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Flow Dependence and Independence of Oxygen Consumption within the Intestinal Vasculature

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Oxygen Transport to Tissue-V

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 169))

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Abstract

The curve presenting the relation between oxygen consumption (V̇o2) and blood flow (BF) can be divided into two parts (see Fig. 1). The first one shows a proportionality between the values, supporting the hypothesis of a metabolic control of blood flow. In the second portion a distinct saturation of oxygen consumption is reached, A variation in O2 consumption is then possible independent of flow, thereby changing the amount of O2 extraction. In this upper range a metabolic control of blood flow becomes insufficient to explain changes in the horizontal course of the pressure-flow curve, generally called “autoregulation of blood flow” (see Fig. 3).

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References

  • Bartels, H., and Harms, H., 1959, Sauerstoffdissoziationskurven des Blutes von Säugetieren, Pflügers Arch. Ges. Physiol., 268: 334–365.

    Article  CAS  Google Scholar 

  • Granger, H.J., and Shepherd, A.P., 1979, Dynamics and control of the microcirculation, in: “Advances in Biomedical Engineering”, Vol. 7, J.H.V. Brown, ed., Academic Press, New York, pp. 1–63.

    Google Scholar 

  • Hamar, J., Ligeti, L., Kovach, A.G.B., Tkachenko, B.I., Ovsjannikov, V., and Tcherniavskaja, G.V., 1978, Blood supply and O2 consumption of the small intestine in low flow, Acta Physiol. Acad. Sci. Hung., 52: 351–390.

    Google Scholar 

  • Johnson, P.C., 1964, Origin, localisation and homeostatic significance of autoregulation in the intestine, Circ. Res., 15, Suppl. 1: 225–232.

    PubMed  CAS  Google Scholar 

  • Kvietys, P.R., and Granger, D.N., 1982, Relation between intestinal blood flow and oxygen uptake, Am. J. Physiol., 242: G202–208.

    PubMed  CAS  Google Scholar 

  • Lutz, J., 1966, fiber veno-vasomotorische Gefäßreaktionen im Mesen-terialkreislauf der Katze, Pflügers Arch. Ges. Physiol., 287: 330–344.

    Article  CAS  Google Scholar 

  • Lutz, J., 1969, Hämodynamisehe Eigenschaften und Gefäßreaktionen der intestinalen Strombahn, Arch. Kreislaufforsch., 59: 99–152.

    Article  PubMed  CAS  Google Scholar 

  • Lutz, J., Henrich, H., and Bauereisen, E., 1975, Oxygen supply and uptake in the liver and the intestine, Pflügers Arch., 360: 7–15.

    Article  PubMed  CAS  Google Scholar 

  • Mellander, S., and Johansson, B., 1968, Control of resistance, exchange and capacitance functions in the peripheral circulation, Pharmacol. Rev., 20: 117–196.

    PubMed  CAS  Google Scholar 

  • Öhman, V., 1976, Blood flow and oxygen consumption in the feline small intestine; responses to artificial distension and intestinal obstruction, Acta Chir. Scand., 142: 329–333.

    PubMed  Google Scholar 

  • Shepherd, A.P., 1982, Metabolic control of intestinal oxygenation and blood flow, Fed. Proc, 41: 2084–2089.

    PubMed  CAS  Google Scholar 

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© 1984 Plenum Press, New York

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Lutz, J. (1984). Flow Dependence and Independence of Oxygen Consumption within the Intestinal Vasculature. In: Lübbers, D.W., Acker, H., Leniger-Follert, E., Goldstrick, T.K. (eds) Oxygen Transport to Tissue-V. Advances in Experimental Medicine and Biology, vol 169. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1188-1_48

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  • DOI: https://doi.org/10.1007/978-1-4684-1188-1_48

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1190-4

  • Online ISBN: 978-1-4684-1188-1

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