Abstract
It is my great privilege to present the opening lecture at this very exciting meeting. The organizer, Dr. Ledeen, suggested a historical outline of glycolipid research as an introduction, and I hope you will allow me to talk freely as I outline some of the thoughts and questions that have occured to me during my 30 years of research in this field.
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References
J. L. W. Thudichum, A treatise on the chemical constitution of the brain, Bailliere, Tindall and Cox, London (1884).
T. Uchida, K. Takahashi, H. Yamaguchi, and Y. Nagai, Localization of galactocerebroside in oligodendrocytes, myelin sheath and choroid plexus, Japan J. Exp. Med. 51:29 (1981).
K. Sakakibara, T. Momoi, T. Uchida, and Y. Nagai, Evidence for association of glycosphingolipid with a colchicine-sensitive microtubule-like cytoskeletal structure of cultured cells, Nature 293:76 (1981).
S. Abrahamsson, B. Dahlen, H. Lofgren, I. Pascher, and S. Sundell, Molecular arrangement and conformation of lipids of relevance to membrane structure, in: “Structure of Biological Membranes”, S. Abrahamsson and I. Pascher, eds., Plenum Press, New York and London (1977).
W. Koch, Zur kenntnis der schwefelverbindugen des nerven systems, Z. Physiol. Chem. 53:496 (1907).
G. Blix, Zur kenntnis der schwefelhaltigen lipoidstoffe des gehirns. Uber cerebronschwefelsaure, Z. Physiol. Chem. 219:82 (1933).
T. Nakayama, Studies on the conjugated lipids. II. On cerebron sulphuric acid, J. Biochem. 38:157 (1951).
S. J. Thannhauser, J. Fellig, and G. Schmidt, The structure of cerebroside sulfuric ester of beef brain, J. Biol. Chem. 215:211 (1955).
T. Yamakawa, N. Kiso, S. Handa, A. Makita, and S. Yokoyama, On the structure of brain cerebroside sulfuric ester and ceramide dihexoside of erythrocytes, J. Biochem. 52:226 (1962).
P. J. Stoffyn and A. Stoffyn, Structure of sulfatides, Biochim. Biophys. Acta 70:218 (1963).
I. Ishizuka, A. Suzuki, and T. Yamakawa, Isolation and characterization of a novel sulfoglycolipid, “Seminolipid”, from boar testis and spermatozoa, J. Biochem. 73:77 (1973).
M. Kates, B. Palamenta, M. B. Perry, and G. A. Adams, A new glycolipid sulfate ester in Halobacterium cutirubrum, Biochim. Biophys. Acta 137:213 (1967).
E. Klenk, Uber die natur der phosphatide und anderer lipoide des gehirns und der leber bei der Niemann-Pickschen Krankheit (12. Mitteilung uber phosphatide), Z. Physiol. Chem. 235:24 (1935).
E. Walz, Uber das vorkommen von kerasin in der normalen rindermilz, Z. Physiol. Chem. 166:210 (1927).
P. A. Levene and K. Landsteiner, On some new lipids, J. Biol. Chem. 75:607 (1927).
E. Klenk, Beitrage zur chemie der lipoidosen (3. Mitteilung) Niemann-Picksche Krankheit und amaurotische Idiotie, Z. Physiol. Chem. 262:128 (1939).
G. Blix, Einige beobachtungen uber eine hexosaminhaltige substanz in der protagonfraktion des gehirns, Skand. Arch. Physiol. 80:46 (1938).
E. Klenk, Uber die ganglioside, eine neue gruppe von zukerhaltigen gehirnlipoiden, Z. Physiol. Chem. 273:76 (1941).
E. Klenk, Neuraminsaure, das spaltprodukt eines neuen gehirnlipoids, Z. Physiol. Chem. 268:50 (1942).
G. Blix, Uber die kohlenhydratgruppen des submaxillarismucins, Z. Physiol. Chem. 240:43 (1936).
T. Yamakawa and S. Suzuki, The chemistry of the lipids of posthemolytic residue or stroma of erythrocytes. III. On the structure of hemataminic acid, J. Biochem. 39:175 (1952).
E. Klenk, H. Faillard, F. Weygand, and H. H. Schone, Untersuchungen uber die konstitution der neuraminsaure, Z. Physiol. Chem. 304:35 (1956).
A. Gottshalk, Structural relationship between sialic acid, neuraminic acid and 2-carboxy-pyrrole, Nature (London) 176:881 (1955).
L. Svennerholm, Partition chromatography of brain in gangliosides on cellulose, Acta Chem. Scand. 8:1108 (1954).
R. Kuhn and H. Wiegandt, Die konstitution der ganglioside GII, GIII und GIV, Z. Naturforsch. 18b:541 (1963).
T. Yamakawa and S. Suzuki, The chemistry of the lipids of posthemolytic residue or stroma of erythrocytes. I. Concerning the ether-insoluble lipids of lyophilized horse blood stroma, J. Biochem. 38:199 (1951).
E. Klenk and K. Lauenstein, Uber die zuckerhaltigen lipoid der formbestandteile des menschlichen blutes, Z. Physiol. Chem. 288:220 (1951).
T. Yamakawa and S. Suzuki, The chemistry of the lipids of posthemolytic residue or stroma of erythrocytes. III. Globosides, the sugar-containing lipid of human blood stroma, J. Biochem. 39:393 (1952).
T. Yamakawa, Glycolipids of mammalian red blood cells, in: “Lipoide” Shutte, ed., 16. Colloquium der Gesell. Physiol. Chem. in Mosbach. (1965).
T. Yamakawa and Y. Nagai, Glycolipid at the cell surface and their biological functions, Trends Biochem. Sci. 3:128 (1978).
T. Yamakawa and T. Iida, Immunological study on the red blood cells. I. Globoside as the agglutinogen of the ABO system on erythrocytes, Japan J. Exp. Med. 23:327 (1953).
B. Siddiqui and S. Hakomori, A revised structure for the Forssman glycolipid hapten, J. Biol. Chem. 246:5766 (1971).
M. Naiki and D. M. Marcus, An immunochemical study of the human blood group Il, P, and Pk glycosphingolipid antigens, Biochemistry 14:4837 (1975).
T. Feizi, E. A. Kabat, G. Vicari, B. Anderson, and W. L. Marsh, Immunological studies on blood groups, XIX. The I antigen complex: Specificity differences among anti-I sera revealed by quantitative precipitin studies; Partial structure of the I determinant specific for one anti-I serum, J. Immunol. 106:1578 (1971).
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© 1984 Plenum Press, New York
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Yamakawa, T. (1984). Wonders in Glycolipids — A Historical View. In: Ledeen, R.W., Yu, R.K., Rapport, M.M., Suzuki, K. (eds) Ganglioside Structure, Function, and Biomedical Potential. Advances in Experimental Medicine and Biology, vol 174. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1200-0_1
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