Abstract
Several important discoveries of the past few decades have launched a renaissance of research into basophil and mast cell function. These include the discovery of IgE and its affinity for basophils and mast cells and the demonstration of the ability of these cells to elaborate and release not only histamine but also a variety of lowmolecular-weight mediators of immediate hypersensitivity. Moreover, the application of modern methods of tissue fixation and processing has permitted confident identification of basophils and mast cells with both the light and electron microscopes in diverse experimental and clinical situations, and has clearly implicated these cells in a variety of delayed-onset immunological phenomena where their participation had been entirely unexpected.
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Åborg, C.-H., and Uvnäs, B., 1968, Mode of binding of histamine and some other biogenic amines to a protamine-heparin complex in vitro, Acta Physiol. Scand. 74: 552–567.
Ackerman, G. A., 1963, Cytochemical properties of the blood basophilic granulocytes, Ann. N.Y. Acad Sci. 103: 376–393.
Ackerman, G. A., and Bellios, N.C., 1955, A study of the morphology of the living cells of blood and bone marrow in vital films with the phase microscope. I. Normal blood and bone marrow, Blood 10: 3–16.
Ackerman, G. A., and Clark, M. A., 1971, Ultrastructural localization of peroxidase activity in human basophil leukocytes, Acta Haematol. 45: 280–284.
Allen, A. M., 1962, Deoxyribonucleic acid synthesis and mitosis in mast cells of the rat, Lab. Invest. 11: 188–191.
Allen, J. R., 1973, Tick resistance: Basophils in skin reactions of resistant guinea pigs, Int. J. Parasitol. 3: 195–200.
Amann, R., and Martin, H., 1961, Blutmastzellen and Heparin, Acta Haematol. 25: 209–219.
Anderson, P., and Uvnäs, B., 1975, Selective localization of histamine to electron dense granules in antigen-challenged sensitized rat mast cells and to similar granules isolated from sonicated mast cells. An electron microscope autoradiographic study, Acta Physiol. Scand. 94: 63–73.
Anderson, P., Slorach, S. A., and Uvnäs, B., 1973, Sequential exocytosis of storage granules during antigen-induced histamine release from sensitized mast cells in vitro. An electron microscopic study, Acta Physiol. Scand. 88: 359–372.
Archer, G. T., and Jackas, M., 1965, Disruption of mast cells by a component of eosinophil granules, Nature (London) 205: 599–600.
Askenase, P. W., 1973, Cutaneous basophil hypersensitivity in contact-sensitized guinea pigs. I. Transfer with immune serum, J. Exp. Med. 138: 1144–1155.
Askenase, P. W., 1976, Cutaneous basophil hypersensitivity uncovered in the cell transfer of classical tuberculin hypersensitivity, J. Immunol. 117: 741–747.
Askenase, P. W., 1977, The role of basophils, mast cells and vasoamines in hypersensitivity reactions with a delayed time course, Prog. Allergy 23: 199–320.
Askenase, P. W., and Atwood, J. E., 1976, Basophils in tuberculin and “Jones-Mote” delayed reactions of humans, J. Clin. Invest. 58: 1145–1154.
Askenase, P. W., Hayden, B., and Higashi, G., 1975a, Cutaneous basophil hypersensitivity (CBH) and macrophage migration inhibition (MMI) in guinea pigs with schistosomiasis, J. Allergy Clin. Immunol. 55: 111.
Askenase, P. W., Haynes, J. D., Tauben, D., and DeBernardo, R., 1975b, Specific basophil hypersensitivity induced by skin testing and transferred using immune serum, Nature (London) 256: 52–54.
Askenase, P. W., Haynes, J. D., and Hayden, B. J., 1976, Antibody-mediated basophil accumulations in cutaneous hypersensitivity reactions in guinea pigs, J. Immunol. 117: 1722–1730.
Askenase, P. W., Hayden, B., and Gershon, R. K., 1977, Evanescent delayed-type hypersensitivity: Mediation by effector cells with a short life span, J. Immunol. 119: 1830–1835.
Askenase, P. W., Boone, W. T., and Binder, H. J., 1978a, Colonic basophil hypersensitivity, J. Immunol. 120: 198–201.
Askenase, P. W., DeBernardo, R., Tauben, D., and Kashgarian, M., 1978b, Cutaneous basophil anaphylaxis. Immediate vasopermeability increases and anaphylactic degranulation of basophils at delayed hypersensitivity reactions challenged with additional antigen, Immunology 35: 741–755.
Assem, E. S. K., 1974, Leukocyte-bound IgE and cell reactivity in asthma, Allerg. Immunopathol. 2: 41–46.
Assem, E. S. K., and Richter, A. W., 1971, Comparison of in vivo and in vitro inhibition of the anaphylactic mechanism by /3-adrenergic stimulants and disodium cromoglycate, Immunology 21: 729–739.
Atkins, P., Green, G. R., and Zweiman, B., 1973, Histologic studies of human eosinophil and mast cell responses to ragweed, compound 48/80 and histamine, J. Allergy Clin. Immunol. 51: 263–273.
Austen, K. F., and Becker, E. L., 1966, Mechanisms of immunologic injury of rat peritoneal mast cells. II. Complement requirement and phosphonate ester inhibition of release of histamine by rabbit anti-rat gamma globulin, J. Exp. Med. 124: 397–419.
Austen, K. F., and Brocklehurst, W. E., 1961, Anaphylaxis in chopped guinea pig lung. I. Effect of peptidase substrates and inhibitors, J. Exp. Med. 113: 521–539.
Austen, K. F., and Humphrey, J. H., 1961, Release of histamine from rat peritoneal mast cells by antibody against rat y-globulin, J. Physiol. (London) 158: 36P - 37 P.
Austen, K. F., Lewis, R. A., Stechschulte, D. J., Wasserman, S. I., Leid, R. W., Jr., and Goetzl, E. J., 1974, Generation and release of chemical mediators of immediate hypersensitivity, in: Progress in Immunology II, Vol. 2 ( L. Brent and J. Holborow, eds.), pp. 61–71, North-Holland, Amsterdam.
Bach, M. K., and Brashler, J. R., 1975, Inhibition of IgE and compound 48/80 induced histamine release by lectins, Immunology 29: 371–386.
Bach, M. K., Bloch, K. J., and Austen, K. F., 1971a, IgE and IgGa antibody-mediated release of histamine from rat peritoneal cells. II. Interaction of IgGa and IgE at the target cells, J. Exp. Med. 133: 772–784.
Bach, M. K., Brashler, J. R., Bloch, K. J., and Austen, K. F., 1971b, Studies on the receptor site for IgE antibody on the peritoneal mast cell of the rat, in: Biochemistry of the Acute Allergic Reactions ( K. F. Austen and E. L. Becker, eds.), pp. 65–89, Blackwell, Oxford.
Bach, M. K., Bach, S., Brashler, J. R., Ishizaka, T., and Ishizaka, K., 1978, On the nature of the presumed receptor for IgE on mast cells. V. Enhanced binding of 125I labeled IgE to cell-free particulate fractions in the presence of protease inhibitors, Int. Arch. Allergy Appl. Immunol. 56: 1–13.
Bagnall, B. G., 1975, Cutaneous immunity to the tick Ixodes holocyclus, thesis, University of Sydney, Australia, as cited by Askenase, 1977.
Barnett, M. L., 1973, Mast cells in the epithelial layer of human gingiva, J. Ultrastruct. Res. 43: 247–255.
Baxter, J. H., and Adamik, R., 1975, Control of histamine release: Effect of various conditions on rate of release and rate of cell sensitization, J. Immunol. 114: 1034–1041.
Becker, E. L., and Austen, K. F., 1964, A comparison of the specificity of inhibition by phosphonate esters of the first component of complement and the antigen-induced release of histamine from guinea pig lung, J. Exp. Med. 120: 491–506.
Becker, E. L., and Austen, K. F., 1966, Mechanisms of immunologic injury of rat peritoneal mast cells. I. The effects of phosphonate inhibitors on the homocytotropic antibody-mediated histamine release and the first component of rat complement, J. Exp. Med. 124: 379–395.
Becker, E. L., and Henson, P. M., 1973, In vitro studies of immunologically induced secretion of mediators from cells and related phenomena, Adv. Immunol. 17: 93–193.
Becker, K. E., Ishizaka, T., Metzger, H., Ishizaka, K., and Grimely, P. M., 1973, Surface IgE in human basophils during histamine release, J. Exp. Med. 138: 394–409.
Behrendt, H., Rosenkranz, U., and Schmutzler, W., 1978, Ultrastructure of isolated human mast cells during histamine release induced by ionophore A23187, Int. Arch. Allergy Appl. Immunol. 56: 188–192.
Bennich, H., and Johansson, S. G. O., 1967, Studies on a new class of human immunoglobulins II Chemical and physical properties, in: Nobel Symposium 3. Gamma Globulin, Structure and Control of Biosynthesis ( J. Killander, ed.), p. 199, Almqvist and Wiksell, Stockholm.
Bennich, H., Ishizaka, K., Ishizaka, T., and Johansson, S. G. O., 1%9, A comparative antigenic study of yE-globulin and myeloma-IgND, J. Immunol. 102: 826–831.
Benveniste, J., Henson, P. M., and Cochrane, C. G., 1973, A possible role for IgE in immune complex disease, in: The Biological Role of the Immunoglobulin E System ( K. Ishizaka and D. H., Dayton, eds.), pp. 187–205, U. S. Government Printing Office, Washington.
Bernstein, I. L., Vijay, H. M., and Perelmutter, L., 1977, Non-responder basophils in highly ragweed-sensitive subjects, Int. Arch. Allergy Appl. Immunol. 55: 215–216.
Blenkinsopp, W. K., 1967, Mast cell proliferation in adult rats, J. Cell Sci. 2: 33–37.
Boetcher, D. A., and Leonard, E. J., 1973, Basophil chemotaxis: Augmentation by a factor from stimulated lymphocyte cultures, Immunol. Commun. 2: 421–429.
Bourne, H. R., Melmon, K. L., and Lichtenstein, L. M., 1971, Histamine augments leukocyte cyclic AMP and blocks antigenic histamine release, Science 173: 743–745.
Bourne, H. R., Lichtenstein, L. M., and Melmon, K. L., 1972, Pharmacologic control of allergic histamine release in vitro: Evidence for an inhibitory role of 3’,5’-adenosine monophosphate in human leukocytes, J. Immunol. 108: 695–705.
Bourne, H. R., Lichtenstein, L. M., Melmon, K. L., Henney, C. S., Weinstein, Y., and Shearer, G. M., 1974, Modulation of inflammation and immunity by cyclic AMP, Science 184: 19–28.
Braunsteiner, H., 1962, Mast cells and basophilic leukocytes, in: The Physiology and Pathology of Leukocytes (H. Braunsteiner and D. Zucker-Franklin, eds.), Ch. 2, Grune and Stratton, New York.
Brinkman, G. L., 1968, The mast cell in normal human bronchus and lung, J. Ultrastruct. Res. 23: 115–123.
Brittinger, G., Hirschhorn, R., Douglas, S. D., and Weissmann, G., 1968, Studies on lysosomes. XI.
Characterization of a hydrolase-rich fraction from human lymphocytes, J. Cell Biol. 37:394–411. Bruce, C. A., Rosenthal, R. R., Lichtenstein, L. M., and Norman, P. S., 1974, Diagnostic tests in ragweed-allergic asthma, J. Allergy Clin. Immunol. 53: 230–239.
Buonassisi, V., and Root, M., 1975, Enzymatic degradation of heparin-related mucopolysaccharides from the surface of endothelial cell cultures, Biochim. Biophys. Acta 385: 1–10.
Bursztajn, S., Askenase, P. W., Gershon, R. K., and Gershon, M. D., 1978, Role of vasoactive amines during early stages of delayed-type hypersensitivity skin reactions, Fed. Proc. 37: 590.
Burton, A. L., and Higginbotham, R. D., 1966, Response of blood basophils to Rous sarcoma virus infection in chicks and its significance, J. Reticuloendothel. Soc. 3: 314–326.
Chakravarty, N., 1968, Respiration of rat peritoneal mast cells during histamine release induced by antigen-antibody reaction, Exp. Cell Res. 49: 160–168.
Chan, B. S. T., 1972, Ultrastructural changes in guinea-pig bone marrow basophils during anaphylaxis, Immunology 23: 215–224.
Charkin, L. W., Krell, R. D., Mengel, J., Young, D., Zaher, C., and Wardell, J. R., 1974, Effect of -a histamine H2-receptor antagonist on immunologically induced mediator release in vitro. Agents Actions 4: 297–303.
Clark, J. M., and Higginbotham, R. D., 1968, Significance of the mast cell response to a lysosomal protein, J. Immunol. 101: 488–499.
Clark, J. M., Altman, G., and Fromowitz, F. B., 1976, Basophil hypersensitivity response in rabbits, Infect. Immunun. 15: 305–312.
Clark, R. A. F., Gallin, J. I., and Kaplan, A. P., 1975, The selective eosinophil chemotactic activity of histamine, J. Exp. Med. 142: 1462–1476.
Clark, R. A. F., Sandler, J. A., Gallin, J. I., and Kaplan, A. P., 1977, Histamine modulation of eosinophil migration, J. Immunol. 118: 137–145.
Cochrane, C. G., 1971, Mechanisms involved in the deposition of immune complexes in tissues, J. Exp. Med. 134: 75S - 89S.
Cochrane, C. G., and Koffler, D., 1973, Immune complex disease in experimental animals and man, Adv. Immunol. 16: 185–264.
Cochrane, C. G., and Müller-Eberhard, H. J., 1968, The derivation of two distinct anaphylatoxin activities from the third and fifth components of human complement, J. Exp. Med. 127: 371–386.
Coffey, R. G., and Middleton, E., Jr., 1973, Release of histamine from rat mast cells by lysosomal cationic proteins, Int. Arch. Allergy Appl. Immunol. 45: 593–611.
Cohn, Z. A., and Parks, E., 1967, The regulation of pinocytosis in mouse macrophages. II. Factors inducing vesicle formation, J. Exp. Med. 125: 213–232.
Colvin, R. B., and Dvorak, H. F., 1974, Basophils and mast cells in renal allograft rejection, Lancet 1: 212–214.
Colvin, R. B., and Dvorak, H. F., 1975, Role of the clotting system in cell-mediated hypersensitivity. II. Kinetics of fibrinogen/fibrin accumulation and vascular permeability. Changes in tuberculin and cutaneous basophil hypersensitivity reactions, J. Immunol. 114: 377–387.
Colvin, R. B., Johnson, R. A., Mihm, M. C., Jr., and Dvorak, H. F., 1973a, Role of the clotting system in cell-mediated hypersensitivity. I. Fibrin deposition in delayed skin reactions in man, J. Exp. Med. 138: 686–698.
Colvin, R. B., Pinn, V. W., Simpson, B. A., and Dvorak, H. F., 1973b, Cutaneous basophil hypersensitivity. IV. The “late reaction”: Sequel to Jones-Mote type hypersensitivity. Comparison with rabbit Arthus reaction. Effect of passive antibody on induration and expression of Jones-Mote hypersensitivity, J. Immunol. 110: 1279–1289.
Colvin, R. B., Dvorak, A. M., and Dvorak, H. F., 1974, Mast cells in the cortical tubular epithelium and interstitium in human renal disease, Hum. Pathol. 5: 315–326.
Conrad, D. H., Bazin, H., Sehon, A. H., and Froese, A., 1975, Binding parameters of the interaction between rat IgE and rat mast cell receptors, J. Immunol. 114: 1688–1691.
Conroy, M. C., Adkinson, N. F., Jr., and Lichtenstein, L. M., 1977, Measurement of IgE on human basophils: Relation to serum IgE and anti-IgE-induced histamine release, J. Immunol. 118: 1317–1321.
Crowle, A. J., 1975, Delayed hypersensitivity in the mouse, Adv. Immunol. 20: 197–264.
Csaba, G., Hodinka, L., and Surjân, L., Jr., 1969, Transport of mast cells by the blood circulation, Experientia 25: 735–736.
Day, R. P., Dolovich, J., and Bienenstock, J., 1974, Characteristics of tritiated histamine uptake and release by human basophils, Fed. Proc. 33: 752.
DeBernardo, R., Askenase, P., Tauben, D., and Douglas, J., 1975, Augmented anaphylaxis at sites of cutaneous basophil hypersensitivity, J. Allergy Clin. Immunol. 55: 112.
DeChatelet, L. R., McCall, C. E., and Cooper, M. R., 1972, Inhibition of leukocyte acid phosphatase by heparin, Clin. Chem. 18: 1532–1534.
DeMeyts, P., 1976, Cooperative properties of hormone receptors in cell membranes, in: Proceedings of the 1975 ICN-UCLA Winter Conference on Cell and Molecular Biology, J. Supramol. Struct. 4: 241–258.
de Shazo, R. D., Levinson, A. I., Dvorak, H. F., and Davis, R. W., 1979, The late phase skin reaction: Evidence for activation of the coagulation system in an IgE-dependent reaction in man, J. Immunol. 122: 692–698.
Dineen, J., 1978, The role of homocytotropic antibodies in immunity and pathology of helminthiasis with special reference to the induction and potentiation of IgE production, in: Immediate Hypersensitivity: Modern Concepts and Developments ( M. K. Bach, ed.), pp. 211–257, Dekker, New York.
Dolovich, J., Hargreave, F. E., Chalmers, R., Sheir, K. J., Gauldie, J., and Bienenstock, J., 1973, Late cutaneous allergic responses in isolated IgE-dependent reactions, J. Allergy Clin. Immunol. 52: 33–46.
Dorrington, K. J., and Bennich, H. H., 1978, Physicochemical and conformational properties of immunoglobulin E, in: Immediate Hypersensitivity: Modern Concepts and Developments ( M. K. Bach, ed.), pp. 47–71, Dekker, New York.
Drobis, J. D., and Siraganian, R. P., 1976, Histamine release from cultured human basophils: Lack of histamine resynthesis after antigenic release, J. Immunol. 117: 1049–1053.
Dvorak, A. M., 1978, Biology and morphology of basophilic leukocytes, in: Immediate Hypersensitivity: Modern Concepts and Developments ( M. K. Bach, ed.), pp. 369–405, Dekker, New York.
Dvorak, A. M., Bast, R. C., Jr., and Dvorak, H. F., 1971, Morphologic changes in draining lymph nodes and in lymphocyte cultures after sensitization with complete or incomplete Freund’s adjuvant. Correlation with immunologic events in vivo and in culture, J. Immunol. 107: 422–435.
Dvorak, A. M., Dvorak, H. F., and Karnovsky, M. J., 1972, Uptake of horseradish peroxidase by guinea pig basophilic leukocytes, Lab. Invest. 26: 27–39.
Dvorak, A. M., Dickersin, G. R., Connell, A., Carey, R. W., and Dvorak, H. F., 1976a, Degranulation mechanisms in human leukemic basophils, Clin. Immunol. Immunopathol. 5: 235–246.
Dvorak, A. M., Mihm, M. C., Jr., and Dvorak, H. F., 1976b, Degranulation of basophilic leukocytes in allergic contact dermatitis reactions in man, J. Immunol. 116: 687–695.
Dvorak, A. M., Mihm, M. C., Jr., and Dvorak, H. F., 1976c, Morphology of delayed-type hypersensitivity reactions in man. II. Ultrastructural alterations affecting the microvasculature and the tissue mast cells, Lab. Invest. 34: 179–191.
Dvorak, H. F., 1971, Role of the basophilic leukocyte in allograft rejection, J. Immunol. 106:279–281. Dvorak, H. F., and Dvorak, A. M., 1972, Basophils, mast cells, and cellular immunity in animals and man, Hum. Pathol. 3: 454–456.
Dvorak, H. F., and Dvorak, A. M., 1974, Cutaneous basophil hypersensitivity, in: Progress in Immunology II, Vol. 3 ( L. Brent and J. Holborow, eds.), pp. 171–181, North-Holland, Amsterdam.
Dvorak, H. F., and Hammond, M. E., 1978, Cutaneous basophil hypersensitivity, in: Immediate Hypersensitivity: Modern Concepts and Developments ( M. K. Bach, ed.), pp. 659–692, Dekker, New York.
Dvorak, H. F., and Hirsch, M. S., 1971, Role of basophilic leukocytes in cellular immunity to vaccinia virus infection, J. Immunol. 107: 1576–1582.
Dvorak, H. F., and Mihm, M. C., Jr., 1972, Basophilic leukocytes in allergic contact dermatitis, J. Exp. Med. 135: 235–254.
Dvorak, H. F., Dvorak, A. M., Simpson, B. A., Richerson, H. B., Leskowitz, S., and Karnovsky, M. J., 1970, Cutaneous basophil hypersensitivity. II. A light and electron microscopic description, J. Exp. Med. 132: 558–582.
Dvorak, H. F., Simpson, B. A., Bast, R. C., Jr., and Leskowitz, S., 1971, Cutaneous basophil hypersensitivity. III. Participation of the basophil in hypersensitivity to antigen—antibody complexes, delayed hypersensitivity and contact allergy. Passive transfer, J. Immunol. 107: 138–148.
Dvorak, H. F., Dvorak, A. M., and Churchill, W. H., 1973, Immunologic rejection of diethylnitrosamine induced hepatomas in strain 2 guinea pigs: Participation of basophilic leukocytes and macrophage aggregates, J. Exp. Med. 137: 751–775.
Dvorak, H. F., Mihm, M. C., Jr., Dvorak, A. M., Johnson, R. A., Manseau, E. J., Morgan, E., and Colvin, R. B., 1974a, Morphology of delayed-type hypersensitivity reactions in man. I. Quantitative description of the inflammatory response. Lab. Invest. 31: 111–130.
Dvorak, H. F., Selvaggio, S. S., Dvorak, A. M., Colvin, R. B., Lean, D. B., and Rypysc, J., 1974b, Purification of basophilic leukocytes from guinea pig blood and bone marrow, J. Immunol. 113: 1694–1702.
Dvorak, H. F., Colvin, R. B., and Churchill, W. H., 1975, Specificity of basophils and lymphocytes in cutaneous basophil hypersensitivity, J. Immunol. 114: 507–511.
Dvorak, H. F., Mihm, M. C., Jr., and Dvorak, A. M., 1976, Morphology of delayed-type hypersensitivity reactions in man, J. Invest. Dermatol. 67: 391–401.
Dvorak, H. F., Hammond, M. E., Colvin, R. B., Manseau, E. J., and Goodwin, J., 1977a, Systemic expression of cutaneous basophil hypersensitivity, J. Immunol. 118: 1549–1557.
Dvorak, H. F., Orenstein, N. S., Dvorak, A. M., Hammond, M. E., Roblin, R. O., Feder, J., Schott, C. F., Goodwin, J., and Morgan, E., 1977b, Isolation of the cytoplasmic granules of guinea pig basophilic leukocytes: Identification of esterase and protease activities, J. Immunol. 119: 38–46.
Dvorak, H. F., Mihm, M. C., Jr., Dvorak, A. M., and Barnes, B. A., 1977c, First set skin allograft rejection in man, Fed. Proc. 36: 1071.
Dvorak, H. F., Orenstein, N. S., Rypysc, J., Colvin, R. B., and Dvorak, A. M., 1978, Plasminogen activator of guinea pig basophilic leukocytes: Probable localization to the plasma membrane, J. Immunol. 120: 766–773.
Ehrich, W. E., 1953, Histamine in mast cells, Science 118: 603.
Engvall, E., and Ruoslahti, E., 1977, Binding of soluble form of fibroblast surface protein, fibronectin, to collagen, Int. J. Cancer 20: 1–5.
Fawcett, D. W., 1955, An experimental study of mast cell degranulation and regeneration, Anat. Rec. 121: 29–52.
Feltkamp-Vroom, T. M., Stallman, P. J., Aalberse, R. C., and Reerink-Brongers, E. E., 1975, Immunofluorescence studies on renal tissue, tonsils, adenoids, nasal polyps, and skin of atopic and non-atopic patients with special reference to IgE, Clin. Immunol. Immunopathol. 4: 392–404.
Ferrarini, M., Munro, A., and Wilson, A. B., 1973, Cytophilic antibody: Correlation of its distribution with activation of basophils and macrophages, Eur. J. Immunol. 3: 364–370.
Foreman, J. C., and Mongar, J. L., 1975, Calcium and the control of histamine secretion from mast cells, in: Calcium Transport in Contraction and Secretion ( E. Carafoli, ed.), p. 175, North-Holland, Amsterdam.
Foreman, J. C., Mongar, J. L., and Gomperts, B. D., 1973, Calcium ionophores and movement of calcium ions following the physiological stimulus to a secretory process, Nature (London), 245: 249–251.
Foreman, J. C., Mongar, J. L., Gomperts, B. D., and Garland, L. G., 1975, A possible role for cyclic AMP in the regulation of histamine secretion and the action of cromoglycate, Biochem. Pharmacol. 24: 538–540.
Foreman, J. C., Garland, L. G., and Mongar, J. L., 1976, The role of Cat+ in secretory process-model studies in mast cells, in: Calcium in Biological Systems ( C. J. Duncan, ed.), Cambridge University Press, Cambridge.
Friedlaender, M. H., and Dvorak, H. F., 1977, Morphology of delayed-type hypersensitivity reactions in the guinea pig cornea, J. Immunol. 118: 1558–1563.
Galli, S. J., and Dvorak, H. F., 1975, Histamine synthesis by guinea pig basophils in short term tissue culture, Fed. Proc. 34: 1045.
Galli, S. J., Galli, A. S., Dvorak, A. M., and Dvorak, H. F., 1976, Metabolic studies of guinea pig basophilic leukocytes in short-term tissue culture. I. Measurement of histamine-synthesizing capacity by using an isotopic-thin layer chromatographic assay, J. Immunol. 117: 1085–1092.
Galli, S. J., Colvin, R. B., Verderber, E., Galli, A. S., Monahan, R., Dvorak, A. M., and Dvorak, H. F., 1978, Preparation of a rabbit anti-guinea pig basophil serum: in vitro and in vivo characterization, J. Immunol. 121: 1157–1166.
Galli, S. J., Orenstein, N. S., Gill, P. J., Silbert, J. E., Dvorak, A. M., and Dvorak, H. F., 1979, Sulfated glycosaminoglycans synthesised by basophil-enriched human leukaemic granulocytes in vitro, in: The Mast Cell, Proceedings of the Conference Held in Davos, Switzerland, April, 1979, Pitman Medical Publishing, Kent, England.
Gell, P. G. H., and Coombs, R. R. A., 1968, Clinical Aspects of Immunology, 2nd ed., F. A. Davis, Philadelphia.
Gershon, R. K., Askenase, P. W., and Gershon, M. D., 1975, Requirement for vasoactive amines for production of delayed-type hypersensitivity skin reactions, J. Exp. Med. 142: 732–747.
Gillespie, E., 1975, Microtubules, cyclic AMP, calcium, and secretion, Ann. N.Y. Acad. Sci. 243: 771–779.
Ginsburg, H., 1963, The in vitro differentiation and culture of normal mast cells from the mouse thymus, Ann. N.Y. Acad. Sci. 103: 20–39.
Ginsburg, H., and Lagunoff, D., 1967, The in vitro differentiation of mast cells. Cultures of cells from immunized mouse lymph nodes and thoracic duct lymph on fibroblast monolayers, J. Cell Biol. 35: 685–697.
Goetzl, E. J., and Austen, K. F., 1977, Generation, function and disposition of chemical mediators of the mast cell in immediate hypersensitivity, in: Immunopharmacology ( J. W. Hadden, R. G. Coffey, and F. Spreafico, eds.), pp. 113–124, Plenum, New York.
Goldman, M. A., Simpson, B. A., and Dvorak, H. F., 1973, Histamine and basophils in delayed-type hypersensitivity reactions, J. Immunol. 110: 1511–1517.
Graham, H. T., Lowry, O. H., Wheelwright, F., Lenz, M. A., and Parrish, H. H., 1955, Distribution of histamine among leukocytes and platelets, Blood 10: 467–481.
Grant, J. A., Dupree, E., Goldman, A. S., Schultz, D. R., and Jackson, A. L., 1975, Complement mediated release of histamine from human leukocytes, J. Immunol. 114: 1101–1106.
Grant, L., 1973, The sticking and emigration of white blood cells in inflammation, in: The Inflammatory Process, Vol. 2, 2nd ed. ( B. W. Zweifach, L. Grant, and R. T. McCluskey, eds.) pp. 205–249, Academic, New York.
Habermann, E., 1972, Bee and wasp venoms, Science 177: 314–322.
Halliwell, R. E. W., 1973, The localization of IgE in canine skin: An immunofluorescent study, J. Immunol. 110: 422–430.
Hartman, W. J., Clark, W. G., and Cyr, S. D., 1961, Histidine decarboxylase activity of basophils from chronic myelogenous leukemic patients. Origin of blood histamine, Proc. Soc, Exp. Biol. Med. 107: 123–125.
Hastie, R., 1971, The antigen-induced degranulation of basophil leukocytes from atopic subjects studied by phase-contrast microscopy, Clin. Exp. Immunol. 8: 45–61.
Hastie, R., 1974, A study of the ultrastructure of human basophil leukocytes, Lab. Invest. 31: 223–231.
Haynes, J. D., Hayden, B. J., and Askenase, P. W., 1974, Cutaneous basophil hypersensitivity (CBH) in neonatal guinea pigs immunized for Jones-Mote reactions (JMR): Active sensitization and passive transfer with immune serum, Fed. Proc. 33: 733.
Haynes, J. D., Kantor, F. S., and Askenase, P. W., 1975, Hapten specific cutaneous basophil hypersensitivity (CBH) transferred with small amounts of 7S IgGI antibody, Fed. Proc. 34: 1039.
Haynes, J. D., Rosenstein, R. W., and Askenase, P. W., 1978, A newly described activity of guinea pig IgG, antibodies: Transfer of cutaneous basophil reactions, J. Immunol. 120: 886–894.
Henderson, W. R., and Kaliner, M., 1978, Immunologic and nonimmunologic generation of super oxide from mast cells and basophils, J. Clin. Invest. 61: 187–196.
Henson, P. M., 1974, Mechanisms of activation and secretion by platelets and neutrophils, in: Progress in Immunology II, Vol. 2 ( L. Brent and J. Holborow, eds.) p. 95, American Elsevier, New York.
Higginbotham, R. D., 1958, Studies on the functional interrelationship of fibroblasts and ground substance mucopolysaccharides, Ann. N.Y. Acad. Sci. 73: 186–203.
Higginbotham, R. D., 1963, in: Round Table Discussion, Conference on Mast Cells and Basophils (J. Padawer, mod.), Ann. N.Y. Acad. Sci. 103: 441–492.
Higginbotham, R. D., Dougherty, T. F., and Jee, W. S. S., 1956, Fate of shed mast cell granules, Proc. Soc. Exp. Biol. Med. 92: 256–261.
Hoenig, E. M., and Levine, S., 1974, Three localized forms of experimental allergic encephalomyelitis: An ultrastructural comparison, J. Neuropathol. Exp. Neurol. 33: 251–259.
Hook, W. A., Siraganian, R. P., and Wuhl, S. M., 1975, Complement induced histamine release from human basophils. I, J. Immunol. 114: 1185–1190.
Horn, R. G., and Spicer, S. S., 1964, Sulfated mucopolysaccharide and basic protein in certain granules of rabbit leukocytes, Lab. Invest. 13: 1–15.
Hubscher, T., Watson, J. I., and Goodfriend, L., 1970a, Target cells of human ragweed-binding antibodies in monkey skin. I. Immunofluorescent localization of cellular binding, J. Immunol. 104: 1187–1195.
Hubscher, T., Watson, J. I., and Goodfriend, L., 1970b, II. Immunoglobulin nature of ragweed binding antibodies with affinity for monkey skin mast cells, J. Immunol. 104: 1196–1204.
Humphrey, J. H., Austen, K. F., and Rapp, H. J., 1963, In vitro studies of reversed anaphylaxis with rat cells, Immunology 6: 226–245.
Ida, S., Hooks, J. J., Siraganian, R. P., and Notkins, A. L., 1977, Enhancement of IgE-mediated histamine release from human basophils by viruses: Role of interferon, J. Exp. Med. 145: 892–906.
Inderbitzin, T., 1956, The relationship of lymphocytes, delayed cutaneous allergic reactions, and histamine, Int. Arch. Allergy Appl. Immunol. 8: 150–159.
Isersky, C., Taurog, J. D., Poy, G., and Metzger, H., 1978, Triggering of cultured neoplastic mast cells by antibodies to the receptor for IgE, J. Immunol. 121: 549–558.
Ishizaka, K., and Ishizaka, T., 1966, Physicochemical properties of reaginic antibody. I. Association of reaginic activity with an immunoglobulin other than yA- or yG-globulin, J. Allergy 37: 169–185.
Ishizaka, K., and Ishizaka, T., 1967, Identification of yE antibodies as a carrier of reaginic activity, J. Immunol. 99: 1187–1198.
Ishizaka, K., and Ishizaka, T., 1969, Immune mechanisms of reversed type reaginic hypersensitivity, J. Immunol. 103: 588–595.
Ishizaka, K., and Ishizaka, T., 1976, Immunoglobulin E, Arch. Pathol. Lab. Med. 100: 289–292.
Ishizaka, K., Tomioka, H., and Ishizaka, T., 1970, Mechanisms of passive sensitization. I. Presence of IgE and IgG molecules on human leukocytes, J. Immunol. 105: 1459–1467.
Ishizaka, T., and Ishizaka, K., 1973, Biological function of immunoglobulin E, in: The Biological Role of the Immunoglobulin E System ( K. Ishizaka and D. H. Dayton, eds.), pp. 33–46, U.S. Government Printing Office, Washington.
Ishizaka, T., and Ishizaka, K., 1974, Mechanisms of passive sensitization. IV. Dissociation of IgE molecules from basophil receptors at acid pH, J. Immunol. 112: 1078–1084.
Ishizaka, T., Ishizaka, K., Johansson, S. G. O., and Bernich, H., 1969, Histamine release from human leukocytes by anti-yE antibodies, J. Immunol. 102: 884–892.
Ishizaka, T., Ishizaka, K., Orange, R. P., and Austen, K. F., 1970, The capacity of human immunoglobulin E to mediate the release of histamine and slow reacting substance of anaphylaxis (SRA-A) from monkey lung, J. Immunol. 104: 335–343.
Ishizaka, T., Ishizaka, K., Orange, R. P., and Austen, K. F., 1971a, Pharmacologic inhibition of the antigen-induced release of histamine and slow reacting substance of anaphylaxis (SRS-A) from monkey lung tissues mediated by human IgE, J. Immunol. 106: 1267–1273.
Ishizaka, T., Tomioka, H., and Ishizaka, K., 1971b, Degranulation of human basophil leukocytes by anti-yE antibody, J. Immunol. 106: 705–710.
Ishizaka, T., Soto, C. S., and Ishizaka, K., 1973, Mechanisms of passive sensitization. III. Number of IgE molecules and their receptor sites on human basophil granulocytes, J. Immunol. 111: 500–511.
Ishizaka, T., Konig, W., Kurata, M., Manser, L., and Ishizaka, K., 1975, Immunologic properties of mast cells from rats infected with Nippostrongylus brasiliensis, J. Immunol. 115: 1078–1083.
Ishizaka, T., Okudaira, H., Manser, L. E., and Ishizaka, K., 1976, Development of rat mast cells in vitro. I. Differentiation of mast cells from thymus cells, J. Immunol. 116: 747–754.
Ishizaka, T., Chang, T. H., Taggart, M., and Ishizaka, K., 1977, Histamine release from rat mast cells by antibodies against rat basophilic leukemia cell membrane. J. Immunol. 119: 1589–1596.
Janoff, A., Schaefer, S., Scherer, J., and Bean, M. A., 1965, Mediators of inflammation in leukocyte lysosomes. II. Mechanism of action of lysosomal cationic protein upon vascular permeability in the rat, J. Exp. Med. 122: 841–851.
Jaques, L. B., Mahadoo, J., and Riley, J. F., 1977, The mast cell/heparin paradox, Lancet 1:411–414. Johansson, S. G. O., and Bennich, H., 1967a, Immunological studies of an atypical (myeloma) immunoglobulin, Immunology 13: 381–394.
Johansson, S. G. O., and Bennich, H., 1967b, Studies on a new class of human immunoglobulins. I. Immunological properties, in: Nobel Symposium 3, Gamma Globulins, Structure and Control of Biosynthesis ( J. Killander, ed.), p. 193, Almqvist and Wiksell, Stockholm.
Johnson, A. R., and Moran, N. C., 1969a, Selective release of histamine from rat mast cells by compound 48/80 and antigen, Am. J. Physiol. 216: 453–489.
Johnson, A. R., and Moran, N. C., 1969b, Release of histamine from rat mast cells: A comparison of the effects of 48/80 and two antigen-antibody systems, Fed. Proc. 28: 1716–1720.
Johnson, A. R., and Moran, N. C., 1970, Inhibition of the release of histamine from rat mast cells: The effect of cold and adrenergic drugs on release of histamine by compound 48/80 and antigen, J. Pharmacol. Exp. Ther. 175: 632–640.
Johnson, A. R., Moran, N. C., and Mayer, S. E., 1974, Cyclic AMP content and histamine release in rat mast cells, J. Immunol. 112: 511–519.
Johnson, A. R., Hugli, T. E., and Müller-Eberhard, H. J., 1975, Release of histamine from rat mast cells by the complement peptides C3a and C5a, Immunology 28: 1067–1080.
Jones, W. O., Rothwell, T. L. W., Dineen, J. K., and Griffiths, D. A., 1974, Studies on the role of histamine and 5-hydroxytryptamine in immunity against the nematode Trichostrongylus colubriformis. II. Amine levels in the intestine of infected guinea-pigs, Int. Arch. Allergy Appl. Immunol. 64: 14–27.
Juhlin, L., 1963, Basophil leukocyte differential in blood and bone marrow. Acta Haematol. 29: 89–95.
Juhlin, L., and Shelley, W. B., 1961, Role of mast cell and basophil in cold urticaria with associated systemic reactions, J. Am. Med. Assoc. 177: 371–377.
Kaliner, M., and Austen, K. F., 1973, A sequence of biochemical events in the antigen-induced release of chemical mediators from sensitized human lung tissue, J. Exp. Med. 138: 1077–1094.
Kaliner, M., and Austen, K. F., 1974, Cyclic AMP, ATP, and reversed anaphylactic histamine release from rat mast cells, J. Immunol. 112: 664–674.
Karnovsky, M. J., and Shea, S. M., 1970, Transcapillary transport by pinocytosis, Microvasc. Res. 2: 353–360.
Katz, S. I., Parker, D., Sommer, G., and TUrk, J. L., 1974, Suppressor cells in normal immunization as a basic homeostatic phenomenon, Nature (London) 248: 612–614.
Kay, A. B., and Austen, K. F., 1972, Chemotaxis of human basophil leukocytes, Clin. Exp. Immunol. 11: 557–563.
Keller, R., 1962, Effect of antibodies against rat y-globulin or rat albumin on isolated peritoneal rat mast cells, Nature (London) 193: 282–283.
Keller, R., 1966, Tissue Mast Cells in Immune Reactions, American Elsevier, New York.
Keller, R., 1968, Interrelations between different types of cells. II. Histamine-release from mast cells of various species by cationic peptides of polymorphonuclear leukocyte lysozymes and other cationic compounds, Int. Arch. Allergy Appl. Immunol. 34: 139–144.
Klebe, R. J., 1974, Isolation of a collagen-dependent cell attachment factor, Nature (London) 250: 248–251.
Kleinman, H. K., Silbert, J. E., and Silbert, C. K., 1975, Heparan sulfate of skin fibroblasts grown in culture, Connect. Tissue Res. 4: 17–23.
Kownatzki, E., Till, G., and Gemsa, D., 1978, Lymphocytes are stimulated by histamine to release an inhibitor of eosinophil chemotactic migration, Z. Immunitaetsforsch. 154: 330.
Kraemer, P. M., 1971, Heparan sulfates of cultured cells. II. Acid-soluble and precipitable species of different cell lines, Biochemistry 10: 1445–1451.
Kraemer, P. M., and Tobay, R. A., 1972, Cell cycle dependent desquamation of heparan sulfate from the cell surface, J. Cell Biol. 55: 713–717.
Lagunoff, D., 1972a, The mechanism of histamine release from mast cells. Biochem. Pharmacol. 21: 1889–1896.
Lagunoff, D., 1972b, Contributions of electon microscopy to the study of mast cells, J. Invest. Dermatol. 58: 296–311.
Lagunoff, D., and Benditt, E. P., 1963, Proteolytic enzymes of mast cells, Ann. N.Y. Acad. Sci. 103: 185–198.
Lasker, S. E., 1977, The heterogeneity of heparins, Fed. Proc. 36: 92–97.
Lett-Brown, M. A., and Leonard, E. J., 1977, Histamine-induced inhibition of normal human basophil chemotaxis to C5a, J. Immunol. 118: 815–818.
Lett-Brown, M. A., Boetcher, D. A., and Leonard, E. J., 1976, Chemotactic responses of normal human basophils to C5a and to lymphocyte-derived chemotactic factor, J. Immunol. 117: 246–252.
Lewis, R. A., and Austen, K. F., 1977, Non-respiratory functions of pulmonary cells: The mast cell, Fed. Proc. 36: 2676–2683.
Lichtenstein, L. M., 1968, Mechanisms of allergic histamine release from human leukocytes, in: Biochemistry of the Acute Allergic Reactions ( K. F. Austen and E. L. Becker, eds.), pp. 153–171, F. A. Davis, Philadelphia.
Lichtenstein, L. M., 1971, The immediate allergic response: In vitro separation of antigen activation, decay, and histamine release, J. Immunol. 107: 1122–1130.
Lichtenstein, L. M., 1975a, Sequential analysis of the allergic response: Cyclic AMP, calcium and histamine, Int. Arch. Allergy Appl. Immunol. 49: 143–154.
Lichtenstein L. M., 1975b, The mechanism of basophil histamine release induced by antigen and by the calcium ionophore A23187, J. Immunol. 114: 1692–1698.
Lichtenstein, L. M., 1976, Hormone receptor interaction in the control of allergic and inflammatory reactions, in: The Role of Immunological Factors in Infectious, Allergic, and Autoimmune Processes ( R. F. Beers and E. G. Bassett, eds.), p. 339, Raven, New York.
Lichtenstein, L. M., and Conroy, M. C., 1977, The “releasability” of mediators from human basophils and granulocytes, in: Ninth International Congress of Allergology, Buenos Aires ( E. Mathov, ed.), pp. 109–115, Excerpta Medica, Amsterdam.
Lichtenstein, L. M., and DeBernardo, R., 1971, The immediate allergic response: In vitro action of cyclic AMP-active and other drugs on the two stages of histamine release, J. Immunol. 107: 1131–1136.
Lichtenstein, L. M., and Gillespie, E., 1973, Inhibition of histamine release by histamine is controlled by an H2 receptor, Nature (London) 244: 287–288.
Lichtenstein, L. M., and Gillespie, E., 1975, The effects of the H, and H2 antihistamines on “allergic” histamine release and its inhibition by histamine, J. Pharmacol. Exp. Ther. 192: 441–450.
Lichtenstein, L. M., and Henney, C. S., 1974, Adenylate cyclase-linked hormone receptors: An important mechanism for the immunoregulation of leukocytes, in: Progress in Immunology II, Vol. 2 ( L. Brent and J. Holborow, eds.) pp. 73–83, North-Holland, Amsterdam.
Lichtenstein, L. M., and Margolis, S., 1968, Histamine release in vitro: Inhibition by catecholamines and methylxanthines, Science 161: 902–903.
Lichtenstein, L. M., and Osier, A. G., 1966a, Studies on the mechanisms of hypersensitivity phenomena. XI. The effect of normal human serum on the release of histamine from human leukocytes by ragween pollen antigen, J. Immunol. 96: 159–168.
Lichtenstein, L. M., and Osier, A. G., 1966b, Studies on the mechanisms of hypersensitivity phenomena. XII. An in vitro study of the reaction between ragweed pollen antigen, allergic human serum and ragweed-sensitive human leukocytes, J. Immunol. 96: 169–179.
Lichtenstein, L. M., Norman, P. S., Winkenwerder, W. L., and Osier, A. G., 1966, In vitro studies of human ragweed allergy: Changes in cellular and humoral activity associated with specific desensitization, J. Clin. Invest. 45: 1126–1136.
Lichtenstein, L. M., Norman, P. S., and Connell, J. T., 1967, Comparison between skin-sensitizing antibody titers and leukocyte sensitivity measurements as an index of the severity of ragweed hay fever, J. Allergy 40: 160–167.
Lichtenstein, L. M., Holtzman, N. A., and Burnett, L. S., 1968, A quantitative in vitro study of the chromatographic distribution and immunoglobulin characteristics of human blocking antibody, J. Immunol. 101: 317–324.
Lichtenstein, L. M., Gillespie, E., and Bourne, H., 1973a, Studies on the biochemical mechanisms of IgE-mediated histamine release, in: The Biological Role of the Immunoglobulin E System ( K. Ishizaka and D. H. Dayton, eds.), pp. 165–180, U.S. Government Printing Office, Washington.
Lichtenstein, L. M., Henney, C. S., Bourne, H. R., and Greenough, W. B., 1973b, III. Effects of cholera toxin on in vitro models of immediate and delayed hypersensitivity. Further evidence for the role of cyclic adenosine 3’,5’-monophosphate, J. Clin. Invest. 52: 691–697.
Lichtenstein, L. M., Sobotka, A. K., Malveaux, F. J., and Gillespie, E., 1978, IgE-induced changes in human basophil cyclic AMP levels, Int. Arch. Allergy Appl. Immunol. 56: 473–478.
Lindell, S. E., Rorsman, H., and Westling, H., 1961, Histamine formation in human blood, Acta Allergol. 16: 216–227.
Lippman, M. M., and Mathews, M. B., 1977, Heparins: Varying effects on, cell proliferation in vitro and lack of correlation with anticoagulant activity, Fed. Proc. 36: 55–59.
Loeffler, L. J., Lorenberg, W., and Sjoerdsma, A., 1971, Effects of dibutyryl-3’-5’ cyclic adenosine monophosphate, phosphodiesterase inhibitors and prostaglandin E, on compound 48/80-induced histamine release from rat peritoneal mast cells in vitro, Biochem. Pharmacol. 20: 2287–2297.
Malveaux, F. J., Conroy, M. C., Adkinson, N. F., Jr., and Lichtenstein, L. M., 1978, IgE receptors on human basophils: Relationship to serum IgE concentration, J. Clin. Invest. 62: 176–181.
Mann, P. R., 1969a, An electron microscopic study of the degranulation of rat peritoneal mast cells brought about by four different agents, Br. J. Dermatol. 81: 926–936.
Mann, P. R., 1969b, An electron microscopic study of the relations between mast cells and eosinophil leukocytes, J. Pathol. 98: 183–186.
Marone, G., and Lichtenstein, L. M., 1978, Adenosine-adenosine deaminase modulation of histamine release, J. Allergy Clin. Immunol. 61: 131.
Mayrhofer, G., Bazin, H., and Gowans, J. L., 1976, Nature of cells binding anti-IgE in rats immunized with Nippostrongylus brasiliensis: IgE synthesis in regional nodes and concentrations in mucosal mast cells, Eur. J. Immunol. 6: 537–545.
McCluskey, R. T., Hall, C. L., and Colvin, R. B., 1978, Immune complex mediated diseases, Hum. Pathol. 9: 71–84.
Medenica, M., and Rostenberg, A., 1971, A comparative light and electron microscopic study of primary irritant contact dermatitis and allergic contact dermatitis, J. Invest. Dermatol. 56: 259–271.
Mendoza, G., and Metzger, H., 1976, Disparity of IgE binding between normal and tumor mouse mast cells, J. Immunol. 117: 1573–1578.
Metcalfe, D. D., Lewis, R. A., Silbert, J. E., Rosenberg, R. D., Wasserman, S. I., and Austen, K. F., 1978, Isolation, identification, and characterization of heparin from human lung, Fed. Proc. 37: 1776.
Metzger, H., and Bach, M. K., 1978, The receptor for IgE on mast cells and basophils: Studies on IgE binding and on the structure of the receptor, in: Immediate Hypersensitivity: Modern Concepts and Developments ( M. K. Bach, ed.), pp. 561–588, Dekker, New York.
Michels, N. A., 1938, The mast cells, in: Handbook of Hematology, Vol. 1 (H. Downey, ed.), pp. 232–372, Hoeber, New York. Reprinted in Ann. N.Y. Acad. Sci. 103: Appendix, 1–372, 1963.
Miller, H. R. P., 1971, Immune reaction in mucous membranes. II. The differentiation of intestinal mast cells during helminth expulsion in the rat, Lab. Invest. 24: 339–347.
Mongar, J. L., and Perera, B. A. V., 1965, Oxygen consumption during histamine release by antigen and compound 48/80, Immunology 8: 511–518.
Mongar, J. L., and Schild, H. 0., 1957, Effect of temperature on the anaphylactic reaction, J. Physiol. (London) 135: 320–338.
Morrison, D. C., 1978, Receptor modulation and mast cell secretion, J. Invest. Dermatol. 71: 85–91.
Morrison, D. C., and Henson, P. M., 1978, Release of mediators from mast cells and basophils induced by different stimuli, in: Immediate Hypersensitivity: Modern Concepts and Develop ments ( M. K. Bach, ed.), pp. 431–502, Dekker, New York.
Morrison, D. C., Roser, J. F., Cochrane, C. G., and Henson, P. M., 1975a, Two distinct mechanisms for the initiation of mast cell degranulation, Int. Arch. Allergy Appl. Immunol. 49: 172–178.
Morrison, D. C., Roser, J. F., Henson, P. M., and Cochrane, C. G., 1975b, Isolation and characterization of a noncytotoxic mast cell activator from cobra venom, Inflammation 1: 103–115.
Mosesson, M. W., 1978, Structure of human plasma cold-insoluble globulin and the mechanism of its precipitation in the cold with heparin or fibrin-fibrinogen complexes, Ann. N.Y. Acad. Sci. 312: 11–30.
Musson, R. A., and Becker, E. L., 1977, The role of an activatable esterase in immune-dependent phagocytosis by human neutrophils, J. Immunol. 118: 1354–1365.
Newball, H. H., Talamo, R. C., and Lichtenstein, L. M., 1975, Release of leukocyte kallikrein mediated by IgE, Nature (London) 254: 635–636.
Nichols, B. A., and Bainton, D. F., 1973, Differentiation of human monocytes in bone marrow and blood: Sequential formation of two granule populations, Lab. Invest. 29: 27–40.
Norman, P. S., Lichtenstein, L. M., and Ishisaka, K., 1973, Diagnostic tests in ragweed hay fever, J. Allergy Clin. Immunol. 52: 210–224.
Norn, S., 1965, Influence of anti-rheumatic agents on the release of histamine from rat peritoneal mast cells after an antigen-antibody reaction, Acta Pharmacol. Toxicol. 22: 369–378.
Olsson, I., 1969, The intracellular transport of glycosaminoglycans (mucopolysaccharides) in human leukocytes, Exp. Cell Res. 54: 318–324.
Olsson, I., 1971, Mucopolysaccarides of rabbit bone marrow cells, Exp. Cell Res. 67: 416–426.
Olsson, I., Garde11, S., and Thunell, S., 1968, Biosynthesis of glycosaminoglycans (mucopolysaccarides) in human leukocytes, Biochim. Biophys. Acta 165: 309–323.
Orange, R. P., Austen, W. G., and Austen, K. F., 1971, Immunologic release of histamine and slow reacting substance of anaphylaxis from human lung. I. Modulation by agents influencing cellular levels of cyclic 3’,5’-adenosine monophosphate, J. Exp. Med. 134: 163S - 148S.
Orenstein, N. S., Hammond, M. E., Dvorak, H. F., and Feder, J., 1976, Esterase and protease activity of purified guinea pig basophil granules, Biochem. Biophys. Res. Communun. 72: 230–235.
Orenstein, N. S., Galli, S. J., Hammond, M. E., Smith, G. N., Silbert, J. E., and Dvorak, H. F., 1977, Mucopolysacchiarides synthesized by guinea pig basophilic leukocytes, Fed. Proc. 36: 1329.
Orenstein, N. S., Galli, S. J., Dvorak, A. M., Silbert, J. E., and Dvorak, H. F., 1978, Sulfated glycosaminoglycans of guinea pig basophilic leukocytes. J. Immunol. 121: 586–592.
Osler, A. G., Lichtenstein, L. M., and Levy, D. A., 1968, In vitro studies of human reaginic allergy, Adv. Immunol. 8: 183–231.
Ovary, Z., 1968, Histology of PCA reactions in guinea pigs. A comparison of reactions produced by guinea pig yGl and rabbit antibodies, J. Immunol. 100: 159–168.
Padawer, J., 1969, Uptake of colloidal thorium dioxide by mast cells, J. Cell Biol. 40: 747–760.
Padawer, J., 1970, The reaction of rat mast cells to polylysine, J. Cell Biol. 47: 352–372.
Padawer, J., 1971, Phagocytosis of particulate substances by mast cells, Lab. Invest. 25: 320–330.
Padawer, J., 1974, Mast cells: Extended lifespan and lack of granule turnover under normal in vivo conditions, Exp. Mol. Pathol. 20: 269–280.
Padawer, J., 1978, The mast cell and immediate hypersensitivity, in: Immediate Hypersensitivity: Modern Concepts and Developments ( M. K. Bach, ed.), pp. 301–367, Dekker, New York.
Parish, W. E., 1978, Evidence for human IgG antibodies anaphylactically sensitizing man, in: Immediate Hypersensitivity: Modern Concepts and Developments ( M. K. Bach, ed.), pp. 277–299, Dekker, New York.
Pearce, F. L., Behrendt, H., Blum, U., Poblete-Freund, G., Pult, P., Stang-Voss, C., and Schmutzler, W., 1977, Isolation and study of functional mast cells from lung and mesentery of the guinea pig, Agents Actions 7: 45–56.
Pearlstein, E., 1976, Plasma membrane glycoprotein which mediates adhesion of fibroblasts to collagen, Nature (London) 262: 497–500.
Pearlstein, E., and Gold, L. I., 1978, High-molecular-weight glycoprotein as a mediator of cellular adhesion, Ann. N.Y Acad. Sci. 312: 278–292.
Pepys, J., Turner-Warwick, M., Dawson, P. L., and Hinson, K. R. W., 1968, in: Allergology, No. 162 (E. Rose, R. Richter, A. Shehon, and A. W. Frankland, eds.), p. 221, Excerpta Medica Foundation, Amsterdam.
Pepera, B. A. V., and Mongar, J. L., 1963, The role in anaphylaxis of a chymotrypsin-like enzyme in rat mast cells, Immunology 6: 478–483.
Perera, B. A. V., and Mongar, J. L., 1965, Effect of anoxia, glucose and thioglycollate on anaphylactic and compound 48/80-induced histamine release in isolated rat mast cells, Immunology 8: 519–525.
Petersson, B. A., Nilsson, A., and Stalenheim, G., 1975, Induction of histamine release and desensitization in human leukocytes—Effect of anaphylatoxin, J. Immunol. 114: 1581–1584.
Plaut, M., and Lichtenstein, L. M., 1978, Pharmacologic control of mediator release, in: Immediate Hypersensitivity: Modern Concepts and Developments ( M. K. Bach, ed.), pp. 503–532, Dekker, New York.
Plaut, M., Lichtenstein, L. M., Gillespie, E., and Henney, C. S., 1973, Studies on the mechanism of lymphocyte-mediated cytolysis. IV. Specificity of the histamine receptor on effector T-cells, J. Immunol. 111: 389–394.
Plant, M., Lichtenstein, L. M., and Henney, C. S., 1975, Modulation of immediate hypersensitivity and cell-mediated immunity: The role of histamine, in: Immunopharmacology ( M. Rosenthale and H. Mansmann, eds.), p. 57, Spectrum, Holliswood, New York.
Pruzansky, J. J., and Patterson, R., 1967, Subcellular distribution of histamine in human leukocytes, Proc. Soc. Exp. Biol. Med. 124: 56–59.
Pruzansky, J. J., and Patterson, R., 1975, The diisopropylfluorophosphate inhibitable step in antigen-induced histamine release from human leukocytes, J. Immunol. 114: 939–943.
Ranadive, N. S., and Cochrane, C. G., 1968, Isolation and characterization of permeability factors from rabbit neutrophils, J. Exp. Med. 128: 605–622.
Ranadive, N. S., and Cochrane, C. G., 1970, Basic proteins in rat neutrophils that increase vascular permeability, Clin. Exp. Immunol. 6: 905–911.
Ranadive, N. S., and Cochrane, C. G., 1971, Mechanism of histamine release from mast cells by cationic protein (band 2) from neutrophil lysosomes, J. Immunol. 106: 506–516.
Ranadive, N. S., and Muir, J. D., 1972, Similarities in the mechanism of histamine release induced by cationic protein from neutrophils and by complement dependent Ag-Ab reaction, Int. Arch. Allergy Appl. Immunol. 42: 236–249.
Ranadive, N. S., and Ruben, D. H., 1973, Mechanism of histamine release from rat mast cells by compound 48/80: Comparison with the release induced by cationic protein, Int. Arch. Allergy Appl. Immunol. 44: 745–758.
Richerson, H. B., 1971, Cutaneous basophil (Jones-Mote) hypersensitivity after “tolerogenic” doses of intravenous ovalbumin in the guinea pig, J. Exp. Med. 134: 630–641.
Richerson, H. B., Dvorak, H. F., and Leskowitz, S., 1969, Cutaneous basophilic hypersensitivity: A new interpretation of the Jones-Mote reaction, J. Immunol. 103: 1431–1434.
Richerson, H. B., Dvorak, H. F., and Leskowitz, S., 1970, Cutaneous basophil hypersensitivity. I. A new look at the Jones-Mote reaction, general characteristics, J. Exp. Med. 132: 546–557.
Riley, J. F., 1959, The Mast Cells, Livingstone, Edinburgh.
Roberts, L. J., II., Lewis, R. A., Hansbrough, R., Austen, K. F., and Oates, J. A., 1978, Biosynthesis of prostaglandins, thromboxanes, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid by rat mast cells, Fed. Proc. 37: 284.
Rocklin, R. E., 1975, Regulation of migration inhibitory factor (MIF) production by histamine receptor-bearing lymphocytes, Fed. Proc. 34: 977.
Rocklin, R. E., 1976, Modulation of cellular-immune responses in vivo and in vitro by histamine receptor-bearing lymphocytes, J. Clin. Invest. 57: 1051–1058.
Röhlich, P., Anderson, P., and Uvnäs, B., 1971, Electron microscopic observations on compound 48/ 80 induced degranulation in rat mast cells. Evidence for sequential exocytosis of storage granules, J. Cell Biol. 51: 465–483.
Rothwell, T. L. W., 1974, Studies of the responses of basophil and eosinophil leukocytes and mast cells to the nematode Trichostrongylus colubriformis. I. Observations during the expulsion of first and second infections by guinea pigs, J. Pathol. 116: 51–60.
Rothwell, T. L. W., and Dineen, J. K., 1972, Cellular reactions in guinea pigs following primary and challenge infection with Trichostrongylus colubriformis with special reference to roles played by eosinophils and basophils in rejection of the parasite, Immunology 22: 733–745.
Rothwell, T. L. W., and Love, R. J., 1975, Studies of the responses of basophil and eosinophil leucocytes and mast cells to the nematode Trichostrongylus colubriformis, II. Changes in cell numbers following infection of thymectomised and adoptively or passively immunised guinea pigs, J. Pathol. 116: 183–194.
Rothwell, T. L. W., Jones, W. O., and Love, R. J., 1974a, Studies on the role of histamine and 5hydroxytryptamine in immunity against the nematode Trichostrongylus colubriformis, III. Inhibition of worm expulsion from guinea pigs by treatment with reserpine, Int. Arch. Allergy Appl. Immunol. 47: 875–886.
Rothwell, T. L. W., Prichard, R. K., and Love, R. J., 1974b, Studies on the role of histamine and 5-hydroxytryptamine in immunity against the nematode Trichostrongylus colubriformis. I. In vivo and in vitro effects of the amines, Int. Arch. Allergy Appl. Immunol. 46: 1–13.
Rubin, R. P., 1974, Calcium and the Secretory Process, Plenum, New York.
Ruoslahti, E., and Engvall, E., 1978, Immunochemical and collagen-binding properties of fibronectin, in: Fibroblast Surface Protein (A. Vaheri, E. Ruoslahti, and D. Mosher, eds.), Ann. N.Y. Acad. Sci. 312: 178–191.
Russell, J. D., Russell, S. B., and Trupin, K. M., 1977, The effect of histamine in the growth of cultured fibroblasts isolated from normal and keloid tissue, J. Cell Physiol. 93: 389–394.
Saeki, K., 1964, Effects of compound 48/80, chymotrypsin and anti-serum on isolated mast cells under aerobic and anaerobic conditions, Jpn. J. Pharmacol. 14: 375–390.
Sampson, D., and Archer, G. T., 1967, Release of histamine from human basophils, Blood 29: 722–736.
Seegers, W., and Janoff, A., 1966, Mediators of inflammation in leukocyte lysosomes. VI. Partial purification and characterization of a mast cell-rupturing component, J. Exp. Med. 124: 833–849.
Segal, D. M., Taurog, J. D., and Metzger, H., 1977, Dimeric immunoglobufin E serves as a unit signal for mast cell degranulation, Proc. Natl. Acad. Sci. USA. 74: 2933–2997.
Shelley, W. B., and Juhlin, L., 1961, New test for detecting anaphylactic sensitivity: Basophil reaction, Nature (London) 191: 1056–1058.
Simson, J. A. V., Hintz, D. S., Munster, A. M., and Spicer, S. S., 1977, Immunocytochemical evidence for antibody binding to mast cell granules, Exp. Mol. Pathol. 26: 85–91.
Siraganian, R. P., 1977, Automated histamine analysis for in vitro allergy testing. II. Correlation of skin test results with in vitro whole blood histamine release in 82 patients, J. Allergy Clin. Immunol. 59: 214–222.
Siraganian, R. P., and Brodsky, M. J., 1976, Automated histamine analysis for in vitro allergy testing. I. A method utilizing allergen induced histamine release from whole blood, J. Allergy Clin. Immunol. 57: 525–540.
Siraganian, R. P., and Hook, W. A., 1976, Complement-induced histamine release from human basophils. II. Mechanism of the histamine release reaction, J. Immunol. 116: 639–646.
Siraganian, R. P., and Levine, B. B., 1975, Unique serum requirement for histamine release from human basophils, Int. Arch. Allergy Appl. Immunol. 48: 530–536.
Siraganian, R. P., and Siraganian, P. A., 1975, Mechanism of action of concanavalin A on human basophils, J. Immunol. 114: 886–893.
Smith, R. T., and vonKorff, R. W., 1957, A heparin-precipitable fraction of human plasma. I. Isolation and characterization of the fraction, J. Clin. Inves. 36: 596–604.
Solley, G. O., Gleich, G. J., Jordan, R. E., and Schroeter, A. L., 1976, The late phase of the immediate wheal and flare skin reaction, J. Clin. Invest. 58: 403–420.
Soter, N. A., and Austen, K. F., 1976, The diversity of mast cell-derived mediators: Implications for acute, subacute, and chronic cutaneous inflammatory disorders, J. Invest. Dermatol. 67: 313–319.
Spicer, S. S., Simson, J. A. V., and Farrington, J. E., 1975, Mast cell phagocytosis of red blood cells, Am. J. Pathol. 80: 481–498.
Stadecker, M. J., and Leskowitz, S., 1976, The inhibition of cutaneous basophil hypersensitivity reactions by a heterologous anti-guinea pig T cell serum, J. Immunol. 116: 1646–1651.
Stadecker, M. J., Lukic, M., Dvorak, A. M., and Leskowitz, S., 1977, The cutaneous basophil response to phytohemagglutinin in chickens, J. Immunol. 118: 1564–1568.
Stallman, P. J., and Aalberse, R. C., 1977a, Estimates of basophil-bound IgE by quantitative immunofluorescence microscopy, Int. Arch. Allergy Appl. Immunol. 54: 9–18.
Stallman, P. J., and Aalberse, R. C., 1977b, Quantitation of basophil-bound IgE in atopic and monotopic subjects, Int. Arch. Allergy Appl. Immunol. 54: 114–120.
Stallman, P. J., Aalberse, R. C., Brühl, P. C., and van Elven, E. H., 1977a, Experiments in the passive sensitization of human basophils, using quantitative immunofluoresence microscopy, Int. Arch. Allergy Appl. Immunol. 54: 364–373.
Stallman, P. J., Wagenaar, S. S., Sevierenga, J., van der Wal, R. J., and Feltkamp-Vroom, T. M., 1977b, Cell-bound IgE on human mast cells and basophilic granulocytes in atopic and non-atopic subjects, Mt. Arch Allergy Appl. Immunol. 54: 443–450.
Stanworth, D. R., Humphrey, J. H., Bennich, H., and Johansson, S. G. O., 1967, Specific inhibition of the Prausnitz-Kästner reaction by an atypical human myeloma protein, Lancet 2: 330–332.
Stanworth, D. R., Humphrey, J. H., Bennich, H., and Johansson, S. G. O., 1968, Inhibition of Prausnitz-Kästner reaction by proteolytic cleavage fragments of a human myeloma protein of immunoglobulin class E, Lancet 2: 17–18.
Stashenko, P. P., Bhan, A. K., Schlossman, S. F., and McCluskey, R. T., 1977, Local transfer of delayed hypersensitivity and cutaneous basophil hypersensitivity, J. Immunol. 119: 1987–1993.
Stathakis, N. E., and Mosesson, M. W., 1977, Interactions among heparin, cold-insoluble globulin, and fibrinogen in formation of the heparin precipitable fraction of plasma, J. Clin. Invest. 60: 855–865.
Stechschulte, D. J., 1978, Non-IgE homocytotropic antibody in animals, in: Immediate Hypersensitivity: Modern Concepts and Developments ( M. K. Bach, ed.), pp. 259–276, Dekker, New York.
Stechschulte, D. J., and Austen, K. F., 1974, Anaphylaxis, in: The Inflammatory Process, Vol. 3, 2nd ed. ( B. W. Zweifach, L. Grant, and R. T. McCluskey, eds.), pp. 237–276, Academic, New York.
Sue, T. K., and Jaques, L. B., 1974, Sulfated mycopolysaccharides and basophilic leukocytes in rabbits on a high cholesterol/oil diet, Proc. Soc. Exp. Biol. Med. 146: 1006–1013.
Sue, T. K., and Jaques, L. B., 1976, Susceptibility to experimental atherosclerosis: Relation to mast cells and heparin, Atherosclerosis 25: 137–139.
Sullivan, A. L., Grimley, P. M., and Metzger, H., 1971, Electron microscopic localization of immunoglobulin E on the surface membrane of human basophils, J. Exp. Med. 134: 1403–1416.
Sullivan, T. J., Parker, K. L., Stenson, W., and Parker, C. W., 1975a, Modulation of cyclic AMP in purified rat mast cells. I. Responses to pharmacologic, metabolic, and physical stimuli, J. Immunol. 114: 1473–1479.
Sullivan, T. J., Parker, K. L., Eisen, S. A., and Parker, C. W., 1975b, Modulation of cyclic AMP in purified rat mast cells. II. Studies on the relationship between intracellular cyclic AMP concentrations and histamine release, J. Immunol. 114: 1480–1485.
Sullivan, T. J., Parker, K. L., Kulczycki, A., Jr., and Parker, C. W., 1976, Modulation of cyclic AMP in purified rat mast cells. III. Studies on the effects of concanavalin A and anit-IgE on cyclic AMP concentrations during histamine release, J. Immunol. 117: 713–716.
Taylor, W. A., and Sheldon, D., 1974, Mast cell degranulation: A comparison of the inhibitory actions of disodium cromoglycate, drugs known to influence the level of intracellular cyclic nucleotide and diisopropylfluorophosphate (DFP), Int. Arch. Allergy Appl. Immunol. 47: 696–707.
Theoharides, T. C., and Douglas, W. W., 1978, Secretion in mast cells induced by calcium entrapped within phospholipid vesicles, Science 201: 1143–1145.
Theuson, D. O., Speck, L., and Grant, J. A., 1977, Histamine-releasing activity produced by human mononuclear cells, Fed. Proc. 36: 1300.
Theuson, D. O., Lett-Brown, M. A., and Grant, J. A., 1979, Histamine release from basophils by mononuclear cell culture supernatants, Fed. Proc. 38: 1459.
Thon, I. L., and Uvnäs, B., 1966, Mode of storage of histamine in mast cells, Acta Physiol. Scand. 67: 455–470.
Tomioka, H., and Ishizaka, K., 1971, Mechanisms of passive sensitization. II. Presence of receptors for IgE on monkey mast cells, J. Immunol. 107: 971–978.
Trotter, C. M., and Orr, T. S. C., 1973, A fine structure study of some cellular components in allergic reactions. I. Degranulation of human mast cells in allergic asthma and perennial rhinitis, Clin. Allergy 3: 411–425.
Trotter, C. M., and Orr, T. C. S., 1974, A fine structure study of some cellular components in allergic reactions. II. Mast cells in normal and atopic human skin, Clin. Allergy 4: 421–433.
Uvnäs, B., and Antonsson, J., 1963, Triggering action of phophatidase A and chymotrypsins on degranulation of rat mesentery mast cells, Biochem. Pharmacol. 12: 867–873.
Uvnäs, B., and Thon, I., 1966, A physico-chemical model of histamine release from mast cells, in: Mechanisms of Release of Biogenic Amines, Proceedings of the International Wenner-Gren Symposium, Stockholm 1965, pp. 361–370, Pergamon, Oxford.
Uvnäs, B., Aborg, C.-H., and Bergendorff, A., 1970, Storage of histamine in mast cell. Evidence for an ionic binding of histamine to protein carboxyls in the granule heparin-protein complex, Acta Physiol. Scand. 78: Suppl. 336: 3–26.
Valentine, M. D., Bloch, K. J., and Austen, K. F., 1967, Mechanisms of immunologic injury of rat peritoneal mast cells. III. Cytotoxic histamine release, J. Immunol. 99: 98–110.
Valentine, W. N., Lawrence, J. S., Pearce, M. L., and Beck, W. S., 1955, The relation of the basophil to blood histamine in man, Blood 10: 154–159.
Van Arsdel, P. P., Jr., and Bray, R. E., 1961, On the release of histamine from rat peritoneal mast cells by compound 48/80: Effects of metabolic inhibitors, J. Pharmacol. Exp. Ther. 133: 319–324.
van Elven, E. H., Stallman, P. J., and Brühl, P. C., 1977, Electron microscopic studies on human basophils from atopic and nonatopic subjects, using horse radish peroxidase labelled anti-IgE, Int. Arch. Allergy Appl. Immunol. 54: 560–567.
Waldmann, T. A., 1969, Disorders of immunoglobulin metabolism, New Engl. J. Med. 281: 1170–1177.
Waldmann, T A, Iio, A., Ogawa, M., McIntyre, O. R., and Strober, W., 1976, The metabolism of IgE. Studies in normal individuals and in a patient with IgE myeloma, J. Immunol. 117: 1139–1144.
Ward, P. A., Offen, C. D., and Montgomery, J. R., 1971, Chemoattractants of leukocytes, with special reference to lymphocytes, Fed. Proc. 30: 1721–1724.
Ward, P. A., Dvorak, H. F., Cohen, S., Yoshida, T., Data, R., and Selvaggio, S. S., 1975, Chemotaxis of basophils by lymphocyte-dependent and lymphocyte-independent mechanisms, J. Immunol. 114: 1523–1531.
Wasserman, S. I., Goetzl, E. J., and Austen, K. F., 1974a, Preformed eosinophil chemotactic factor of anaphylaxis (ECF-A), J. Immunol. 112: 351–358.
Wasserman, S. I., Goetzl, E. J., Kaliner, M., and Austen, K. F., 1974b, Modulation of the immunological release of the eosinophil chemotactic factor of anaphylaxis from human lung, Immunology 26: 677–684.
Werb, Z., and Aggeler, J., 1978, Proteases induce secretion of collagenase and plasminogen activator by fibroblasts, Proc. Natl. Acad. Sci. USA 75: 1839–1843.
Wikel, S. K., and Allen, J. R., 1976, Acquired resistance to ticks. I. Passive transfer of resistance, Immunology 30: 311–316.
Wintroub, B. U., Mihm, M. C., Jr., Goetzl, E. J., Soter, N. A., and Austen, K. F., 1978, Morphologic and functional evidence for release of mast-cell products in bullous pemphigoid, New Engl. J. Med. 298: 417–421.
Woodin, A. M., and Wieneke, A. A., 1970, Action of DFP on the leukocyte and the axon, Nature (London) 227: 460–463.
Yamasaki, H., and Saeki, K., 1967, Inhibition of mast cell degranulation by anti-inflammatory agents, Arch. Int. Pharmacodyn. Ther. 168: 166–179.
Yurt, R., and Austen, K. F., 1977, Preparative purification of the rat mast cell chymase: Characterization and interaction with granule components. J. Exp. Med. 146: 1405–1419.
Yurt, R. W., Leid, R. W., Jr., Spragg, J., and Austen, K. F., 1977a, Native heparin from rat peritoneal mast cells, J. Biol. Chem. 252: 518–521.
Yurt, R. W., Leid, R. W., Jr., Spragg, J., and Austen, K. F., 1977b, Immunologic release of heparin from purified rat peritoneal mast cells, J. Immunol. 118: 1201–1207.
Zeiger, R. S., Twarog, F. J., and Colten, H. R., 1976a, Histaminase release from human granulocytes, J. Exp. Med. 144: 1049–1061.
Zeiger, R. S., Yurdin, D. L., and Colten, H. R., 1976b, Histamine metabolism. II. Cellular and subcellular localization of the catabolic enzymes, histaminase and histamine methyl transferase, in human leukocytes, J. Allergy Clin. Immunol. 58: 172–179.
Zurier, R. B., Hoffstein, S., Kammerman, S., and Tai, H. H., 1974, Mechanisms of lysozomal enzyme release from human leukocytes. II. Effects of cAMP and cGMP, autonomic agonists, and agents whigh affect microtubule function, J. Clin. Invest. 53: 297–309.
Zweiman, B., Slott, R. I., and Atkins, P., 1976, Factors in the tissue eosinophil response in human immediate hypersensitivity reactions, Int. Arch. Allergy Appl. Immunol. 52: 48–52.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Plenum Publishing Corporation
About this chapter
Cite this chapter
Galli, S.J., Dvorak, H.F. (1979). Basophils and Mast Cells: Structure, Function, and Role in Hypersensitivity. In: Gupta, S., Good, R.A. (eds) Cellular, Molecular, and Clinical Aspects of Allergic Disorders. Comprehensive Immunology, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0988-8_1
Download citation
DOI: https://doi.org/10.1007/978-1-4684-0988-8_1
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-0990-1
Online ISBN: 978-1-4684-0988-8
eBook Packages: Springer Book Archive