Abstract
Three single-stranded RNA viruses cause childhood diseases for which vaccines are available. Measles and mumps are paramyxoviruses, and rubella is a togavirus. These viruses range in size from 50 to 270 nm and all have lipid coats with multiple surface projections containing a hemagglutinin and, in the case of mumps, a neuraminidase. They all undergo cytoplasmic replication with budding and are similarly “fragile” viruses. However, each is unique in its own way. These similarities and differences will be noted in this chapter, with a concentration on characteristics of host-virus interactions that explain human disease processes.
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References
Measles
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Mumps
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Frenkel, L.D., Bellanti, J.A. (1982). Immunology of Measles, Mumps, and Rubella Viruses. In: Nahmias, A.J., O’Reilly, R.J. (eds) Immunology of Human Infection. Comprehensive Immunology, vol 9. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1012-9_6
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