Abstract
The curve presenting the relation between oxygen consumption (V̇o2) and blood flow (BF) can be divided into two parts (see Fig. 1). The first one shows a proportionality between the values, supporting the hypothesis of a metabolic control of blood flow. In the second portion a distinct saturation of oxygen consumption is reached, A variation in O2 consumption is then possible independent of flow, thereby changing the amount of O2 extraction. In this upper range a metabolic control of blood flow becomes insufficient to explain changes in the horizontal course of the pressure-flow curve, generally called “autoregulation of blood flow” (see Fig. 3).
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References
Bartels, H., and Harms, H., 1959, Sauerstoffdissoziationskurven des Blutes von Säugetieren, Pflügers Arch. Ges. Physiol., 268: 334–365.
Granger, H.J., and Shepherd, A.P., 1979, Dynamics and control of the microcirculation, in: “Advances in Biomedical Engineering”, Vol. 7, J.H.V. Brown, ed., Academic Press, New York, pp. 1–63.
Hamar, J., Ligeti, L., Kovach, A.G.B., Tkachenko, B.I., Ovsjannikov, V., and Tcherniavskaja, G.V., 1978, Blood supply and O2 consumption of the small intestine in low flow, Acta Physiol. Acad. Sci. Hung., 52: 351–390.
Johnson, P.C., 1964, Origin, localisation and homeostatic significance of autoregulation in the intestine, Circ. Res., 15, Suppl. 1: 225–232.
Kvietys, P.R., and Granger, D.N., 1982, Relation between intestinal blood flow and oxygen uptake, Am. J. Physiol., 242: G202–208.
Lutz, J., 1966, fiber veno-vasomotorische Gefäßreaktionen im Mesen-terialkreislauf der Katze, Pflügers Arch. Ges. Physiol., 287: 330–344.
Lutz, J., 1969, Hämodynamisehe Eigenschaften und Gefäßreaktionen der intestinalen Strombahn, Arch. Kreislaufforsch., 59: 99–152.
Lutz, J., Henrich, H., and Bauereisen, E., 1975, Oxygen supply and uptake in the liver and the intestine, Pflügers Arch., 360: 7–15.
Mellander, S., and Johansson, B., 1968, Control of resistance, exchange and capacitance functions in the peripheral circulation, Pharmacol. Rev., 20: 117–196.
Öhman, V., 1976, Blood flow and oxygen consumption in the feline small intestine; responses to artificial distension and intestinal obstruction, Acta Chir. Scand., 142: 329–333.
Shepherd, A.P., 1982, Metabolic control of intestinal oxygenation and blood flow, Fed. Proc, 41: 2084–2089.
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© 1984 Plenum Press, New York
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Lutz, J. (1984). Flow Dependence and Independence of Oxygen Consumption within the Intestinal Vasculature. In: Lübbers, D.W., Acker, H., Leniger-Follert, E., Goldstrick, T.K. (eds) Oxygen Transport to Tissue-V. Advances in Experimental Medicine and Biology, vol 169. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1188-1_48
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DOI: https://doi.org/10.1007/978-1-4684-1188-1_48
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