Glycolysis and Regulation of Cerebral Blood Flow and Metabolism

  • E. Dóra
  • A. G. B. Kovách
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 169)


In past decades several humoral agents and neural mechanisms were suggested for the coupling between cerebral blood flow (CBF), metabolism and functional activity in the brain (Siesjö, 1978). To explore the role of glycolysis in the regulation of CBF, and also to assess the importance of glucose as a substrate in the energy homeostasis of the brain, glycolysis was inhibited topically in the brain cortex by iodoacetate (IAA).


Cerebral Blood Flow Epileptic Seizure Brain Cortex NADH Oxidation Lingual Artery 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • E. Dóra
    • 1
  • A. G. B. Kovách
    • 1
  1. 1.Exp. Res. Dept. and 2nd Institute of PhysiologySemmelweis University Medical SchoolBudapestHungary

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