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Structure Analysis of Glycosphingolipids Using Fast Atom Bombardment (FAB) Techniques

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Ganglioside Structure, Function, and Biomedical Potential

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 174))

Abstract

The development of fast atom bombardment mass spectrometry1 (FAB MS) and high field and high resolution magnetic sector mass spectrometry2 have disclosed new dimensions in the analysis and sequencing of polar nonvolatile compounds of vital biological importance such as oligonucleotides3, peptides,4 and glycoconjugates5 with molecular weights up to 8000 daltons.

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References

  1. M. Barber, R. S. Bordoli, R. D. Sedgwick and A. N. Tyler, Fast atom bombardment of solids as an ion source in mass spectrometry, Nature 293:270 (1981).

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  2. A. Dell and H. R. Morris, Fast atom bombardment-high field magnet mass spectrometry of 6000 dalton polypeptides, Biochem. Biophys. Res. Commun. 106:1456 (1982).

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  3. D. H. Williams, C. Bradley, G. Bojesen, S. Santikarn and L.C.E. Taylor, Fast atom bombardment mass spectrometry: a powerful technique for the study of polar molecules, J. Am. Chem. Soc. 103:5700 (1981).

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  4. M. Barber, R. S. Bordoli, G. J. Elliott, N. J. Horoch and B. N. Green, Fast atom bombardment mass spectrometry of human pro-insulin, Biochem. Biophys. Res. Commun. 110:753 (1983).

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  5. A. Dell, J. E. Oaks, H. R. Morris and H. Egge, Structure determination of carbohydrates and glycosphingolipids by fast atom bombardment mass spectrometry, Int. J. Mass Spectrom. & Ion Phys. 46:415 (1983).

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  6. R. Kuhn and H. Egge, Uber Ergenbnisse der Permethylierung der Ganglioside GI and GII, Chem. Ber. 96:3338 (1963).

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  7. P. Hanfland, H. Egge, U. Dabrowski, S. Kuhn, D. Roelcke and J. Dabrowski, Isolation and characterization of an I-active ceramide decasaccharide from rabbit erythrocyte membranes, Biochemistry 20:5310 (1981).

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Author information

Authors and Affiliations

  1. Institute for Physiological Chemistry, University of Bonn, Germany

    Heinz Egge & Jasna Peter-Katalinic

  2. Institute for Experimental Hematology and Blood-transfusion, University of Bonn, Germany

    Peter Hanfland

Authors
  1. Heinz Egge
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  2. Jasna Peter-Katalinic
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  3. Peter Hanfland
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Editor information

Editors and Affiliations

  1. Albert Einstein College of Medicine, Bronx, New York, USA

    Robert W. Ledeen  & Kunihiko Suzuki  & 

  2. Yale University School of Medicine, New Haven, Connecticut, USA

    Robert K. Yu

  3. New York State Psychiatric Institute, New York, New York, USA

    Maurice M. Rapport

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© 1984 Plenum Press, New York

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Egge, H., Peter-Katalinic, J., Hanfland, P. (1984). Structure Analysis of Glycosphingolipids Using Fast Atom Bombardment (FAB) Techniques. In: Ledeen, R.W., Yu, R.K., Rapport, M.M., Suzuki, K. (eds) Ganglioside Structure, Function, and Biomedical Potential. Advances in Experimental Medicine and Biology, vol 174. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1200-0_5

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  • DOI: https://doi.org/10.1007/978-1-4684-1200-0_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1202-4

  • Online ISBN: 978-1-4684-1200-0

  • eBook Packages: Springer Book Archive

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