Adrenal Medulla Gangliosides

  • Michiko Sekine
  • Toshio Ariga
  • Tadashi Miyatake
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 174)


The adrenal medulla, which belongs to the autonomic nervous system, contains high amounts of gangliosides.1, 2 Ledeen and co-workers isolated three monosialogangliosides and two disialogangliosides from bovine adrenal medulla and determined their structures as N-acetyl GM3, N-glycolyl GM3, GM1, GDla and GDla containing 1 mole each of N-acetyl- and N-glycolylneuraminic acid (Table 1).1,3 Additionally, three disialogangliosides and four trisialogangliosides were recently found in bovine adrenal medulla (Table 1).4, 5


Sialic Acid Adrenal Medulla Thin Layer Chromatogram Chromaffin Granule Bovine Adrenal Medulla 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Michiko Sekine
    • 1
  • Toshio Ariga
    • 1
  • Tadashi Miyatake
    • 2
  1. 1.Department of Biochemistry and MetabolismTokyo Metropolitan Institute of Medical Science HonkomagomeBunkyo-ku, Tokyo 113Japan
  2. 2.Department of Neurology Brain Research InstituteNiigata UniversityNiigata 951Japan

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