A Comparison of the Methods for Assessment of Myocardial Capillarity
In all models of the O2 supply to the tissue, starting from the classical model of Krogh (1919), one of the principal input variables is the maximal diffusion distance, i.e. the longest distance from the capillary. This is equal in the Krogh model to the radius of the tissue cylinder. In most models, it is assumed that the maximal diffusion distance is equal to half of the inter-capillary distance.
KeywordsConcentric Circle Capillary Density Spontaneous Hypertension Point Counting Method Capillary Radius
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- Krogh, A., 1919, The number and distribution of capillaries in muscles with calculations of the oxygen pressure head necessary for supplying the tissue, J. Physiol. (Lond.), 52: 409.Google Scholar
- Loats, J.T., Sillau, A.H., and Banchero, N., 1978, How to quantify skeletal muscle capillarity, in: “Oxygen Transport to Tissue III”, I.A. Silver, M. Erecinska, H.I. Bicher, eds., Plenum Press, New York and London, p. 41.Google Scholar
- Rakusan, K., 1971, Quantitative morphology of capillaries of the heart, in: “Functional Morphology of the Heart”, E. Bajusz, G. Jasmin, eds., Karger, Basel, p. 272.Google Scholar
- Renkin, E.M., Gray, S.D., Dodd, L.R., and Lia, B.D., 1981, Heterogeneity of capillary distribution and capillary circulation in mammalian skeletal muscles, in: “Underwater Physiology VII”, A.J. Bachrach, M.M. Matzen, eds., Undersea Medical Soc, Bethesda.Google Scholar