Abstract
In shock and during renal transplantation, kidneys may be exposed to different periods of reduced blood supply. A reversible or irreversible impairment in renal functions may occur. It is of clinical and theoretical interest to obtain more detailed information on the ability of kidney cells to recover after different periods of normothermic anoxia. We compared the recovery of tubular cell functions such as PAH transport, K+ accumulation, and gluconeogenesis after different periods of normothermic anoxia in either a physiological Krebs-Ringer-Bicarbonate (KRB) solution or in a medium of “intracellular” composition (a modified Collins’ solution) Additionally, protein loss and enzyme release from tubular cells were measured in both incubation media during anoxia.
Supported by the Deutsche Forschungsgemeinschaft
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© 1984 Plenum Press, New York
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Gronow, G., Meya, F., Weiss, C. (1984). Studies on the Ability of Kidney Cells to Recover after Periods of Anoxia. In: Lübbers, D.W., Acker, H., Leniger-Follert, E., Goldstrick, T.K. (eds) Oxygen Transport to Tissue-V. Advances in Experimental Medicine and Biology, vol 169. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1188-1_53
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DOI: https://doi.org/10.1007/978-1-4684-1188-1_53
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-1190-4
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