cultured Daucus Carota Cells. Biochim Biophys Acta 279: 48–57

    Article  Google Scholar 

  343. Widholm JM 1972 Cultured Nicotiana Tabacum Cells With An Altered Anthranilate Synthase Which Is Less Sensitive To Feedback Inhibition. Biochim Biophys Acta 261: 52–58 343A. Wood, Rks (ed.) 1982 Active Defense Mechanisms in Plants. Plenum Press, New York, 381 pp

    Google Scholar 

  344. Bailey JA, JW Mansfield (eds.) 1982 Phytoalexins. Blackie and Son Ltd., Glasgow, 334 pp

    Google Scholar 

  345. Bell AA, ME Mace 1981 Biochemistry And Physiology Of Resistance. Jen Fungal Wilt Diseases Of Plants. (ME Mace, AA Bell, CH Beckman, eds.). Academic Press, New York, pp 431–486

    Google Scholar 

  346. Cruickshank IAM 1977 A Review Of The Role Of Phytoalexins In Disease Resistance Mechanisms. In Natural Products And The Protection Of Plants ( GB Marini-Bettolo, ed.), Elsevier, Amsterdam, pp 509–561

    Google Scholar 

  347. Stoessl A 1980 Phytoalexins-A Biogenetic Perspective. Phytopath Z 99: 251–272

    Article  Google Scholar 

  348. Friend J 1977 Biochemistry Of Plant Pathogens. In Plant Biochemistry II, ( DN Northcote, ed.), University Park Press, Baltimore, MD pp 141–182

    Google Scholar 

  349. Friend J 1981 Plant Phenolics* Lignification And Plant Disease. Progr Phytochem 7: 197–261

    Google Scholar 

  350. West CA 1981 Fungal Elicitors Of The Phytoalexin Response In Higher Plants. Naturwissenschaften 68: 447–457

    Article  ADS  Google Scholar 

  351. Dixon RA, Ds Bendall 1978 Changes In Phenolic Compounds Associated With Phaseollin Production In Cell Suspension Cultures Of Phaseolus Vulgaris. Physiol Plant Pathol 13: 283–294

    Article  Google Scholar 

  352. Dixon RA, DS Bendall 1978 Changes In The Levels Of Enzymes Of Phenylpropanoid And Isoflavonoid Synthesis During Phaseollin Production In Cell Suspension Cultures Of Phaseolus Vulgaris. Physiol Plant Pathol 13: 295–306

    Article  Google Scholar 

  353. Boder GB, M Gorman, IS Johnson, PJ Simpson 1964 Tissue Culture Studies Of Catharanthus Roseus Crown Gall. Lloydia 27: 328–333

    Google Scholar 

  354. Brown SA, M Tenniswood 1974 Aberrant Coumarin Metabolism In Crown Gall Tissues Of Tobacco. Can J Bot 52: 1091–1094

    Article  Google Scholar 

  355. Ikeda T, T Matsumoto, M Noguchi 1976 Formation Of Ubiquinone By Tobacco Plant Cells In Suspension Culture. Phytochemistry 15: 568–569

    Article  Google Scholar 

  356. Audisio S, N Bagni, DS Fracassini 1976 Polyamines During The Growth In Vitro Of Nicotiana Glauca R. Grah. Habituated Tissue. Z Pflanzenphysiol 77: 146–151

    Google Scholar 

  357. Speranza A, N Bagni 1977 Putrescine Biosynthesis In Agrobacterium Tumefaciens And In Normal And Crown Gall Tissues Of Scorzonera Hispanica L. Z Pflanzenphysiol 81: 226–233

    Google Scholar 

  358. Bagni N, DS Fracassini, E Corsini 1972 Tumors Of Scorzonera Hispanica: Their Content In Polyamines. Z Pflanzenphysiol 67: 19–23

    Google Scholar 

  359. Weete JD, S Venketeswaran, JL Laseter 1971 Two Populations Of Aliphatic Hydrocarbons Of Teratoma And Habituated Tissue Culture Of Tobacco. Phytochemistry 10: 939–943

    Article  Google Scholar 

  360. Wood HN, AC Braun 1961 Studies On The Regulation Of Certain Essential Biosynthetic Systems In Normal And Crowngall Tumor Cells. Proc Nat Acad Sci Usa 47: 1907–1913

    Article  ADS  Google Scholar 

  361. Roberts WP 1982 The Molecular Basis Of Crown Gall Induction. Int Rev Cytol 80: 63–92

    Article  Google Scholar 

  362. Kahl G, JS Schell Eds 1982 Molecular Biology Of Plant Tumors. Academic Press, New York, 615 Pp

    Google Scholar 

  363. Spurr HW, AC Hildebrandt, AJ Riker 1967 Ascorbic Acid Oxidase And Tyrosinase Activities In Relation To Crown-Gall Development. Phytopathology 52: 1079–1086

    Google Scholar 

  364. Meins F 1982 Habituation Of Cultured Plant Cells. In Molecular Biology Of Plant Tumors ( G. Kahl, JS Schell, eds.). Academic Press, New York, pp 3–31

    Google Scholar 

  365. Tempe J, P Guyon, D Tepfer, A Petit 1979 The Role Of Opines In The Ecology Of The T. Plasmids Of Medical, Environmental And Commercial Importance (KN Timmis, A Puhler, eds.), Elsevier/North Holland Biomedical Press, Amsterdam, pp 353–372

    Google Scholar 

  366. Dixon RA, PM Dey, MA Lawton, CJ Lamb 1983 Phytoalexin Induction In French Bean. Intercellular Transmission Of Elicitation In Cell Suspension Cultures And Hypocotyl Sections Of Phaseollus Vulgaris. Plant Physiol 71: 251–256

    Article  Google Scholar 

  367. Dixon RA, PM Dey, DL Murphy, IM Whitehead 1981 Dose Responses For Colletotrichum Lindemuthianum Elicitor-Mediated Enzyme Induction In French Bean Cell Suspension Cultures. Planta 151: 272–280

    Article  Google Scholar 

  368. Dixon RA, KW Fuller 1977 Characterization Of Components From Culture Filtrates Of Botrytis Cinerea Which Stimulate Phaseollin Biosynthesis In Phaseolus Vulgaris Cell Suspension Cultures. Physiol Plant Pathol 11: 287–296

    Article  Google Scholar 

  369. Dixon RA, KW Fuller 1978 Effects Of Growth Substances On Non-Induced And Botrytis Cinerea Culture Filtrate-Induced Phaseollin Production In Phaseollus Vulgaris Cell Suspension Cultures. Physiol Plant Pathol 12: 279–288

    Article  Google Scholar 

  370. Ebel J, AR Ayers, PA Albersheim 1976 Host-Pathogen Interactions. XII. Responses Of Suspension-Cultured Soybean Cells To The Elicitor Isolated From Phytophthora Megasperma Var. Sojae, A Fungal Pathogen Of Soybeans. Plant Physiol 57: 775–779

    Google Scholar 

  371. Eresk T, I Sziraki 1980 Production Of Sesquiterpene Phytoalexins In Tissue Culture Callus Of Potato Tubers. Phytopath Z 97: 364–368

    Article  Google Scholar 

  372. Hahlbrock K, CJ Lamb, C Purwin, J Ebel, E Fautz, E Schäfer 1981 Rapid Response Of Suspension-Cultured Parsley Cells To The Elicitor From Phytophthora Megasperma Var. Sojae. Plant Physiol 67: 768–773

    Article  Google Scholar 

  373. Gustine DL, RT Sherwood 1978 Regulation Of Phytoalexin Synthesis In Jackbean Callus Cultures. Stimulation Of Phenylalanine Ammonia-Lyase And O-Methyltransferase. Plant Physiol 61: 226–230

    Article  Google Scholar 

  374. Kurosaki F, A Nishi 1983 Isolation And Antimicrobial Activity Of The Phytoalexin 6-Methoxymellein From Cultured Carrot Cells. Phytochemistry 22: 669–672

    Article  Google Scholar 

  375. Zahringer U, E Scaller, H Grisebach 1981 Induction Of Phytoalexin Synthesis In Soybean. Structure And Reactions Of Naturally Occurring And Enzymatically Prepared Prenylated Pterocarpans From Elicitor-Treated Cotyledons And Cell Cultures Of Soybean. Z Naturforsch 36 (c): 234–241

    Google Scholar 

  376. Hahlbrock K, F Kreuzaler, H Ragg, E Fautz, DN Kuhn 1982 Regulation Of Flavonoid And Phytoalexin Accumulation Through Mrna And Enzyme Induction In Cultured Plant Cells. Hoppe-Seylers Z Physiol Chem 363: 121–122

    Google Scholar 

  377. Rowan DD, PE Mac Donald, RA Skipp 1983 Antifungal Stress Metabolites From Solanum Aviculare. Phytochemistry 22: 2102–2104

    Google Scholar 

  378. Strasser H, KG Tietjen, K Himmelspach, U Matern 1983 Rapid Effect Of An Elicitor On Uptake And Intracellular Distribution Of Phosphate In Cultured Parsley Cells. Plant Cell Reports 2: 140–143

    Article  Google Scholar 

  379. Tietjen KG, D Hunkler, U Matern 1983 Differential Response Of Cultured Parsley Cells To Elicitors From Two Non-Pathogenic Strains Of Fungi. 1. Identification Of Induced Products As Coumarin Derivatives. Eur J Biochem 131: 401–407

    Article  Google Scholar 

  380. Tietjen Kg, U Matern 1983 Differential Response Of Cultured Parsley Cells To Elicitors From Two Non-Pathogenic Strains Of Fungi. 2. Effects On Enzyme Activities. Eur J Biochem 131: 409–413

    Google Scholar 

  381. Miller SA, LB Graves, DP Maxwell 1981 (Abstract) Hyphal development and phytoalexin accumulation in alfalfa tissue culture-Phytophtohora megasperma system. Phytopathol 71: 895

    Google Scholar 

  382. Helgeson JP, AD Budde, GT Haberlach 1978 (Abstract) Capsidiol-phytoalexin produced by tobacco callus tissues. Plant Physiol Suppl 61: 58

    Google Scholar 

  383. Budde AD, JP Helgeson 1981 (Abstract). Phytoalexins in tobacco callus tissues challenged by zoospores of Phytophthora parasitica var. nicotianae. Phytopathol 71: 206

    Google Scholar 

  384. Eilert U, B Engel, E Reinhard, B Wolters 1983 Acridone Epoxides In Cell Cultures Of Ruta Species. Phytochemistry 22: 14–15

    Google Scholar 

  385. Teitjen K, U Matern 1981 (Abstract) Mode of action of Alternaria carthami toxin in Safflower (Carthamus tinctorius L.). Phytochem Soc N Amer Newsletter, July, p. 12

    Google Scholar 

  386. Fujimori TH, H Tanaka, K Kato 1983 Stress compounds in tobacco callus infiltrated by Pseudomonas solanacearum. Phytochemistry 22: 1038

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Botany, University of Toronto, M5S 1A1, Toronto, Ontario, Canada

    Frank DiCosmo

  2. Department of Botany, University of British Columbia, V6T 2B1, Vancouver, British Columbia, Canada

    G. H. N. Towers

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  1. The University of Arizona, Tucson, Arizona, USA

    Barbara N. Timmermann  & Cornelius Steelink  & 

  2. Washington State University, Pullman, Washington, USA

    Frank A. Loewus

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DiCosmo, F., Towers, G.H.N. (1984). Stress and Secondary Metabolism in Cultured Plant Cells. In: Timmermann, B.N., Steelink, C., Loewus, F.A. (eds) Phytochemical Adaptations to Stress. Recent Advances in Phytochemistry, vol 18. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1206-2_5

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