Abstract
It is known that the blood flow in different organs is influenced by the oxygen tension in the blood or in the perfusate, Höper and Kessler (1981) presented evidence that the oxidase involved in this mechanism is MAO-B, an enzyme located in the outer mitochondrial membrane. At the time the question was still open as to whether or not these O2-dependent flow changes occur after the respiratory chain becomes reduced or not.
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References
Coburn, C.F., Grubb, B., and Aronson, R.D., 1979, Effect of cyanide on oxygen tension-dependent mechanical tension in rabbit aorta, Circ. Res., 44: 368–378.
Fay, F.S., and Jübsis, F.F., 1972, Guinea pig ductus arteriosus. III. Light absorption changes during response to O2, Am. J. Physiol., 223: 588–595.
Höper, J., and Kessler, M., 1981, Po2 and sodium dependent mechanism regulating liver blood flow, in: “Oxygen Transport to Tissue”, Adv. Physiol. Sci., Vol. 25, A.G.B. Kovách, E. Dóra, M. Kessler, I.A. Silver, eds., Pergamon Press, Akadémiai Kiadó, Budapest, pp. 163–164.
Höper, J., and Kessler, M., 1982, Constant pressure perfusion of the isolated rat liver: local oxygen supply and metabolic function, Microcirculation, submitted for publication.
Ji, S., Chance, B., Nishiki, K., Smith, T., and Rich, T., 1979, Micro-light guides: a new method for measuring tissue fluorescence and reflectance, Am. J. Physiol. Cell Physiol., 52:C144-C156.
Miller, L.L., Bly, C.G., Watson, M.L., and Bale, W.F., 1951, The dominant role of the liver in plasma protein synthesis. A direct study of the isolated perfused rat liver with the aid of lysine-E-C14, J. Exp. Med., 94: 431–453.
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© 1984 Plenum Press, New York
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Höper, J. (1984). Correlation Between the Redox State of NAD(P)H and Total Flow in the Perfused Rat Liver. In: Lübbers, D.W., Acker, H., Leniger-Follert, E., Goldstrick, T.K. (eds) Oxygen Transport to Tissue-V. Advances in Experimental Medicine and Biology, vol 169. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1188-1_52
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DOI: https://doi.org/10.1007/978-1-4684-1188-1_52
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