Abstract
The American Cancer Society began a review in 1978 of all data regarding the antimitotic effect of interferons, the effect of interferons on immuno-effector cells, the activity of interferons against animal tumors, and the results of preliminary clinical trials of interferons in the United States and Europe. At the conclusion of this review, a decision was made to initiate an interferon clinical trials program. Four tumor types were chosen for the initial clinical study: lymphomas, myeloma, melanoma and breast carcinoma.
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References
Balkwill, F., Watling, D., and Taylor-Papadimitriou, J. 1978, Inhibition by lymphoblastoid interferon of growth of cells derived from the human breast, Int. J. Cancer, 22:258.
Balkwill, F., Taylor-Papadimitriou, J., Fantes, K.H., and Sebesteny, A. 1980, Human lymphoblastoid interferon can inhibit the growth of human breast cancer xenografts in athymic (nude) mice. Eur. J. Cancer, 16:569.
Borden, E.C., and Ball, L.A. 1981, Interferons: biochemical, cell growth inhibitory, and immunological effects, Prog. Hematol., 12:299.
Borden, E.C., Gutterman, J.U., Holland, J.F., and Dao, T.L. 1981, Interferons in breast carcinoma: design and background leading to the American Cancer Society Program, in: “The Biology of the Interferon System”, pp.391, E. DeMaeyer, G. Galasso, and H. Schellekens, eds., Elsevier/North Holland Biomedical Press, Amsterdam.
Borden, E.C., Holland, J.F., Dao, T.L., Gutterman, J.U., Wiener, L., Chang, Y-C., and Patel, J. 1982, Leukocyte-derived interferon (a) in human breast carcinoma, Ann. Int. Med., 97:1.
Came, P.E., and Moore, D.H. 1972, Effect of exogenous interferon treatment on mouse mammary tumors, J. Natl. Cancer Inst., 48:1151.
Cantell, K., Hirvonen, S., Morensen, K.E., and Phyälä, L. 1973, Human leukocyte interferon: production, purification, stability and animal experiments in the production and use of interferon for the treatment and prevention of human virus infection, in: “Proceedings of a Tissue Culture Association Workshop”, C. Waymouth, ed., In vitro Monography, 3:35.
Chirigos, M.A., and Pearson, J.W. 1973, Cure of murine leukemia with drug and interferon treatment, J. Natl. Cancer Inst., 51:1367.
Gresser, I. 1977, On the varied biologic effect of interferon, Cellular Immunol., 34:406.
Gresser, I., Maury, C., and Tovey, M. 1978, Efficacy of combined interferon cyclophosphamide therapy after diagnosis of lymphoma in AKR mice, Eur. J. Cancer, 14:97.
Gutterman, J.U., Blumenschein, G.R., Alexanian, R., Yap, H-Y., Buzdar, A.U., Cabanillas, F., Hortobagyi, G.N., Hersh, E.M., Rasmussen, S.L., Harmon, M., Kramer, M., and Pestka, S. 1980, Leukocyte interferon-induced tumor regression in human metastatic breast cancer, multiple myeloma, and malignant lymphoma, Ann. Int. Med., 93:399.
Ortaldo, J.R., and McCoy, J.L. 1980, Protective effects of interferon in mice previously exposed to lethal irradiation, Rad. Res., 81:262.
Strander, H., Adamson, V., Aparisi, T., Broström, L.A., Cantell, K., Einhorn, S., Hall, K., Ingimarsson, S., Nilsonne, U., and Söderberg, G. 1978, Adjuvant interferon treatment of osteosarcoma, Recent Results Cancer Res., 68:40.
Vilcek, J., Gresser, L., and Merigan, T. 1980, Regulatory functions of interferons, Annals NY Acad. Sei., 350:1.
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© 1983 Plenum Press, New York
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Borden, E.C., Gutterman, J.U., Holland, J.F., Dao, T.L. (1983). Breast Cancer. In: Sikora, K. (eds) Interferon and Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1170-6_10
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DOI: https://doi.org/10.1007/978-1-4684-1170-6_10
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