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Cellular, Molecular, and Clinical Aspects of Allergic Disorders pp 139–151Cite as

Molecular Properties of Allergens

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Part of the book series: Comprehensive Immunology ((COMIMUN,volume 6))

Abstract

A wide variety of natural or synthetic substances which are foreign to the host can act as antigens or immunogens to induce immunological responses in man and animals. Most immunological responses are beneficial for the host, but some are not. The immunological responses harmful to the host are called “hypersensitivity” or “allergy.” Allergic responses are classified into two types, immediate and delayed, on the basis of the lag in their appearance following challenge with allergen. The immediate type is mediated by specific antibodies of different immunoglobulin classes, while the delayed type is mediated by specifically acti­vated T lymphocytes. The immediate type is further divided into those mediated by antibodies of the IgE class and those mediated by antibodies of Ig classes other than IgE; the IgE-mediated allergy is also known as “atopy.” The chemical nature of the cellular component of T lymphocytes responsible for delayed-type allergy is as yet unknown.

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Authors and Affiliations

  1. The Rockefeller University, New York, New York, 10021, USA

    T. P. King

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  1. T. P. King
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Editors and Affiliations

  1. Sloan-Kettering Institute for Cancer Research, New York, New York, USA

    Sudhir Gupta M.D., F.R.C.P.(C), F.A.C.P.  & Robert A. Good Ph.D., M.D.  & 

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© 1979 Plenum Publishing Corporation

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King, T.P. (1979). Molecular Properties of Allergens. In: Gupta, S., Good, R.A. (eds) Cellular, Molecular, and Clinical Aspects of Allergic Disorders. Comprehensive Immunology, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0988-8_4

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  • DOI: https://doi.org/10.1007/978-1-4684-0988-8_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0990-1

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