Abstract
The IgG concentration in the cerebrospinal fluid (CSF) is commonly expressed as a percentage of the protein concentration, because the condition of the blood-CSF barrier must be taken into account. Another method of expressing IgG-CSF results is the calculation of albumin and IgG ratio’s (CSF concentration/ serum concentration), in which not only the permeability of the blood-CSF barrier but also the IgG concentration in the serum is taken into consideration (1). In a disease in which IgG-CSF elevations are found frequently (multiple sclerosis), it is important to establish the clinical value of this increase.
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References
Ganrot, K., Laurell, G.B.: Measurement of IgG and albumin content of cerebrospinal fluid, and its interpretation. Clin. Chem. 20: 571–573, 1974
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© 1979 Plenum Press, New York
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van Walbeek, H.K., van der Helm, H.J. (1979). The Clinical Significance of Immunoglobulin G (IgG) Determinations in the CSF of Multiple Sclerosis Patients. In: Karcher, D., Lowenthal, A., Strosberg, A.D. (eds) Humoral Immunity in Neurological Diseases. NATO ASI Series, vol 24. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1003-7_30
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DOI: https://doi.org/10.1007/978-1-4684-1003-7_30
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-1005-1
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