Adrenal Medulla Gangliosides

Abstract

The adrenal medulla, which belongs to the autonomic nervous system, contains high amounts of gangliosides.^{1, 2} Ledeen and co-workers isolated three monosialogangliosides and two disialogangliosides from bovine adrenal medulla and determined their structures as N-acetyl GM3, N-glycolyl GM3, GM1, GDla and GDla containing 1 mole each of N-acetyl- and N-glycolylneuraminic acid (Table 1).^1,3 Additionally, three disialogangliosides and four trisialogangliosides were recently found in bovine adrenal medulla (Table 1).^{4, 5}