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Study of Oligoclonal C.S.F. by New Immunofixation Techniques following Electrophoresis on Cellulose Acetate Gel

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Humoral Immunity in Neurological Diseases

Part of the book series: NATO ASI Series ((NSSA,volume 24))

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Abstract

Oligoclonal bands are usually revealed by electrophoresis on agar gel (l) or on cellulose acetate strip (2). We have used a particular cellogel, the Cellogel RS (Sebia Lab.) to explore the CSF of patients with multiple sclerosis (MS) (3). The oligoclonal patterns show several fine and close bands in the cathodic part of the electropherogram. We report here an electroimmunofixation technique to study the antigenic determinants of the gammaglobulinic bands. We describe briefly the method and more details will be published further.

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© 1979 Plenum Press, New York

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Perini, J.M., Lebas, J., Roussel, P., Biserte, G. (1979). Study of Oligoclonal C.S.F. by New Immunofixation Techniques following Electrophoresis on Cellulose Acetate Gel. In: Karcher, D., Lowenthal, A., Strosberg, A.D. (eds) Humoral Immunity in Neurological Diseases. NATO ASI Series, vol 24. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1003-7_25

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  • DOI: https://doi.org/10.1007/978-1-4684-1003-7_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1005-1

  • Online ISBN: 978-1-4684-1003-7

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