Effects of Propranolol and Epinephrine on Capillary Plasma Filling and Minimal Intercapillary Distances in the Rat Heart

  • P. Vetterlein
  • G. Schmidt
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 169)


Many factors may influence substrate exchange between blood and tissue in the heart. One of these is variations in the density of the perfused capillaries (Honig and Gayeski, in press). In this study we examined the density of capillaries which are open to plasma flow at rest compared to decreased or increased cardiac work.


Capillary Density Fiber Density Muscular Fiber Cardiac Work Perfuse Capillary 
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  1. Bassingthwaighte, J.B., Yipintsoi, T., and Harvey, R.B., 1974, Microvasculature of the dog ventricular myocardium, Microvasc. Res., 7: 229.PubMedCrossRefGoogle Scholar
  2. Honig, C.R., and Gayeski, T.E.J., Capillary reserve and tissue O2 transport in normal and hypertrophied hearts, Basic Res. Cardiol., in press.Google Scholar
  3. Honig, C.R., and Gayeski, T.E.J., in press, Capillary reserve and tissue O2 transport in normal and hyertrophied hearts, NIH Symposium, Workshop on “Left Ventricular Hypertrophy”, Raven Press, New York.Google Scholar
  4. Hort, W., 1960, Makroskopische und micrometrische Untersuchungen am Myocard verschieden stark gefüllter linker Kammern, Virchows Arch, path, Anat., 33S: 523.Google Scholar
  5. Rakusan, K., 1971, Quantitative morphology of capillaries of the heart. Number of capillaries in animals and human hearts under normal and pathological conditions, in.: “Methodological Achievements of Experimental Pathology”, E. Bajusz and G. Jasmin, eds., Karger, Basel.Google Scholar
  6. Sonnenblick, E.H., and Skelton, C.L., 1974, Reconsideration of the ultrastructural basis of cardiac length-tension relations, Brief review, Circ. Res., 35: 517.PubMedCrossRefGoogle Scholar
  7. Vetterlein, F., dal Ri, H., and Schmidt, G., 1982, Capillary density in rat myocardium during time plasma staining, Am. J. Physiol., 242: H133.PubMedGoogle Scholar
  8. Wright, A.J.A., and Hudlicka, O., 1981, Capillary growth and changes in heart performance induced by chronic bradycardial pacing in the rabbit, Circ. Res., 49: 469.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • P. Vetterlein
    • 1
  • G. Schmidt
    • 1
  1. 1.Institut für Pharmakologie und ToxikologieGöttingenGermany

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