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Immunology of Human Infection pp 441–474Cite as

Immunology of Chlamydial Infections

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Part of the book series: Comprehensive Immunology ((COMIMUN,volume 8))

Abstract

With its long recorded history, its high global prevalence, and its potential for causing partial or total blindness, trachoma ranks as one of the major afflictions of humanity (Bietti, 1974; Jones, 1975; Locatcher-Khorazo and Seegal, 1972; Nataf, 1952; Thygeson, 1971). The principal etiological agent of trachoma is an intracellular parasitic prokaryote, currently assigned to the genus Chlamydia (Becker, 1974, 1978; Moulder, 1964, 1966; Page, 1968; Storz, 1971; E. Weiss, 1971). The species designation of the trachoma organism is C. trachomatis (Page, 1968). Various serotypes of C. trachomatis also cause, besides trachoma-inclusion conjunctivitis (TRIC), some cases of nongonococcal Urethritis and Cervicitis (Dunlop, 1975; Fritsch et al., 1910; Hobson and Holmes, 1977; Jones et al., 1964; Lindner, 1910; Oriel et al., 1978; Richmond and Sparling, 1976; Schachter et al., 1976), some cases of infant pneumonia (Beem and Saxon, 1977; Frommell et al., 1977; Schachter et al., 1975), and lymphogranuloma venereum (LGV) (Abrams, 1968; Meyer, 1953; Rake and Jones, 1942; Willcox, 1975). Organisms assigned to the species C. psittaci are distinguished by their failure to store glycogen during growth (Becker, 1978; Gordon and Quan, 1965; Jenkin and Fan, 1971): divers strains cause ornithosis (Bedson, 1958) and various diseases in nonhuman mammals, such as pneumonia, encephalitis, conjunctivitis, enteritis, abortion, and polyarthritis (Storz, 1971).

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  1. Hayes C. Lamont

    Present address: Department of Biology, Suffolk University, Boston, Massachusetts, 02114, USA

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    Hayes C. Lamont & Roger L. Nichols

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    André J. Nahmias

  2. Memorial Sloan-Kettering Cancer Center, New York, New York, USA

    Richard J. O’Reilly

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Lamont, H.C., Nichols, R.L. (1981). Immunology of Chlamydial Infections. In: Nahmias, A.J., O’Reilly, R.J. (eds) Immunology of Human Infection. Comprehensive Immunology, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1009-9_18

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