Abstract
It is now well established that the central nervous system (CNS) exercises control over the secretion of the adenohypophyseal hormones through releasing factors synthesized and secreted by peptidergic neurons in the hypothalamus (Blackwell and Guillemin, 1973; Reichlin et al., 1976). According to the “portal vessel chemotransmitter hypothesis,” first clearly articulated by Harris (1948), specific hypophysiotropic factors are secreted into the portal capillaries of the median eminence and from there transported to the anterior pituitary by the portal vessels of the pituitary stalk (Fig. 1).
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Jackson, I.M.D., Mueller, G.P. (1982). Neuroendocrine Interrelationships. In: Goldberger, R.F., Yamamoto, K.R. (eds) Biological Regulation and Development. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1125-6_4
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