Structure Analysis of Glycosphingolipids Using Fast Atom Bombardment (FAB) Techniques

  • Heinz Egge
  • Jasna Peter-Katalinic
  • Peter Hanfland
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 174)


The development of fast atom bombardment mass spectrometry1 (FAB MS) and high field and high resolution magnetic sector mass spectrometry2 have disclosed new dimensions in the analysis and sequencing of polar nonvolatile compounds of vital biological importance such as oligonucleotides3, peptides,4 and glycoconjugates5 with molecular weights up to 8000 daltons.


Fast Atom Bombard Sialic Acid Residue Fast Atom Bombardment Mass Spectrometry Fast Atom Bombard Mass Spectrum Fast Atom Bombard 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    M. Barber, R. S. Bordoli, R. D. Sedgwick and A. N. Tyler, Fast atom bombardment of solids as an ion source in mass spectrometry, Nature 293:270 (1981).CrossRefGoogle Scholar
  2. 2.
    A. Dell and H. R. Morris, Fast atom bombardment-high field magnet mass spectrometry of 6000 dalton polypeptides, Biochem. Biophys. Res. Commun. 106:1456 (1982).PubMedCrossRefGoogle Scholar
  3. 3.
    D. H. Williams, C. Bradley, G. Bojesen, S. Santikarn and L.C.E. Taylor, Fast atom bombardment mass spectrometry: a powerful technique for the study of polar molecules, J. Am. Chem. Soc. 103:5700 (1981).CrossRefGoogle Scholar
  4. 4.
    M. Barber, R. S. Bordoli, G. J. Elliott, N. J. Horoch and B. N. Green, Fast atom bombardment mass spectrometry of human pro-insulin, Biochem. Biophys. Res. Commun. 110:753 (1983).PubMedCrossRefGoogle Scholar
  5. 5.
    A. Dell, J. E. Oaks, H. R. Morris and H. Egge, Structure determination of carbohydrates and glycosphingolipids by fast atom bombardment mass spectrometry, Int. J. Mass Spectrom. & Ion Phys. 46:415 (1983).CrossRefGoogle Scholar
  6. 6.
    R. Kuhn and H. Egge, Uber Ergenbnisse der Permethylierung der Ganglioside GI and GII, Chem. Ber. 96:3338 (1963).CrossRefGoogle Scholar
  7. 7.
    P. Hanfland, H. Egge, U. Dabrowski, S. Kuhn, D. Roelcke and J. Dabrowski, Isolation and characterization of an I-active ceramide decasaccharide from rabbit erythrocyte membranes, Biochemistry 20:5310 (1981).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Heinz Egge
    • 1
  • Jasna Peter-Katalinic
    • 1
  • Peter Hanfland
    • 2
  1. 1.Institute for Physiological ChemistryUniversity of BonnGermany
  2. 2.Institute for Experimental Hematology and Blood-transfusionUniversity of BonnGermany

Personalised recommendations