Abstract
Qualitative methods for determining the chemical composition of cellular structures go quite far back in time. Even in the early days the main interest was the cell nucleus. Overenthusiastic use of these staining techniques brought, however, the field into disrepute especially in the 1920-ies and this came to be one of the main reasons for developing quantitative optical microscopy for cytochemical research.
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© 1979 Springer Science+Business Media New York
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Caspersson, T. (1979). Techniques for Cytochemical Studies of the Nucleus and its Substructures. In: Nicolini, C.A. (eds) Chromatin Structure and Function. NATO Advanced Study Institutes Series, vol 21a. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0973-4_12
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DOI: https://doi.org/10.1007/978-1-4684-0973-4_12
Publisher Name: Springer, Boston, MA
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